| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucas E Cromberg, Trinidad M M Saez, María G Otero, Eugenia Tomasella, Matías Alloatti, Ana Damianich, Victorio Pozo Devoto, Juan Ferrario, Diego Gelman, Marcelo Rubinstein, Tomás L Falzon. Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors. Journal of neurochemistry. vol 149. issue 3. 2020-03-18. PMID:30664247. |
high pressure liquid chromatography determined that dopamine (da) metabolism is impaired in neuronal kif5b-ko, while no dopaminergic cell loss was observed. |
2020-03-18 |
2023-08-13 |
mouse |
| Yuan-Hao Chen, Tsung-Hsun Hsieh, Tung-Tai Kuo, Jen-Hsin Kao, Kuo-Hsing Ma, Eagle Yi-Kung Huang, Yu-Ching Chou, Lars Olson, Barry J Hoffe. Release parameters during progressive degeneration of dopamine neurons in a mouse model reveal earlier impairment of spontaneous than forced behaviors. Journal of neurochemistry. vol 150. issue 1. 2020-03-13. PMID:30933310. |
to determine the role of reduced dopaminergic transmission for declines of forced versus spontaneous behavior, we used a model of parkinson's disease with progressive degeneration of dopamine (da) neurons, the mitopark mouse. |
2020-03-13 |
2023-08-13 |
mouse |
| Désirée Mineo, Fabrizio Cacace, Maria Mancini, Anna Vannelli, Federica Campanelli, Giuseppina Natale, Gioia Marino, Antonella Cardinale, Paolo Calabresi, Barbara Picconi, Veronica Ghiglier. Dopamine drives binge-like consumption of a palatable food in experimental Parkinsonism. Movement disorders : official journal of the Movement Disorder Society. vol 34. issue 6. 2020-03-13. PMID:31002748. |
prolonged dopaminergic replacement therapy in pd results in pulsatile dopamine receptors stimulation in both dorsal and ventral striatum causing wearing off, motor fluctuations, and nonmotor side effects such as behavioral addictions. |
2020-03-13 |
2023-08-13 |
Not clear |
| Naoko Kuzumaki, Yukari Suda, Chizuru Iwasawa, Michiko Narita, Takefumi Sone, Moe Watanabe, Aya Maekawa, Takuya Matsumoto, Wado Akamatsu, Katsuhide Igarashi, Hideki Tamura, Hideyuki Takeshima, Vivianne L Tawfik, Toshikazu Ushijima, Nobutaka Hattori, Hideyuki Okano, Minoru Narit. Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease. Brain : a journal of neurology. vol 142. issue 6. 2020-03-12. PMID:31135049. |
in dopamine transporter (dat)-cre mice, overexpression of comt, specifically in dopaminergic neurons of the substantia nigra, produced cataleptic behaviours associated with impaired motor coordination. |
2020-03-12 |
2023-08-13 |
mouse |
| Swati Shah, Dragan Maric, Frank Denaro, Wael Ibrahim, Ronald Mason, Ashutosh Kumar, Dima A Hammoud, William Rei. Nitrosative Stress Is Associated with Dopaminergic Dysfunction in the HIV-1 Transgenic Rat. The American journal of pathology. vol 189. issue 7. 2020-03-11. PMID:31230667. |
colocalization of 3-nt staining with neurofilament proteins and evidence of decreased tyrosine hydroxylase and dopamine transporter expression in the old rats support dopaminergic involvement. |
2020-03-11 |
2023-08-13 |
rat |
| J Elliott Robinson, Gerard M Coughlin, Acacia M Hori, Jounhong Ryan Cho, Elisha D Mackey, Zeynep Turan, Tommaso Patriarchi, Lin Tian, Viviana Gradinar. Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1. eLife. vol 8. 2020-03-11. PMID:31545171. |
we employed the genetically encoded optical dopamine sensor dlight1 to monitor dopaminergic neurotransmission in the ventral striatum of nf1 mice during motivated behavior. |
2020-03-11 |
2023-08-13 |
mouse |
| Merve Çapkın Yurtsever, Arlin Kiremitci, Menemşe Gümüşderelioğl. Dopaminergic induction of human dental pulp stem cells by photobiomodulation: comparison of 660nm laser light and polychromatic light in the nir. Journal of photochemistry and photobiology. B, Biology. vol 204. 2020-03-11. PMID:31982670. |
real time rt-qpcr analysis indicated that expressions of brain derived neurotrophic factor (bdnf), glial cell line derived neurotropic factor (gndf), matrix associated protein 2 (map2), nuclear receptor related 1 protein (nurr1) and dopamine transporter (dat) were increased, especially in the first 7 days of dopaminergic induction when 660 nm laser light was applied with a total energy density of 1.6 j/cm |
2020-03-11 |
2023-08-13 |
human |
| Francesca Montarolo, Serena Martire, Simona Perga, Michela Spadaro, Irene Brescia, Sarah Allegra, Silvia De Francia, Antonio Bertolott. NURR1 deficiency is associated to ADHD-like phenotypes in mice. Translational psychiatry. vol 9. issue 1. 2020-03-09. PMID:31455763. |
the transcription factor nurr1 regulates the dopamine (da) signaling pathway and exerts a critical role in the development of midbrain dopaminergic neurons (mda). |
2020-03-09 |
2023-08-13 |
mouse |
| Marina Spanos, Xiaohu Xie, Julie Gras-Najjar, Stephanie C White, Leslie A Somber. NMDA Receptor-Dependent Cholinergic Modulation of Mesolimbic Dopamine Cell Bodies: Neurochemical and Behavioral Studies. ACS chemical neuroscience. vol 10. issue 3. 2020-03-05. PMID:30412381. |
together, these results suggest that acetylcholine and glutamate synergistically act at dopamine cells in the vta to modulate vta-nac shell dopaminergic output, and this underlies motivation to lever press for a motivationally neutral visual stimulus. |
2020-03-05 |
2023-08-13 |
rat |
| Arndt von Twickel, Daniel Kowatschew, Mehmet Saltürk, Maria Schauer, Brita Robertson, Sigrun Korsching, Wolfgang Walkowiak, Sten Grillner, Juan Pérez-Fernánde. Individual Dopaminergic Neurons of Lamprey SNc/VTA Project to Both the Striatum and Optic Tectum but Restrict Co-release of Glutamate to Striatum Only. Current biology : CB. vol 29. issue 4. 2020-03-03. PMID:30713108. |
the combined release of dopamine and glutamate may be appropriate in striatum, whereas the effects exerted on the tectal motor center may be better served with a selective dopaminergic modulation. |
2020-03-03 |
2023-08-13 |
Not clear |
| Polina Kosillo, Natalie M Doig, Kamran M Ahmed, Alexander H C W Agopyan-Miu, Corinna D Wong, Lisa Conyers, Sarah Threlfell, Peter J Magill, Helen S Bateu. Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility. Nature communications. vol 10. issue 1. 2020-03-02. PMID:31780742. |
our results establish a critical role for tsc1-mtorc1 signaling in setting the functional properties of dopamine neurons, and indicate that dopaminergic dysfunction may contribute to cognitive inflexibility in tsc. |
2020-03-02 |
2023-08-13 |
Not clear |
| Shun Zhang, Rui Wang, Guanghui Wan. Impact of Dopamine Oxidation on Dopaminergic Neurodegeneration. ACS chemical neuroscience. vol 10. issue 2. 2020-02-26. PMID:30592597. |
impact of dopamine oxidation on dopaminergic neurodegeneration. |
2020-02-26 |
2023-08-13 |
mouse |
| Roshan Cools, Monja Froböse, Esther Aarts, Lieke Hofman. Dopamine and the motivation of cognitive control. Handbook of clinical neurology. vol 163. 2020-02-26. PMID:31590726. |
consistent with an "inverted-u"-shaped relationship between dopamine and value-based learning, this evidence suggests that dopaminergic drugs might paradoxically increase our drive away from cognitive control in individuals with high baseline levels of dopamine, perhaps by "overdosing" dopamine levels, and thus reducing the value of cognitive control. |
2020-02-26 |
2023-08-13 |
human |
| Michael Silkstone, Stefan M Brudzynsk. The antagonistic relationship between aversive and appetitive emotional states in rats as studied by pharmacologically-induced ultrasonic vocalization from the nucleus accumbens and lateral septum. Pharmacology, biochemistry, and behavior. vol 181. 2020-02-25. PMID:31034853. |
conversely, 50-khz usvs are emitted during positive pro-social contexts and can be initiated by stimulation of ascending dopaminergic pathways originating from the ventral tegmental area or by injection of dopamine agonists into target areas of these pathways (nucleus accumbens shell). |
2020-02-25 |
2023-08-13 |
rat |
| Yuta Miyamoto, Issei Nagayoshi, Akinori Nishi, Takaichi Fukud. Three divisions of the mouse caudal striatum differ in the proportions of dopamine D1 and D2 receptor-expressing cells, distribution of dopaminergic axons, and composition of cholinergic and GABAergic interneurons. Brain structure & function. vol 224. issue 8. 2020-02-24. PMID:31375982. |
three divisions of the mouse caudal striatum differ in the proportions of dopamine d1 and d2 receptor-expressing cells, distribution of dopaminergic axons, and composition of cholinergic and gabaergic interneurons. |
2020-02-24 |
2023-08-13 |
mouse |
| Utkarsha A Singh, Soumya Iyenga. The expression of DARPP-32 in adult male zebra finches (Taenopygia guttata). Brain structure & function. vol 224. issue 8. 2020-02-24. PMID:31473781. |
our results suggest that whereas dopamine may modulate the shell pathways at various levels of the afp, dopaminergic modulation of the core pathway occurs mainly through area x, a basal ganglia nucleus. |
2020-02-24 |
2023-08-13 |
Not clear |
| George R Uh. Dopamine compartmentalization, selective dopaminergic vulnerabilities in Parkinson's disease and therapeutic opportunities. Annals of clinical and translational neurology. vol 6. issue 2. 2020-02-18. PMID:30847375. |
dopamine compartmentalization, selective dopaminergic vulnerabilities in parkinson's disease and therapeutic opportunities. |
2020-02-18 |
2023-08-13 |
Not clear |
| Kun-Ruey Shieh, Shu-Chuan Yan. Formosan wood mice ( The Chinese journal of physiology. vol 63. issue 1. 2020-02-18. PMID:32056984. |
dopamine and its major metabolite 3,4-dihydroxyphenylacetic acid were used as indices of dopaminergic activities. |
2020-02-18 |
2023-08-13 |
mouse |
| Kedong Xu, Pingping Li, Yi Miao, Nan Dong, Jianbo Zhang, Shuguang Wei, Shengbin Li, Fang Ca. Effects of ovarian hormones on emotional behaviors in dopamine D3 receptor knockout mice. Physiology & behavior. vol 198. 2020-02-17. PMID:30292827. |
several studies have provided evidence of the relationship between ovarian hormones and the dopaminergic system, but the interaction between ovarian hormones and dopamine d3 receptor (drd3) is poorly understood. |
2020-02-17 |
2023-08-13 |
mouse |
| Tetsuro Ishii, Eiji Warabi, Giovanni E Man. Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis. Free radical biology & medicine. vol 133. 2020-02-14. PMID:30189266. |
as dopamine can be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative damage and ferroptosis-like induced cell death. |
2020-02-14 |
2023-08-13 |
Not clear |