| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J G Cannon, C Suarez-Gutierrez, T Lee, J P Long, B Costall, D H Fortune, R J Naylo. Rigid congeners of dopamine based on octahydrobenzo[f]quinoline: peripheral and central effects. Journal of medicinal chemistry. vol 22. issue 4. 1979-06-29. PMID:571020. |
the cis isomers are flexible molecules; the dopamine moiety lacks conformational integrity and it can exist in a conformation which is believed not to favor dopaminergic activity. |
1979-06-29 |
2023-08-11 |
Not clear |
| S M Wuerthele, K E Moor. Effects of dopaminergic antagonists on striatal DOPAC concentrations and alpha-methyl-p-tyrosine-induced decline of dopamine following intrastriatal injections of kainic acid. The Journal of pharmacy and pharmacology. vol 31. issue 3. 1979-06-11. PMID:34696. |
effects of dopaminergic antagonists on striatal dopac concentrations and alpha-methyl-p-tyrosine-induced decline of dopamine following intrastriatal injections of kainic acid. |
1979-06-11 |
2023-08-11 |
Not clear |
| Y Agid, P Pollak, A M Bonnet, J L Signoret, F Lhermitt. Bromocriptine associated with a peripheral dopamine blocking agent in treatment of Parkinson's disease. Lancet (London, England). vol 1. issue 8116. 1979-05-26. PMID:85162. |
thus, peripheral blockade of dopamine receptors is a promising means of limiting the adverse side-effects of the treatment of parkinsonism with central dopaminergic receptor stimulating agents such as bromocriptine. |
1979-05-26 |
2023-08-11 |
Not clear |
| W Reimann, A Zumstein, R Jackisch, K Starke, G Herttin. Effect of extracellular dopamine on the release of dopamine in the rabbit caudate nucleus: evidence for a dopaminergic feedback inhibition. Naunyn-Schmiedeberg's archives of pharmacology. vol 306. issue 1. 1979-05-16. PMID:423999. |
effect of extracellular dopamine on the release of dopamine in the rabbit caudate nucleus: evidence for a dopaminergic feedback inhibition. |
1979-05-16 |
2023-08-11 |
rabbit |
| S F Leibowitz, C Rossaki. Analysis of feeding suppression produced by perifornical hypothalamic injection of catecholamines, amphetamines and mazindol. European journal of pharmacology. vol 53. issue 1. 1979-04-25. PMID:738361. |
the effects of amphetamine and epinephrine were abolished by these drugs, while dopamine's effect was selectively inhibited by the dopaminergic antagonist. |
1979-04-25 |
2023-08-11 |
human |
| A Nieoullon, A Cheramy, V Leviel, J Glowinsk. Effects of the unilateral nigral application of dopaminergic drugs on the in vivo release of dopamine in the two caudate nuclei of the cat. European journal of pharmacology. vol 53. issue 3. 1979-03-28. PMID:32060. |
effects of the unilateral nigral application of dopaminergic drugs on the in vivo release of dopamine in the two caudate nuclei of the cat. |
1979-03-28 |
2023-08-11 |
cat |
| O Kuchel, N T Buu, T Unger, J Genes. Free and conjugated catecholamines in human hypertension. Clinical science and molecular medicine. Supplement. vol 4. 1979-03-24. PMID:282103. |
elevated conjugated dopamine appears to reflect a compensatory activation of the dopaminergic vasodilator pathway in hypertension, the total urinary dopamine excretion an intrinsic deficiency or compensatory increase of a dopamine-modulated natriuretic mechanism. |
1979-03-24 |
2023-08-11 |
human |
| H C Fibiger, S T Maso. The effects of dorsal bundle injections of 6-hydroxydopamine on avoidance responding in rats. British journal of pharmacology. vol 64. issue 4. 1979-03-24. PMID:728687. |
4 a comparison with work by other authors in which both forebrain noradrenaline and dopamine were depleted suggest that the alteration in extinction seen in both studies is a noradrenergic effect, whereas the deficits in acquisition and retention found previously are dopaminergic in origin. |
1979-03-24 |
2023-08-11 |
rat |
| N White, Z Brown, M Yachni. Effects of catecholamine manipulations on three different self-stimulation behaviors. Pharmacology, biochemistry, and behavior. vol 9. issue 5. 1979-03-24. PMID:733849. |
at low doses of pimozide (a dopaminergic blocker) or of fla-57 (a dopamine beta-hydroxylase inhibitor) different effects on rates of responding were observed on each of the three tasks at the two electrode placements, indicating that the rate reductions were not the results of specific performance effects of the drugs. |
1979-03-24 |
2023-08-11 |
rat |
| A M Di Giulio, A Groppetti, F Cattabeni, C L Galli, A Maggi, S Algeri, F Ponzi. Significance of dopamine metabolites in the evaluation of drugs acting on dopaminergic neurons. European journal of pharmacology. vol 52. issue 2. 1979-03-13. PMID:729633. |
significance of dopamine metabolites in the evaluation of drugs acting on dopaminergic neurons. |
1979-03-13 |
2023-08-11 |
rat |
| J W Kebabian, P R Kebabia. Lergotrile and lisuride: in vivo dopaminergic agonists which do not stimulate the presynaptic dopamine autoreceptor. Life sciences. vol 23. issue 22. 1979-02-21. PMID:31541. |
lergotrile and lisuride: in vivo dopaminergic agonists which do not stimulate the presynaptic dopamine autoreceptor. |
1979-02-21 |
2023-08-11 |
Not clear |
| P Taylor, P K Gillman, R Gain. Alpha-methyldopa in schizophrenia. The Journal of clinical psychiatry. vol 39. issue 11. 1979-02-21. PMID:721785. |
the dopamine hypothesis of schizophrenia suggests that there is a functional excess of dopaminergic activity within the brain of schizophrenics. |
1979-02-21 |
2023-08-11 |
Not clear |
| D Eccleston, N Nicolao. The influence of L-tryptophan and monoamine oxidase inhibitors on catecholamine metabolism in rat brain. British journal of pharmacology. vol 64. issue 3. 1979-02-12. PMID:719232. |
the results suggest either a release of dopamine and noradrenaline by 5-hydroxytryptamine, with a compensatory increase in their synthesis, or an increase in the firing of dopaminergic and noradrenergic neurones after l-tryptophan. |
1979-02-12 |
2023-08-11 |
rat |
| L Edvinsson, J E Hardebo, J McCulloch, C Owma. Effects of dopaminergic agonists and antagonists on isolated cerebral blood vessels. Acta physiologica Scandinavica. vol 104. issue 3. 1979-01-26. PMID:716985. |
the vasomotor response of dopamine and dopaminergic agonists was studied in vitro on middle cerebral arteries from cat and pial arteries from humans. |
1979-01-26 |
2023-08-11 |
cat |
| F M Sharabi, J P Long, J G Canno. Hypotensive effect induced by a cyclic dopamine analog, trans-4-methyl-7,8-dihydroxy-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline. Journal of pharmaceutical sciences. vol 67. issue 11. 1979-01-24. PMID:712612. |
this study confirmed the possibility that the decrease in blood pressure and heart rate elicited by the dopamine analog is attributable to an effect on specific dopaminergic receptors. |
1979-01-24 |
2023-08-11 |
rat |
| J C Reubi, P C Emson, T M Jessell, L L Iverse. Effects of GABA, dopamine, and substance P on the release of newly synthesized 3H-5-hydroxytryptamine from rat substantia nigra in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 304. issue 3. 1979-01-24. PMID:714184. |
this effect seems to be indirect and is possibly mediated by dopaminergic neurones, since the dopamine antagonist drug alpha-flupenthixol (1 micron) abolished the substance p-evoked release of 5-ht. |
1979-01-24 |
2023-08-11 |
rat |
| J C Reubi, P C Emson, T M Jessell, L L Iverse. Effects of GABA, dopamine, and substance P on the release of newly synthesized 3H-5-hydroxytryptamine from rat substantia nigra in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 304. issue 3. 1979-01-24. PMID:714184. |
substance p may, therefore, activate nigral dopaminergic neurones which then release dopamine from their dendrites. |
1979-01-24 |
2023-08-11 |
rat |
| N White, Z Brown, M Yachni. Effects of catecholamine manipulations on three different self-stimulation behaviors. Pharmacology, biochemistry, and behavior. vol 9. issue 3. 1979-01-15. PMID:714976. |
at low doses of pimozide (a dopaminergic blocker) or of fla-57 (a dopamine beta-hydroxylase inhibitor) different effects on rates of responding were observed on each of the 3 tasks at the 2 electrode placements, indicating that the rate reductions were not the results of specific performance effects of the drugs. |
1979-01-15 |
2023-08-11 |
rat |
| P E Setler, H M Sarau, C L Zirkle, H L Saunder. The central effects of a novel dopamine agonist. European journal of pharmacology. vol 50. issue 4. 1978-12-27. PMID:568069. |
a new peripheral dopamine agonist which causes dopaminergic renal vasodilation, was tested for central dopaminergic activity. |
1978-12-27 |
2023-08-11 |
rat |
| B Bioulac, F Fumoux, A Ferron, J D Vincen. Responses of central neurones to piribedil and 2-bromo-alpha-ergocryptine: comparison with dopamine and apomorphine. European journal of pharmacology. vol 51. issue 1. 1978-12-27. PMID:699972. |
their effects were compared with those of dopamine and apomorphine on neurones of the frontal cortex and of the caudate nucleus both of which are rich in dopaminergic terminals. |
1978-12-27 |
2023-08-11 |
Not clear |