| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Severson, B Anderso. Chronic antidepressant treatment and mouse brain 3H-imipramine binding. Journal of neuroscience research. vol 16. issue 2. 1986-11-20. PMID:3020258. |
haloperidol pretreatment resulted in an increase in the density of striatal d-2 dopamine receptors, but did not alter the density of cerebral cortical 3h-imipramine binding sites or beta-adrenergic receptors. |
1986-11-20 |
2023-08-11 |
mouse |
| T Arima, N Samura, Y Nomura, T Segaw. Comparison of effects of tiapride and sulpiride on D-1, D-2, D-3 and D-4 subtypes of dopamine receptors in rat striatal and bovine caudate nucleus membranes. Japanese journal of pharmacology. vol 41. issue 3. 1986-11-20. PMID:3761757. |
to determine the affinity of tiapride to d-1, d-2, d-3 and d-4 subtypes of dopamine (da) receptors, inhibitory effects of tiapride on [3h]-cis-flupenthixol, [3h]spiperone and [3h]n-propylapomorphine binding were examined in the rat striatum and bovine caudate nucleus membranes and compared to those of sulpiride and haloperidol. |
1986-11-20 |
2023-08-11 |
rat |
| L H Tecott, L L Kwong, S Uhr, S J Peroutk. Differential modulation of dopamine D2 receptors by chronic haloperidol, nitrendipine, and pimozide. Biological psychiatry. vol 21. issue 12. 1986-11-14. PMID:2428411. |
differential modulation of dopamine d2 receptors by chronic haloperidol, nitrendipine, and pimozide. |
1986-11-14 |
2023-08-11 |
rat |
| L H Tecott, L L Kwong, S Uhr, S J Peroutk. Differential modulation of dopamine D2 receptors by chronic haloperidol, nitrendipine, and pimozide. Biological psychiatry. vol 21. issue 12. 1986-11-14. PMID:2428411. |
administration, haloperidol significantly increases (p less than 0.01) dopamine d2 receptor binding to 123% +/- 6% of control values, whereas pimozide treatment significantly reduces (p less than 0.001) striatal 3h-spiperone binding to 46% +/- 6% of control values. |
1986-11-14 |
2023-08-11 |
rat |
| K Kamata, A Sugimoto, T Kameyam. Effect of chronic haloperidol on dopamine release following microinjection of GABA into the substantia nigra zona reticulata in the rat. Brain research. vol 380. issue 1. 1986-11-13. PMID:3756464. |
effect of chronic haloperidol on dopamine release following microinjection of gaba into the substantia nigra zona reticulata in the rat. |
1986-11-13 |
2023-08-11 |
rat |
| C J de Graaf, J Kor. Conditional tolerance to haloperidol-induced catalepsy is not caused by striatal dopamine receptor supersensitivity. Psychopharmacology. vol 90. issue 1. 1986-11-12. PMID:3094062. |
the purpose of this study was to determine if non-pharmacological stimuli influence behavioural tolerance to haloperidol via striatal postsynaptic dopamine receptors. |
1986-11-12 |
2023-08-11 |
rat |
| J Arita, F Kimur. Characterization of in vitro dopamine synthesis in the median eminence of rats with haloperidol-induced hyperprolactinemia and bromocriptine-induced hypoprolactinemia. Endocrinology. vol 119. issue 4. 1986-10-30. PMID:3019639. |
in order to investigate the mechanism of prl action on dopamine synthesis in tuberoinfundibular dopaminergic (tida) neurons, in vitro dopamine synthesis in the median eminence of hypothalamic slices was compared between hyperprolactinemic and hypoprolactinemic rats, hyper- and hypoprolactinemia were induced in ovariectomized rats by repetitive injections of the dopamine antagonist haloperidol (halo) and the dopamine agonist bromocriptine (bromo), respectively. |
1986-10-30 |
2023-08-11 |
rat |
| A A Grace, B S Bunne. Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording. The Journal of pharmacology and experimental therapeutics. vol 238. issue 3. 1986-10-23. PMID:3746660. |
induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording. |
1986-10-23 |
2023-08-11 |
rat |
| A A Grace, B S Bunne. Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording. The Journal of pharmacology and experimental therapeutics. vol 238. issue 3. 1986-10-23. PMID:3746660. |
acute administration of the antipsychotic drug haloperidol causes an increase in the firing rate and in the proportion of spontaneously active dopamine neurons in the substantia nigra. |
1986-10-23 |
2023-08-11 |
rat |
| A A Grace, B S Bunne. Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording. The Journal of pharmacology and experimental therapeutics. vol 238. issue 3. 1986-10-23. PMID:3746660. |
in contrast, repeated administration of haloperidol for 21 days results in a dramatic decrease in the number of dopamine neurons displaying spontaneous electrophysiological activity. |
1986-10-23 |
2023-08-11 |
rat |
| G J Kilpatrick, N el Tayar, H Van de Waterbeemd, P Jenner, B Testa, C D Marsde. The thermodynamics of agonist and antagonist binding to dopamine D-2 receptors. Molecular pharmacology. vol 30. issue 3. 1986-10-21. PMID:2943980. |
the ability of the dopamine antagonists, haloperidol, cis-flupenthixol, cis-n-(1-benzyl-1-methypyrrolidin-3-yl)-5-chloro-2-methoxy-9- methylaminobenzamide (ym 09151-2), raclopride, and clozapine, and of the agonists apomorphine and pergolide, to compete with [3h]spiperone binding was little altered by temperature. |
1986-10-21 |
2023-08-11 |
rat |
| L Rèny. Ejaculations induced by p-chloroamphetamine in the rat. Neuropharmacology. vol 24. issue 8. 1986-10-21. PMID:3837857. |
the rank order of potency for some dopamine (da) receptor antagonists was chlorpromazine, domperidone, haloperidol, pimozide. |
1986-10-21 |
2023-08-11 |
rat |
| S Li, G Pelletie. The role of dopamine in the control of neuropeptide Y neurons in the rat arcuate nucleus. Neuroscience letters. vol 69. issue 1. 1986-10-20. PMID:3528937. |
in order to determine the role of dopamine (da) on neuropeptide y (npy) neurons in the arcuate nucleus of the rat hypothalamus, we evaluated the effects of alpha-methylparatyrosine (alpha-mpt), an inhibitor of catecholamines biosynthesis, and haloperidol, a dopaminergic antagonist, on npy immunoreactive neurons. |
1986-10-20 |
2023-08-11 |
rat |
| P J Schreur, N F Nichol. Two automated locomotor activity tests for dopamine autoreceptor agonists. Pharmacology, biochemistry, and behavior. vol 25. issue 1. 1986-10-16. PMID:2875471. |
on the other hand, haloperidol hcl, chlorpromazine hcl, and clozapine decreased both amphetamine- and apomorphine-stimulated behavior, suggesting a postsynaptic dopamine antagonism. |
1986-10-16 |
2023-08-11 |
rat |
| G J Treisman, N Muirhead, M E Gneg. Increased sensitivity of adenylate cyclase activity in the striatum of the rat to calmodulin and GppNHp after chronic treatment with haloperidol. Neuropharmacology. vol 25. issue 6. 1986-10-16. PMID:3092124. |
chronic treatment of rats with haloperidol causes behavioral supersensitivity to dopaminergic agonists and an increase in the sensitivity of adenylate cyclase activity in the striatum to stimulation by dopamine. |
1986-10-16 |
2023-08-11 |
rat |
| D K Armstrong, J F Dasta, T E Reilley, R D Tallma. Effect of haloperidol on dopamine-induced increase in renal blood flow. Drug intelligence & clinical pharmacy. vol 20. issue 7-8. 1986-10-10. PMID:3743409. |
this response is mediated in part by stimulation of dopaminergic receptors in the kidney, which could be attenuated by the dopamine blocker haloperidol. |
1986-10-10 |
2023-08-11 |
Not clear |
| D K Armstrong, J F Dasta, T E Reilley, R D Tallma. Effect of haloperidol on dopamine-induced increase in renal blood flow. Drug intelligence & clinical pharmacy. vol 20. issue 7-8. 1986-10-10. PMID:3743409. |
simultaneous administration of haloperidol 50 micrograms/kg iv did not influence the ability of low-dose dopamine to increase rbf. |
1986-10-10 |
2023-08-11 |
Not clear |
| D K Armstrong, J F Dasta, T E Reilley, R D Tallma. Effect of haloperidol on dopamine-induced increase in renal blood flow. Drug intelligence & clinical pharmacy. vol 20. issue 7-8. 1986-10-10. PMID:3743409. |
although haloperidol is an antagonist of dopaminergic receptors, the increase in rbf associated with low-dose dopamine is maintained when intravenous haloperidol is concurrently administered to dogs. |
1986-10-10 |
2023-08-11 |
Not clear |
| R E Hrusk. Hypophysectomy does not alter the increase in striatal dopamine receptor density produced by 6-hydroxydopamine lesions in male rats. Neuroscience letters. vol 68. issue 2. 1986-10-01. PMID:3092152. |
while hypophysectomy can alter the increase in striatal dopamine (da) receptor density observed after estrogen, haloperidol or prolactin treatments, it does not alter the increase in density found after 6-hydroxydopamine lesions of the da neurons in male rats. |
1986-10-01 |
2023-08-11 |
rat |
| P O'Connor, S J Dorison, K J Watling, J E Dowlin. Factors affecting release of 3H-dopamine from perfused carp retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 7. 1986-09-17. PMID:2874198. |
bicuculline and picrotoxin also stimulated an increase in camp accumulation, which was inhibited by the dopamine antagonist haloperidol. |
1986-09-17 |
2023-08-11 |
Not clear |