| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Mitchelso. Differentiation between the actions of acetylcholine and tetramethylammonium on the isolated taenia of the guinea-pig caecum by hemicholinium-3. British journal of pharmacology. vol 42. issue 1. 1971-07-27. PMID:4325608. |
edrophonium, in concentrations which preferentially inhibit acetylcholinesterase, increased contractions produced by acetylcholine and converted responses to nicotine or transmural stimulation into contractions or biphasic responses with a marked contraction phase but did not increase contractions produced by tma.6. |
1971-07-27 |
2023-08-11 |
Not clear |
| F Mitchelso. Differentiation between the actions of acetylcholine and tetramethylammonium on the isolated taenia of the guinea-pig caecum by hemicholinium-3. British journal of pharmacology. vol 42. issue 1. 1971-07-27. PMID:4325608. |
iso-ompa, in concentrations which preferentially inhibit butyrylcholinesterase, had no effect on responses to acetylcholine, nicotine, transmural stimulation or tma.7. |
1971-07-27 |
2023-08-11 |
Not clear |
| J D Graham, A Suhaila, A Ta. Response to acetylcholine and nicotine of the perfused vessels of the rabbit ear. British journal of pharmacology. vol 41. issue 3. 1971-07-06. PMID:5576256. |
response to acetylcholine and nicotine of the perfused vessels of the rabbit ear. |
1971-07-06 |
2023-08-11 |
rabbit |
| M E Holman, T C Muir, J H Szurszewski, K Yonemur. Effect of iontophoretic application of cholinergic agonists and their antagonists to guinea-pig pelvic ganglia. British journal of pharmacology. vol 41. issue 1. 1971-04-26. PMID:5547760. |
iontophoretic application of nicotine (nic) and acetylcholine (ach) reduced membrane resistance and caused a depolarization which in approximately 80% of cells led to the firing of action potentials. |
1971-04-26 |
2023-08-11 |
Not clear |
| P J Watso. Drug receptor sites in the rabbit saphenous nerve. British journal of pharmacology. vol 40. issue 1. 1971-02-04. PMID:4395078. |
the actions of acetylcholine, carbachol, methacholine, pilocarpine, nicotine, tetramethylammonium, 1,1-dimethyl-4-phenylpiperazinium, histamine, 5-hydroxytryptamine, angiotensin, bradykinin and potassium chloride were investigated on the sensory endings of the rabbit saphenous nerve.2. |
1971-02-04 |
2023-08-11 |
rabbit |
| J P Finberg, W S Pear. Function of smooth muscle of the rat renal pelvis--response of the isolated pelvis muscle to angiotensin and some other substances. British journal of pharmacology. vol 39. issue 2. 1970-08-17. PMID:4316596. |
acetylcholine, nicotine and 5-hydroxytryptamine had no effect on the isolated tissue, but isoprenaline was capable of causing a decrease, and tyramine an increase, in the rate of spontaneous contractions in high dose (0.33 mug/ml).5. |
1970-08-17 |
2023-08-11 |
rat |
| C Chothia, P Paulin. The conformation of cholinergic molecules at nicotinic nerve receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 65. issue 3. 1970-07-06. PMID:5267133. |
a correlation of the crystal structure analyses of the potent nicotinic agonists acetylcholine, acetyl-alpha-methylcholine, lactoylcholine, 1,1-dimethyl-4-phenylpiperazine, and nicotine allows one to determine the conformation of cholinergic agonists relevant to nicotinic nerve receptors. |
1970-07-06 |
2023-08-11 |
Not clear |
| A A Nikulin, Iu F Krylo. [Effect of adrenaline, acetylcholine, nicotine, pentamine and histamine on blood pressure in rabbits with an experimentally induced hypercholesteremia and following ionizing radiation]. Radiobiologiia. vol 8. issue 4. 1970-07-02. PMID:5757441. |
[effect of adrenaline, acetylcholine, nicotine, pentamine and histamine on blood pressure in rabbits with an experimentally induced hypercholesteremia and following ionizing radiation]. |
1970-07-02 |
2023-08-12 |
Not clear |
| J Christense. Pharmacologic identification of the lower esophageal sphincter. The Journal of clinical investigation. vol 49. issue 4. 1970-06-22. PMID:5443171. |
isometric contractions of strips from the distal 6 cm were recorded in vitro in response to acetylcholine, carbachol, methacholine, nicotine. |
1970-06-22 |
2023-08-11 |
Not clear |
| F H Schneide. Secretion from the cortex-free bovine adrenal medulla. British journal of pharmacology. vol 37. issue 2. 1969-12-18. PMID:5348426. |
catecholamines were secreted from the tissue upon stimulation with carbamylcholine, nicotine sulphate, acetylcholine bromide, histamine dihydrochloride, (+)-amphetamine sulphate and potassium chloride.3. |
1969-12-18 |
2023-08-11 |
cattle |
| I L Natof. The pharmacology of the cholinoceptor in muscle preparations of Ascaris lumbricoides var. suum. British journal of pharmacology. vol 37. issue 1. 1969-12-01. PMID:4390485. |
these drugs were, in descending order of potency: dimethylphenylpiperazinium, nicotine, acetylcholine, carbachol, decamethonium and pyridine-2-aldoxime methiodide.3. |
1969-12-01 |
2023-08-11 |
Not clear |
| A G Parks, D J Fishlock, J D Cameron, H Ma. Preiminary investigation of the pharmacology of the human internal anal sphincter. Gut. vol 10. issue 8. 1969-10-30. PMID:4390257. |
the lower part of the sphincter was generally insensitive to acetylcholine and nicotine whereas the upper part of the sphincter contracted with acetylcholine and regularly relaxed with nicotine. |
1969-10-30 |
2023-08-11 |
human |
| P J Bernard, Y Piette, A L Delaunois, A F De Schaepdryve. Action of topically applied atropine, eserine, acetylcholine and nicotine on cortical epilepsy in the rabbit. Archives internationales de pharmacodynamie et de therapie. vol 177. issue 2. 1969-10-21. PMID:5807180. |
action of topically applied atropine, eserine, acetylcholine and nicotine on cortical epilepsy in the rabbit. |
1969-10-21 |
2023-08-12 |
rabbit |
| R D O'Brien, L P Gilmou. A muscarone-binding material in electroplax and its relation to the acetylcholine receptor. I. Centrifugal assay. Proceedings of the National Academy of Sciences of the United States of America. vol 63. issue 2. 1969-09-29. PMID:5257140. |
the material behaves in several ways as one would expect of the binding component of the acetylcholine receptor, especially in its high affinity for muscarone (approximate k = 7 x 10(-6)m), acetylcholine (approximate k = 1.1 x 10(-6)m), curare, and nicotine, and its insensitivity to noncholinergic agents; the reversibility of its muscarone binding; and its suitably small amount (about 1.8 nmole/gm). |
1969-09-29 |
2023-08-11 |
Not clear |
| F Hobbiger, F Mitchelson, M J Ran. The actions of some cholinomimetic drugs on the isolated taenia of the guinea-pig caecum. British journal of pharmacology. vol 36. issue 1. 1969-06-26. PMID:4388770. |
the actions on the taenia of 4-(m-chlorophenylcarbamoyloxy)-2-butynyl-trimethylammonium chloride (mcn-a-343), n-benzyl-3-pyrrolidyl acetate methobromide (ahr-602), tetramethylammonium (tma) and choline phenyl ether have been examined and compared with the actions of acetylcholine, nicotine and 1,1-dimethyl-4-phenylpiperazinium (dmpp).2. |
1969-06-26 |
2023-08-11 |
Not clear |
| F Hobbiger, F Mitchelson, M J Ran. The actions of some cholinomimetic drugs on the isolated taenia of the guinea-pig caecum. British journal of pharmacology. vol 36. issue 1. 1969-06-26. PMID:4388770. |
acetylcholine, mcn-a-343 and ahr-602 produced only contractions; tma produced contractions or biphasic responses; and choline phenyl ether, nicotine and dmpp produced contractions, relaxations or biphasic responses.4. |
1969-06-26 |
2023-08-11 |
Not clear |
| D A Brow. Responses of normal and denervated cat superior cervical ganglia to some stimulant compounds. The Journal of physiology. vol 201. issue 1. 1969-04-26. PMID:5773557. |
nictitating membrane recording suggested that denervation increased the response of the ganglion to acetylcholine, but had little effect on ganglionic sensitivities to carbachol, nicotine, tetramethylammonium or potassium chloride.5. |
1969-04-26 |
2023-08-12 |
cat |
| A K Armitage, G H Hall, C M Seller. Effects of nicotine on electrocortical activity and acetylcholine release from the cat cerebral cortex. British journal of pharmacology. vol 35. issue 1. 1969-02-17. PMID:5762038. |
effects of nicotine on electrocortical activity and acetylcholine release from the cat cerebral cortex. |
1969-02-17 |
2023-08-12 |
cat |
| A K Armitage, G H Hall, C M Seller. Effects of nicotine on electrocortical activity and acetylcholine release from the cat cerebral cortex. British journal of pharmacology. vol 35. issue 1. 1969-02-17. PMID:5762038. |
the effects of small amounts of nicotine on electrocortical activity and central acetylcholine (ach) release have been studied on anaesthetized cats.2. |
1969-02-17 |
2023-08-12 |
cat |
| b' S M Chittal, N K Dadkar, B B Gaitond\\xc3\\xa. Interactions between acetylcholine, 5-hydroxytryptamine, nicotine and morphine on isolated rabbit atria. British journal of pharmacology. vol 34. issue 1. 1968-11-01. PMID:4386371.' |
interactions between acetylcholine, 5-hydroxytryptamine, nicotine and morphine on isolated rabbit atria. |
1968-11-01 |
2023-08-11 |
rabbit |