Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Y Iwahori, H Saito, K Torii, N Nishiyam. Activin exerts a neurotrophic effect on cultured hippocampal neurons. Brain research. vol 760. issue 1-2. 1997-10-28. PMID:9237517. |
it is also a potent survival factor for neurogenic clonal cell lines, retinal neurons and midbrain dopaminergic neurons. |
1997-10-28 |
2023-08-12 |
rat |
P P Michel, M Ruberg, Y Agi. Rescue of mesencephalic dopamine neurons by anticancer drug cytosine arabinoside. Journal of neurochemistry. vol 69. issue 4. 1997-10-27. PMID:9326279. |
our results suggest a possible mechanism underlying neurodegeneration in parkinson's disease, where selective loss of dopaminergic neurons in the mesencephalon is accompanied by astrogliosis. |
1997-10-27 |
2023-08-12 |
Not clear |
R H Farkas, P Y Chien, S Nakajima, Y Nakajim. Neurotensin and dopamine D2 activation oppositely regulate the same K+ conductance in rat midbrain dopaminergic neurons. Neuroscience letters. vol 231. issue 1. 1997-10-23. PMID:9280158. |
neurotensin and dopamine d2 activation oppositely regulate the same k+ conductance in rat midbrain dopaminergic neurons. |
1997-10-23 |
2023-08-12 |
rat |
R H Farkas, P Y Chien, S Nakajima, Y Nakajim. Neurotensin and dopamine D2 activation oppositely regulate the same K+ conductance in rat midbrain dopaminergic neurons. Neuroscience letters. vol 231. issue 1. 1997-10-23. PMID:9280158. |
midbrain dopaminergic neurons are excited by neurotensin (nt) and inhibited by dopamine. |
1997-10-23 |
2023-08-12 |
rat |
F M Göldner, K T Dineley, J W Patric. Immunohistochemical localization of the nicotinic acetylcholine receptor subunit alpha6 to dopaminergic neurons in the substantia nigra and ventral tegmental area. Neuroreport. vol 8. issue 12. 1997-10-23. PMID:9295110. |
alpha6 immunoreactivity was found to be present in the substantia nigra, the ventral tegmental area, the locus coeruleus and the medial habenula, and double-labeling for tyrosine hydroxylase demonstrated that the alpha6 protein is present on dopaminergic neurons of the midbrain. |
1997-10-23 |
2023-08-12 |
rat |
J Jordan, M Böttner, H J Schluesener, K Unsicker, K Krieglstei. Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells. The European journal of neuroscience. vol 9. issue 8. 1997-10-16. PMID:9283824. |
bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells. |
1997-10-16 |
2023-08-12 |
rat |
J Jordan, M Böttner, H J Schluesener, K Unsicker, K Krieglstei. Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells. The European journal of neuroscience. vol 9. issue 8. 1997-10-16. PMID:9283824. |
we studied potential neurotrophic effects of bmps on the in vitro survival, transmitter uptake and protection against mpp+ toxicity of mesencephalic dopaminergic neurons cultured from the embryonic midbrain floor at embryonic day (e) 14. |
1997-10-16 |
2023-08-12 |
rat |
J Jordan, M Böttner, H J Schluesener, K Unsicker, K Krieglstei. Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells. The European journal of neuroscience. vol 9. issue 8. 1997-10-16. PMID:9283824. |
we conclude that several bmps share a neurotrophic capacity for dopaminergic midbrain neurons with other members of the tgf-beta superfamily, but act indirectly, possibly through glial cells. |
1997-10-16 |
2023-08-12 |
rat |
D S Albeck, B J Hoffer, D Quissell, L A Sanders, G Zerbe, A C Granhol. A non-invasive transport system for GDNF across the blood-brain barrier. Neuroreport. vol 8. issue 9-10. 1997-10-07. PMID:9243628. |
glial cell line-derived neurotrophic factor (gdnf) is a neurotrophin which supports midbrain dopaminergic neurons and spinal cord motorneurons. |
1997-10-07 |
2023-08-12 |
Not clear |
D S Albeck, B J Hoffer, D Quissell, L A Sanders, G Zerbe, A C Granhol. A non-invasive transport system for GDNF across the blood-brain barrier. Neuroreport. vol 8. issue 9-10. 1997-10-07. PMID:9243628. |
this suggests that the ox-26-gdnf conjugate could be utilized for non-invasive treatment of neurodegenerative diseases of the spinal cord or midbrain dopaminergic neurons. |
1997-10-07 |
2023-08-12 |
Not clear |
N Miao, M Wang, J A Ott, J S D'Alessandro, T M Woolf, D A Bumcrot, N K Mahanthappa, K Pan. Sonic hedgehog promotes the survival of specific CNS neuron populations and protects these cells from toxic insult In vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 15. 1997-10-03. PMID:9221786. |
for example, shh induces the differentiation of motor neurons in the spinal cord and dopaminergic neurons in the midbrain. |
1997-10-03 |
2023-08-12 |
rat |
N Miao, M Wang, J A Ott, J S D'Alessandro, T M Woolf, D A Bumcrot, N K Mahanthappa, K Pan. Sonic hedgehog promotes the survival of specific CNS neuron populations and protects these cells from toxic insult In vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 15. 1997-10-03. PMID:9221786. |
5) rat ventral mesencephalon, we show that shh is also trophic for dopaminergic neurons. |
1997-10-03 |
2023-08-12 |
rat |
M Hynes, D M Stone, M Dowd, S Pitts-Meek, A Goddard, A Gurney, A Rosentha. Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1. Neuron. vol 19. issue 1. 1997-10-02. PMID:9247260. |
further, ectopic expression of gli-1 in the dorsal midbrain and hindbrain of transgenic mice mimics the effects of ectopically expressed shh-n, leading to the activation of ventral neural tube markers such as ptc, hnf-3beta, and shh; to the suppression of dorsal markers such as pax-3 and al-1; and to the formation of ectopic dorsal clusters of dopaminergic and serotonergic neurons. |
1997-10-02 |
2023-08-12 |
mouse |
L Won, B Ghetti, B Heller, A Helle. In vitro evidence that the reduction in mesencephalic dopaminergic neurons in the weaver heterozygote is not due to a failure in target cell interaction. Experimental brain research. vol 115. issue 1. 1997-09-12. PMID:9224846. |
at both culture time points, aggregates containing wv/+ mesencephalon coaggregated with either wv/+ or +/+ striatum contained fewer dopaminergic neurons than mesencephalic-striatal cultures composed of only +/+ cells. |
1997-09-12 |
2023-08-12 |
mouse |
L Won, B Ghetti, B Heller, A Helle. In vitro evidence that the reduction in mesencephalic dopaminergic neurons in the weaver heterozygote is not due to a failure in target cell interaction. Experimental brain research. vol 115. issue 1. 1997-09-12. PMID:9224846. |
coaggregation of +/+ mesencephalon with wv/+ striatum did not have a detrimental effect on dopaminergic cell number. |
1997-09-12 |
2023-08-12 |
mouse |
L Won, B Ghetti, B Heller, A Helle. In vitro evidence that the reduction in mesencephalic dopaminergic neurons in the weaver heterozygote is not due to a failure in target cell interaction. Experimental brain research. vol 115. issue 1. 1997-09-12. PMID:9224846. |
since the coculture of +/+ striatum with wv/+ mesencephalon did not appear to rescue wv/+ dopaminergic neurons in the aggregates as compared to wv/+ striatum and, wv/+ striatum proved to be a perfectly adequate target for +/+ mesencephalic dopaminergic neurons, it appears that the effect of the wv gene is on the dopaminergic neurons themselves. |
1997-09-12 |
2023-08-12 |
mouse |
b' V Santucci, C Gueudet, R Steinberg, G Le Fur, P Soubri\\xc3\\xa. Involvement of cortical neurotensin in the regulation of rat meso-cortico-limbic dopamine neurons: evidence from changes in the number of spontaneously active A10 cells after neurotensin receptor blockade. Synapse (New York, N.Y.). vol 26. issue 4. 1997-09-09. PMID:9215596.' |
in order to further assess the role of endogenous neurotensin on midbrain dopaminergic neuronal function, the effects of the selective neurotensin receptor antagonists sr 48692 and sr 48527 were investigated on the number of spontaneously active a9 and a10 dopaminergic neurons in rats. |
1997-09-09 |
2023-08-12 |
rat |
S K Mukherjee, L K Klaidman, R Yasharel, J D Adam. Increased brain NAD prevents neuronal apoptosis in vivo. European journal of pharmacology. vol 330. issue 1. 1997-09-02. PMID:9228411. |
mptp selectively damages dopaminergic neurons in the substantia nigra of the midbrain. |
1997-09-02 |
2023-08-12 |
Not clear |
F X Castellano. Toward a pathophysiology of attention-deficit/hyperactivity disorder. Clinical pediatrics. vol 36. issue 7. 1997-08-21. PMID:9241475. |
anatomic neuroimaging studies suggest that the relevant regulatory circuits include the prefrontal cortex and the basal ganglia, which are modulated by dopaminergic innervation from the midbrain and by stimulant medications. |
1997-08-21 |
2023-08-12 |
Not clear |
J Wei, S R Dlouhy, S Bayer, R Piva, T Verina, Y Wang, Y Feng, B Dupree, M E Hodes, B Ghett. In situ hybridization analysis of Girk2 expression in the developing central nervous system in normal and weaver mice. Journal of neuropathology and experimental neurology. vol 56. issue 7. 1997-08-07. PMID:9210872. |
of the pathologic abnormalities, the best studied is the neuronal degeneration that occurs in the cerebellar cortex and in the midbrain dopaminergic neurons. |
1997-08-07 |
2023-08-12 |
mouse |