| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Kuhar, M C Ritz, J W Boj. The dopamine hypothesis of the reinforcing properties of cocaine. Trends in neurosciences. vol 14. issue 7. 1991-12-02. PMID:1719677. |
this hypothesis proposes that cocaine binds at the dopamine transporter and mainly inhibits neurotransmitter re-uptake; the resulting potentiation of dopaminergic neurotransmission in mesolimbocortical pathways ultimately causes reinforcement. |
1991-12-02 |
2023-08-11 |
Not clear |
| H Sershen, A Hashim, L Harsing, A Lajth. Chronic nicotine-induced changes in dopaminergic system: effect on behavioral response to dopamine agonist. Pharmacology, biochemistry, and behavior. vol 39. issue 2. 1991-11-26. PMID:1682953. |
chronic nicotine-induced changes in dopaminergic system: effect on behavioral response to dopamine agonist. |
1991-11-26 |
2023-08-11 |
mouse |
| H Sershen, A Hashim, L Harsing, A Lajth. Chronic nicotine-induced changes in dopaminergic system: effect on behavioral response to dopamine agonist. Pharmacology, biochemistry, and behavior. vol 39. issue 2. 1991-11-26. PMID:1682953. |
the results suggest that chronic nicotine may induce changes in the dopaminergic system, which is reflected in altered behavioral response to a dopamine agonist. |
1991-11-26 |
2023-08-11 |
mouse |
| F De Vitry, J Hillion, J Catelon, J Thibault, J J Benoliel, M Hamo. Dopamine increases the expression of tyrosine hydroxylase and aromatic amino acid decarboxylase in primary cultures of fetal neurons. Brain research. Developmental brain research. vol 59. issue 2. 1991-11-18. PMID:1680579. |
furthermore, apomorphine treatment also decreased the levels of cholecystokinin-like material in primary cultures from the brainstem (but not the hypothalamus) where both dopamine and cholecystokinin are--partly--colocalized in mesencephalic dopaminergic neurons. |
1991-11-18 |
2023-08-11 |
mouse |
| M F O'Neill, C T Dourish, S D Iverse. Evidence for an involvement of D1 and D2 dopamine receptors in mediating nicotine-induced hyperactivity in rats. Psychopharmacology. vol 104. issue 3. 1991-11-18. PMID:1833784. |
the effect appears to be mediated by central nicotine receptors, possibly located on dopaminergic neurons, and also requires the activation of both d1 and d2 dopamine receptors. |
1991-11-18 |
2023-08-11 |
rat |
| G al-Tajir, M S Star. Anticonvulsant effect of striatal dopamine D2 receptor stimulation: dependence on cortical circuits? Neuroscience. vol 43. issue 1. 1991-11-15. PMID:1681459. |
to explain these findings, an interplay between nigrostriatal dopaminergic and corticostriatal glutamatergic neurons is proposed, in which the anticonvulsant tendency of the excitatory amino acid is accentuated by dopamine, probably by acting on d2 receptors which facilitate the release of glutamate from axon terminals. |
1991-11-15 |
2023-08-11 |
rat |
| T Nagase, K Hotta, S Morita, K Sakai, M Yamane, M Omote, H Mizusaw. [Pharmacological effects of the novel dopamine uptake inhibitor 1-[2-[bis(4-fluorophenyl)-methoxy]ethyl]-4-(3-phenylpropyl) piperazine dihydrochloride (I-893) on the central nervous system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 98. issue 2. 1991-11-13. PMID:1833294. |
these results suggest that i-893 inhibits re-uptake of dopamine released by exocytosis and indirectly has dopaminergic effects. |
1991-11-13 |
2023-08-11 |
mouse |
| S Retaux, M J Besson, J Penit-Sori. Synergism between D1 and D2 dopamine receptors in the inhibition of the evoked release of [3H]GABA in the rat prefrontal cortex. Neuroscience. vol 43. issue 2-3. 1991-11-13. PMID:1833669. |
in order to examine a possible interaction between d1 and d2 receptors in the dopaminergic control of the electrically-evoked release of [3h]gaba in the rat prefrontal cortex, the effects of d1 and d2 dopamine agonists were studied in vitro on cortical slices. |
1991-11-13 |
2023-08-11 |
rat |
| F C Liu, S B Dunnett, H A Robertson, A M Graybie. Intrastriatal grafts derived from fetal striatal primordia. III. Induction of modular patterns of fos-like immunoreactivity by cocaine. Experimental brain research. vol 85. issue 3. 1991-11-05. PMID:1680735. |
previous studies have shown that presynaptic and postsynaptic cellular markers of the dopaminergic system in the striatum, including immunostaining for th and dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein (darpp-32), and binding for high affinity dopamine uptake sites and for dopamine d1 and d2 receptor sites, are all concentrated in the ache-rich patch regions (p regions) of such embryonic striatal grafts. |
1991-11-05 |
2023-08-11 |
rat |
| C Beyer, C Pilgrim, I Reisert, U Misgel. Cells from embryonic rat striatum cocultured with mesencephalic glia express dopaminergic phenotypes. Neuroscience letters. vol 128. issue 1. 1991-11-05. PMID:1681474. |
by antityrosine hydroxylase immunocytochemistry, immunoblotting of tyrosine hydroxylase protein and quantitation of dopamine and its metabolites by hplc, dopaminergic cells were revealed in nigral and neostriatal cultures plated on nigral glial cells. |
1991-11-05 |
2023-08-11 |
rat |
| A Velardo, M Pantaleoni, C Zironi, G Zizzo, P Marram. Evidence of altered dopaminergic modulation of prolactin and thyrotropin secretion in patients with polycystic ovary syndrome. Hormone research. vol 35. issue 1. 1991-11-05. PMID:1916652. |
in order to evaluate the functional activity of the tubero-infundibular dopaminergic system in polycystic ovary syndrome (pcos), we analysed the prolactin (prl) and thyrotropin (tsh) responses to the dopamine antagonist sulpiride. |
1991-11-05 |
2023-08-11 |
human |
| W T O'Connor, N Lindefors, S Brené, M Herrera-Marschitz, H Persson, U Ungersted. Short-term dopaminergic regulation of GABA release in dopamine deafferented caudate-putamen is not directly associated with glutamic acid decarboxylase gene expression. Neuroscience letters. vol 128. issue 1. 1991-11-05. PMID:1922949. |
short-term dopaminergic regulation of gaba release in dopamine deafferented caudate-putamen is not directly associated with glutamic acid decarboxylase gene expression. |
1991-11-05 |
2023-08-11 |
rat |
| W T O'Connor, N Lindefors, S Brené, M Herrera-Marschitz, H Persson, U Ungersted. Short-term dopaminergic regulation of GABA release in dopamine deafferented caudate-putamen is not directly associated with glutamic acid decarboxylase gene expression. Neuroscience letters. vol 128. issue 1. 1991-11-05. PMID:1922949. |
these findings indicate that dopaminergic regulation of gaba neurons in the dopamine deafferented cpu includes both a short-term effect at the level of gaba release independent of changes in gad mrna expression and a long-term modulation at the level of gad gene expression. |
1991-11-05 |
2023-08-11 |
rat |
| T Hattori, M Takada, T Moriizumi, D Van der Koo. Single dopaminergic nigrostriatal neurons form two chemically distinct synaptic types: possible transmitter segregation within neurons. The Journal of comparative neurology. vol 309. issue 3. 1991-11-04. PMID:1717519. |
thus, we suggest that single dopaminergic neurons in the substantia nigra make two types of synaptic contact with striatal cells: 1) symmetric synapses en passant, which can be stained with tyrosine hydroxylase and dopamine and which contact dendritic spine necks, and 2) asymmetric terminal boutons of unknown chemical nature which end on dendritic spine heads. |
1991-11-04 |
2023-08-11 |
rat |
| W J Florijn, T De Boer, J A Tonnaer, J W Van Nispen, D H Verstee. ACTH/MSH-like peptides inhibit the binding of dopaminergic ligands to the dopamine D2 receptor in vitro. European journal of pharmacology. vol 207. issue 1. 1991-11-01. PMID:1680721. |
acth/msh-like peptides inhibit the binding of dopaminergic ligands to the dopamine d2 receptor in vitro. |
1991-11-01 |
2023-08-11 |
rat |
| W J Smeets, M N Kidjan, A J Jonke. Alpha-MPT does not affect dopamine levels in the periventricular organ of lizards. Neuroreport. vol 2. issue 7. 1991-10-30. PMID:1680484. |
subsequent staining with dopamine antiserum revealed almost no changes in staining in the periventricular organ but there was a dramatic decrease in the other dopaminergic cell groups of the brain. |
1991-10-30 |
2023-08-11 |
Not clear |
| P Stanzione, F Fattapposta, P Giunti, C D'Alessio, M Tagliati, C Affricano, G Amabil. P300 variations in parkinsonian patients before and during dopaminergic monotherapy: a suggested dopamine component in P300. Electroencephalography and clinical neurophysiology. vol 80. issue 5. 1991-10-24. PMID:1716570. |
p300 variations in parkinsonian patients before and during dopaminergic monotherapy: a suggested dopamine component in p300. |
1991-10-24 |
2023-08-11 |
human |
| D Prasher, L Findle. Dopaminergic induced changes in cognitive and motor processing in Parkinson's disease: an electrophysiological investigation. Journal of neurology, neurosurgery, and psychiatry. vol 54. issue 7. 1991-10-24. PMID:1895125. |
motor processing may reflect the dopamine status of the putamen whereas dopaminergic over-stimulation of other regions may adversely affect cognitive processing in patients treated with levodopa. |
1991-10-24 |
2023-08-11 |
Not clear |
| G W Lambert, G Eisenhofer, H S Cox, M Horne, V Kalff, M Kelly, G L Jennings, M D Esle. Direct determination of homovanillic acid release from the human brain, an indicator of central dopaminergic activity. Life sciences. vol 49. issue 15. 1991-10-24. PMID:1895870. |
the plasma concentration of the dopamine (da) metabolite, homovanillic acid (hva), is used as an indicator of central nervous system dopaminergic activity. |
1991-10-24 |
2023-08-11 |
human |
| F Rodriguez, T Joli. The role of somatostatin and/or dopamine in basal and TRH-stimulated TSH release in food-restricted rats. Acta endocrinologica. vol 125. issue 2. 1991-10-23. PMID:1680265. |
intravenous injections of the dopamine antagonists, domperidone or haloperidol, failed to affect the magnitude of the differences in plasma tsh and gh levels among control and food-restricted groups, indicating that dopaminergic mechanisms had little effect on the regulation of tsh and gh secretion during restricted feeding in rats. |
1991-10-23 |
2023-08-11 |
rat |