| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B W Caprathe, J C Jaen, L D Wise, T G Heffner, T A Pugsley, L T Meltzer, M Parve. Dopamine autoreceptor agonists as potential antipsychotics. 3.6-Propyl-4,5,5a,6,7,8-hexahydrothiazolo[4,5-f]quinolin-2-amine. Journal of medicinal chemistry. vol 34. issue 9. 1991-10-22. PMID:1680195. |
a series of rigid tricyclic analogues of the dopamine (da) agonist pd 118440 [4-(1,2,5,6-tetrahydro-1-propyl-3-pyridinyl)-2-thiazolamine] was synthesized and evaluated for dopaminergic activity and da autoreceptor selectivity. |
1991-10-22 |
2023-08-11 |
rat |
| M Diana, S J Young, P M Grove. Modulation of dopaminergic terminal excitability by D1 selective agents: further characterization. Neuroscience. vol 42. issue 2. 1991-10-21. PMID:1680226. |
striatal application of the active r-(+) enantiomer of the dopaminergic d1-selective agonist 1-phenyl-2,3,4,5-tetrahydrol-(1h)-3-benzazepine-7,8-diol-hcl (r-skf 38393) decreases terminal excitability in the alpha-methyl-paratyrosine pretreated animal, indicating that dopamine is not required for the agonist action. |
1991-10-21 |
2023-08-11 |
rat |
| I A Paterson, A V Juorio, M D Berry, M Y Zh. Inhibition of monoamine oxidase-B by (-)-deprenyl potentiates neuronal responses to dopamine agonists but does not inhibit dopamine catabolism in the rat striatum. The Journal of pharmacology and experimental therapeutics. vol 258. issue 3. 1991-10-17. PMID:1679846. |
this report describes experiments designed to determine whether (-)-deprenyl potentiates dopaminergic transmission and whether its mechanism involves the inhibition of dopamine catabolism. |
1991-10-17 |
2023-08-11 |
rat |
| S Levi-Minzi, P C Bermanzohn, S G Siri. Bromocriptine for "negative" schizophrenia. Comprehensive psychiatry. vol 32. issue 3. 1991-10-07. PMID:1679383. |
the hypothesis that the pathophysiology of negative symptoms in schizophrenia may involve relative hypoactivity of central dopaminergic neurotransmission prompts the exploration of dopamine agonist strategies in the treatment of this condition. |
1991-10-07 |
2023-08-11 |
Not clear |
| G L Bernardini, X Gu, E Viscardi, D C Germa. Amphetamine-induced and spontaneous release of dopamine from A9 and A10 cell dendrites: an in vitro electrophysiological study in the mouse. Journal of neural transmission. General section. vol 84. issue 3. 1991-10-04. PMID:1679335. |
d-amphetamine (d-amp) is a potent releaser of dopamine (da), and its central nervous system stimulant action is mediated primarily through its effect on the substantia nigra and ventral tegmental area dopaminergic neurons (nuclei a9 and a10, respectively). |
1991-10-04 |
2023-08-11 |
mouse |
| M Kujacic, K Svensson, L Löfberg, A Carlsso. Dopamine receptors, controlling dopamine levels in rat adrenal glands-comparison with central dopaminergic autoreceptors. Journal of neural transmission. General section. vol 84. issue 3. 1991-10-04. PMID:1679336. |
dopamine receptors, controlling dopamine levels in rat adrenal glands-comparison with central dopaminergic autoreceptors. |
1991-10-04 |
2023-08-11 |
rat |
| Y Ishida, H Hashiguchi, R Yamamoto, T Hashitani, T Ikeda, H Nishin. Effect of intra-amygdala dopaminergic grafts on methamphetamine-induced locomotor activity, extracellular dopamine and dopamine metabolite overflow: a comparison with the effect of intra-accumbens grafts. Brain research. vol 549. issue 2. 1991-10-04. PMID:1909206. |
effect of intra-amygdala dopaminergic grafts on methamphetamine-induced locomotor activity, extracellular dopamine and dopamine metabolite overflow: a comparison with the effect of intra-accumbens grafts. |
1991-10-04 |
2023-08-11 |
rat |
| G Pelletier, J Simar. Dopaminergic regulation of pre-proNPY mRNA levels in the rat arcuate nucleus. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1679226. |
in order to study the role of dopamine on neuropeptide y (npy) gene expression in the rat arcuate nucleus, we evaluated the effects of haloperidol, a dopaminergic antagonist, and bromocriptine, a d2 dopamine receptor agonist, on the levels of pre-pronpy mrna as measured by in situ hybridization. |
1991-09-30 |
2023-08-11 |
rat |
| Z S Herman, M Huzarska, K Kmieciak-Kolada, J Kowalsk. Chronic treatment with chlorpromazine, thioridazine or haloperidol increases striatal enkephalins and their release from rat brain. Psychopharmacology. vol 104. issue 1. 1991-09-30. PMID:1881995. |
it is concluded that: 1) chronic administration of neuroleptic drugs that block dopamine receptors increases the level and the release of striatal enkephalins; 2) the results support the hypothesis that activation of dopaminergic neurons tonically inhibits the synthesis of enkephalins in the striatum. |
1991-09-30 |
2023-08-11 |
rat |
| Y Bacq, C Gaudin, A Hadengue, D Roulot, A Braillon, R Moreau, D Lebre. Systemic, splanchnic and renal hemodynamic effects of a dopaminergic dose of dopamine in patients with cirrhosis. Hepatology (Baltimore, Md.). vol 14. issue 3. 1991-09-26. PMID:1874493. |
systemic, splanchnic and renal hemodynamic effects of a dopaminergic dose of dopamine in patients with cirrhosis. |
1991-09-26 |
2023-08-11 |
Not clear |
| Y Bacq, C Gaudin, A Hadengue, D Roulot, A Braillon, R Moreau, D Lebre. Systemic, splanchnic and renal hemodynamic effects of a dopaminergic dose of dopamine in patients with cirrhosis. Hepatology (Baltimore, Md.). vol 14. issue 3. 1991-09-26. PMID:1874493. |
thus we studied the acute systemic, splanchnic and renal hemodynamic effects of a dopaminergic dose of dopamine (1.5 micrograms/kg body wt min) in nine cirrhotic patients. |
1991-09-26 |
2023-08-11 |
Not clear |
| Y Bacq, C Gaudin, A Hadengue, D Roulot, A Braillon, R Moreau, D Lebre. Systemic, splanchnic and renal hemodynamic effects of a dopaminergic dose of dopamine in patients with cirrhosis. Hepatology (Baltimore, Md.). vol 14. issue 3. 1991-09-26. PMID:1874493. |
we conclude that a dopaminergic dose of dopamine increases azygos blood flow but not the hepatic venous pressure gradient. |
1991-09-26 |
2023-08-11 |
Not clear |
| O Giorgi, M G Pibiri, E Ongini, M Trampus, G Biggi. The neutral endopeptidase-24.11 (enkephalinase) inhibitor, SCH 32615, increases dopamine metabolism in the nucleus accumbens of the rat. European journal of pharmacology. vol 196. issue 2. 1991-09-20. PMID:1874283. |
the present study was designed to assess whether sch 32615 is able to modify the activity of dopaminergic neurons as reflected by changes in the content of the major dopamine metabolite, dihydroxyphenylacetic acid (dopac), in three different areas of the rat brain: the nucleus accumbens, the striatum, and the prefrontal cortex. |
1991-09-20 |
2023-08-11 |
rat |
| P Aebischer, S R Winn, P A Tresco, C B Jaeger, L A Green. Transplantation of polymer encapsulated neurotransmitter secreting cells: effect of the encapsulation technique. Journal of biomechanical engineering. vol 113. issue 2. 1991-09-20. PMID:1875690. |
in the present study, we compared the ability of dopamine-secreting cells, encapsulated by 2 different methods, to reverse experimental parkinson's disease, a neurodegenerative disease characterized by motor disturbances due to a lack of dopamine within the striatum following degeneration of the dopaminergic nigro-striatal pathway. |
1991-09-20 |
2023-08-11 |
rat |
| J Den. [Effect of dopamine and bromocriptine on secretion of growth hormone by pituitary growth hormone secreting tumor in cell culture]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 12. issue 5. 1991-09-20. PMID:1966332. |
this article reports the effect of dopamine (da) and its agonist bromocriptine (cb154) on the secretion of growth hormone (gh) by pure gh-secreting pituitary tumor in cell culture as well as a comparison of the effects of these dopaminergic drugs and sms201-295 (sms). |
1991-09-20 |
2023-08-11 |
Not clear |
| K M Guthrie, J M Pullara, J F Marshall, M Leo. Olfactory deprivation increases dopamine D2 receptor density in the rat olfactory bulb. Synapse (New York, N.Y.). vol 8. issue 1. 1991-09-16. PMID:1831300. |
we describe here the effects of early olfactory deprivation on other elements of the bulb dopaminergic system, namely the dopamine receptors of the olfactory bulb. |
1991-09-16 |
2023-08-11 |
rat |
| T Huo, D P Heal. [3H]domperidone binding to the kidney inner medullary collecting duct dopamine-2K (DA2K) receptor. The Journal of pharmacology and experimental therapeutics. vol 258. issue 2. 1991-09-11. PMID:1830902. |
dopaminergic drugs were less potent competitors for [3h]domperidone binding in imcd cells than previously reported for brain da receptors, but the rank order was consistent with the labeling of a da receptor [antagonists: domperidone greater than spiperone greater than haloperidol greater than sch 23390 much greater than (-)-sulpiride; agonists: norapomorphine greater than fenoldopam much greater than dopamine = quinpirole], and was better correlated with the pharmacological profile for the brain d2 receptor than the brain d3 receptor. |
1991-09-11 |
2023-08-11 |
Not clear |
| C Fernicola, S Govoni, L Coniglio, E Daniele, M Trabucch. [The use of 1,1,1-trichloroethane (methylchloroform) in industrial operations: the neurotoxicity risk]. La Medicina del lavoro. vol 82. issue 1. 1991-09-11. PMID:1865846. |
it has been also suggested that intermediate metabolites of 1,1,1-te may give origin to condensation products with dopamine, ultimately impairing dopaminergic transmission. |
1991-09-11 |
2023-08-11 |
mouse |
| T Momiyama, M Sasa, S Takaor. Inhibition by talipexole, a thiazolo-azepine derivative, of dopaminergic neurons in the ventral tegmental area. Life sciences. vol 49. issue 7. 1991-09-05. PMID:1677740. |
a microiontophoretic study using rats anesthetized with chloral hydrate and immobilized with gallamine triethiodide was carried out to compare the effect of talipexole (b-ht 920 cl2:2-amino-6-allyl-5,6,7,8-tetrahydro-4h-thiazolo [4,5-d]-azepine-dihydrochloride), a dopamine autoreceptor agonist, on dopaminergic neurons in the ventral tegmental area (vta) to non-dopaminergic neurons in the vta. |
1991-09-05 |
2023-08-11 |
rat |
| T Momiyama, M Sasa, S Takaor. Inhibition by talipexole, a thiazolo-azepine derivative, of dopaminergic neurons in the ventral tegmental area. Life sciences. vol 49. issue 7. 1991-09-05. PMID:1677740. |
these results suggest that talipexole acts on dopamine d-2 receptors, thereby inhibiting the dopaminergic neurons in the vta. |
1991-09-05 |
2023-08-11 |
rat |