| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tino Dyhring, Elsebet Ø Nielsen, Clas Sonesson, Fredrik Pettersson, Jonas Karlsson, Peder Svensson, Palle Christophersen, Nicholas Water. The dopaminergic stabilizers pridopidine (ACR16) and (-)-OSU6162 display dopamine D(2) receptor antagonism and fast receptor dissociation properties. European journal of pharmacology. vol 628. issue 1-3. 2010-04-05. PMID:19919834. |
however, the finding that ns30678, which is equipotent to haloperidol and raclopride, also displays fast receptor dissociation, suggests that the agonist-like structural motif of the dopaminergic stabilizers tested is a critical dissociation rate determinant. |
2010-04-05 |
2023-08-12 |
Not clear |
| John Muench, Ann M Hame. Adverse effects of antipsychotic medications. American family physician. vol 81. issue 5. 2010-03-25. PMID:20187598. |
also, as a class, the older first-generation antipsychotics are more likely to be associated with movement disorders, but this is primarily true of medications that bind tightly to dopaminergic neuroreceptors, such as haloperidol, and less true of medications that bind weakly, such as chlorpromazine. |
2010-03-25 |
2023-08-12 |
Not clear |
| Sophie Rémillard, Emmanuelle Pourcher, Henri Cohe. Long-term skill proceduralization in schizophrenia. Journal of the International Neuropsychological Society : JINS. vol 16. issue 1. 2010-03-02. PMID:19900349. |
previous studies had revealed no specific effect under haloperidol (typical) and risperidone (atypical) neuroleptic (nlp) treatments for schizophrenia (sz) on a variety of neurocognitive functions relying on the dopaminergic meso-cortico-limbic system (rémillard et al., 2005, 2008). |
2010-03-02 |
2023-08-12 |
human |
| C Toua, L Brand, M Möller, R A Emsley, B H Harve. The effects of sub-chronic clozapine and haloperidol administration on isolation rearing induced changes in frontal cortical N-methyl-D-aspartate and D1 receptor binding in rats. Neuroscience. vol 165. issue 2. 2010-02-24. PMID:19854242. |
furthermore, at the doses examined, in contrast to haloperidol, clozapine bolsters frontal cortical glutamatergic but stabilizes d(1) dopaminergic pathways in a neurodevelopmental animal model of schizophrenia, possibly explaining the atypical clinical characteristics of this drug. |
2010-02-24 |
2023-08-12 |
rat |
| Carlotta E Duncan, Peter R Schofield, Cynthia Shannon Weicker. K(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. Brain research. vol 1304. 2010-01-28. PMID:19781530. |
k(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. |
2010-01-28 |
2023-08-12 |
mouse |
| Amira Taman, Paula Ribeir. Investigation of a dopamine receptor in Schistosoma mansoni: functional studies and immunolocalization. Molecular and biochemical parasitology. vol 168. issue 1. 2009-10-16. PMID:19545592. |
pharmacological studies showed that the s. mansoni dopamine receptor was inhibited by apomorphine, a classical dopamine agonist, as well as known dopaminergic antagonists, including chlorpromazine, spiperone and haloperidol. |
2009-10-16 |
2023-08-12 |
Not clear |
| Bob Oranje, Christine C Gispen-de Wied, Herman G M Westenberg, Chantal Kemner, Marinus N Verbaten, René S Kah. Haloperidol counteracts the ketamine-induced disruption of processing negativity, but not that of the P300 amplitude. The international journal of neuropsychopharmacology. vol 12. issue 6. 2009-08-18. PMID:19154656. |
the combined effects of haloperidol and ketamine reduced task performance, suggesting that this is dependent on dopaminergic d2 activity, probably in the prefrontal cortex. |
2009-08-18 |
2023-08-12 |
human |
| Quintino M Dias, Simone F Crespilho, João Walter S Silveira, Wiliam A Prad. Muscarinic and alpha(1)-adrenergic mechanisms contribute to the spinal mediation of stimulation-induced antinociception from the pedunculopontine tegmental nucleus in the rat. Pharmacology, biochemistry, and behavior. vol 92. issue 3. 2009-08-05. PMID:19463264. |
mecamylamine, propranolol or haloperidol (non-selective nicotinic cholinergic, beta-adrenergic and dopaminergic antagonists, respectively). |
2009-08-05 |
2023-08-12 |
rat |
| S Desjardins, C Doyen, Y Contejean, K Kaye, P Paube. [Treatment of a serious autistic disorder in a child with Naltrexone in an oral suspension form]. L'Encephale. vol 35. issue 2. 2009-07-07. PMID:19393386. |
the most common medication consists of psychotropic therapies by administration of dopaminergic and/or serotoninergic receptor antagonists (haloperidol, risperidone, clomipramine). |
2009-07-07 |
2023-08-12 |
Not clear |
| Chandra C Cardoso, Kelly R Lobato, Ricardo W Binfaré, Priscilla K Ferreira, Angelo O Rosa, Adair Roberto S Santos, Ana Lúcia S Rodrigue. Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 2. 2009-06-02. PMID:19059299. |
a 5-ht(1a) receptor antagonist), way100635 (0.1 mg/kg, s.c., a selective 5-ht(1a) receptor antagonist), ritanserin (4 mg/kg, i.p., a 5-ht(2a/2c) receptor antagonist), ketanserin (5 mg/kg, a preferential 5-ht(2a) receptor antagonist), prazosin (1 mg/kg, i.p., an alpha(1)-adrenoceptor antagonist), yohimbine (1 mg/kg, i.p., an alpha(2)-adrenoceptor antagonist), haloperidol (0.2 mg/kg, i.p., a non selective dopaminergic receptor antagonist), sch23390 (0.05 mg/kg, s.c., a dopamine d(1) receptor antagonist) or sulpiride (50 mg/kg, i.p., a dopamine d(2) receptor antagonist) 30 min before the administration of magnesium chloride (30 mg/kg, i.p.) |
2009-06-02 |
2023-08-12 |
mouse |
| Carmela Dell'aversano, Carmine Tomasetti, Felice Iasevoli, Andrea de Bartolomei. Antipsychotic and antidepressant co-treatment: effects on transcripts of inducible postsynaptic density genes possibly implicated in behavioural disorders. Brain research bulletin. vol 79. issue 2. 2009-04-28. PMID:19189858. |
in the present study, we evaluated the acute effects of two ssris, citalopram and escitalopram, alone or in combination with haloperidol, on the expression of homer1a together with its splice variant ania-3, and p11, two genes linked respectively to dopaminergic and serotonergic neurotransmission and involved in synaptic plasticity. |
2009-04-28 |
2023-08-12 |
Not clear |
| Carmela Dell'aversano, Carmine Tomasetti, Felice Iasevoli, Andrea de Bartolomei. Antipsychotic and antidepressant co-treatment: effects on transcripts of inducible postsynaptic density genes possibly implicated in behavioural disorders. Brain research bulletin. vol 79. issue 2. 2009-04-28. PMID:19189858. |
these results demonstrated that haloperidol+citalopram combination exerts synergistic effects on homer expression, suggesting that citalopram may influence the impact by haloperidol on the dopaminergic neurotransmission. |
2009-04-28 |
2023-08-12 |
Not clear |
| Liana L Melo, Ellen C H M Pereira, Cássia H Pagini, Norberto C Coimbra, Marcus L Brandão, Elenice A M Ferrar. Effects of microinjections of apomorphine and haloperidol into the inferior colliculus on the latent inhibition of the conditioned emotional response. Experimental neurology. vol 216. issue 1. 2009-03-20. PMID:19084523. |
pe and npe rats received ic microinjections of physiological saline, the dopaminergic agonist apomorphine (9.0 microg/0.5 microl/side), or the dopaminergic antagonist haloperidol (0.5 microg/0.5 microl/side) before both pre-exposure and conditioning. |
2009-03-20 |
2023-08-12 |
rat |
| Farhat Batool, Darakhshan J Halee. Serotonin(1A) receptor agonism in the expression of behavioral dopaminergic supersensitivity in subchronic haloperidol treated rats. Pakistan journal of pharmaceutical sciences. vol 21. issue 4. 2008-12-22. PMID:18930864. |
serotonin(1a) receptor agonism in the expression of behavioral dopaminergic supersensitivity in subchronic haloperidol treated rats. |
2008-12-22 |
2023-08-12 |
rat |
| Janita Turchi, Deanne Buffalari, Mortimer Mishki. Double dissociation of pharmacologically induced deficits in visual recognition and visual discrimination learning. Learning & memory (Cold Spring Harbor, N.Y.). vol 15. issue 8. 2008-11-18. PMID:18685146. |
monkeys trained in either one-trial recognition at 8- to 10-min delays or multi-trial discrimination habits with 24-h intertrial intervals received systemic cholinergic and dopaminergic antagonists, scopolamine and haloperidol, respectively, in separate sessions. |
2008-11-18 |
2023-08-12 |
monkey |
| Peethambaran Arun, Chikkathur N Madhavarao, John R Moffett, Aryan M A Namboodir. Antipsychotic drugs increase N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells. Journal of neurochemistry. vol 106. issue 4. 2008-09-12. PMID:18631215. |
in the present study we have used high performance liquid chromatography to determine the effects of the antipsychotic drugs haloperidol and clozapine on naa and naag levels in sh-sy5y human neuroblastoma cells, a model system used to test the responses of dopaminergic neurons in vitro. |
2008-09-12 |
2023-08-12 |
human |
| Marcelo M S Lima, Monica L Andersen, Angela B Reksidler, Andressa Silva, Adriano Zager, Sílvio M Zanata, Maria A B F Vital, Sergio Tufi. Blockage of dopaminergic D(2) receptors produces decrease of REM but not of slow wave sleep in rats after REM sleep deprivation. Behavioural brain research. vol 188. issue 2. 2008-06-20. PMID:18201777. |
we have hypothesized that dopaminergic d(2) receptor blockage induced by haloperidol could generate a reduction or even an ablation of rapid eye movement (rem) sleep. |
2008-06-20 |
2023-08-12 |
rat |
| Jessica M Castellano, Jody Batrynchuk, Kristine Dolbeare, Vaneeta Verma, Amandeep Mann, Kevin J Skoblenick, Rodney L Johnson, Ram K Mishr. MIF-1 and its peptidomimetic analogs attenuate haloperidol-induced vacuous chewing movements and modulate apomorphine-induced rotational behavior in 6-hydroxydopamine-lesioned rats. Peptides. vol 28. issue 10. 2008-01-22. PMID:17766011. |
two melanocyte-stimulating hormone release inhibiting factor-1 (mif-1) also known as l-prolyl-l-leucyl-glycinamide (plg) peptidomimetic analogs, 3(r)-[[[2(s)-pyrrolidinyl]carbonyl]-amino]-3-(butyl)-2-oxo-1-pyrrolidineacetamide trifluoroacetate (a) and 3(r)-[[[2(s)-pyrrolidinyl]carbonyl]amino]-3-(benzyl)-2-oxo-1-pyrrolidineacetamide trifluoroacetate (b), were evaluated for their ability to modulate dopaminergic activity by measuring apomorphine-induced rotations in 6-hydroxydopamine (6-ohda)-lesioned rats, and haloperidol (hp)-induced vacuous chewing movements (vcms) in rats; animal models of parkinson's disease (pd) and human tardive dyskinesia (td), respectively. |
2008-01-22 |
2023-08-12 |
human |
| C R Chen, W M Qu, M H Qiu, X H Xu, M H Yao, Y Urade, Z L Huan. Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic alpha1 and histaminergic H1 receptors in mice. Neuropharmacology. vol 53. issue 4. 2007-12-20. PMID:17681557. |
the antiepileptic effect in both mes and ptz models was antagonized by the adrenergic alpha(1) receptor antagonist terazosin, but not by the adrenergic alpha(2) receptor antagonist yohimbine or by dopaminergic receptor antagonists, sch-23390 (for d(1) receptors) and haloperidol (for d(2) ones). |
2007-12-20 |
2023-08-12 |
mouse |
| Ashish Dhir, S K Kulkarn. Involvement of dopamine (DA)/serotonin (5-HT)/sigma (sigma) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist. Brain research bulletin. vol 74. issue 1-3. 2007-11-13. PMID:17683790. |
in the fst was reversed by dopaminergic and sigma receptor antagonist, haloperidol (0.5 mg/kg, i.p. |
2007-11-13 |
2023-08-12 |
mouse |