| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A C Cuello, M A Bruno, K F S Bel. NGF-cholinergic dependency in brain aging, MCI and Alzheimer's disease. Current Alzheimer research. vol 4. issue 4. 2008-02-01. PMID:17908036. |
forebrain cholinergic neurons are highly dependent on nerve growth factor (ngf) for phenotype maintenance. |
2008-02-01 |
2023-08-12 |
mouse |
| O V Dovhan', V O Maĭs'kyĭ, O I Piliavs'kyĭ, A V Maznychenk. [NADPH-diaphorase neurons and their interrelationship with microvascular vessels in the basal forebrain limbic structures and hypothalamus]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 53. issue 5. 2008-01-11. PMID:18080492. |
these areas largely overlap with the cholinergic ch1-ch4 forebrain system of the rodent brain. |
2008-01-11 |
2023-08-12 |
rat |
| Jeffrey G Edwards, Ann Greig, Yoko Sakata, Dimitry Elkin, William C Miche. Cholinergic innervation of the zebrafish olfactory bulb. The Journal of comparative neurology. vol 504. issue 6. 2008-01-04. PMID:17722029. |
a number of fish species receive forebrain cholinergic input but two recent reports failed to find evidence of cholinergic cell bodies or fibers in the olfactory bulbs (obs) of zebrafish. |
2008-01-04 |
2023-08-12 |
zebrafish |
| Hiroki Yamamoto, Jo Kitawaki, Noriko Kikuchi, Tomoharu Okubo, Koichi Iwasa, Mitsuhiro Kawata, Hideo Honj. Effects of estrogens on cholinergic neurons in the rat basal nucleus. The Journal of steroid biochemistry and molecular biology. vol 107. issue 1-2. 2007-12-27. PMID:17651965. |
these results suggest that e(2) and j 861 have positive effects on cholinergic neurons that project from the basal nucleus to the forebrain cortex. |
2007-12-27 |
2023-08-12 |
rat |
| J Espallergues, P Lapalud, A Christopoulos, V A Avlani, P M Sexton, A Vamvakides, T Mauric. Involvement of the sigma1 (sigma1) receptor in the anti-amnesic, but not antidepressant-like, effects of the aminotetrahydrofuran derivative ANAVEX1-41. British journal of pharmacology. vol 152. issue 2. 2007-12-18. PMID:17641675. |
the sigma (1) receptor modulates glutamatergic and cholinergic responses in the forebrain and selective agonists are potent anti-amnesic and antidepressant drugs. |
2007-12-18 |
2023-08-12 |
Not clear |
| Sylvia E Perez, Saleem Dar, Milos D Ikonomovic, Steven T DeKosky, Elliott J Mufso. Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse. Neurobiology of disease. vol 28. issue 1. 2007-12-12. PMID:17662610. |
cholinergic forebrain degeneration in the appswe/ps1deltae9 transgenic mouse. |
2007-12-12 |
2023-08-12 |
mouse |
| Sylvia E Perez, Saleem Dar, Milos D Ikonomovic, Steven T DeKosky, Elliott J Mufso. Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse. Neurobiology of disease. vol 28. issue 1. 2007-12-12. PMID:17662610. |
these results suggest that abeta deposition has age-dependent effects on cortical and hippocampal chat fiber networks and enzyme activity, but does not impact the survival of cholinergic intrinsic or long projection forebrain neurons in appswe/ps1deltae9 tg mice. |
2007-12-12 |
2023-08-12 |
mouse |
| Qiang Liu, Jie W. Neuronal nicotinic acetylcholine receptors serve as sensitive targets that mediate beta-amyloid neurotoxicity. Acta pharmacologica Sinica. vol 27. issue 10. 2007-12-11. PMID:17007734. |
alzheimer's disease (ad) is the most common form of brain dementia characterized by the accumulation of beta-amyloid peptides (abeta) and loss of forebrain cholinergic neurons. |
2007-12-11 |
2023-08-12 |
Not clear |
| E T Ang, F Gomez-Pinill. Potential therapeutic effects of exercise to the brain. Current medicinal chemistry. vol 14. issue 24. 2007-11-28. PMID:17979709. |
ngf and bdnf) and their receptors, some pro-inflammatory cytokines (l-1beta, il-6, tnf-alpha, ifn-gamma), microglia and astrocytes, and the cholinergic neuronal cells in the forebrain. |
2007-11-28 |
2023-08-12 |
Not clear |
| Santina Chiechio, Agata Copani, Robert W Gereau, Ferdinando Nicolett. Acetyl-L-carnitine in neuropathic pain: experimental data. CNS drugs. vol 21 Suppl 1. 2007-10-17. PMID:17696591. |
these processes involve the activation of muscarinic cholinergic receptors in the forebrain, and an increased expression of type-2 metabotropic glutamate (mglu2) receptors in dorsal root ganglia neurons. |
2007-10-17 |
2023-08-12 |
Not clear |
| James H Chin, Li Ma, David MacTavish, Jack H Jhamanda. Amyloid beta protein modulates glutamate-mediated neurotransmission in the rat basal forebrain: involvement of presynaptic neuronal nicotinic acetylcholine and metabotropic glutamate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 35. 2007-09-25. PMID:17728440. |
glutamatergic miniature epscs (mepscs) were recorded using whole-cell patch-clamp recordings from identified cholinergic dbb neurons in rat forebrain slices. |
2007-09-25 |
2023-08-12 |
rat |
| V Sposato, L Manni, G N Chaldakov, L Alo. Streptozotocin-induced diabetes is associated with changes in NGF levels in pancreas and brain. Archives italiennes de biologie. vol 145. issue 2. 2007-08-21. PMID:17639781. |
ngf plays an important role during brain development and may be able to delay or even reverse damaged forebrain cholinergic neurons that undergo degeneration in aged animals and in alzheimer's disease (ad). |
2007-08-21 |
2023-08-12 |
rat |
| Alexandre Antonio Vieira, Eduardo Colombari, Laurival A De Luca, Débora Simões de Almeida Colombari, José V Menan. Central cholinergic blockade reduces the pressor response to L-glutamate into the rostral ventrolateral medullary pressor area. Brain research. vol 1155. 2007-08-13. PMID:17493593. |
the results suggest that cholinergic mechanisms probably from forebrain facilitate or modulate the pressor responses to l-glu into the rvlm. |
2007-08-13 |
2023-08-12 |
rat |
| A Claudio Cuello, Martin A Brun. The failure in NGF maturation and its increased degradation as the probable cause for the vulnerability of cholinergic neurons in Alzheimer's disease. Neurochemical research. vol 32. issue 6. 2007-08-01. PMID:17404842. |
this short review discusses the arguments to consider the dismetabolism of the pathway responsible for both the maturation and degradation of ngf as the culprit of vulnerability of the forebrain cholinergic system to the alzheimer's disease neuropathology. |
2007-08-01 |
2023-08-12 |
Not clear |
| A Claudio Cuello, Martin A Brun. The failure in NGF maturation and its increased degradation as the probable cause for the vulnerability of cholinergic neurons in Alzheimer's disease. Neurochemical research. vol 32. issue 6. 2007-08-01. PMID:17404842. |
this metabolic scenario in alzheimer's disease should result in the failure of ngf trophic support to forebrain cholinergic neurons and thus explaining the vulnerability of these neurons in this neurodegenerative condition. |
2007-08-01 |
2023-08-12 |
Not clear |
| Xiangdong Hua, Ming Lei, Yongjie Zhang, Jiong Ding, Qunying Han, Gang Hu, Ming Xia. Long-term D-galactose injection combined with ovariectomy serves as a new rodent model for Alzheimer's disease. Life sciences. vol 80. issue 20. 2007-06-25. PMID:17391708. |
this was accompanied by cholinergic neuronal loss in the forebrain and synaptic degeneration in the hippocampus and cerebral cortex which was not observed in intact controls, animals receiving injections of d-gal alone, untreated ovx animals or ovx animals receiving both d-gal and 17-beta estradiol. |
2007-06-25 |
2023-08-12 |
rat |
| Mitsuru Sanada, Fang Zheng, Tobias Huth, Christian Alzheime. Cholinergic modulation of periaqueductal grey neurons: does it contribute to epileptogenesis after organophosphorus nerve agent intoxication? Toxicology. vol 233. issue 1-3. 2007-05-29. PMID:16996672. |
previous work has shown that a single focal microinjection of the unselective cholinergic agonist, carbachol, into the periaqueductal grey (pag) of the midbrain is sufficient to induce forebrain seizures in rats. |
2007-05-29 |
2023-08-12 |
rat |
| b' S Pirondi, G D\'Intino, M Gusciglio, A Massella, L Giardino, E Kuteeva, S-O Ogren, T H\\xc3\\xb6kfelt, L Calz\\xc3\\xa. Changes in brain cholinergic markers and spatial learning in old galanin-overexpressing mice. Brain research. vol 1138. 2007-05-21. PMID:17266943.' |
the cholinergic forebrain system is involved in learning and memory, and its age-dependent decline correlates with a decrease in cognitive performance. |
2007-05-21 |
2023-08-12 |
mouse |
| Lisa M Savage, Jessica Roland, Anna Klintsov. Selective septohippocampal - but not forebrain amygdalar - cholinergic dysfunction in diencephalic amnesia. Brain research. vol 1139. 2007-05-08. PMID:17289001. |
selective septohippocampal - but not forebrain amygdalar - cholinergic dysfunction in diencephalic amnesia. |
2007-05-08 |
2023-08-12 |
rat |
| M Dumont, R Lalonde, J-F Ghersi-Egea, K Fukuchi, C Straziell. Regional acetylcholinesterase activity and its correlation with behavioral performances in 15-month old transgenic mice expressing the human C99 fragment of APP. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 9. 2007-05-02. PMID:16362638. |
in the present investigation, the cholinergic innervation in forebrain regions of transgenic mice (tg13592) expressing the human betaapp c99 fragment was compared to that of non-transgenic controls by measuring the activity of the non-specific catabolic enzyme, acetylcholinesterase (ache). |
2007-05-02 |
2023-08-12 |
mouse |