| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Joseph, S B Kandasamy, W A Hunt, T K Dalton, S Steven. Radiation-induced increases in sensitivity of cataleptic behavior to haloperidol: possible involvement of prostaglandins. Pharmacology, biochemistry, and behavior. vol 29. issue 2. 1988-06-09. PMID:3362928. |
in order to assess a possible action of prostaglandins and radiation on dopaminergic activity, the functioning of striatal dopaminergic autoreceptors was examined by determining the effects of varying concentrations of haloperidol on the k+-evoked release of dopamine from striatal slices obtained from parallel groups of animals treated as above. |
1988-06-09 |
2023-08-11 |
Not clear |
| S R McGurk, E D Levin, L L Butche. Cholinergic-dopaminergic interactions in radial-arm maze performance. Behavioral and neural biology. vol 49. issue 2. 1988-05-31. PMID:3365189. |
the muscarinic receptor blocker scopolamine and the dopaminergic antagonist haloperidol have been found to impair choice accuracy of rats in the radial-arm maze. |
1988-05-31 |
2023-08-11 |
rat |
| M Savasta, A Dubois, J Benavidès, B Scatto. Different plasticity changes in D1 and D2 receptors in rat striatal subregions following impairment of dopaminergic transmission. Neuroscience letters. vol 85. issue 1. 1988-05-27. PMID:2834672. |
the precise topographical changes in striatal d1 and d2 dopamine receptor density that occurred after chronic treatment with haloperidol or sch 23390 or after 6-hydroxydopamine-induced lesion of the mesostriatal dopaminergic pathway have been studied autoradiographically in the rat. |
1988-05-27 |
2023-08-11 |
rat |
| M Savasta, A Dubois, J Benavidès, B Scatto. Different plasticity changes in D1 and D2 receptors in rat striatal subregions following impairment of dopaminergic transmission. Neuroscience letters. vol 85. issue 1. 1988-05-27. PMID:2834672. |
subacute administration of haloperidol (2 mg/kg i.p., 18 days) or lesion of dopaminergic afferents provoked an increase in [3h]spiperone binding which was restricted to the ventro- and dorsolateral striatal sectors. |
1988-05-27 |
2023-08-11 |
rat |
| J P Grierson, M D James, J R Pearson, C A Wilso. The effect of selective D1 and D2 dopaminergic agents on sexual receptivity in the female rat. Neuropharmacology. vol 27. issue 2. 1988-05-06. PMID:2965316. |
the results of administration of mixed dopaminergic agents (dopa, 10-50 mg/kg with benserazide or 100-200 mg/kg alone and haloperidol 0.01-1.0 mg/kg) and selective d2 dopaminergic agents (ly 171555 2.5-800 micrograms/kg, bht 920 0.01-1.0 mg/kg and sulpiride 5-80 mg/kg) indicate that a central dopaminergic system has an inhibitory control on female sexual activity exerted through d2 receptors. |
1988-05-06 |
2023-08-11 |
rat |
| M A Sherman, R J Deans, M B Bolge. Haloperidol binding to monoclonal antibodies. Hypervariable region amino acid sequence determination. The Journal of biological chemistry. vol 263. issue 9. 1988-04-21. PMID:3267217. |
the primary sequences of five monoclonal antibodies (mabs a-e) which bind with various affinities (kd = 4-810 nm) to the d-2 dopaminergic antagonist, haloperidol, have been determined. |
1988-04-21 |
2023-08-11 |
Not clear |
| M A Sherman, M B Bolge. Haloperidol binding to monoclonal antibodies. Predictions of three-dimensional combining site structure via computer modeling. The Journal of biological chemistry. vol 263. issue 9. 1988-04-21. PMID:3346235. |
the amino acid sequences of five monoclonal antibodies (designated mabs a-e) which bind to the dopaminergic d-2 antagonist, haloperidol, with a variety of affinities (kd = 4-810 nm), have been used to build theoretical, three-dimensional, computer models of the variable region combining sites. |
1988-04-21 |
2023-08-11 |
Not clear |
| H A Tilson, G J Harry, K Nanry, P M Hudson, J S Hon. Ganglioside interactions with the dopaminergic system of rats. Journal of neuroscience research. vol 19. issue 1. 1988-03-25. PMID:3125345. |
the effects of ganglioside treatment on changes in dopaminergic function following 6-hydroxydopamine (6-ohda) or repeated exposure to haloperidol were studied in male fischer-344 rats. |
1988-03-25 |
2023-08-11 |
rat |
| B Costall, A M Domeney, R J Naylor, M B Tyer. Effects of the 5-HT3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain. British journal of pharmacology. vol 92. issue 4. 1988-03-22. PMID:2962686. |
it is concluded that the 5-ht3 receptor antagonist gr38032f, and the neuroleptic agents fluphenazine, sulpiride and haloperidol, can reduce raised mesolimbic dopaminergic activity in the rat and marmoset. |
1988-03-22 |
2023-08-11 |
rat |
| R Kuczenski, D S Segal, N J Leith, C D Applegat. Effects of amphetamine, methylphenidate, and apomorphine on regional brain serotonin and 5-hydroxyindole acetic acid. Psychopharmacology. vol 93. issue 3. 1988-03-03. PMID:2448842. |
pretreatment of animals with alpha-methyltyrosine at a dose sufficient to prevent the locomotor stimulation and stereotypy promoted by amphetamine, or by haloperidol, failed to prevent the amphetamine-induced increase in 5hiaa, indicating that these serotonergic effects are not secondary to the amphetamine facilitation of dopaminergic transmission. |
1988-03-03 |
2023-08-11 |
Not clear |
| P M Beardsley, R L Balste. Evaluation of antagonists of the discriminative stimulus and response rate effects of phencyclidine. The Journal of pharmacology and experimental therapeutics. vol 244. issue 1. 1988-02-24. PMID:3336008. |
drugs combined with pcp to test for antagonism included an alpha-1 (prazosin) and an alpha-2 (yohimbine) adrenergic antagonist, the adenosine receptor agonist, i-phenylisopropyl adenosine, the gamma-aminobutyric acid agonist, imidazole acetic acid, the dopaminergic antagonist, haloperidol, the acylating agent of the pcp receptor, metaphit, and the dopaminergic drugs (+)- and (-)-3-(3-hydroxyphenyl)-n-(1-propyl)piperidine. |
1988-02-24 |
2023-08-11 |
rat |
| J A Joseph, R E Berger, B T Engel, G S Rot. Age-related changes in the nigrostriatum: a behavioral and biochemical analysis. Journal of gerontology. vol 33. issue 5. 1988-02-04. PMID:299552. |
direct dopaminergic stimulation under apomorphine or dopaminergic receptor blockade with haloperidol produced no such age related deficits. |
1988-02-04 |
2023-08-11 |
rat |
| F Chaouloff, B Jeanrenau. 5-HT1A and alpha-2 adrenergic receptors mediate the hyperglycemic and hypoinsulinemic effects of 8-hydroxy-2-(di-n-propylamino)tetralin in the conscious rat. The Journal of pharmacology and experimental therapeutics. vol 243. issue 3. 1988-02-02. PMID:2826757. |
pretreatments with the dopaminergic blocker haloperidol, the alpha-1 adrenoceptor antagonist prazosin or the 5-ht2 blocker ketanserin were ineffective. |
1988-02-02 |
2023-08-11 |
rat |
| O B Kuz'min, P V Mikhaĭlenk. [Role of kidney prostaglandins, kinins and dopamine receptors in the natriuretic effect of ethacrynic acid]. Farmakologiia i toksikologiia. vol 50. issue 5. 1988-01-25. PMID:2446916. |
a blocker of dopaminergic receptors haloperidol (3 mg/kg subcutaneously) caused no changes in the rat kidney response to ethacrynic acid. |
1988-01-25 |
2023-08-11 |
rat |
| T P Jerussi, J F Capacchione, M J Benveng. Reversal of opioid-induced muscular rigidity in rats: evidence for alpha-2 adrenergic involvement. Pharmacology, biochemistry, and behavior. vol 28. issue 2. 1988-01-13. PMID:2891145. |
however, dopaminergic antagonists with adrenolytic activity (i.e., chlorpromazine, haloperidol) reversed rigidity, whereas sulpiride did not. |
1988-01-13 |
2023-08-11 |
rat |
| A Smiałowski, M Bija. Excitatory and inhibitory action of dopamine on hippocampal neurons in vitro. Involvement of D2 and D1 receptors. Neuroscience. vol 23. issue 1. 1988-01-11. PMID:2960914. |
having used selective dopaminergic agonists (pergolide and 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1h-3-benzazepines) and selective antagonists (haloperidol, spiperone, sulpiride and (r)-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3- benzazepine-7-ol), it was concluded that the excitation evoked by dopamine was due to activation of d2 dopamine receptors, while the inhibition was the result of d1 receptor activation. |
1988-01-11 |
2023-08-11 |
rat |
| C Delbende, S Jégou, D Tranchand-Bunel, G Pelletier, H Vaudr. Hypothalamic alpha-melanocyte-stimulating hormone (alpha-MSH) is not under dopaminergic control. Brain research. vol 423. issue 1-2. 1987-12-22. PMID:2960424. |
acute or 3-weeks chronic in vivo treatments with the dopaminergic agonists apomorphine (1 mg/kg: s.c.) and 2-br-alpha-ergocriptine (2.5 mg/kg; s.c.) or the dopaminergic antagonist haloperidol (0.15-3 mg/kg; i.p.) |
1987-12-22 |
2023-08-11 |
rat |
| T Sato, T Yoneyama, H K Kim, T A Suzuk. Effect of dopamine and haloperidol on the c-wave and light peak of light-induced retinal responses in chick eye. Documenta ophthalmologica. Advances in ophthalmology. vol 65. issue 1. 1987-12-15. PMID:2822368. |
the relation between dopaminergic cells (and centrifugal fibers), the electroretinogram (erg) c-wave, and the light peak were electrophysiologically investigated by observing the effects of a retrobulbar conduction block and intravitreal injection of either dopamine or haloperidol on these retinal responses. |
1987-12-15 |
2023-08-11 |
chicken |
| G F Steinfels, S W Tam, L Coo. Discriminative stimulus properties of a sigma receptor agonist in the rat: role of monoamine systems. European journal of pharmacology. vol 141. issue 1. 1987-12-14. PMID:2822445. |
activation of the dopaminergic system by apomorphine did not produce (+)-nanm ds however, haloperidol, which binds to the sigma receptor with high affinity, antagonized (+)-nanm ds. |
1987-12-14 |
2023-08-11 |
rat |
| A Iu Klintsova, N A Uranova, H Schenk, U Hasselhors. [Action of haloperidol on the ultrastructure of areas of the dopaminergic system of the brain]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 87. issue 7. 1987-12-08. PMID:3673382. |
[action of haloperidol on the ultrastructure of areas of the dopaminergic system of the brain]. |
1987-12-08 |
2023-08-11 |
Not clear |