| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John P Valenta, Martin O Job, Regina A Mangieri, Christina J Schier, Elaina C Howard, Rueben A Gonzale. μ-opioid receptors in the stimulation of mesolimbic dopamine activity by ethanol and morphine in Long-Evans rats: a delayed effect of ethanol. Psychopharmacology. vol 228. issue 3. 2014-02-17. PMID:23503684. |
it has been proposed that the μ-opioid receptor plays a role in ethanol reinforcement through modulation of ethanol-stimulated mesolimbic dopamine release. |
2014-02-17 |
2023-08-12 |
rat |
| Lucía Martí-Prats, María José Sánchez-Catalán, Alejandro Orrico, Teodoro Zornoza, Ana Polache, Luis Graner. Opposite motor responses elicited by ethanol in the posterior VTA: the role of acetaldehyde and the non-metabolized fraction of ethanol. Neuropharmacology. vol 72. 2014-02-11. PMID:23643753. |
recent electrophysiological evidence suggests that ethanol simultaneously exerts opposite effects on the activity of dopamine (da) neurons in the ventral tegmental area (vta) through two parallel mechanisms, one promoting and the other reducing the gaba release onto vta da neurons. |
2014-02-11 |
2023-08-12 |
rat |
| Caroline E Bass, Valentina P Grinevich, Dominic Gioia, Jonathan D Day-Brown, Keith D Bonin, Garret D Stuber, Jeff L Weiner, Evgeny A Budygi. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Frontiers in behavioral neuroscience. vol 7. 2013-12-10. PMID:24324415. |
optogenetic stimulation of vta dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. |
2013-12-10 |
2023-08-12 |
rat |
| Caroline E Bass, Valentina P Grinevich, Dominic Gioia, Jonathan D Day-Brown, Keith D Bonin, Garret D Stuber, Jeff L Weiner, Evgeny A Budygi. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Frontiers in behavioral neuroscience. vol 7. 2013-12-10. PMID:24324415. |
there is compelling evidence that acute ethanol exposure stimulates ventral tegmental area (vta) dopamine cell activity and that vta-dependent dopamine release in terminal fields within the nucleus accumbens plays an integral role in the regulation of ethanol drinking behaviors. |
2013-12-10 |
2023-08-12 |
rat |
| Caroline E Bass, Valentina P Grinevich, Dominic Gioia, Jonathan D Day-Brown, Keith D Bonin, Garret D Stuber, Jeff L Weiner, Evgeny A Budygi. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Frontiers in behavioral neuroscience. vol 7. 2013-12-10. PMID:24324415. |
unfortunately, due to technical limitations, the specific temporal dynamics linking vta dopamine cell activation and ethanol self-administration are not known. |
2013-12-10 |
2023-08-12 |
rat |
| Caroline E Bass, Valentina P Grinevich, Dominic Gioia, Jonathan D Day-Brown, Keith D Bonin, Garret D Stuber, Jeff L Weiner, Evgeny A Budygi. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Frontiers in behavioral neuroscience. vol 7. 2013-12-10. PMID:24324415. |
in fact, establishing a causal link between specific patterns of dopamine transmission and ethanol drinking behaviors has proven elusive. |
2013-12-10 |
2023-08-12 |
rat |
| Caroline E Bass, Valentina P Grinevich, Dominic Gioia, Jonathan D Day-Brown, Keith D Bonin, Garret D Stuber, Jeff L Weiner, Evgeny A Budygi. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Frontiers in behavioral neuroscience. vol 7. 2013-12-10. PMID:24324415. |
we then used this approach to precisely control vta dopamine transmission during voluntary ethanol drinking sessions. |
2013-12-10 |
2023-08-12 |
rat |
| Caroline E Bass, Valentina P Grinevich, Dominic Gioia, Jonathan D Day-Brown, Keith D Bonin, Garret D Stuber, Jeff L Weiner, Evgeny A Budygi. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Frontiers in behavioral neuroscience. vol 7. 2013-12-10. PMID:24324415. |
notably, using this optogenetic approach in rats engaged in an intermittent ethanol drinking procedure, we found that tonic, but not phasic, stimulation of vta dopamine cells selectively attenuated ethanol drinking behaviors. |
2013-12-10 |
2023-08-12 |
rat |
| Caroline E Bass, Valentina P Grinevich, Dominic Gioia, Jonathan D Day-Brown, Keith D Bonin, Garret D Stuber, Jeff L Weiner, Evgeny A Budygi. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Frontiers in behavioral neuroscience. vol 7. 2013-12-10. PMID:24324415. |
collectively, these data demonstrate the effectiveness of a novel viral targeting strategy that can be used to restrict opsin expression to dopamine cells in standard outbred animals and provide the first causal evidence demonstrating that tonic activation of vta dopamine neurons selectively decreases ethanol self-administration behaviors. |
2013-12-10 |
2023-08-12 |
rat |
| Yuya Ise, Tomohisa Mori, Shirou Katayama, Hiroshi Nagase, Tsutomu Suzuk. Rewarding effects of ethanol combined with low doses of morphine through dopamine D1 receptors. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 80. issue 1. 2013-12-09. PMID:23470804. |
rewarding effects of ethanol combined with low doses of morphine through dopamine d1 receptors. |
2013-12-09 |
2023-08-12 |
rat |
| Yuya Ise, Tomohisa Mori, Shirou Katayama, Hiroshi Nagase, Tsutomu Suzuk. Rewarding effects of ethanol combined with low doses of morphine through dopamine D1 receptors. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 80. issue 1. 2013-12-09. PMID:23470804. |
the combined effect of ethanol and morphine was significantly attenuated by naloxone (0.3 mg/kg, s.c.), naltrindole (1.0 mg/kg, s.c.), or long-term administration of the dopamine d1 receptor antagonist sch23390 (1.0 mg/kg/day, s.c.). |
2013-12-09 |
2023-08-12 |
rat |
| Yuya Ise, Tomohisa Mori, Shirou Katayama, Hiroshi Nagase, Tsutomu Suzuk. Rewarding effects of ethanol combined with low doses of morphine through dopamine D1 receptors. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 80. issue 1. 2013-12-09. PMID:23470804. |
these results suggest that the rewarding effect induced by ethanol and a low dose of morphine is mediated by activation of the central opioidergic and dopaminergic systems through dopamine d1 receptors. |
2013-12-09 |
2023-08-12 |
rat |
| Brian A McMillen, Courtney L Lommatzsch, Michael J Sayonh, Helen L William. Interactions of a Dopamine D1 Receptor Agonist with Glutamate NMDA Receptor Antagonists on the Volitional Consumption of Ethanol by the mHEP Rat. Pharmaceuticals (Basel, Switzerland). vol 6. issue 4. 2013-11-26. PMID:24276118. |
interactions of a dopamine d1 receptor agonist with glutamate nmda receptor antagonists on the volitional consumption of ethanol by the mhep rat. |
2013-11-26 |
2023-08-12 |
rat |
| Kazuhiro Kurokawa, Koji Mizuno, Seitaro Ohkum. Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence. Alcoholism, clinical and experimental research. vol 37. issue 5. 2013-11-12. PMID:23278119. |
dopamine d1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence. |
2013-11-12 |
2023-08-12 |
mouse |
| Gerald A Deehan, Eric A Engleman, Zheng-Ming Ding, William J McBride, Zachary A Rod. Microinjections of acetaldehyde or salsolinol into the posterior ventral tegmental area increase dopamine release in the nucleus accumbens shell. Alcoholism, clinical and experimental research. vol 37. issue 5. 2013-11-12. PMID:23278868. |
published findings indicate that acetaldehyde (acd; the first metabolite of ethanol [etoh]) and salsolinol (sal; formed through the nonenzymatic condensation of acd and dopamine [da]) can be formed following etoh consumption. |
2013-11-12 |
2023-08-12 |
Not clear |
| Christina J Schier, Geoffrey A Dilly, Rueben A Gonzale. Intravenous ethanol increases extracellular dopamine in the medial prefrontal cortex of the Long-Evans rat. Alcoholism, clinical and experimental research. vol 37. issue 5. 2013-11-12. PMID:23421849. |
intravenous ethanol increases extracellular dopamine in the medial prefrontal cortex of the long-evans rat. |
2013-11-12 |
2023-08-12 |
rat |
| Jian Mao, Hong Ma, Yan Xu, Yang Su, Huiyang Zhu, Rui Wang, Fankai Lin, Hong Qing, Yulin Den. Increased levels of monoamine-derived potential neurotoxins in fetal rat brain exposed to ethanol. Neurochemical research. vol 38. issue 2. 2013-10-17. PMID:23184185. |
determined by hplc with electrochemical detector, the levels of dopamine and 5-hydroxytryptamine in whole fetal brain were not remarkably altered by ethanol treatment, while the levels of homovanillic acid and 5-hydroxyindole acetic acid in high dose (4.0 g/kg) of ethanol-treated rats were significantly decreased compared to that in the control animals. |
2013-10-17 |
2023-08-12 |
rat |
| Taehyun Kim, David J Hinton, Sandy Johng, Jia Bei Wang, Doo-Sup Cho. Levo-tetrahydropalmatine decreases ethanol drinking and antagonizes dopamine D2 receptor-mediated signaling in the mouse dorsal striatum. Behavioural brain research. vol 244. 2013-09-30. PMID:23376703. |
levo-tetrahydropalmatine decreases ethanol drinking and antagonizes dopamine d2 receptor-mediated signaling in the mouse dorsal striatum. |
2013-09-30 |
2023-08-12 |
mouse |
| Sudarat Nimitvilai, Devinder S Arora, Maureen A McElvain, Mark S Brodi. Ethanol blocks the reversal of prolonged dopamine inhibition of dopaminergic neurons of the ventral tegmental area. Alcoholism, clinical and experimental research. vol 36. issue 11. 2013-08-20. PMID:22551160. |
ethanol blocks the reversal of prolonged dopamine inhibition of dopaminergic neurons of the ventral tegmental area. |
2013-08-20 |
2023-08-12 |
Not clear |
| Laura Font, Miguel Á Luján, Raúl Pasto. Involvement of the endogenous opioid system in the psychopharmacological actions of ethanol: the role of acetaldehyde. Frontiers in behavioral neuroscience. vol 7. 2013-08-05. PMID:23914161. |
ethanol increases the release of β-endorphin from the hypothalamic arcuate nucleus (narc), which can modulate activity of other neurotransmitter systems such as mesolimbic dopamine (da). |
2013-08-05 |
2023-08-12 |
Not clear |