Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
N Hayase, K Tomiyoshi, K Watanabe, S Horikoshi, T Shibasaki, C Ohy. Positron emission tomography with 4-[18F]fluoro-L-m-tyrosine in MPTP-induced hemiparkinsonian monkeys. Annals of nuclear medicine. vol 9. issue 3. 1996-02-05. PMID:8534583. |
fmt-pet studies were able to detect dopaminergic terminals in both normal and hemiparkinsonian monkeys, and clearly showed a reduction in aromatic l-amino acid decarboxylase (aaad) activities in the mptp-lesioned striatum. |
1996-02-05 |
2023-08-12 |
monkey |
M O Kreb. [Glutamatergic hypothesis of schizophrenia: psychoses induced by phencyclidine and cortical-subcortical imbalance]. L'Encephale. vol 21. issue 5. 1996-01-29. PMID:8529568. |
positive symptoms could also be due to a secondary hyperdopaminergia, since a part of striatum, the striosomes, connected with limbic system, control the activity of dopaminergic neurons. |
1996-01-29 |
2023-08-12 |
human |
P Remy, H Hosseini, J D Degos, Y Samson, Y Agid, J M Warter, M Vidailhe. Striatal dopaminergic denervation in pallidopyramidal disease demonstrated by positron emission tomography. Annals of neurology. vol 38. issue 6. 1996-01-23. PMID:8526470. |
in the present report, [18f]fluorodopa positron emission tomography in 2 patients showed a marked dopaminergic denervation of the striatum, suggesting that this disease corresponds more to a nigropallidopyramidal dysfunction. |
1996-01-23 |
2023-08-12 |
Not clear |
P T Wong, H Feng, W L Te. Interaction of the dopaminergic and serotonergic systems in the rat striatum: effects of selective antagonists and uptake inhibitors. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501296. |
interaction of the dopaminergic and serotonergic systems in the rat striatum: effects of selective antagonists and uptake inhibitors. |
1996-01-18 |
2023-08-12 |
rat |
P T Wong, H Feng, W L Te. Interaction of the dopaminergic and serotonergic systems in the rat striatum: effects of selective antagonists and uptake inhibitors. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501296. |
they also support the idea that, in the rat striatum, presynaptic inhibitory heteroreceptors are a major mechanism that contributes to a reciprocal interaction of the dopaminergic and serotonergic systems. |
1996-01-18 |
2023-08-12 |
rat |
Y Akaneya, M Takahashi, H Hatanak. Survival of and 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity against dopaminergic neurons in coculture of rat mesencephalon with their target on non-target regions. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501301. |
it is known that dopaminergic neurons in the substantia nigra of the mesencephalon mainly project to the corpus striatum and neocortex, while the hippocampus receives major cholinergic projection from the septum. |
1996-01-18 |
2023-08-12 |
rat |
Y Akaneya, M Takahashi, H Hatanak. Survival of and 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity against dopaminergic neurons in coculture of rat mesencephalon with their target on non-target regions. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501301. |
in the present study, the ventral mesencephalon was cocultured with target regions of its dopaminergic neurons, the striatum and neocortex, and with non-target regions, the hippocampus, thalamus, colliculus and cerebellum, using embryonic day-17 (e17) rats. |
1996-01-18 |
2023-08-12 |
rat |
Y Akaneya, M Takahashi, H Hatanak. Survival of and 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity against dopaminergic neurons in coculture of rat mesencephalon with their target on non-target regions. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501301. |
the numbers of viable dopaminergic neurons were enhanced in coculture not only with corpus striatum or neocortex, but also with hippocampus or cerebellum. |
1996-01-18 |
2023-08-12 |
rat |
R L Dorri. Evidence for an action of araboascorbic acid on dopaminergic pathways of the corpus striatum. Pharmacology, biochemistry, and behavior. vol 52. issue 1. 1996-01-16. PMID:7501673. |
evidence for an action of araboascorbic acid on dopaminergic pathways of the corpus striatum. |
1996-01-16 |
2023-08-12 |
mouse |
R L Dorri. Evidence for an action of araboascorbic acid on dopaminergic pathways of the corpus striatum. Pharmacology, biochemistry, and behavior. vol 52. issue 1. 1996-01-16. PMID:7501673. |
the relative decrease in the 2 h accumulation of administered [3h]-spiperone (spi)-2 muci/kg, 0.0004 mg/kg, s.c. - in mouse corpus striatum, a brain area with a high dopaminergic input (specific plus nonspecific dopamine receptor ligand binding) and the cerebellum, a brain area with little, if any, dopaminergic input (an index of nonspecific dopamine receptor ligand binding) were used to compare the influence of araboascorbic acid (araa) with ascorbic acid (asa) on the dopamine receptor. |
1996-01-16 |
2023-08-12 |
mouse |
P M Laduro. Functional consequences of retrograde axonal transport of receptor-bound neurotensin. Trends in pharmacological sciences. vol 16. issue 10. 1996-01-04. PMID:7491711. |
the most compelling evidence that retrograde axonal transport of receptor-bound neuropeptide represents a long-distance signalling system in gene expression, discussed here by pierre laduron, comes from the recent observation that neurotensin injected in the striatum undergoes retrograde transport in dopaminergic neurones to the substantia nigra, where it induces in the cell bodies an increase of tyrosine hydroxylase mrna. |
1996-01-04 |
2023-08-12 |
Not clear |
J Tiihonen, J Kuikka, K Bergström, P Hakola, J Karhu, O P Ryynänen, J Föh. Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics. Nature medicine. vol 1. issue 7. 1995-12-28. PMID:7585146. |
animal studies suggest that development of substance dependence is associated with dopaminergic activity in striatum and the limbic system. |
1995-12-28 |
2023-08-12 |
human |
Z Elazar, N Peleg, M Paz, G Rin. The striatal dopaminergic catalepsy mechanism is not necessary for the expression of pontine catalepsy produced by carbachol injections into the pontine reticular formation. Naunyn-Schmiedeberg's archives of pharmacology. vol 352. issue 2. 1995-12-27. PMID:7477442. |
in the experiments described in the present article we studied the possibility that the pontine carbachol catalepsy is generated via the intermediary of the dopaminergic cataleptogenic mechanism in the striatum. |
1995-12-27 |
2023-08-12 |
rat |
A Gobert, J M Rivet, V Audinot, L Cistarelli, M Spedding, J Vian, J L Peglion, M J Milla. Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: II. Both D2 and "silent" D3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways. The Journal of pharmacology and experimental therapeutics. vol 275. issue 2. 1995-12-19. PMID:7473181. |
in conclusion, these data suggest that d3 (auto)receptors control synthesis and release of da in dopaminergic pathways innervating the limbic system, cortex and striatum. |
1995-12-19 |
2023-08-12 |
rat |
E H Stotz-Potter, B Ghetti, J R Simo. Endogenous serotonin release from the dopamine-deficient striatum of the weaver mutant mouse. Neurochemical research. vol 20. issue 7. 1995-12-15. PMID:7477675. |
in addition to an altered dopaminergic input, the striatum of the weaver mutant mouse (wv/wv) has increased serotonin tissue content and uptake compared to the wild-type mouse (+/+). |
1995-12-15 |
2023-08-12 |
mouse |
M F Suaud-Chagny, C Dugast, K Chergui, M Msghina, F Gono. Uptake of dopamine released by impulse flow in the rat mesolimbic and striatal systems in vivo. Journal of neurochemistry. vol 65. issue 6. 1995-12-15. PMID:7595557. |
the release of dopamine in the striatum, nucleus accumbens, and olfactory tubercle of anesthetized rats was evoked by electrical stimulation of the mesolimbic dopaminergic pathway (four pulses at 15 hz or four pulses at 200 hz). |
1995-12-15 |
2023-08-12 |
rat |
M F Suaud-Chagny, C Dugast, K Chergui, M Msghina, F Gono. Uptake of dopamine released by impulse flow in the rat mesolimbic and striatal systems in vivo. Journal of neurochemistry. vol 65. issue 6. 1995-12-15. PMID:7595557. |
these results show in vivo that these uptake inhibitors actually slow the clearance of dopamine released by action potentials and suggest that dopaminergic transmission is both prolonged and potentiated strongly by these drugs, in particular in the striatum. |
1995-12-15 |
2023-08-12 |
rat |
M F Chesselet, J J Soghomonian, P Sali. Anatomical localization and regulation of somatostatin gene expression in the basal ganglia and its clinical implications. Ciba Foundation symposium. vol 190. 1995-12-06. PMID:7587652. |
further evidence for a role for striatal somatostatin in extrapyramidal symptoms includes the observation that somatostatin mrna levels decrease in the striatum after lesions are made in the dopaminergic pathway, a feature of parkinson's disease. |
1995-12-06 |
2023-08-12 |
human |
R Levy, M T Herrero, M Ruberg, J Villares, B Faucheux, J Guridi, J Guillen, M R Luquin, F Javoy-Agid, J A Obes. Effects of nigrostriatal denervation and L-dopa therapy on the GABAergic neurons in the striatum in MPTP-treated monkeys and Parkinson's disease: an in situ hybridization study of GAD67 mRNA. The European journal of neuroscience. vol 7. issue 6. 1995-12-05. PMID:7582093. |
these data suggest that in mptp-treated monkeys the degeneration of nigrostriatal dopaminergic neurons results in a generalized increase in gabaergic activity in all the gabaergic neurons of the striatum, which is partially reversed by l-dopa therapy. |
1995-12-05 |
2023-08-12 |
monkey |
J M Delfs, V M Ciaramitaro, T J Parry, M F Chessele. Subthalamic nucleus lesions: widespread effects on changes in gene expression induced by nigrostriatal dopamine depletion in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 10. 1995-12-04. PMID:7472418. |
confirming previous results, nigrostriatal dopaminergic lesions caused contraversive rotation after apomorphine injection, and increased enkephalin mrna in the striatum, gad mrna in the globus pallidus, and somatostatin mrna in the entopeduncular nucleus (internal pallidum) ipsilateral to the lesion. |
1995-12-04 |
2023-08-12 |
rat |