| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tobias U Hauser, Eran Eldar, Raymond J Dola. Separate mesocortical and mesolimbic pathways encode effort and reward learning signals. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 35. 2018-06-11. PMID:28808037. |
we show a common mesencephalic origin for these signals evident in overlapping, but spatially dissociable, dopaminergic midbrain regions expressing both types of pe. |
2018-06-11 |
2023-08-13 |
Not clear |
| Yan Gu, Xueping Hu, Weigang Pan, Chun Yang, Lijun Wang, Yiyuan Li, Antao Che. Neural Activities Underlying the Feedback Express Salience Prediction Errors for Appetitive and Aversive Stimuli. Scientific reports. vol 6. 2018-06-06. PMID:27694920. |
the feedback-related negativity (frn), a frontocentral negative deflection after the delivery of feedback, has been found to be larger for outcomes that are worse than expected, and it reflects a reward prediction error derived from the midbrain dopaminergic projections to the anterior cingulate cortex (acc), as stated in reinforcement learning theory. |
2018-06-06 |
2023-08-13 |
Not clear |
| Melanie Feuerstein, Enaam Chleilat, Shokoufeh Khakipoor, Konstantinos Michailidis, Christian Ophoven, Eleni Rouss. Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line. Cell and tissue research. vol 370. issue 2. 2018-06-05. PMID:28799057. |
the temporal dynamic expression of sonic hedgehog (shh) and signaling during early midbrain dopaminergic (mda) neuron development is one of the key players in establishing mda progenitor diversity. |
2018-06-05 |
2023-08-13 |
mouse |
| Melanie Feuerstein, Enaam Chleilat, Shokoufeh Khakipoor, Konstantinos Michailidis, Christian Ophoven, Eleni Rouss. Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line. Cell and tissue research. vol 370. issue 2. 2018-06-05. PMID:28799057. |
moreover, we examine the expression and regulation of dopaminergic neuronal progenitor markers, midbrain dopaminergic neuronal markers and markers of the shh signaling pathway in undifferentiated and butyric acid-treated (differentiated) mn9d cells in the presence or absence of exogenous shh in vitro by rt-pcr, immunoblotting and immunocytochemistry. |
2018-06-05 |
2023-08-13 |
mouse |
| Hiroshi Ito, Hiroshi Kawaguchi, Fumitoshi Kodaka, Hiroyuki Takuwa, Yoko Ikoma, Hitoshi Shimada, Yasuyuki Kimura, Chie Seki, Hitoshi Kubo, Shiro Ishii, Harumasa Takano, Tetsuya Suhar. Normative data of dopaminergic neurotransmission functions in substantia nigra measured with MRI and PET: Neuromelanin, dopamine synthesis, dopamine transporters, and dopamine D NeuroImage. vol 158. 2018-06-01. PMID:28655632. |
in the present study, the normative data of dopaminergic neurotransmission functions in the midbrain, consisting of neuromelanin, dopamine synthesis, dopamine transporters and dopamine d |
2018-06-01 |
2023-08-13 |
Not clear |
| Michael S Cohen, Jesse Rissman, Mariam Hovhannisyan, Alan D Castel, Barbara J Knowlto. Free recall test experience potentiates strategy-driven effects of value on memory. Journal of experimental psychology. Learning, memory, and cognition. vol 43. issue 10. 2018-05-29. PMID:28394160. |
by another mechanism, information paired with value or reward is automatically strengthened in memory via dopaminergic projections from midbrain to hippocampus (shohamy & adcock, 2010). |
2018-05-29 |
2023-08-13 |
human |
| Rui-Fang Dong, Bing Zhang, Li-Wen Tai, Hong-Mei Liu, Fang-Kun Shi, Ning-Ning Li. The Neuroprotective Role of MiR-124-3p in a 6-Hydroxydopamine-Induced Cell Model of Parkinson's Disease via the Regulation of ANAX5. Journal of cellular biochemistry. vol 119. issue 1. 2018-05-29. PMID:28543594. |
parkinson's disease (pd), the second most common neurodegenerative disorder, is characterized by a progressive loss of dopaminergic neurons in the midbrain. |
2018-05-29 |
2023-08-13 |
Not clear |
| S N Suresh, Aravinda K Chavalmane, Vidyadhara Dj, Haorei Yarreiphang, Shashank Rai, Abhik Paul, James P Clement, Phalguni Anand Alladi, Ravi Manjithay. A novel autophagy modulator 6-Bio ameliorates SNCA/α-synuclein toxicity. Autophagy. vol 13. issue 7. 2018-05-25. PMID:28350199. |
importantly, neuroprotective function of 6-bio as envisaged by immunohistology and behavior analyses in a preclinical model of pd where it induces autophagy in dopaminergic (daergic) neurons of mice midbrain to clear toxic protein aggregates suggesting that it could be a potential therapeutic candidate for protein conformational disorders. |
2018-05-25 |
2023-08-13 |
mouse |
| Sonja C Schriever, Annemarie Zimprich, Katrin Pfuhlmann, Peter Baumann, Florian Giesert, Valentina Klaus, Dhiraj G Kabra, Ulrich Hafen, Artem Romanov, Matthias H Tschöp, Wolfgang Wurst, Marcus Conrad, Sabine M Hölter, Daniela Vogt Weisenhorn, Paul T Pfluge. Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency. Neuroscience. vol 357. 2018-05-22. PMID:28627418. |
gpx4 was deleted from either agrp or pomc neurons in the hypothalamus, essential for metabolic homeostasis, or from dopaminergic neurons in the ventral midbrain, governing behaviors such as anxiety or voluntary movement. |
2018-05-22 |
2023-08-13 |
mouse |
| Sonja C Schriever, Annemarie Zimprich, Katrin Pfuhlmann, Peter Baumann, Florian Giesert, Valentina Klaus, Dhiraj G Kabra, Ulrich Hafen, Artem Romanov, Matthias H Tschöp, Wolfgang Wurst, Marcus Conrad, Sabine M Hölter, Daniela Vogt Weisenhorn, Paul T Pfluge. Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency. Neuroscience. vol 357. 2018-05-22. PMID:28627418. |
to exacerbate oxidative stress in dopaminergic neurons of the ventral midbrain, we systemically co-deleted the pd-related gene dj-1. |
2018-05-22 |
2023-08-13 |
mouse |
| Sonja C Schriever, Annemarie Zimprich, Katrin Pfuhlmann, Peter Baumann, Florian Giesert, Valentina Klaus, Dhiraj G Kabra, Ulrich Hafen, Artem Romanov, Matthias H Tschöp, Wolfgang Wurst, Marcus Conrad, Sabine M Hölter, Daniela Vogt Weisenhorn, Paul T Pfluge. Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency. Neuroscience. vol 357. 2018-05-22. PMID:28627418. |
moreover, gpx4 appears to constitute an important rheostat against neuronal dysfunction and pd-like symptoms in dopaminergic circuitry within the ventral midbrain. |
2018-05-22 |
2023-08-13 |
mouse |
| Denis Pavă. A Dopamine Hypothesis of Autism Spectrum Disorder. Developmental neuroscience. vol 39. issue 5. 2018-05-22. PMID:28750400. |
in this paper, we present such a hypothesis by proposing that autistic behavior arises from dysfunctions in the midbrain dopaminergic system. |
2018-05-22 |
2023-08-13 |
human |
| Nicole Gennet, Claudia Tamburini, Xinsheng Nan, Meng L. FolR1: a novel cell surface marker for isolating midbrain dopamine neural progenitors and nascent dopamine neurons. Scientific reports. vol 6. 2018-05-16. PMID:27580818. |
midbrain dopaminergic neurons (mesda) are the nerve cells preferentially lost in the brains of parkinson's disease patients. |
2018-05-16 |
2023-08-13 |
mouse |
| Mi Wang, Wael Saasouh, Thomas Botsford, Allen Keebler, Andrew Zura, Michael S Benninger, Rafi Avitsia. Postoperative Stridor and Acute Respiratory Failure After Parkinson Disease Deep Brain Stimulator Placement: Case Report and Review of Literature. World neurosurgery. vol 111. 2018-05-15. PMID:29229347. |
parkinson disease (pd), a neurodegenerative disorder characterized by loss of dopaminergic neurons in the substantia nigra of the midbrain, is commonly thought of as a motion disorder, but it can have significant effect on the respiratory system. |
2018-05-15 |
2023-08-13 |
Not clear |
| Arjun Ramakrishnan, Yoon Woo Byun, Kyle Rand, Christian E Pedersen, Mikhail A Lebedev, Miguel A L Nicoleli. Cortical neurons multiplex reward-related signals along with sensory and motor information. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 24. 2018-05-14. PMID:28559307. |
this influence can be exerted directly upon the primary motor (m1) and somatosensory (s1) cortical areas via the projections from reward-sensitive dopaminergic neurons of the midbrain ventral tegmental areas. |
2018-05-14 |
2023-08-13 |
monkey |
| Rachel A Cliburn, Amy R Dunn, Kristen A Stout, Carlie A Hoffman, Kelly M Lohr, Alison I Bernstein, Emily J Winokur, James Burkett, Yvonne Schmitz, William M Caudle, Gary W Mille. Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain. Journal of chemical neuroanatomy. vol 83-84. 2018-05-11. PMID:27836486. |
we show the distribution of vmat2 in monoaminergic brain regions of mouse brain, notably the midbrain, striatum, olfactory tubercle, dopaminergic paraventricular nuclei, tuberomammillary nucleus, raphe nucleus, and locus coeruleus. |
2018-05-11 |
2023-08-13 |
mouse |
| Panojot Bifsha, Aurelio Balsalobre, Jacques Droui. Specificity of Pitx3-Dependent Gene Regulatory Networks in Subsets of Midbrain Dopamine Neurons. Molecular neurobiology. vol 54. issue 7. 2018-05-10. PMID:27514757. |
dysfunction of midbrain dopaminergic (mda) neurons is involved in parkinson's disease (pd) and neuropsychiatric disorders. |
2018-05-10 |
2023-08-13 |
human |
| Zuzanna Kurowska, Michael Jewett, Per Ludvik Brattås, Itzia Jimenez-Ferrer, Xuyian Kenéz, Tomas Björklund, Ulrika Nordström, Patrik Brundin, Maria Swanber. Identification of Multiple QTLs Linked to Neuropathology in the Engrailed-1 Heterozygous Mouse Model of Parkinson's Disease. Scientific reports. vol 6. 2018-05-09. PMID:27550741. |
motor symptoms in parkinson's disease are attributed to degeneration of midbrain dopaminergic neurons (dns). |
2018-05-09 |
2023-08-13 |
mouse |
| Dan P Covey, Yolanda Mateo, David Sulzer, Joseph F Cheer, David M Lovinge. Endocannabinoid modulation of dopamine neurotransmission. Neuropharmacology. vol 124. 2018-05-09. PMID:28450060. |
the dopaminergic midbrain innervates numerous brain regions where extracellular da release and receptor binding promote short- and long-term changes in postsynaptic neuron function. |
2018-05-09 |
2023-08-13 |
Not clear |
| Ammar Natalwala, Tilo Kunat. Preparation, characterization, and banking of clinical-grade cells for neural transplantation: Scale up, fingerprinting, and genomic stability of stem cell lines. Progress in brain research. vol 230. 2018-05-01. PMID:28552226. |
parkinson's disease is a complex and progressive neurodegenerative condition that is characterized by the severe loss of midbrain dopaminergic (mda) neurons, which innervate the striatum. |
2018-05-01 |
2023-08-13 |
human |