| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Henry F Bradfor. The use of foetal human brain tissue as brain implants: phenotype manipulation by genetic manipulation and biochemical induction. The Keio journal of medicine. vol 51. issue 3. 2002-10-29. PMID:12371646. |
in another approach we have biochemically manipulated the development of the cerebral cortex to direct the neurotransmitter phenotype towards the dopaminergic type, and away from other phenotypes. |
2002-10-29 |
2023-08-12 |
human |
| Adam Czapliński, Andreas J Steck, Peter Fuh. [Tic syndrome]. Neurologia i neurochirurgia polska. vol 36. issue 3. 2002-10-23. PMID:12185806. |
based on the review of the literature we believe that tic disorders are related to altered neurotransmitter function within the cns, especially that the functional abnormality is somehow related to dopaminergic mechanism. |
2002-10-23 |
2023-08-12 |
Not clear |
| Robyn Lints, Scott W Emmon. Regulation of sex-specific differentiation and mating behavior in C. elegans by a new member of the DM domain transcription factor family. Genes & development. vol 16. issue 18. 2002-10-17. PMID:12231628. |
in the male nervous system, mab-23 refines ray neuron subtype distribution by restricting expression of dopaminergic neurotransmitter identity through interactions with the hox gene egl-5 and a tgf-beta-related signaling pathway. |
2002-10-17 |
2023-08-12 |
caenorhabditis_elegans |
| Sanjeev Choudhary, Geetu Raheja, Vandana Gupta, Kiran Dip Gil. Possible involvement of dopaminergic neurotransmitter system in dichlorvos induced delayed neurotoxicity. Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB). vol 6. issue 1. 2002-10-09. PMID:12186780. |
possible involvement of dopaminergic neurotransmitter system in dichlorvos induced delayed neurotoxicity. |
2002-10-09 |
2023-08-12 |
rat |
| Sanjeev Choudhary, Geetu Raheja, Vandana Gupta, Kiran Dip Gil. Possible involvement of dopaminergic neurotransmitter system in dichlorvos induced delayed neurotoxicity. Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB). vol 6. issue 1. 2002-10-09. PMID:12186780. |
the present investigation was carried out to elucidate the possible involvement of the dopaminergic neurotransmitter system in the development of dichlorvos induced delayed neurotoxicity in the rat and to assess the protective efficacy of nimodipine against opidn (organophosphate induced delayed neurotoxicity). |
2002-10-09 |
2023-08-12 |
rat |
| Sanjeev Choudhary, Geetu Raheja, Vandana Gupta, Kiran Dip Gil. Possible involvement of dopaminergic neurotransmitter system in dichlorvos induced delayed neurotoxicity. Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB). vol 6. issue 1. 2002-10-09. PMID:12186780. |
single subcutaneous dose of dichlorvos (200 mg/kg body weight) resulted in marked changes in the dopaminergic neurotransmitter system in terms of increased levels of both dopamine and norepinephrine along with significant increase in the activity of both the catecholamine synthesizing enzymes, tyrosine hydroxylase (th) and dopamine-beta-hydroxylase. |
2002-10-09 |
2023-08-12 |
rat |
| Sanjeev Choudhary, Geetu Raheja, Vandana Gupta, Kiran Dip Gil. Possible involvement of dopaminergic neurotransmitter system in dichlorvos induced delayed neurotoxicity. Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB). vol 6. issue 1. 2002-10-09. PMID:12186780. |
administration of nimodipine, a centrally acting calcium channel blocker, along with dichlorvos restricted all these alterations to within control values and could also ameliorate certain behavioural deficits by maintaining the dopaminergic neurotransmitter system. |
2002-10-09 |
2023-08-12 |
rat |
| Lynette D Fairbanks, Gabriella Jacomelli, Vanna Micheli, Tina Slade, H Anne Simmond. Severe pyridine nucleotide depletion in fibroblasts from Lesch-Nyhan patients. The Biochemical journal. vol 366. issue Pt 1. 2002-10-08. PMID:11996669. |
nad plus atp depletion in developing brain could restrict dna repair, leading to neuronal damage/loss by apoptosis, and, with gtp depletion, affect neurotransmitter synthesis and basal ganglia dopaminergic neuronal systems. |
2002-10-08 |
2023-08-12 |
human |
| M J Arranz, D Collier, R W Kerwi. Pharmacogenetics for the individualization of psychiatric treatment. American journal of pharmacogenomics : genomics-related research in drug development and clinical practice. vol 1. issue 1. 2002-09-18. PMID:12173312. |
these include the dopaminergic and serotonergic receptors, neurotransmitter transporters and other receptors and enzymes involved in psychiatric disorders. |
2002-09-18 |
2023-08-12 |
Not clear |
| Jonas Bergquist, Lil Träskman-Bendz, Mats B Lindström, Rolf Ekma. Suicide-attempters having immunoglobulin G with affinity for dopamine in cerebrospinal fluid. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 2. 2002-08-14. PMID:11872333. |
the results in the present study indicate that an autoimmune mechanism may be involved in the dopaminergic neurotransmitter system and may be of pathophysiological importance in psychiatric disorders connected to an attempt of suicide. |
2002-08-14 |
2023-08-12 |
human |
| A Czyrak, A Chocy. Search for the presence of glucocorticoid receptors in dopaminergic neurons of rat ventral tegmental area and substantia nigra. Polish journal of pharmacology. vol 53. issue 6. 2002-07-19. PMID:11985346. |
above anatomical data indicate that glucocorticoid receptors influence the dopaminergic neurotransmission by an indirect mechanism, which possibly involves intermittent neurotransmitter. |
2002-07-19 |
2023-08-12 |
rat |
| D M Wu, H Kawamura, Q Li, D G Pur. Dopamine activates ATP-sensitive K+ currents in rat retinal pericytes. Visual neuroscience. vol 18. issue 6. 2002-07-08. PMID:12020084. |
because dopaminergic neurites are closely associated with microvessels that express dopamine receptors, this molecule is a putative neuron-to-capillary signal, as well as neurotransmitter. |
2002-07-08 |
2023-08-12 |
rat |
| Michael L Kirby, Rebecca L Barlow, Jeffrey R Bloomquis. Selective effects of cyclodiene insecticides on dopamine release in mammalian synaptosomes. Toxicology and applied pharmacology. vol 181. issue 2. 2002-07-02. PMID:12051992. |
release assays with different transmitters indicated that striatal dopaminergic terminals are severalfold more sensitive to release than other neurotransmitter types. |
2002-07-02 |
2023-08-12 |
Not clear |
| Anthony R West, Matthew P Galloway, Anthony A Grac. Regulation of striatal dopamine neurotransmission by nitric oxide: effector pathways and signaling mechanisms. Synapse (New York, N.Y.). vol 44. issue 4. 2002-06-24. PMID:11984858. |
an important role for the reactive gas nitric oxide (no) in regulating striatal dopaminergic neurotransmission was identified shortly after initial observations indicated that this unorthodox neurotransmitter mediates many of the influences of glutamatergic neurotransmission in the cerebellum, cortex, and hippocampus. |
2002-06-24 |
2023-08-12 |
Not clear |
| T Araki, M Matsubara, K Fujihara, H Kato, Y Imai, Y Itoyam. Gamma-aminobutyric acidA and benzodiazepine receptor alterations in the rat brain after unilateral 6-hydroxydopamine lesions of the medial forebrain bundle. Neurological research. vol 24. issue 1. 2002-06-21. PMID:11783749. |
thus, investigations into possible changes in neurotransmitter receptors other than dopaminergic receptors appear to be important for the elucidation of pathogenesis of parkinsons disease. |
2002-06-21 |
2023-08-12 |
rat |
| T A Slotkin, C A Tate, M M Cousins, F J Seidle. Functional alterations in CNS catecholamine systems in adolescence and adulthood after neonatal chlorpyrifos exposure. Brain research. Developmental brain research. vol 133. issue 2. 2002-05-23. PMID:11882346. |
we then examined the impact on catecholaminergic systems in adolescence (pn30) and adulthood (pn60), assessing basal neurotransmitter content and transmitter utilization rates (turnover) in brain regions comprising the major noradrenergic and dopaminergic projections. |
2002-05-23 |
2023-08-12 |
rat |
| Toshihiko Morimoto, Kenji Hashimoto, Hiroshi Yasumatsu, Hiroshi Tanaka, Masatake Fujimura, Makoto Kuriyama, Koreichi Kimura, Shuzo Takehara, Keiji Yamagam. Neuropharmacological profile of a novel potential atypical antipsychotic drug Y-931 (8-fluoro-12-(4-methylpiperazin-1-yl)- 6H-[1]benzothieno[2,3-b][1,5] benzodiazepine maleate). Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 26. issue 4. 2002-05-09. PMID:11927170. |
similar to clozapine and olanzapine, y-931 interacted with multiple neurotransmitter receptors such as dopaminergic, serotonergic, alpha-adrenergic, muscarinic and histaminergic receptors. |
2002-05-09 |
2023-08-12 |
rat |
| B Dea. Understanding the pathology of schizophrenia: recent advances from the study of the molecular architecture of postmortem CNS tissue. Postgraduate medical journal. vol 78. issue 917. 2002-04-18. PMID:11884695. |
recent findings have shown changes in markers in a number of neurotransmitter systems in the brains of subjects with schizophrenia which include the dopaminergic, serotonergic, cholinergic, glutamatergic, and gabaergic systems of the cns. |
2002-04-18 |
2023-08-12 |
human |
| S Jiang, R Xin, S Lin, Y Qian, G Tang, D Wang, X W. Linkage studies between attention-deficit hyperactivity disorder and the monoamine oxidase genes. American journal of medical genetics. vol 105. issue 8. 2002-03-05. PMID:11803531. |
molecular genetic and pharmacological studies suggest the involvement of dopaminergic and noradrenergic neurotransmitter systems in adhd, e.g., several reports have found association between adhd and the dopamine receptor gene drd-4, the dopamine transporter gene dat1, and the catecholamine clearance enzyme catechol-o-methyltransferase. |
2002-03-05 |
2023-08-12 |
Not clear |
| S R Pliszk. New developments in psychopharmacology of attention deficit hyperactivity disorder. Expert opinion on investigational drugs. vol 10. issue 10. 2002-02-28. PMID:11772286. |
some, like the stimulants, primarily impact the noradrenergic and dopaminergic neurotransmitter systems, while others have novel effects on the cholinergic, histaminergic and peptidergic systems. |
2002-02-28 |
2023-08-12 |
Not clear |