| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Harri, P Kuusela, R Oksanen-Ross. Modification of training-induced responses by repeated norepinephrine injections in rats. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 53. issue 3. 1982-12-18. PMID:7129988. |
changes observable in all treated rat groups included reduced weight gain, reduced food intake, decreased amount of epididymal fat, hypertrophy of the heart and adrenals, and increased tail skin temperature response to isoproterenol (0.2 mg/kg sc). |
1982-12-18 |
2023-08-12 |
rat |
| M Harri, P Kuusela, R Oksanen-Ross. Modification of training-induced responses by repeated norepinephrine injections in rats. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 53. issue 3. 1982-12-18. PMID:7129988. |
the changes produced by repeated norepinephrine injections alone (hypertrophy of the brown adipose tissue and increased colonic temperature response to isoproterenol) failed to develop if the rats underwent physical training in addition to drug treatment. |
1982-12-18 |
2023-08-12 |
rat |
| H Hashimoto, K Ogaw. Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis. Japanese heart journal. vol 22. issue 4. 1982-01-09. PMID:6272002. |
prophylactic effects of sulfinpyrazone (100 mg/kg), aspirin (5 mg/kg, 50 mg/kg), and propranolol (2 mg/kg, 10 mg/kg) on myocardial necrosis and hypertrophy induced by isoproterenol were examined. |
1982-01-09 |
2023-08-12 |
rat |
| H Hashimoto, K Ogaw. Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis. Japanese heart journal. vol 22. issue 4. 1982-01-09. PMID:6272002. |
premedication of sulfinpyrazone and propranolol significantly preserved myocardial ck activity and decreased cardiac hypertrophy compared with control group (24 hours after isoproterenol injection) while aspirin did not have such effects. |
1982-01-09 |
2023-08-12 |
rat |
| H Hashimoto, K Ogaw. Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis. Japanese heart journal. vol 22. issue 4. 1982-01-09. PMID:6272002. |
it was concluded that premedication of sulfinpyrazone and propranolol reduce cardiac necrosis and hypertrophy induced by isoproterenol, but aspirin did not have such cardioprotective effects. |
1982-01-09 |
2023-08-12 |
rat |
| M Manohar, G E Bisgard, V Bullard, J H Ranki. Blood flow in the hypertrophied right ventricular myocardium of unanesthetized ponies. The American journal of physiology. vol 240. issue 6. 1981-08-27. PMID:6454349. |
to examine the effects of right ventricular (rv) hypertrophy on regional myocardial blood flow and coronary vascular reserve, hemodynamics and myocardial blood flow (15-micrometers radio-nuclide-labeled microspheres) were studied in 12 unanesthetized adult ponies before and during intravenous isoproterenol hcl infusion (1 microgram.kg-1.min-1). |
1981-08-27 |
2023-08-12 |
Not clear |
| Y Deshaies, J Willemot, J Leblan. Protein synthesis, amino acid uptake, and pools during isoproterenol-induced hypertrophy of the rat heart and tibialis muscle. Canadian journal of physiology and pharmacology. vol 59. issue 2. 1981-07-09. PMID:6452942. |
chronic administration of isoproterenol (iso) produces hypertrophy of the rat heart and tibialis muscle. |
1981-07-09 |
2023-08-12 |
rat |
| W H Newman, D M Elliso. A differential effect of ouabain and beta-agonists on contractility and lactic acid production in the hypertrophied heart. European journal of pharmacology. vol 68. issue 4. 1981-05-26. PMID:6110553. |
in response to norepinephrine or isoproterenol, dogs with pressure overload cardiac hypertrophy showed depressed contractility and myocardial lactic acid production when compared to normal dogs. |
1981-05-26 |
2023-08-12 |
Not clear |
| H G Zimmer, E Gerlac. Early metabolic alterations during the development of experimentally induced cardiac hypertrophy. Arzneimittel-Forschung. vol 30. issue 11a. 1981-05-13. PMID:6452127. |
the main biochemical features of protein synthesis in the myocardium are described as well as several metabolic alterations that occur during the very early stages in three models of cardiac hypertrophy resulting from pressure overload in vivo and in vitro, application of a high dose of isoprenaline and repeated daily administration of triiodothyronine. |
1981-05-13 |
2023-08-12 |
Not clear |
| M Tanaka, Y Tsuchihashi, H Katsume, H Ijichi, Y Ibat. Comparison of cardiac lesions induced in rats by isoproterenol and by repeated stress of restraint and water immersion with special reference to etiology of cardiomyopathy. Japanese circulation journal. vol 44. issue 12. 1981-02-26. PMID:6255219. |
1) cardiac lesions induced by isoproterenol, characteristic findings of which were myocardial hypertrophy, myocardial degeneration and myocardial necrosis replaced by interstitial fibrosis, were more analogous to cardiomyopathy than myocardial infarction or cardiac hypertrophy. |
1981-02-26 |
2023-08-12 |
rat |
| M Tanaka, Y Tsuchihashi, H Katsume, H Ijichi, Y Ibat. Comparison of cardiac lesions induced in rats by isoproterenol and by repeated stress of restraint and water immersion with special reference to etiology of cardiomyopathy. Japanese circulation journal. vol 44. issue 12. 1981-02-26. PMID:6255219. |
2) cardiac lesions induced by repeated stress of restraint and water immersion, characteristic findings of which were myocardial hypertrophy, myocardial degeneration and myocardial necrosis replaced by interstitial fibrosis, were similar to those induced by isoproterenol. |
1981-02-26 |
2023-08-12 |
rat |
| H G Zimmer, H Ibel, E Gerlac. Significance of the hexose monophosphate shunt in experimentally induced cardiac hypertrophy. Basic research in cardiology. vol 75. issue 1. 1980-08-15. PMID:6155904. |
in three models of cardiac hypertrophy in rats (aortic constriction, application of a single dose of isoproterenol and daily injections of triiodothyronine) the biosynthesis of myocardial adenine nucleotides was enhanced. |
1980-08-15 |
2023-08-12 |
rat |
| C P Adler, W Sandritte. Alterations of substances (DNA, myoglobin, myosin, protein) in experimentally induced cardiac hypertrophy and under the influence of drugs (isoproterenol, cytostatics, strophanthin). Basic research in cardiology. vol 75. issue 1. 1980-08-15. PMID:6446283. |
alterations of substances (dna, myoglobin, myosin, protein) in experimentally induced cardiac hypertrophy and under the influence of drugs (isoproterenol, cytostatics, strophanthin). |
1980-08-15 |
2023-08-12 |
Not clear |
| W H Newman, J G Web. Adaptation of left ventricle to chronic pressure overload: response to inotropic drugs. The American journal of physiology. vol 238. issue 2. 1980-05-14. PMID:6444783. |
the cf response to isoproterenol and calcium was depressed in dogs with hypertrophy; however, the cf response to ouabain was not different from control. |
1980-05-14 |
2023-08-12 |
Not clear |
| N W Revis, A J Camero. Association of myocardial cell necrosis with experimental cardiac hypertrophy. The Journal of pathology. vol 128. issue 4. 1980-03-17. PMID:160447. |
cardiac hypertrophy was induced in rabbits by injecting thyroxine or isoprenaline, or by surgically constricting the abdominal aorta. |
1980-03-17 |
2023-08-11 |
Not clear |
| C J Lima. Increased number of beta-adrenergic receptors in the hypertrophied myocardium. Biochimica et biophysica acta. vol 588. issue 1. 1980-01-28. PMID:227473. |
a biochemical basis for these changes is provided by the observation that the number of cardiac beta-adrenergic receptors - as reflected in specific [3h]dihydroalprenolol binding - is increased in hypertrophy without a change in the affinity of dihydroalprenolol for the binding sites or in the capacity of isoproterenol to displace dihydroalprenolol. |
1980-01-28 |
2023-08-11 |
Not clear |
| J F David, D Barth. [Some experimental evidences for immune functions of interstitial plasma-cells of the submaxillary glands (author's transl)]. Archives d'anatomie, d'histologie et d'embryologie normales et experimentales. vol 61. 1979-12-18. PMID:386952. |
they do not show any change in case of hypertrophy of the salivary glands which is observed under isoproterenol repeated administration. |
1979-12-18 |
2023-08-11 |
human |
| J Muenzer, C Bildstein, M Gleason, D M Carlso. Purification of proline-rich proteins from parotid glands of isoproterenol-treated rats. The Journal of biological chemistry. vol 254. issue 13. 1979-09-01. PMID:447672. |
prolonged isoproterenol treatment of rats is known to cause hypertrophy and hyperplasia of the parotid glands. |
1979-09-01 |
2023-08-11 |
rat |
| N W Revis, A J Camero. Metabolism of lipids in experimental hypertrophic hearts of rabbits. Metabolism: clinical and experimental. vol 28. issue 6. 1979-08-16. PMID:156300. |
cardiac hypertrophy was induced in rabbits by subcutaneous injection of thyroxine or isoprenaline or by surgically constricting the abdominal aorta. |
1979-08-16 |
2023-08-11 |
Not clear |
| N W Revis, A J Camero. The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits. Cardiovascular research. vol 12. issue 6. 1978-12-29. PMID:151586. |
cardiac hypertrophy was induced in rabbits by injecting either thyroxine or isoprenaline or by surgically constricting the abdominal aorta. |
1978-12-29 |
2023-08-11 |
Not clear |