| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Deshaies, J Willemot, J Leblan. Protein synthesis, amino acid uptake, and pools during isoproterenol-induced hypertrophy of the rat heart and tibialis muscle. Canadian journal of physiology and pharmacology. vol 59. issue 2. 1981-07-09. PMID:6452942. |
chronic administration of isoproterenol (iso) produces hypertrophy of the rat heart and tibialis muscle. |
1981-07-09 |
2023-08-12 |
rat |
| W H Newman, D M Elliso. A differential effect of ouabain and beta-agonists on contractility and lactic acid production in the hypertrophied heart. European journal of pharmacology. vol 68. issue 4. 1981-05-26. PMID:6110553. |
in response to norepinephrine or isoproterenol, dogs with pressure overload cardiac hypertrophy showed depressed contractility and myocardial lactic acid production when compared to normal dogs. |
1981-05-26 |
2023-08-12 |
Not clear |
| H G Zimmer, E Gerlac. Early metabolic alterations during the development of experimentally induced cardiac hypertrophy. Arzneimittel-Forschung. vol 30. issue 11a. 1981-05-13. PMID:6452127. |
the main biochemical features of protein synthesis in the myocardium are described as well as several metabolic alterations that occur during the very early stages in three models of cardiac hypertrophy resulting from pressure overload in vivo and in vitro, application of a high dose of isoprenaline and repeated daily administration of triiodothyronine. |
1981-05-13 |
2023-08-12 |
Not clear |
| M Tanaka, Y Tsuchihashi, H Katsume, H Ijichi, Y Ibat. Comparison of cardiac lesions induced in rats by isoproterenol and by repeated stress of restraint and water immersion with special reference to etiology of cardiomyopathy. Japanese circulation journal. vol 44. issue 12. 1981-02-26. PMID:6255219. |
1) cardiac lesions induced by isoproterenol, characteristic findings of which were myocardial hypertrophy, myocardial degeneration and myocardial necrosis replaced by interstitial fibrosis, were more analogous to cardiomyopathy than myocardial infarction or cardiac hypertrophy. |
1981-02-26 |
2023-08-12 |
rat |
| M Tanaka, Y Tsuchihashi, H Katsume, H Ijichi, Y Ibat. Comparison of cardiac lesions induced in rats by isoproterenol and by repeated stress of restraint and water immersion with special reference to etiology of cardiomyopathy. Japanese circulation journal. vol 44. issue 12. 1981-02-26. PMID:6255219. |
2) cardiac lesions induced by repeated stress of restraint and water immersion, characteristic findings of which were myocardial hypertrophy, myocardial degeneration and myocardial necrosis replaced by interstitial fibrosis, were similar to those induced by isoproterenol. |
1981-02-26 |
2023-08-12 |
rat |
| H G Zimmer, H Ibel, E Gerlac. Significance of the hexose monophosphate shunt in experimentally induced cardiac hypertrophy. Basic research in cardiology. vol 75. issue 1. 1980-08-15. PMID:6155904. |
in three models of cardiac hypertrophy in rats (aortic constriction, application of a single dose of isoproterenol and daily injections of triiodothyronine) the biosynthesis of myocardial adenine nucleotides was enhanced. |
1980-08-15 |
2023-08-12 |
rat |
| C P Adler, W Sandritte. Alterations of substances (DNA, myoglobin, myosin, protein) in experimentally induced cardiac hypertrophy and under the influence of drugs (isoproterenol, cytostatics, strophanthin). Basic research in cardiology. vol 75. issue 1. 1980-08-15. PMID:6446283. |
alterations of substances (dna, myoglobin, myosin, protein) in experimentally induced cardiac hypertrophy and under the influence of drugs (isoproterenol, cytostatics, strophanthin). |
1980-08-15 |
2023-08-12 |
Not clear |
| W H Newman, J G Web. Adaptation of left ventricle to chronic pressure overload: response to inotropic drugs. The American journal of physiology. vol 238. issue 2. 1980-05-14. PMID:6444783. |
the cf response to isoproterenol and calcium was depressed in dogs with hypertrophy; however, the cf response to ouabain was not different from control. |
1980-05-14 |
2023-08-12 |
Not clear |
| N W Revis, A J Camero. Association of myocardial cell necrosis with experimental cardiac hypertrophy. The Journal of pathology. vol 128. issue 4. 1980-03-17. PMID:160447. |
cardiac hypertrophy was induced in rabbits by injecting thyroxine or isoprenaline, or by surgically constricting the abdominal aorta. |
1980-03-17 |
2023-08-11 |
Not clear |
| C J Lima. Increased number of beta-adrenergic receptors in the hypertrophied myocardium. Biochimica et biophysica acta. vol 588. issue 1. 1980-01-28. PMID:227473. |
a biochemical basis for these changes is provided by the observation that the number of cardiac beta-adrenergic receptors - as reflected in specific [3h]dihydroalprenolol binding - is increased in hypertrophy without a change in the affinity of dihydroalprenolol for the binding sites or in the capacity of isoproterenol to displace dihydroalprenolol. |
1980-01-28 |
2023-08-11 |
Not clear |
| J F David, D Barth. [Some experimental evidences for immune functions of interstitial plasma-cells of the submaxillary glands (author's transl)]. Archives d'anatomie, d'histologie et d'embryologie normales et experimentales. vol 61. 1979-12-18. PMID:386952. |
they do not show any change in case of hypertrophy of the salivary glands which is observed under isoproterenol repeated administration. |
1979-12-18 |
2023-08-11 |
human |
| J Muenzer, C Bildstein, M Gleason, D M Carlso. Purification of proline-rich proteins from parotid glands of isoproterenol-treated rats. The Journal of biological chemistry. vol 254. issue 13. 1979-09-01. PMID:447672. |
prolonged isoproterenol treatment of rats is known to cause hypertrophy and hyperplasia of the parotid glands. |
1979-09-01 |
2023-08-11 |
rat |
| N W Revis, A J Camero. Metabolism of lipids in experimental hypertrophic hearts of rabbits. Metabolism: clinical and experimental. vol 28. issue 6. 1979-08-16. PMID:156300. |
cardiac hypertrophy was induced in rabbits by subcutaneous injection of thyroxine or isoprenaline or by surgically constricting the abdominal aorta. |
1979-08-16 |
2023-08-11 |
Not clear |
| N W Revis, A J Camero. The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits. Cardiovascular research. vol 12. issue 6. 1978-12-29. PMID:151586. |
cardiac hypertrophy was induced in rabbits by injecting either thyroxine or isoprenaline or by surgically constricting the abdominal aorta. |
1978-12-29 |
2023-08-11 |
Not clear |
| J Tse, N L Brackett, J F Ku. Alterations in activities of cyclic nucleotide systems and in beta-adrenergic receptor-mediated activation of cyclic AMP-dependent protein kinase during progression and regression of isoproterenol-induced cardiac hypertrophy. Biochimica et biophysica acta. vol 542. issue 3. 1978-12-02. PMID:210840. |
initial and transient increases in the basal levels of cyclic gmp in the heart were noted prior to cardiac hypertrophy in rats administered isoproterenol. |
1978-12-02 |
2023-08-11 |
rat |
| J Tse, N L Brackett, J F Ku. Alterations in activities of cyclic nucleotide systems and in beta-adrenergic receptor-mediated activation of cyclic AMP-dependent protein kinase during progression and regression of isoproterenol-induced cardiac hypertrophy. Biochimica et biophysica acta. vol 542. issue 3. 1978-12-02. PMID:210840. |
in cardiac hypertrophy, the maximal activity ratio(--cyclic amp/+cyclic amp) of cyclic amp-dependent protein kinase in the incubated minced heart caused by isoproterenol was lower, whereas the concentration of isoproterenol required to increase the activity ratio half-maximally was higher than controls; the reduced responsiveness to the drug, however, was reversed when the hypertrophy regressed. |
1978-12-02 |
2023-08-11 |
rat |
| J Tse, N L Brackett, J F Ku. Alterations in activities of cyclic nucleotide systems and in beta-adrenergic receptor-mediated activation of cyclic AMP-dependent protein kinase during progression and regression of isoproterenol-induced cardiac hypertrophy. Biochimica et biophysica acta. vol 542. issue 3. 1978-12-02. PMID:210840. |
these observations, taken collectively, appear to suggest that the desensitization of the beta-adrenergic mechanism seen in the cardiac hypertrophy produced by repeated administration of isoproterenol is associated with adaptive modifications in certain parameters of the cyclic nucleotide systems. |
1978-12-02 |
2023-08-11 |
rat |
| J Szabó, K Nosztray, A Szöö. Studies on adenosine triphosphatase activity of rat cardiac myosin in isoproterenol-induced cardiac hypertrophy. Acta biologica Academiae Scientiarum Hungaricae. vol 28. issue 4. 1978-11-18. PMID:211764. |
cardiac hypertrophy was induced by isoproterenol treatment. |
1978-11-18 |
2023-08-11 |
rat |
| B Feiglin, P C Read. Protein and DNA levels in the submandibular salivary glands of isoproterenol stimulated mice. The Australian journal of experimental biology and medical science. vol 56. issue 1. 1978-09-01. PMID:666669. |
the dna and soluble and sedimental protein levels were studied in isoproterenol stimulated mouse submandibular salivary glands over a period of 200 h. hypertrophy, the predominant cellular phenomenon following chronic isoproterenol treatment, was associated with a marked elevation of 14c-leucine incorporation into the buffer soluble protein fraction and a less pronounced isotope incorporation into the sedimental sub-cellular fraction as well as continued dna synthesis. |
1978-09-01 |
2023-08-11 |
mouse |
| J Chubb, R Huxtabl. The effects of isoproterenol on taurine concentration in the rat heart. European journal of pharmacology. vol 48. issue 4. 1978-07-24. PMID:148363. |
the doses of isoproterenol employed induced cardiac hypertrophy, but the stimulation of taurine influx appeared to be an independent phenomenon, in that near maximum stimulation of influx was achieved prior to stimulation of ornithine decarboxylase activity. |
1978-07-24 |
2023-08-11 |
rat |