| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Tse, N L Brackett, J F Ku. Alterations in activities of cyclic nucleotide systems and in beta-adrenergic receptor-mediated activation of cyclic AMP-dependent protein kinase during progression and regression of isoproterenol-induced cardiac hypertrophy. Biochimica et biophysica acta. vol 542. issue 3. 1978-12-02. PMID:210840. |
initial and transient increases in the basal levels of cyclic gmp in the heart were noted prior to cardiac hypertrophy in rats administered isoproterenol. |
1978-12-02 |
2023-08-11 |
rat |
| J Tse, N L Brackett, J F Ku. Alterations in activities of cyclic nucleotide systems and in beta-adrenergic receptor-mediated activation of cyclic AMP-dependent protein kinase during progression and regression of isoproterenol-induced cardiac hypertrophy. Biochimica et biophysica acta. vol 542. issue 3. 1978-12-02. PMID:210840. |
in cardiac hypertrophy, the maximal activity ratio(--cyclic amp/+cyclic amp) of cyclic amp-dependent protein kinase in the incubated minced heart caused by isoproterenol was lower, whereas the concentration of isoproterenol required to increase the activity ratio half-maximally was higher than controls; the reduced responsiveness to the drug, however, was reversed when the hypertrophy regressed. |
1978-12-02 |
2023-08-11 |
rat |
| J Tse, N L Brackett, J F Ku. Alterations in activities of cyclic nucleotide systems and in beta-adrenergic receptor-mediated activation of cyclic AMP-dependent protein kinase during progression and regression of isoproterenol-induced cardiac hypertrophy. Biochimica et biophysica acta. vol 542. issue 3. 1978-12-02. PMID:210840. |
these observations, taken collectively, appear to suggest that the desensitization of the beta-adrenergic mechanism seen in the cardiac hypertrophy produced by repeated administration of isoproterenol is associated with adaptive modifications in certain parameters of the cyclic nucleotide systems. |
1978-12-02 |
2023-08-11 |
rat |
| J Szabó, K Nosztray, A Szöö. Studies on adenosine triphosphatase activity of rat cardiac myosin in isoproterenol-induced cardiac hypertrophy. Acta biologica Academiae Scientiarum Hungaricae. vol 28. issue 4. 1978-11-18. PMID:211764. |
cardiac hypertrophy was induced by isoproterenol treatment. |
1978-11-18 |
2023-08-11 |
rat |
| B Feiglin, P C Read. Protein and DNA levels in the submandibular salivary glands of isoproterenol stimulated mice. The Australian journal of experimental biology and medical science. vol 56. issue 1. 1978-09-01. PMID:666669. |
the dna and soluble and sedimental protein levels were studied in isoproterenol stimulated mouse submandibular salivary glands over a period of 200 h. hypertrophy, the predominant cellular phenomenon following chronic isoproterenol treatment, was associated with a marked elevation of 14c-leucine incorporation into the buffer soluble protein fraction and a less pronounced isotope incorporation into the sedimental sub-cellular fraction as well as continued dna synthesis. |
1978-09-01 |
2023-08-11 |
mouse |
| J Chubb, R Huxtabl. The effects of isoproterenol on taurine concentration in the rat heart. European journal of pharmacology. vol 48. issue 4. 1978-07-24. PMID:148363. |
the doses of isoproterenol employed induced cardiac hypertrophy, but the stimulation of taurine influx appeared to be an independent phenomenon, in that near maximum stimulation of influx was achieved prior to stimulation of ornithine decarboxylase activity. |
1978-07-24 |
2023-08-11 |
rat |
| R Ensslen, F Schwarz, J Thormann, M Schleppe. [Left ventricular ejection and ejection reserve during isoproterenol infusion in hypertrophic obstructive cardiomyopathy (author's transl)]. Zeitschrift fur Kardiologie. vol 66. issue 11. 1978-02-18. PMID:145761. |
[left ventricular ejection and ejection reserve during isoproterenol infusion in hypertrophic obstructive cardiomyopathy (author's transl)]. |
1978-02-18 |
2023-08-11 |
Not clear |
| R Ensslen, F Schwarz, J Thormann, M Schleppe. [Left ventricular ejection and ejection reserve during isoproterenol infusion in hypertrophic obstructive cardiomyopathy (author's transl)]. Zeitschrift fur Kardiologie. vol 66. issue 11. 1978-02-18. PMID:145761. |
in 10 patients with hypertrophic obstructive cardiomyopathy (hocm) and in 10 patients without heart disease (normals) left ventricular function and myocardial reserve under isoproterenol (iso) infusion (0.3 microgram/kg b.w./min) were measured. |
1978-02-18 |
2023-08-11 |
Not clear |
| T Barka, G T Burk. Secretory behaviour of hypertrophic and hyperplastic salivary gland. The Histochemical journal. vol 9. issue 4. 1977-12-29. PMID:914652. |
the enzyme content and the secretory behaviour of normal rat salivary glands were compared with these properties in glands made hypertrophic and hyperplastic by the chronic administration of isoproterenol. |
1977-12-29 |
2023-08-11 |
rat |
| b' A Iazigian, E Lapohos, S Szab\\xc3\\xb. Protein fractions and antigens of the heart muscle in isoproterenol induced cardiac hypertrophy. Archives roumaines de pathologie experimentales et de microbiologie. vol 35. issue 4. 1977-11-30. PMID:143922.' |
protein fractions and antigens of the heart muscle in isoproterenol induced cardiac hypertrophy. |
1977-11-30 |
2023-08-11 |
Not clear |
| J Szabó, L Csáky, J Szeg. Experimental cardiac hypertrophy induced by isoproterenol in the rat. Acta physiologica Academiae Scientiarum Hungaricae. vol 46. issue 3. 1977-11-25. PMID:143367. |
experimental cardiac hypertrophy induced by isoproterenol in the rat. |
1977-11-25 |
2023-08-11 |
rat |
| F Cantalamessa, G De Caro, P C Federici, M Perfumi, P Palatron. [Effects of the oligo-mineral-chloride-bicarbonate-alkaline-sulphureous "S. Rocco di Tolentino" water on salivary glands hypertrophy induced in the rat by isoproterenol (author's transl)]. L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma. vol 48. issue 2. 1977-09-17. PMID:883998. |
[effects of the oligo-mineral-chloride-bicarbonate-alkaline-sulphureous "s. rocco di tolentino" water on salivary glands hypertrophy induced in the rat by isoproterenol (author's transl)]. |
1977-09-17 |
2023-08-11 |
rat |
| H G Zimmer, E Gerlac. Changes of myocardial adenine nucleotide and protein synthesis during development of cardiac hypertrophy. Basic research in cardiology. vol 72. issue 2-3. 1977-06-30. PMID:140670. |
studies on three models of cardiac hypertrophy (aortic constriction, application of isoproterenol, daily administrations of 3,3'5-triiodo-l-thyronine, respectively) reveal that the enhancement of de novo synthesis of adenine nucleotides occurs very early during the development of cardiac hypertorphy and always precedes the increase of protein synthesis. |
1977-06-30 |
2023-08-11 |
Not clear |
| G Gerzeli, S Barn. Modifications in some rat liver cell components following stimulation with isoprenaline (a cytospectrophotometric, microrefractometric and cytoelectrophoretic study). Rivista di istochimica, normale e patologica. vol 20. issue 1-3. 1977-06-11. PMID:1030832. |
several cytochemical and cytophysical techniques (cytospectrophotometry, microrefractometry, and cytoelectrophoresis) were employed for elucidating the effects on the stimulation of the liver cell with high doses of isoprenaline, an amine which is known to produce hypertrophy and hyperplasia in various organs with effects also at the genetic and metabolic level. |
1977-06-11 |
2023-08-11 |
rat |
| S L Spector, M Garza Gome. Dose-response effects of albuterol aerosol compared with isoproterenol and placebo aerosols: response to albuterol, isoproterenol, and placebo aerosols. The Journal of allergy and clinical immunology. vol 59. issue 4. 1977-05-27. PMID:321502. |
in addition albuterol was successfully used by a patient with idiopathic hypertrophic subaortic stenosis who was unable to tolerate isoproterenol, as well as by some patients with idiosyncratic responses to isoproterenol; a few patients appeared to derive little benefit from either albuterol or isoproterenol. |
1977-05-27 |
2023-08-11 |
Not clear |
| L Vulimiri, M C Linder, H N Munr. Sex difference in distribution and iron responsiveness of the two ferritins of rat cardiac and skeletal muscle. Biochimica et biophysica acta. vol 497. issue 1. 1977-05-27. PMID:849483. |
induction of cardiac connective tissue hypertrophy with isoproterenol inverted the ratio of slow to fast ferritin in female rats, while iron administration along with isoproterenol restored this to normal. |
1977-05-27 |
2023-08-11 |
rat |
| M Fukushima, T Bark. The effects of 5-bromodeoxyuridine and isoproterenol on the postnatal differentiation of rat submandibular gland. The American journal of anatomy. vol 147. issue 2. 1976-12-01. PMID:970350. |
pretreatment with brdu partially inhibited the effects of isoproterenol on differentiation and hypertrophy of the submandibular gland. |
1976-12-01 |
2023-08-11 |
rat |
| A Baskervill. The development and persistence of bronchialgland hypertrophy and goblet-cell hyperplasia in the pig after injection of isoprenaline. The Journal of pathology. vol 119. issue 1. 1976-08-23. PMID:932872. |
the development and persistence of bronchialgland hypertrophy and goblet-cell hyperplasia in the pig after injection of isoprenaline. |
1976-08-23 |
2023-08-11 |
Not clear |
| E Rau, D K Meye. A diurnal rhythm of incorporation of L-[3H] leucine in myocardium of the rat. Recent advances in studies on cardiac structure and metabolism. vol 7. 1976-08-02. PMID:131959. |
analysis of ventricular weight to body weight ratio indicates that isoproterenol was a more effective stimulus of hypertrophy if given during the dark period, when the rat is most active, than when administered during the light hours. |
1976-08-02 |
2023-08-11 |
rat |
| Y Deshaies, J LeBlanc, J Willemo. Studies on protein metabolism during isoproterenol-induced cardiac hypertrophy. Recent advances in studies on cardiac structure and metabolism. vol 8. 1976-04-10. PMID:129835. |
chronic treatment with isoproterenol (iso) (30 mug/100 g body wt/day for 21 days) causes a hypertrophy of the heart (approximately 40%). |
1976-04-10 |
2023-08-11 |
rat |