| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Satoshi Kutsuna, Ryosuke Tsuruta, Motoki Fujita, Masaki Todani, Takeshi Yagi, Yasuaki Ogino, Masatsugu Igarashi, Koshiro Takahashi, Tomonori Izumi, Shunji Kasaoka, Makoto Yuasa, Tsuyoshi Maekaw. Cholinergic agonist physostigmine suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in rats with forebrain ischemia/reperfusion. Brain research. vol 1313. 2010-04-05. PMID:19968973. |
cholinergic agonist physostigmine suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in rats with forebrain ischemia/reperfusion. |
2010-04-05 |
2023-08-12 |
rat |
| Satoshi Kutsuna, Ryosuke Tsuruta, Motoki Fujita, Masaki Todani, Takeshi Yagi, Yasuaki Ogino, Masatsugu Igarashi, Koshiro Takahashi, Tomonori Izumi, Shunji Kasaoka, Makoto Yuasa, Tsuyoshi Maekaw. Cholinergic agonist physostigmine suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in rats with forebrain ischemia/reperfusion. Brain research. vol 1313. 2010-04-05. PMID:19968973. |
in this study, we investigated the effects of the cholinergic agonist, physostigmine, on jugular venous superoxide radical (o(2)(-)) generation, oxidative stress, early inflammation, and endothelial activation during forebrain ischemia/reperfusion (fbi/r) in rats. |
2010-04-05 |
2023-08-12 |
rat |
| Lorenza Magno, Vincenzo Catanzariti, Robert Nitsch, Heiko Krude, Thomas Nauman. Ongoing expression of Nkx2.1 in the postnatal mouse forebrain: potential for understanding NKX2.1 haploinsufficiency in humans? Brain research. vol 1304. 2010-01-28. PMID:19766601. |
double immunocytochemistry for nkx2.1 and various neuronal markers revealed that mainly parvalbumin-containing gabaergic neurons, but also cholinergic neurons, of the ventral forebrain express this protein. |
2010-01-28 |
2023-08-12 |
mouse |
| John Smythie. Philosophy, perception, and neuroscience. Perception. vol 38. issue 5. 2010-01-27. PMID:19662940. |
this involves particularly the cholinergic system in the forebrain. |
2010-01-27 |
2023-08-12 |
Not clear |
| Nobuaki Matsui, Kazuki Takahashi, Miho Takeichi, Touma Kuroshita, Kaori Noguchi, Kana Yamazaki, Hideaki Tagashira, Kenichi Tsutsui, Hideki Okada, Yuki Kido, Yumiko Yasui, Nobuyuki Fukuishi, Yoshiyasu Fukuyama, Masaaki Akag. Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice. Brain research. vol 1305. 2010-01-05. PMID:19815000. |
these results suggest that magnolol and honokiol prevent age-related learning and memory impairment by preserving cholinergic neurons in the forebrain. |
2010-01-05 |
2023-08-12 |
mouse |
| Farshad Homayouni Moghadam, Hojatoallah Alaie, Khadije Karbalaie, Somayeh Tanhaei, Mohammad Hossein Nasr Esfahani, Hossein Baharvan. Transplantation of primed or unprimed mouse embryonic stem cell-derived neural precursor cells improves cognitive function in Alzheimerian rats. Differentiation; research in biological diversity. vol 78. issue 2-3. 2009-12-03. PMID:19616885. |
neuropathological features include the progressive degeneration of cholinergic neurons in the forebrain cholinergic projection system especially nucleus basalis of meynert (nbm). |
2009-12-03 |
2023-08-12 |
mouse |
| Lei Ma, Matthew A Seager, Matthew Seager, Marion Wittmann, Marlene Jacobson, Denise Bickel, Maryann Burno, Keith Jones, Valerie Kuzmick Graufelds, Guangping Xu, Michelle Pearson, Alexander McCampbell, Renee Gaspar, Paul Shughrue, Andrew Danziger, Christopher Regan, Rose Flick, Danette Pascarella, Susan Garson, Scott Doran, Constantine Kreatsoulas, Lone Veng, Craig W Lindsley, William Shipe, Scott Kuduk, Cyrille Sur, Gene Kinney, Guy R Seabrook, William J Ra. Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 37. 2009-11-13. PMID:19717450. |
the forebrain cholinergic system promotes higher brain function in part by signaling through the m(1) muscarinic acetylcholine receptor (machr). |
2009-11-13 |
2023-08-12 |
mouse |
| Kunio Kitamura, Yukiko Itou, Masako Yanazawa, Maki Ohsawa, Rika Suzuki-Migishima, Yuko Umeki, Hirohiko Hohjoh, Yuchio Yanagawa, Toshikazu Shinba, Masayuki Itoh, Kenji Nakamura, Yu-ichi Got. Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice. Human molecular genetics. vol 18. issue 19. 2009-11-09. PMID:19605412. |
arx (the aristaless-related homeobox gene) is a transcription factor that participates in the development of gabaergic and cholinergic neurons in the forebrain. |
2009-11-09 |
2023-08-12 |
mouse |
| Kunio Kitamura, Yukiko Itou, Masako Yanazawa, Maki Ohsawa, Rika Suzuki-Migishima, Yuko Umeki, Hirohiko Hohjoh, Yuchio Yanagawa, Toshikazu Shinba, Masayuki Itoh, Kenji Nakamura, Yu-ichi Got. Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice. Human molecular genetics. vol 18. issue 19. 2009-11-09. PMID:19605412. |
both types of mutant mice exhibited the mutation-specific lesser presence of gabaergic and cholinergic neurons in the striatum, medial septum and ventral forebrain nuclei when compared with wild-type mice. |
2009-11-09 |
2023-08-12 |
mouse |
| K G Commons, M R Seroc. Coincidence of neurokinin 1 receptor with the vesicular glutamate transporter 3 (VGLUT3) in the rat forebrain. Neuroscience letters. vol 464. issue 3. 2009-11-09. PMID:19699779. |
the third vesicular glutamate transporter (vglut3) is expressed in a subset of cholinergic and gabaergic neurons in the forebrain. |
2009-11-09 |
2023-08-12 |
rat |
| Theodore A Slotkin, Ian T Ryde, Nicola Wrench, Jennifer A Card, Frederic J Seidle. Nonenzymatic role of acetylcholinesterase in neuritic sprouting: regional changes in acetylcholinesterase and choline acetyltransferase after neonatal 6-hydroxydopamine lesions. Neurotoxicology and teratology. vol 31. issue 3. 2009-09-16. PMID:19452616. |
parallel examinations of choline acetyltransferase, an enzymatic marker for cholinergic nerve terminals, showed a different pattern of 6-ohda-induced alterations, with initial decreases in both forebrain and brainstem in males and regression toward normal by pn21; females were far less affected. |
2009-09-16 |
2023-08-12 |
rat |
| Martin A Bruno, Wanda C Leon, Gabriela Fragoso, Walter E Mushynski, Guillermina Almazan, A Claudio Cuell. Amyloid beta-induced nerve growth factor dysmetabolism in Alzheimer disease. Journal of neuropathology and experimental neurology. vol 68. issue 8. 2009-09-01. PMID:19606067. |
the effects of amyloid-beta amyloid cns burden on ngf metabolism may explain the paradoxical upregulation of pro-ngf in ad accompanied by atrophy of forebrain cholinergic neurons. |
2009-09-01 |
2023-08-12 |
mouse |
| Debora Cutuli, Francesca Foti, Laura Mandolesi, Paola De Bartolo, Francesca Gelfo, Francesca Federico, Laura Petrosin. Cognitive performances of cholinergically depleted rats following chronic donepezil administration. Journal of Alzheimer's disease : JAD. vol 17. issue 1. 2009-08-12. PMID:19221411. |
since acute and chronic administration of the acetylcholinesterase inhibitors, namely donepezil, improves cognitive functions in patients afflicted by mild to moderate dementia and reverses memory deficits in experimental models of learning and memory, it seemed interesting to assess the effects of chronic donepezil treatment on cognitive functions in adult rats with forebrain cholinergic depletion. |
2009-08-12 |
2023-08-12 |
rat |
| S Trifonov, T Houtani, S Hamada, M Kase, M Maruyama, T Sugimot. In situ hybridization study of the distribution of choline acetyltransferase mRNA and its splice variants in the mouse brain and spinal cord. Neuroscience. vol 159. issue 1. 2009-06-25. PMID:19162134. |
on the other hand, r3, r4 and n1 splice variants revealed a moderate to high level of expression in the brainstem motor and autonomic nuclei and ventral and lateral horns of the spinal cord compared to a low expression level in forebrain cholinergic structures. |
2009-06-25 |
2023-08-12 |
mouse |
| Dhakshin Ramanathan, Mark H Tuszynski, James M Conne. The basal forebrain cholinergic system is required specifically for behaviorally mediated cortical map plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 18. 2009-05-28. PMID:19420265. |
these results dissociate the contribution of cholinergic mechanisms to distinct forms of cortical plasticity and support the hypothesis that the forebrain cholinergic system is selectively required for modulating complex forms of cortical plasticity driven by behavioral experience. |
2009-05-28 |
2023-08-12 |
Not clear |
| A Fragkouli, V Pachnis, F Stylianopoulo. Sex differences in water maze performance and cortical neurotrophin levels of LHX7 null mutant mice. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19095044. |
mice lacking both alleles of the lim-homeobox gene lhx7 display dramatically reduced number of forebrain cholinergic neurons. |
2009-05-20 |
2023-08-12 |
mouse |
| A Fragkouli, V Pachnis, F Stylianopoulo. Sex differences in water maze performance and cortical neurotrophin levels of LHX7 null mutant mice. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19095044. |
given the fact that sex differences are consistently observed in forebrain cholinergic function, in the present study we investigated whether the absence of lhx7 differentially affects water maze performance in the two sexes. |
2009-05-20 |
2023-08-12 |
mouse |
| R Jazi, R Lalonde, S Qian, C Straziell. Regional brain evaluation of acetylcholinesterase activity in PS1/A246E transgenic mice. Neuroscience research. vol 63. issue 2. 2009-03-17. PMID:19056437. |
forebrain cholinergic innervation was estimated in transgenic mice with the a246e mutation by measuring the activity of the non-specific catabolic enzyme, acetylcholinesterase (ache). |
2009-03-17 |
2023-08-12 |
mouse |
| R Jazi, R Lalonde, S Qian, C Straziell. Regional brain evaluation of acetylcholinesterase activity in PS1/A246E transgenic mice. Neuroscience research. vol 63. issue 2. 2009-03-17. PMID:19056437. |
as the murine model caused no apparent learning defects, cholinergic network changes in forebrain seem to be an early event caused by soluble abeta peptides. |
2009-03-17 |
2023-08-12 |
mouse |
| Mylène Fréchette, Kerry Rennie, Bruce A Pappa. Developmental forebrain cholinergic lesion and environmental enrichment: behaviour, CA1 cytoarchitecture and neurogenesis. Brain research. vol 1252. 2009-02-27. PMID:19084506. |
developmental forebrain cholinergic lesion and environmental enrichment: behaviour, ca1 cytoarchitecture and neurogenesis. |
2009-02-27 |
2023-08-12 |
rat |