| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ginetta Collo, Federica Bono, Laura Cavalleri, Laura Plebani, Emilio Merlo Pich, Mark J Millan, Pier Franco Spano, Cristina Missal. Pre-synaptic dopamine D(3) receptor mediates cocaine-induced structural plasticity in mesencephalic dopaminergic neurons via ERK and Akt pathways. Journal of neurochemistry. vol 120. issue 5. 2012-04-05. PMID:22145570. |
pre-synaptic dopamine d(3) receptor mediates cocaine-induced structural plasticity in mesencephalic dopaminergic neurons via erk and akt pathways. |
2012-04-05 |
2023-08-12 |
mouse |
| Ginetta Collo, Federica Bono, Laura Cavalleri, Laura Plebani, Emilio Merlo Pich, Mark J Millan, Pier Franco Spano, Cristina Missal. Pre-synaptic dopamine D(3) receptor mediates cocaine-induced structural plasticity in mesencephalic dopaminergic neurons via ERK and Akt pathways. Journal of neurochemistry. vol 120. issue 5. 2012-04-05. PMID:22145570. |
increased dendrite arborization and soma area were previously observed in primary cultures of mesencephalic dopaminergic neurons after 3-day exposure to dopamine agonists via activation of d(3) autoreceptors (d(3) r). |
2012-04-05 |
2023-08-12 |
mouse |
| S A Strejilevich, J Teitelbaum, D J Martino, D Quiroz, F Kapczinsk. Dopamine sudden depletion as a model for mixed depression. Medical hypotheses. vol 78. issue 1. 2012-04-03. PMID:22036092. |
interestingly enough, other syndromes arising from sudden dopamine depletion such as neuroleptic dysphoria or withdrawal syndromes from dopaminergic drugs, bear remarkable clinical similarities with mixed depression. |
2012-04-03 |
2023-08-12 |
human |
| S A Strejilevich, J Teitelbaum, D J Martino, D Quiroz, F Kapczinsk. Dopamine sudden depletion as a model for mixed depression. Medical hypotheses. vol 78. issue 1. 2012-04-03. PMID:22036092. |
this hypothesis provides with a beginning step for the neglected problem of mixed depression, a non-antithetic link between the dopaminergic hypothesis for both manic and depressive symptoms, a plausible explanation regarding inter individual variability to mixed depression susceptibility, and suggests new approaches for the development of novel treatments in which dopamine dysregulation should be targeted. |
2012-04-03 |
2023-08-12 |
human |
| Marinete Pinheiro Carrera, Robert J Carey, Flávia Regina Cruz Dias, Liana Wermelinger de Mato. Reversal of apomorphine locomotor sensitization by a single post-conditioning trial treatment with a low autoreceptor dose of apomorphine: a memory re-consolidation approach. Pharmacology, biochemistry, and behavior. vol 99. issue 1. 2012-04-02. PMID:21447355. |
the activation of dopaminergic systems by the high dose of apomorphine strengthened the drug/environment association whereas the inhibition of dopamine activity by the low auto-receptor dose eliminated this association. |
2012-04-02 |
2023-08-12 |
Not clear |
| Seung-Nam Kim, Ah-Reum Doo, Ji-Yeun Park, Hyungjin Bae, Younbyoung Chae, Insop Shim, Hyangsook Lee, Woongjoon Moon, Hyejung Lee, Hi-Joon Par. Acupuncture enhances the synaptic dopamine availability to improve motor function in a mouse model of Parkinson's disease. PloS one. vol 6. issue 11. 2012-04-02. PMID:22132113. |
parkinson's disease (pd) is caused by the selective loss of dopaminergic neurons in the substantia nigra (sn) and the depletion of striatal dopamine (da). |
2012-04-02 |
2023-08-12 |
mouse |
| Hoa A Lam, Nanping Wu, Ingrid Cely, Rachel L Kelly, Sindalana Hean, Franziska Richter, Iddo Magen, Carlos Cepeda, Larry C Ackerson, Wendy Walwyn, Eliezer Masliah, Marie-Françoise Chesselet, Michael S Levine, Nigel T Maidmen. Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein. Journal of neuroscience research. vol 89. issue 7. 2012-03-29. PMID:21488084. |
we used in vivo microdialysis, tissue content analysis, behavioral assessment, and whole-cell patch clamp recordings from striatal medium-sized spiny neurons (mssns) in slices to examine dopamine transmission and dopaminergic modulation of corticostriatal synaptic function in mice overexpressing human wild-type α-syn under the thy1 promoter (α-syn mice). |
2012-03-29 |
2023-08-12 |
mouse |
| Esteban Muñoz, Alex Iranzo, Sebastian Rauek, Francisco Lomeña, Judith Gallego, Doménec Ros, Joan Santamaría, Eduardo Tolos. Subclinical nigrostriatal dopaminergic denervation in the cerebellar subtype of multiple system atrophy (MSA-C). Journal of neurology. vol 258. issue 12. 2012-03-28. PMID:21633903. |
our objective was to assess nigrostriatal dopaminergic innervation in patients with msa-c without parkinsonism by use of dopamine transporter single photon emission computed tomography (dat spect). |
2012-03-28 |
2023-08-12 |
Not clear |
| Hirofumi Tokuoka, Shin-ichi Muramatsu, Chiho Sumi-Ichinose, Hiroaki Sakane, Masayo Kojima, Yoshinori Aso, Takahide Nomura, Daniel Metzger, Hiroshi Ichinos. Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection. The Journal of biological chemistry. vol 286. issue 50. 2012-03-27. PMID:22027820. |
the tyrosine hydroxylase (th; ec 1.14.16.2) is a rate-limiting enzyme in the dopamine synthesis and important for the central dopaminergic system, which controls voluntary movements and reward-dependent behaviors. |
2012-03-27 |
2023-08-12 |
mouse |
| Susanne Nikolaus, Rolf Larisch, Henning Vosberg, Markus Beu, Andreas Wirrwar, Christina Antke, Konstantin Kley, Maria Angelica De Souza Silva, Joseph P Huston, Hans-Wilhelm Mülle. Pharmacological challenge and synaptic response - assessing dopaminergic function in the rat striatum with small animal single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Reviews in the neurosciences. vol 22. issue 6. 2012-03-27. PMID:22103308. |
disturbances of dopaminergic neurotransmission may be caused by changes in concentrations of synaptic dopamine (da) and/or availabilities of pre- and post-synaptic transporter and receptor binding sites. |
2012-03-27 |
2023-08-12 |
rat |
| Fabrizio Stocch. Continuous dopaminergic stimulation and novel formulations of dopamine agonists. Journal of neurology. vol 258. issue Suppl 2. 2012-03-25. PMID:21560062. |
continuous dopaminergic stimulation and novel formulations of dopamine agonists. |
2012-03-25 |
2023-08-12 |
Not clear |
| Fabrizio Stocch. Continuous dopaminergic stimulation and novel formulations of dopamine agonists. Journal of neurology. vol 258. issue Suppl 2. 2012-03-25. PMID:21560062. |
there is now accumulating evidence that the combination of progressive pathology of parkinson's disease, the change in drug pharmacodynamics, and the pulsatile manner in which short-acting dopaminergic agents stimulate striatal dopamine receptors are the key contributing factors to the priming of the basal ganglia for induction of motor complications. |
2012-03-25 |
2023-08-12 |
Not clear |
| D Domenger, D Dea, L Theroux, L Moquin, A Gratton, J Poirie. The MPTP neurotoxic lesion model of Parkinson's disease activates the apolipoprotein E cascade in the mouse brain. Experimental neurology. vol 233. issue 1. 2012-03-25. PMID:22155743. |
in the striatum, upregulations of gfap, apoe and lrp mrnas at 1 day post-treatment were associated with marked decreases in dopamine (da) levels, loss in tyrosine hydroxylase protein content, as well as to a compensatory increase in dopaminergic metabolism. |
2012-03-25 |
2023-08-12 |
mouse |
| Elena Choleris, Amy E Clipperton-Allen, Durene G Gray, Sebastian Diaz-Gonzalez, Robert G Welsma. Differential effects of dopamine receptor D1-type and D2-type antagonists and phase of the estrous cycle on social learning of food preferences, feeding, and social interactions in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 8. 2012-03-22. PMID:21525863. |
we examined the involvement of the dopaminergic system in social learning by administering a dopamine d1-type receptor antagonist, sch23390 (0.01, 0.05, and 0.1 mg/kg), or a d2-type receptor antagonist, raclopride (0.1, 0.3, and 0.6 mg/kg), to adult female mice prior to socially learning a food preference. |
2012-03-22 |
2023-08-12 |
mouse |
| J A Goldberg, H Bergma. Computational physiology of the neural networks of the primate globus pallidus: function and dysfunction. Neuroscience. vol 198. 2012-03-22. PMID:21925240. |
finally, degeneration of midbrain dopaminergic neurons and striatal dopamine depletion (as in parkinson's disease) lead to augmentation of striatal excitability and competitive dynamics. |
2012-03-22 |
2023-08-12 |
Not clear |
| Chiara Milanese, Jonathan J Sager, Qing Bai, Thomas C Farrell, Jason R Cannon, J Timothy Greenamyre, Edward A Burto. Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins. The Journal of biological chemistry. vol 287. issue 5. 2012-03-22. PMID:22128150. |
zebrafish lacking both β- and γ1-synucleins were more severely hypokinetic than animals lacking one or the other synuclein and showed delayed differentiation of dopaminergic neurons and reduced dopamine levels. |
2012-03-22 |
2023-08-12 |
human |
| Dorothée Lulé, Johanna Heimrath, Elmar H Pinkhardt, Albert C Ludolph, Ingo Uttner, Jan Kassube. Deep brain stimulation and behavioural changes: is comedication the most important factor? Neuro-degenerative diseases. vol 9. issue 1. 2012-03-20. PMID:21778695. |
adverse effects of dopaminergic medication (da; levodopa and dopamine agonists) on impulsive behaviour and decision-making in patients with parkinson's disease (pd) have been repeatedly reported. |
2012-03-20 |
2023-08-12 |
Not clear |
| Ned Jenkinson, Peter Brow. New insights into the relationship between dopamine, beta oscillations and motor function. Trends in neurosciences. vol 34. issue 12. 2012-03-15. PMID:22018805. |
loss of dopamine, as in parkinson's disease, annuls this function, unless net dopaminergic activity can be elevated through medication. |
2012-03-15 |
2023-08-12 |
human |
| Shawn J Kil. Neuropsychiatric update: neuroimaging schizophrenia. Psychopharmacology bulletin. vol 40. issue 4. 2012-03-13. PMID:18227785. |
neurochemical imaging studies of schizophrenia are reviewed and noted to support dopaminergic dysregulation consistent with the dopamine hypothesis. |
2012-03-13 |
2023-08-12 |
Not clear |
| David E Vaillancourt, Matthew B Spraker, Janey Prodoehl, Xiaohong Joe Zhou, Deborah M Littl. Effects of aging on the ventral and dorsal substantia nigra using diffusion tensor imaging. Neurobiology of aging. vol 33. issue 1. 2012-03-13. PMID:20359780. |
dopaminergic neurons in the substantia nigra produce dopamine for the nigrostriatal pathway that facilitates motor function. |
2012-03-13 |
2023-08-12 |
Not clear |