| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katherine M Serafine, Maria A Briscione, Anthony L Rile. The effects of haloperidol on cocaine-induced conditioned taste aversions. Physiology & behavior. vol 105. issue 5. 2012-08-15. PMID:22212241. |
in order to investigate a possible dopaminergic role in cocaine-induced ctas using procedures that circumvented these possible issues, the present series of investigations assessed the aversive effects of the da antagonist haloperidol alone (experiment 1) and in combination with cocaine (experiment 2). |
2012-08-15 |
2023-08-12 |
Not clear |
| Katherine M Serafine, Maria A Briscione, Anthony L Rile. The effects of haloperidol on cocaine-induced conditioned taste aversions. Physiology & behavior. vol 105. issue 5. 2012-08-15. PMID:22212241. |
haloperidol, at doses that were determined to be non-aversive, yet behaviorally active in a locomotor assessment, attenuated cocaine-induced taste aversions, suggesting that cocaine's aversive effects are mediated in part by dopaminergic activity. |
2012-08-15 |
2023-08-12 |
Not clear |
| Aurelia Ces, David Reiss, Ondine Walter, Jürgen Wichmann, Eric P Prinssen, Brigitte L Kieffer, Abdel-Mouttalib Ouagazza. Activation of nociceptin/orphanin FQ peptide receptors disrupts visual but not auditory sensorimotor gating in BALB/cByJ mice: comparison to dopamine receptor agonists. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 2. 2012-04-17. PMID:21881568. |
finally, coadministration of the typical antipsychotic, haloperidol, attenuated ppi impairment induced by ro64-6198, revealing involvement of a dopaminergic component. |
2012-04-17 |
2023-08-12 |
mouse |
| Patrícia Nardin, Ana Carolina Tramontina, André Quincozes-Santos, Lucas S Tortorelli, Paula Lunardi, Paulo R Klein, Krista M Wartchow, Larissa D Bobermin, Carmem Gottfried, Elaine Elisabetsky, Carlos-Alberto Gonçalve. In vitro S100B secretion is reduced by apomorphine: effects of antipsychotics and antioxidants. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 5. 2012-01-19. PMID:21513766. |
we investigated s100b secretion in three different rat brain preparations (fresh hippocampal slices, c6 glioma cells and primary astrocyte cultures) exposed to apomorphine and antipsychotics (haloperidol and risperidone), aiming to evaluate, ex vivo and in vitro, whether dopamine activation and dopaminergic antagonists modulate astroglial activation, as measured by changes in the extracellular levels of s100b. |
2012-01-19 |
2023-08-12 |
rat |
| C K Young, I Q Whishaw, B H Blan. Posterior hypothalamic nucleus deep brain stimulation restores locomotion in rats with haloperidol-induced akinesia but not skilled forelimb use in pellet reaching and lever pressing. Neuroscience. vol 192. 2012-01-18. PMID:21723925. |
recent studies have shown that electrical stimulation of the posterior hypothalamic nucleus (ph) facilitates locomotion in control rats, and rats were made akinetic by dopaminergic blockade via haloperidol or dopamine depletion by the neurotoxin 6-hydroxydopamine. |
2012-01-18 |
2023-08-12 |
rat |
| Thomas C Farrell, Clinton L Cario, Chiara Milanese, Andreas Vogt, Jong-Hyeon Jeong, Edward A Burto. Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models. Neurobiology of disease. vol 44. issue 1. 2011-12-01. PMID:21669287. |
suppression of endogenous dopaminergic signaling by exposure to mpp(+), haloperidol or chlorpromazine reduced mean velocity by decreasing the frequency with which spontaneous movements were initiated, but did not alter active velocity. |
2011-12-01 |
2023-08-12 |
human |
| Stefanie Dedeurwaerdere, Cindy Wintmolders, Greet Vanhoof, Xavier Langloi. Patterns of brain glucose metabolism induced by phosphodiesterase 10A inhibitors in the mouse: a potential translational biomarker. The Journal of pharmacology and experimental therapeutics. vol 339. issue 1. 2011-11-22. PMID:21742809. |
moreover, we could differentiate pde10a inhibitors from haloperidol based on specific patterns of hypermetabolism probably caused by its combined action at both direct and indirect dopaminergic pathways. |
2011-11-22 |
2023-08-12 |
mouse |
| Hiroshi Onogi, Osamu Nakagawasai, Atsushi Sato, Satoru Mitazaki, Kota Nakaya, Kenya Watanabe, Fukie Niijima-Yaoita, Koichi Tan-No, Yuichiro Arai, Tsuneaki Kikuchi, Takeshi Tadan. p-Hydroxyamphetamine causes prepulse inhibition disruption in mice: contribution of serotonin neurotransmission. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21689684. |
administration of p-oha dose-dependently induces prepulse inhibition (ppi) disruption in mice, which is attenuated by pretreatment with haloperidol, clozapine or several dopaminergic agents. |
2011-11-21 |
2023-08-12 |
mouse |
| Tomohiko Fukuda, Hirokazu Hashimoto, Natsumi Okayasu, Akihiko Kameyama, Hiroshi Onogi, Osamu Nakagawasai, Takahiro Nakazawa, Tomoyo Kurosawa, Yan Hao, Tomoya Isaji, Takeshi Tadano, Hisashi Narimatsu, Naoyuki Taniguchi, Jianguo G. Alpha1,6-fucosyltransferase-deficient mice exhibit multiple behavioral abnormalities associated with a schizophrenia-like phenotype: importance of the balance between the dopamine and serotonin systems. The Journal of biological chemistry. vol 286. issue 21. 2011-07-28. PMID:21471224. |
likewise, treatment with haloperidol, which is an antipsychotic drug that antagonizes dopaminergic and serotonergic receptors, significantly reduced hopping behaviors. |
2011-07-28 |
2023-08-12 |
mouse |
| Joachim Perera, Joon Heng Tan, S Jeevathayaparan, Srikumar Chakravarthi, Nagaraja Haleagrahar. Neuroprotective effects of alpha lipoic Acid on haloperidol-induced oxidative stress in the rat brain. Cell & bioscience. vol 1. issue 1. 2011-07-14. PMID:21711768. |
haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. |
2011-07-14 |
2023-08-12 |
rat |
| Randi Oppermann Moe, Janicke Nordgreen, Andrew M Janczak, Berry M Spruijt, Lubor Kostal, Eystein Skjerve, Adroaldo J Zanella, Morten Bakke. Effects of haloperidol, a dopamine D2-like receptor antagonist, on reward-related behaviors in laying hens. Physiology & behavior. vol 102. issue 3-4. 2011-05-25. PMID:21163277. |
in order to investigate the involvement of dopaminergic transmission in the regulation of reward-related behaviors in laying hens, the effects of systemic injections of dopamine d2-like receptor antagonist haloperidol (0.3, 0.5, 1.0 and 2.0 mg/kg s.c.) 30 min prior to a conditioned cue signaling a reward were tested and compared to the effects of a saline injection. |
2011-05-25 |
2023-08-12 |
Not clear |
| Juliano C Capra, Mauricio P Cunha, Daniele G Machado, Andrea D E Zomkowski, Beatriz G Mendes, Adair Roberto S Santos, Moacir G Pizzolatti, Ana Lúcia S Rodrigue. Antidepressant-like effect of scopoletin, a coumarin isolated from Polygala sabulosa (Polygalaceae) in mice: evidence for the involvement of monoaminergic systems. European journal of pharmacology. vol 643. issue 2-3. 2010-12-28. PMID:20599906. |
the pretreatment of mice with ketanserin (5mg/kg, i.p., a preferential 5-ht(2a) receptor antagonist), prazosin (1mg/kg, i.p., an alpha(1)-adrenoceptor antagonist), yohimbine (1mg/kg, i.p., an alpha(2)-adrenoceptor antagonist), haloperidol (0.2mg/kg, i.p., a dopaminergic receptor antagonist), sch23390 (0.05 mg/kg, s.c., a dopamine d(1) receptor antagonist) or sulpiride (50mg/kg, i.p., a dopamine d(2) receptor antagonist), but not way100635 (0.1mg/kg, s.c., a selective 5-ht(1a) receptor antagonist) prevented the antidepressant-like effect of scopoletin (10mg/kg, p.o.) |
2010-12-28 |
2023-08-12 |
mouse |
| Juan Andrés Abin-Carriquiry, Jessika Urbanavicius, Cecilia Scorza, Marcos Rebolledo-Fuentes, Susan Wonnacott, Bruce K Cassels, Federico Daja. Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats. European journal of pharmacology. vol 634. issue 1-3. 2010-11-01. PMID:20184877. |
we studied the role of the dopaminergic system by co-administration of the d2 dopamine receptor antagonist, haloperidol. |
2010-11-01 |
2023-08-12 |
rat |
| Janita Turchi, Bryan Devan, Pingbo Yin, Emmalynn Sigrist, Mortimer Mishki. Pharmacological evidence that both cognitive memory and habit formation contribute to within-session learning of concurrent visual discriminations. Neuropsychologia. vol 48. issue 8. 2010-10-13. PMID:20144631. |
consistent with this dissociation, we recently reported that performance on the 24-h iti task is impaired by a striatal-function blocking agent, the dopaminergic antagonist haloperidol, and not by a rhinal-function blocking agent, the muscarinic cholinergic antagonist scopolamine. |
2010-10-13 |
2023-08-12 |
monkey |
| Ricardo W Binfaré, Michela Mantovani, Josiane Budni, Adair Roberto S Santos, Ana Lúcia S Rodrigue. Involvement of dopamine receptors in the antidepressant-like effect of melatonin in the tail suspension test. European journal of pharmacology. vol 638. issue 1-3. 2010-09-27. PMID:20406627. |
was prevented by the pretreatment of mice with haloperidol (0.2mg/kg, i.p., a nonselective dopaminergic receptor antagonist), sch23390 (0.05 mg/kg, s.c., a selective dopamine d1 receptor antagonist), and sulpiride (50mg/kg, i.p., a selective dopamine d2 receptor antagonist). |
2010-09-27 |
2023-08-12 |
mouse |
| V S Shubina, V P Lavrovskaia, E N Bezgina, L L Pavlik, D A Moshko. [Cytochemical and ultrastructural characteristic of BHK-21 cells exposed to dopamine]. Morfologiia (Saint Petersburg, Russia). vol 137. issue 1. 2010-09-14. PMID:20593578. |
prior blockade of dopaminergic receptors by haloperidol did not change the following da effect both on the fluorescence intensity and cell ultrastructure. |
2010-09-14 |
2023-08-12 |
Not clear |
| Sarai Hess, Cristina Padoani, Laiana Carla Scorteganha, Iandra Holzmann, Angela Malheiros, Rosendo Augusto Yunes, Franco Delle Monache, Márcia Maria de Souz. Assessment of mechanisms involved in antinociception caused by myrsinoic acid B. Biological & pharmaceutical bulletin. vol 33. issue 2. 2010-09-03. PMID:20118542. |
in contrast, antinociception was not affected by naloxone (non-selective opioid receptor antagonist, 1.0 mg/kg), phaclofen (2.0 mg/kg) and bicuculline (1.0 mg/kg) gaba(b) and gaba(a) receptor antagonists, respectively, ondansetron (0.3 mg/kg) and ketaserin (1.0 mg/kg), (5-ht3 and 5-ht2 receptors, respectively) and haloperidol (0.2 mg/kg), a non-selective dopaminergic receptor. |
2010-09-03 |
2023-08-12 |
mouse |
| Taleen Der-Ghazarian, Sergios Charntikov, Fausto A Varela, Cynthia A Crawford, Sanders A McDougal. Effects of repeated and acute aripiprazole or haloperidol treatment on dopamine synthesis in the dorsal striatum of young rats: comparison to adult rats. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 5. 2010-07-29. PMID:20372943. |
the major findings of this study were that: (a) acute treatment with haloperidol and aripiprazole increased da synthesis while quinpirole reduced it; (b) pretreatment with haloperidol and aripiprazole blunted the synthesis-modulating effects of acutely administered dopaminergic drugs; and (c) da synthesis of young and adult rats was affected in a qualitatively similar manner by da agonist, antagonist, and partial agonist drugs. |
2010-07-29 |
2023-08-12 |
rat |
| José Luis Góngora-Alfar. [Caffeine as a preventive drug for Parkinson's disease: epidemiologic evidence and experimental support]. Revista de neurologia. vol 50. issue 4. 2010-05-18. PMID:20198594. |
recently, it was shown that male rats treated with moderate doses of caffeine (5 mg/kg/day) during six months, followed by a withdrawal period of at least two weeks, developed a greater resistance to the catalepsy induced with the dopaminergic antagonist haloperidol, which was possibly mediated by an increase of dopaminergic transmission in the corpus striatum. |
2010-05-18 |
2023-08-12 |
human |
| Tino Dyhring, Elsebet Ø Nielsen, Clas Sonesson, Fredrik Pettersson, Jonas Karlsson, Peder Svensson, Palle Christophersen, Nicholas Water. The dopaminergic stabilizers pridopidine (ACR16) and (-)-OSU6162 display dopamine D(2) receptor antagonism and fast receptor dissociation properties. European journal of pharmacology. vol 628. issue 1-3. 2010-04-05. PMID:19919834. |
in contrast to the high-affinity typical antipsychotics haloperidol and raclopride, the dopaminergic stabilizers acr16 and (-)-osu6162 both displayed fast dopamine d(2) receptor dissociation properties, a feature that has previously been suggested as a contributing factor to antipsychotic atypicality and attributed mainly to low receptor affinity. |
2010-04-05 |
2023-08-12 |
Not clear |