| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Gygi, J W Gibb, G R Hanso. Methcathinone: an initial study of its effects on monoaminergic systems. The Journal of pharmacology and experimental therapeutics. vol 276. issue 3. 1996-09-20. PMID:8786536. |
multiple doses of 30 mg/kg methcathinone caused dramatic decreases in neurochemical parameters associated with both dopaminergic and serotonergic systems in the striatum; corresponding decreases also occurred in serotonergic parameters in hippocampus and frontal cortex. |
1996-09-20 |
2023-08-12 |
rat |
| E Gil-Martín, I Colado, A Fernández-López, A Fernández-Briera, P Calv. Effects of an acute dose of ethanol on dopaminergic and serotonergic systems from rat cerebral cortex and striatum. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. vol 113. issue 3. 1996-09-05. PMID:8697197. |
effects of an acute dose of ethanol on dopaminergic and serotonergic systems from rat cerebral cortex and striatum. |
1996-09-05 |
2023-08-12 |
rat |
| T G Hastings, D A Lewis, M J Zigmon. Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 5. 1996-09-05. PMID:8700866. |
thus, following its oxidation, dopamine in high concentrations binds to protein in the striatum, an event that is correlated with the specific loss of dopaminergic terminals. |
1996-09-05 |
2023-08-12 |
rat |
| J D Elsworth, M S Brittan, J R Taylor, J R Sladek, M S al-Tikriti, Y Zea-Ponce, R B Innis, D E Redmond, R H Rot. Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys. Cell transplantation. vol 5. issue 2. 1996-08-27. PMID:8689042. |
it is possible that the number of fetal dopamine neurons that survive transplantation is insufficient to restore dopaminergic innervation of the large human striatum to a level where striking recovery is obtained. |
1996-08-27 |
2023-08-12 |
human |
| W R Galpern, L H Burns, T W Deacon, J Dinsmore, O Isacso. Xenotransplantation of porcine fetal ventral mesencephalon in a rat model of Parkinson's disease: functional recovery and graft morphology. Experimental neurology. vol 140. issue 1. 1996-08-19. PMID:8682173. |
using the 6-hydroxydopamine rat model of pd, we transplanted dopaminergic neurons derived from embryonic day 27 porcine fetuses into the denervated striatum of cyclosporine-a (cya)-treated or non-cya-treated rats. |
1996-08-19 |
2023-08-12 |
human |
| R Schade, K Vick, T Ott, R Sohr, C Pfister, J Bellach, G Golor, B Lemme. Circadian rhythms of dopamine and cholecystokinin in nucleus accumbens and striatum of rats--influence on dopaminergic stimulation. Chronobiology international. vol 12. issue 2. 1996-07-31. PMID:8653803. |
circadian rhythms of dopamine and cholecystokinin in nucleus accumbens and striatum of rats--influence on dopaminergic stimulation. |
1996-07-31 |
2023-08-12 |
rat |
| H Asada, P A Kaseloo, A Lis, D M Petti, R J Plunket. Traumatized rat striatum produces neurite-promoting and neurotrophic activities in vitro. Experimental neurology. vol 139. issue 2. 1996-07-31. PMID:8654521. |
cntf, or other neurotrophic factors present in the traumatized striatum, may be involved in the dopaminergic fiber sprouting seen following cavitation or graft implantation in animal models of parkinson's disease. |
1996-07-31 |
2023-08-12 |
human |
| B Y Zeng, P Jenner, C D Marsde. Altered motor function and graft survival produced by basic fibroblast growth factor in rats with 6-OHDA lesions and fetal ventral mesencephalic grafts are associated with glial proliferation. Experimental neurology. vol 139. issue 2. 1996-07-31. PMID:8654524. |
we have investigated the effect of treating fetal ventral mesencephalon with bfgf or nerve growth factor (ngf) on the subsequent survival and function of grafted dopaminergic neurons implanted into the striatum of rats with a unilateral 6-hydroxydopamine lesion. |
1996-07-31 |
2023-08-12 |
rat |
| S B Wirth, M Rufer, K Unsicke. Early effects of FGF-2 on glial cells in the MPTP-lesioned striatum. Experimental neurology. vol 137. issue 2. 1996-07-11. PMID:8635534. |
fibroblast growth factor-2 (fgf-2), locally administered in gelfoam to the striatum of mice treated with the neurotoxic drug 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), has restorative and neuroprotective effects on dopaminergic neurons and associated striatal transmitter systems. |
1996-07-11 |
2023-08-12 |
mouse |
| S Delion, S Chalon, D Guilloteau, J C Besnard, G Duran. alpha-Linolenic acid dietary deficiency alters age-related changes of dopaminergic and serotoninergic neurotransmission in the rat frontal cortex. Journal of neurochemistry. vol 66. issue 4. 1996-06-25. PMID:8627314. |
the effects of alpha-linolenic acid diet deficiency on rat dopaminergic and serotoninergic neurotransmission systems were investigated in the frontal cortex, striatum, and cerebellum of male rats 2,6,12, and 24 months of age. |
1996-06-25 |
2023-08-12 |
rat |
| S Delion, S Chalon, D Guilloteau, J C Besnard, G Duran. alpha-Linolenic acid dietary deficiency alters age-related changes of dopaminergic and serotoninergic neurotransmission in the rat frontal cortex. Journal of neurochemistry. vol 66. issue 4. 1996-06-25. PMID:8627314. |
in the striatum and cerebellum, dopaminergic and serotoninergic receptor densities and endogenous dopamine and serotonin levels were affected by aging regardless of the diet. |
1996-06-25 |
2023-08-12 |
rat |
| H Takechi, K Matsumura, Y Watanabe, K Kato, R Noyori, M Suzuki, Y Watanab. A novel subtype of the prostacyclin receptor expressed in the central nervous system. The Journal of biological chemistry. vol 271. issue 10. 1996-06-20. PMID:8621463. |
hemilesion studies of striatal neurons lesioned by kainate or of dopaminergic afferents lesioned by 6-hydroxydopamine revealed that the binding sites of the novel subtype exist on neuronal cells in the striatum, but not on the presynaptic terminal of afferents or on glial cells. |
1996-06-20 |
2023-08-12 |
rat |
| L Antkiewicz-Michaluk, I Romańska, J Vetulan. Immediate and "day-after" effects of morphine on dopamine and serotonin metabolism in various structures of the rat brain. Polish journal of pharmacology. vol 47. issue 4. 1996-06-12. PMID:8616517. |
the effects of a single dose of 20 mg/kg ip of morphine on dopaminergic and serotonergic systems in the limbic (cortex, nucleus accumbens) and extrapyramidal (striatum) structures were investigated in rats. |
1996-06-12 |
2023-08-12 |
rat |
| b' A Parent, M C Asselin, P Y C\\xc3\\xb4t\\xc3\\xa. Dopaminergic regulation of peptide gene expression in the striatum of normal and parkinsonian monkeys. Advances in neurology. vol 69. 1996-05-31. PMID:8615187.' |
dopaminergic regulation of peptide gene expression in the striatum of normal and parkinsonian monkeys. |
1996-05-31 |
2023-08-12 |
monkey |
| T Kano, Y Suzuki, M Shibuya, K Kiuchi, M Hagiwar. Cocaine-induced CREB phosphorylation and c-Fos expression are suppressed in Parkinsonism model mice. Neuroreport. vol 6. issue 16. 1996-04-18. PMID:8595201. |
these data suggest that creb may play a major role in the dopaminergic activation of c-fos in the striatum and that the lack of a creb-induced transcription cascade may have a critical relevance for long-lasting psychomotor disorders in parkinsonism. |
1996-04-18 |
2023-08-12 |
mouse |
| V Steffen, M Santiago, C P de la Cruz, E Revilla, A Machado, J Can. Effect of intraventricular injection of 1-methyl-4-phenylpyridinium: protection by acetyl-L-carnitine. Human & experimental toxicology. vol 14. issue 11. 1996-03-28. PMID:8588946. |
the neurotoxic action of mpp+ injected intracerebroventricularly (icv) in the rat has been studied, using dopaminergic systems in the substantia nigra, striatum, olfactory bulb, median eminence and hypophysis. |
1996-03-28 |
2023-08-12 |
rat |
| Y Yoshimoto, Q Lin, T J Collier, D M Frim, X O Breakefield, M C Boh. Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson's disease. Brain research. vol 691. issue 1-2. 1996-03-25. PMID:8590062. |
to determine whether increased levels of biologically produced bdnf affect the function or regeneration of damaged dopaminergic neurons, the effects of grafting astrocytes transduced with the human bdnf gene into the striatum of the partially lesioned hemiparkinsonian rat were examined. |
1996-03-25 |
2023-08-12 |
human |
| C Gagnon, B Gomez-Mancilla, R Markstein, P J Bédard, T Di Paol. Effect of adding the D-1 agonist CY 208-243 to chronic bromocriptine treatment of MPTP-monkeys: regional changes of brain dopamine receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 4. 1996-03-22. PMID:8588064. |
in the posterior striatum, both dopaminergic treatments decreased towards control values [3h]-sch 23390, [3h]-spiperone and [3h]-n-n-propylnorapomorphine binding whereas they did not significantly change [3h]-skf 38393 specific binding. |
1996-03-22 |
2023-08-12 |
monkey |
| E Nwanze, F Souverbie, G Jonsson, E Sundströ. Regional biotransformation of MPTP in the CNS of rodents and its relation to neurotoxicity. Neurotoxicology. vol 16. issue 3. 1996-03-18. PMID:8584278. |
neither previous lesions of catecholamine terminals in striatum or the frontal cortex, nor pretreatment with a dopamine uptake blocker affected the synthesis of mpp+, showing that the conversion of mptp to mpp+ is taking place outside both dopaminergic and noradrenergic neurons. |
1996-03-18 |
2023-08-12 |
mouse |
| L Cao, Z C Zheng, Y C Zhao, Z H Jiang, Z G Liu, S D Chen, C F Zhou, X Y Li. Gene therapy of Parkinson disease model rat by direct injection of plasmid DNA-lipofectin complex. Human gene therapy. vol 6. issue 11. 1996-03-14. PMID:8573622. |
the rotational asymmetry of parkinson disease model rat was reduced quickly and significantly, suggesting that plasmid-dna-transfected brain cells can generate l-dopa locally in the striatum in quantities sufficient to compensate partially for the loss of intrinsic striatal dopaminergic input. |
1996-03-14 |
2023-08-12 |
rat |