| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarai Hess, Cristina Padoani, Laiana Carla Scorteganha, Iandra Holzmann, Angela Malheiros, Rosendo Augusto Yunes, Franco Delle Monache, Márcia Maria de Souz. Assessment of mechanisms involved in antinociception caused by myrsinoic acid B. Biological & pharmaceutical bulletin. vol 33. issue 2. 2010-09-03. PMID:20118542. |
in contrast, antinociception was not affected by naloxone (non-selective opioid receptor antagonist, 1.0 mg/kg), phaclofen (2.0 mg/kg) and bicuculline (1.0 mg/kg) gaba(b) and gaba(a) receptor antagonists, respectively, ondansetron (0.3 mg/kg) and ketaserin (1.0 mg/kg), (5-ht3 and 5-ht2 receptors, respectively) and haloperidol (0.2 mg/kg), a non-selective dopaminergic receptor. |
2010-09-03 |
2023-08-12 |
mouse |
| Taleen Der-Ghazarian, Sergios Charntikov, Fausto A Varela, Cynthia A Crawford, Sanders A McDougal. Effects of repeated and acute aripiprazole or haloperidol treatment on dopamine synthesis in the dorsal striatum of young rats: comparison to adult rats. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 5. 2010-07-29. PMID:20372943. |
the major findings of this study were that: (a) acute treatment with haloperidol and aripiprazole increased da synthesis while quinpirole reduced it; (b) pretreatment with haloperidol and aripiprazole blunted the synthesis-modulating effects of acutely administered dopaminergic drugs; and (c) da synthesis of young and adult rats was affected in a qualitatively similar manner by da agonist, antagonist, and partial agonist drugs. |
2010-07-29 |
2023-08-12 |
rat |
| José Luis Góngora-Alfar. [Caffeine as a preventive drug for Parkinson's disease: epidemiologic evidence and experimental support]. Revista de neurologia. vol 50. issue 4. 2010-05-18. PMID:20198594. |
recently, it was shown that male rats treated with moderate doses of caffeine (5 mg/kg/day) during six months, followed by a withdrawal period of at least two weeks, developed a greater resistance to the catalepsy induced with the dopaminergic antagonist haloperidol, which was possibly mediated by an increase of dopaminergic transmission in the corpus striatum. |
2010-05-18 |
2023-08-12 |
human |
| Tino Dyhring, Elsebet Ø Nielsen, Clas Sonesson, Fredrik Pettersson, Jonas Karlsson, Peder Svensson, Palle Christophersen, Nicholas Water. The dopaminergic stabilizers pridopidine (ACR16) and (-)-OSU6162 display dopamine D(2) receptor antagonism and fast receptor dissociation properties. European journal of pharmacology. vol 628. issue 1-3. 2010-04-05. PMID:19919834. |
in contrast to the high-affinity typical antipsychotics haloperidol and raclopride, the dopaminergic stabilizers acr16 and (-)-osu6162 both displayed fast dopamine d(2) receptor dissociation properties, a feature that has previously been suggested as a contributing factor to antipsychotic atypicality and attributed mainly to low receptor affinity. |
2010-04-05 |
2023-08-12 |
Not clear |
| Tino Dyhring, Elsebet Ø Nielsen, Clas Sonesson, Fredrik Pettersson, Jonas Karlsson, Peder Svensson, Palle Christophersen, Nicholas Water. The dopaminergic stabilizers pridopidine (ACR16) and (-)-OSU6162 display dopamine D(2) receptor antagonism and fast receptor dissociation properties. European journal of pharmacology. vol 628. issue 1-3. 2010-04-05. PMID:19919834. |
however, the finding that ns30678, which is equipotent to haloperidol and raclopride, also displays fast receptor dissociation, suggests that the agonist-like structural motif of the dopaminergic stabilizers tested is a critical dissociation rate determinant. |
2010-04-05 |
2023-08-12 |
Not clear |
| John Muench, Ann M Hame. Adverse effects of antipsychotic medications. American family physician. vol 81. issue 5. 2010-03-25. PMID:20187598. |
also, as a class, the older first-generation antipsychotics are more likely to be associated with movement disorders, but this is primarily true of medications that bind tightly to dopaminergic neuroreceptors, such as haloperidol, and less true of medications that bind weakly, such as chlorpromazine. |
2010-03-25 |
2023-08-12 |
Not clear |
| Sophie Rémillard, Emmanuelle Pourcher, Henri Cohe. Long-term skill proceduralization in schizophrenia. Journal of the International Neuropsychological Society : JINS. vol 16. issue 1. 2010-03-02. PMID:19900349. |
previous studies had revealed no specific effect under haloperidol (typical) and risperidone (atypical) neuroleptic (nlp) treatments for schizophrenia (sz) on a variety of neurocognitive functions relying on the dopaminergic meso-cortico-limbic system (rémillard et al., 2005, 2008). |
2010-03-02 |
2023-08-12 |
human |
| C Toua, L Brand, M Möller, R A Emsley, B H Harve. The effects of sub-chronic clozapine and haloperidol administration on isolation rearing induced changes in frontal cortical N-methyl-D-aspartate and D1 receptor binding in rats. Neuroscience. vol 165. issue 2. 2010-02-24. PMID:19854242. |
furthermore, at the doses examined, in contrast to haloperidol, clozapine bolsters frontal cortical glutamatergic but stabilizes d(1) dopaminergic pathways in a neurodevelopmental animal model of schizophrenia, possibly explaining the atypical clinical characteristics of this drug. |
2010-02-24 |
2023-08-12 |
rat |
| Carlotta E Duncan, Peter R Schofield, Cynthia Shannon Weicker. K(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. Brain research. vol 1304. 2010-01-28. PMID:19781530. |
k(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. |
2010-01-28 |
2023-08-12 |
mouse |
| Amira Taman, Paula Ribeir. Investigation of a dopamine receptor in Schistosoma mansoni: functional studies and immunolocalization. Molecular and biochemical parasitology. vol 168. issue 1. 2009-10-16. PMID:19545592. |
pharmacological studies showed that the s. mansoni dopamine receptor was inhibited by apomorphine, a classical dopamine agonist, as well as known dopaminergic antagonists, including chlorpromazine, spiperone and haloperidol. |
2009-10-16 |
2023-08-12 |
Not clear |
| Bob Oranje, Christine C Gispen-de Wied, Herman G M Westenberg, Chantal Kemner, Marinus N Verbaten, René S Kah. Haloperidol counteracts the ketamine-induced disruption of processing negativity, but not that of the P300 amplitude. The international journal of neuropsychopharmacology. vol 12. issue 6. 2009-08-18. PMID:19154656. |
the combined effects of haloperidol and ketamine reduced task performance, suggesting that this is dependent on dopaminergic d2 activity, probably in the prefrontal cortex. |
2009-08-18 |
2023-08-12 |
human |
| Quintino M Dias, Simone F Crespilho, João Walter S Silveira, Wiliam A Prad. Muscarinic and alpha(1)-adrenergic mechanisms contribute to the spinal mediation of stimulation-induced antinociception from the pedunculopontine tegmental nucleus in the rat. Pharmacology, biochemistry, and behavior. vol 92. issue 3. 2009-08-05. PMID:19463264. |
mecamylamine, propranolol or haloperidol (non-selective nicotinic cholinergic, beta-adrenergic and dopaminergic antagonists, respectively). |
2009-08-05 |
2023-08-12 |
rat |
| S Desjardins, C Doyen, Y Contejean, K Kaye, P Paube. [Treatment of a serious autistic disorder in a child with Naltrexone in an oral suspension form]. L'Encephale. vol 35. issue 2. 2009-07-07. PMID:19393386. |
the most common medication consists of psychotropic therapies by administration of dopaminergic and/or serotoninergic receptor antagonists (haloperidol, risperidone, clomipramine). |
2009-07-07 |
2023-08-12 |
Not clear |
| Chandra C Cardoso, Kelly R Lobato, Ricardo W Binfaré, Priscilla K Ferreira, Angelo O Rosa, Adair Roberto S Santos, Ana Lúcia S Rodrigue. Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 2. 2009-06-02. PMID:19059299. |
a 5-ht(1a) receptor antagonist), way100635 (0.1 mg/kg, s.c., a selective 5-ht(1a) receptor antagonist), ritanserin (4 mg/kg, i.p., a 5-ht(2a/2c) receptor antagonist), ketanserin (5 mg/kg, a preferential 5-ht(2a) receptor antagonist), prazosin (1 mg/kg, i.p., an alpha(1)-adrenoceptor antagonist), yohimbine (1 mg/kg, i.p., an alpha(2)-adrenoceptor antagonist), haloperidol (0.2 mg/kg, i.p., a non selective dopaminergic receptor antagonist), sch23390 (0.05 mg/kg, s.c., a dopamine d(1) receptor antagonist) or sulpiride (50 mg/kg, i.p., a dopamine d(2) receptor antagonist) 30 min before the administration of magnesium chloride (30 mg/kg, i.p.) |
2009-06-02 |
2023-08-12 |
mouse |
| Carmela Dell'aversano, Carmine Tomasetti, Felice Iasevoli, Andrea de Bartolomei. Antipsychotic and antidepressant co-treatment: effects on transcripts of inducible postsynaptic density genes possibly implicated in behavioural disorders. Brain research bulletin. vol 79. issue 2. 2009-04-28. PMID:19189858. |
in the present study, we evaluated the acute effects of two ssris, citalopram and escitalopram, alone or in combination with haloperidol, on the expression of homer1a together with its splice variant ania-3, and p11, two genes linked respectively to dopaminergic and serotonergic neurotransmission and involved in synaptic plasticity. |
2009-04-28 |
2023-08-12 |
Not clear |
| Carmela Dell'aversano, Carmine Tomasetti, Felice Iasevoli, Andrea de Bartolomei. Antipsychotic and antidepressant co-treatment: effects on transcripts of inducible postsynaptic density genes possibly implicated in behavioural disorders. Brain research bulletin. vol 79. issue 2. 2009-04-28. PMID:19189858. |
these results demonstrated that haloperidol+citalopram combination exerts synergistic effects on homer expression, suggesting that citalopram may influence the impact by haloperidol on the dopaminergic neurotransmission. |
2009-04-28 |
2023-08-12 |
Not clear |
| Liana L Melo, Ellen C H M Pereira, Cássia H Pagini, Norberto C Coimbra, Marcus L Brandão, Elenice A M Ferrar. Effects of microinjections of apomorphine and haloperidol into the inferior colliculus on the latent inhibition of the conditioned emotional response. Experimental neurology. vol 216. issue 1. 2009-03-20. PMID:19084523. |
pe and npe rats received ic microinjections of physiological saline, the dopaminergic agonist apomorphine (9.0 microg/0.5 microl/side), or the dopaminergic antagonist haloperidol (0.5 microg/0.5 microl/side) before both pre-exposure and conditioning. |
2009-03-20 |
2023-08-12 |
rat |
| Farhat Batool, Darakhshan J Halee. Serotonin(1A) receptor agonism in the expression of behavioral dopaminergic supersensitivity in subchronic haloperidol treated rats. Pakistan journal of pharmaceutical sciences. vol 21. issue 4. 2008-12-22. PMID:18930864. |
serotonin(1a) receptor agonism in the expression of behavioral dopaminergic supersensitivity in subchronic haloperidol treated rats. |
2008-12-22 |
2023-08-12 |
rat |
| Janita Turchi, Deanne Buffalari, Mortimer Mishki. Double dissociation of pharmacologically induced deficits in visual recognition and visual discrimination learning. Learning & memory (Cold Spring Harbor, N.Y.). vol 15. issue 8. 2008-11-18. PMID:18685146. |
monkeys trained in either one-trial recognition at 8- to 10-min delays or multi-trial discrimination habits with 24-h intertrial intervals received systemic cholinergic and dopaminergic antagonists, scopolamine and haloperidol, respectively, in separate sessions. |
2008-11-18 |
2023-08-12 |
monkey |
| Peethambaran Arun, Chikkathur N Madhavarao, John R Moffett, Aryan M A Namboodir. Antipsychotic drugs increase N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells. Journal of neurochemistry. vol 106. issue 4. 2008-09-12. PMID:18631215. |
in the present study we have used high performance liquid chromatography to determine the effects of the antipsychotic drugs haloperidol and clozapine on naa and naag levels in sh-sy5y human neuroblastoma cells, a model system used to test the responses of dopaminergic neurons in vitro. |
2008-09-12 |
2023-08-12 |
human |