| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Langer, E J Sachar, R S Nathan, M A Tabrizi, J M Perel, F S Halper. Dopaminergic factors in human prolactin regulation: a pituitary model for the study of a neuroendocrine system in man. Psychopharmacology. vol 65. issue 2. 1980-02-15. PMID:117485. |
a dose of dopamine in the order of 15-60 microgram/min appeared to match the "loss" of endogenous dopaminergic inhibition due to the antidopaminergic effect of the neuroleptic drug. |
1980-02-15 |
2023-08-11 |
human |
| S Bischoff, B Scatton, J Kor. Dopamine metabolism, spiperone binding and adenylate cyclase activity in the adult rat hippocampus after ingrowth of dopaminergic neurones from embryonic implants. Brain research. vol 179. issue 1. 1980-02-15. PMID:509234. |
dopamine metabolism, spiperone binding and adenylate cyclase activity in the adult rat hippocampus after ingrowth of dopaminergic neurones from embryonic implants. |
1980-02-15 |
2023-08-11 |
rat |
| L L Brown, M H Markman, L I Wolfson, B Dvorkin, C Warner, R Katzma. A direct role of dopamine in the rat subthalamic nucleus and an adjacent intrapeduncular area. Science (New York, N.Y.). vol 206. issue 4425. 1980-01-28. PMID:505015. |
thus, neuronal function in this region is directly affected by dopamine and dopaminergic drugs. |
1980-01-28 |
2023-08-11 |
rat |
| S Dessaigne, A M Scotto, M Guigue. [Lithium modifications of the cataleptogenic properties of various neuroleptic drugs in the rat]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 172. issue 6. 1980-01-24. PMID:40676. |
licl would interfere at enzymatic level with dopaminergic transmission either by inhibiting activity of cerebral adenylcyclase (unique injection) or by inhibiting dopamine synthesis (repeated injections). |
1980-01-24 |
2023-08-11 |
rat |
| J Vardi, S Flechter, Z Oberman, M Allelov, J M Rabey, M Hertzberg, M Streifle. Plasma dopamine beta hydroxylase (D.B.H.) activity in Parkinsonian patients under L-dopa, and 2-bromo-alpha-ergocriptine loading. Journal of neural transmission. vol 46. issue 1. 1980-01-24. PMID:501350. |
the reduced d.b.h.-activity after treatment with 2-bromo-alpha-ergocriptine may be explained by a pronounced antagonistic influence of 2-bromo-alpha-ergocriptine on the presynaptic dopamine receptors, suggesting that presynaptic dopaminergic receptors are involved in parkinson's disease. |
1980-01-24 |
2023-08-11 |
Not clear |
| G Magelund, J Gerlach, D E Case. Neuroleptic-potentiating effect of alpha-methyl-p-tyrosine compared with haloperidol and placebo in a double-blind cross-over trial. Acta psychiatrica Scandinavica. vol 60. issue 2. 1980-01-19. PMID:41413. |
the hypothesis that schizophrenia results from overactive dopaminergic influences suggests that reducing dopamine synthesis may increase the clinical effects of dopamine receptor blocking neuroleptic drugs. |
1980-01-19 |
2023-08-11 |
Not clear |
| J McCulloch, H E Savaki, M C McCulloch, L Sokolof. Specific distribution of metabolic alterations in cerebral cortex following apomorphine administration. Nature. vol 282. issue 5736. 1980-01-19. PMID:503202. |
moreover, biochemical examinations of processes generally considered to be indicative of dopaminergic neuro-transmission--neuronal uptake of labelled dopamine or dopamine-activation of adenylate cyclase activity--have confirmed a highly restricted locus of action of dopaminergic systems in the cerebral cortex. |
1980-01-19 |
2023-08-11 |
rat |
| M Palkovits, L Záborszky, M J Brownstein, M I Fekete, J P Herman, B Kanyicsk. Distribution of norepinephrine and dopamine in cerebral cortical areas of the rat. Brain research bulletin. vol 4. issue 5. 1979-12-29. PMID:487214. |
the highest dopamine concentration (2,4 ng/mg protein) was measured in the rostral pyriform cortex but other mesocortical (cingulate, frontal, insular and entorhinal) dopaminergic areas also contained relatively high amounts. |
1979-12-29 |
2023-08-11 |
rat |
| F Peillon, F Cesselin, D Bression, N Zygelman, A M Brandi, A Nousbaum, A Mauborgn. In vitro effect of dopamine and L-dopa on prolactin and growth hormone release from human pituitary adenomas. The Journal of clinical endocrinology and metabolism. vol 49. issue 5. 1979-12-29. PMID:489713. |
to determine the site of action of dopaminergic drugs on human prl and gh release from pituitary adenomas, five prl-and five gh-secreting adenomas were incubated with and without dopamine and l-dopa. |
1979-12-29 |
2023-08-11 |
human |
| F Peillon, F Cesselin, D Bression, N Zygelman, A M Brandi, A Nousbaum, A Mauborgn. In vitro effect of dopamine and L-dopa on prolactin and growth hormone release from human pituitary adenomas. The Journal of clinical endocrinology and metabolism. vol 49. issue 5. 1979-12-29. PMID:489713. |
3) the paradoxical effect of dopaminergic drugs on gh secretion in acromegalic patients may be attributed to modified dopamine membrane receptors. |
1979-12-29 |
2023-08-11 |
human |
| G U Corsini, M Del Zompo, M P Piccardi, A Mangoni, G L Gess. Apomorphine as a preferential stimulant of self-inhibitory dopamine receptors in man. Annali dell'Istituto superiore di sanita. vol 14. issue 1. 1979-12-29. PMID:756167. |
these responses therefore are mediated through a stimulation of dopamine receptors leading to a decreased dopaminergic transmission. |
1979-12-29 |
2023-08-11 |
Not clear |
| P W Erhardt, R J Gorczynski, W G Anderso. Conformational analogues of dopamine. Synthesis and pharmacological activity of (E)- and (Z)-2-(3,4-dihydroxyphenyl)cyclopropylamine hydrochlorides. Journal of medicinal chemistry. vol 22. issue 8. 1979-12-18. PMID:40027. |
although neither of the compounds possessed dopaminergic activity in the canine renal blood-flow model, both agents were weak alpha-adrenergic agonists and exhibited cardiostimulatory properties similar to dopamine. |
1979-12-18 |
2023-08-11 |
Not clear |
| P M Laduron, J E Leyse. Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity. Biochemical pharmacology. vol 28. issue 14. 1979-12-18. PMID:496998. |
domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity. |
1979-12-18 |
2023-08-11 |
Not clear |
| J Costenti. [Modulation of dopaminergic receptor sensitivity in the central nervous system: important parameters in synaptic function regulation]. L'Encephale. vol 5. issue 2. 1979-11-28. PMID:38958. |
three main types differing by their behavioural and biochemical characteristics are described: -- disuse hypersensitivity to dopamine agonists, induced by an interruption of dopaminergic transmission, seems to depend on an increased number of post-synaptic dopamine receptors; -- hyposensitivity to dopamine agonists, induced by an overstimulation of dopamine receptors, could depend on their qualitative or quantitative modifications; -- behavioural facilitation, elicited by a previous administration of dopaminergic agonists in low dosage, could be associated with an hyposensitivity of dopaminergic autoreceptors. |
1979-11-28 |
2023-08-11 |
Not clear |
| C Chevillard, M N Mathie. Mechanism of the depressor response to dopamine in the rat treated with phenoxybenzamine. European journal of pharmacology. vol 56. issue 4. 1979-11-28. PMID:477731. |
the data suggest that in rats the depressor component of dopamine is due to activation of both dopaminergic and beta-adrenoceptors. |
1979-11-28 |
2023-08-11 |
rat |
| L R Skirboll, A A Grace, B S Bunne. Dopamine auto- and postsynaptic receptors: electrophysiological evidence for differential sensitivity to dopamine agonists. Science (New York, N.Y.). vol 206. issue 4414. 1979-11-21. PMID:482929. |
dopaminergic cells were six to ten times more sensitive to dopamine and intravenous apomorphine than 86 percent of the caudate cells tested. |
1979-11-21 |
2023-08-11 |
Not clear |
| L R Skirboll, A A Grace, B S Bunne. Dopamine auto- and postsynaptic receptors: electrophysiological evidence for differential sensitivity to dopamine agonists. Science (New York, N.Y.). vol 206. issue 4414. 1979-11-21. PMID:482929. |
this differential sensitivity of dopamine auto- and postsynaptic receptors may explain the apparently paradoxical behavioral effects induced by small compared to large doses of some dopamine agonists and may provide a means of developing new types of drugs to antagonize dopaminergic influence in the central nervous system. |
1979-11-21 |
2023-08-11 |
Not clear |
| P D Woolf, R Lantigua, L A Le. Dopamine inhibition of stimulated growth hormone secretion: evidence for dopaminergic modulation of insulin- and L-dopa-induced growth hormone secretion in man. The Journal of clinical endocrinology and metabolism. vol 49. issue 3. 1979-10-26. PMID:468965. |
dopamine inhibition of stimulated growth hormone secretion: evidence for dopaminergic modulation of insulin- and l-dopa-induced growth hormone secretion in man. |
1979-10-26 |
2023-08-11 |
Not clear |
| G Lelord, E Callaway, J P Muh, J C Arlot, D Sauvage, B Garreau, J Domenec. [Modifications in urinary homovanillic acid after ingestion of vitamin B6; functional study in autistic children (author's transl)]. Revue neurologique. vol 134. issue 12. 1979-10-26. PMID:754238. |
basing their study on the investigations which led to the dopaminergic theory of the psychoses, the authors studied homovanillic acid (principal derivative from dopamine) levels in the urines of 37 autistic children, and 11 normal children acting as controls. |
1979-10-26 |
2023-08-11 |
Not clear |
| T L O'Donohue, W R Crowley, D M Jacobowit. Biochemical mapping of the noradrenergic ventral bundle projection sites: evidence for a noradrenergic--dopaminergic interaction. Brain research. vol 172. issue 1. 1979-10-24. PMID:466469. |
norepinephrine (ne) and dopamine (da) concentration and dopamine turnover were measured 12 days after a unilateral or bilateral noradrenergic ventral bundle (vb) transection to determine the noradrenergic projection sites and possible interactions with dopaminergic systems. |
1979-10-24 |
2023-08-11 |
Not clear |