| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jordan T Yorgason, Mark J Ferris, Scott C Steffensen, Sara R Jone. Frequency-dependent effects of ethanol on dopamine release in the nucleus accumbens. Alcoholism, clinical and experimental research. vol 38. issue 2. 2014-09-29. PMID:24117706. |
ethanol (etoh) is known to have excitatory effects on dopamine (da) release, with moderate-to-high doses (0.5 to 2.5 g/kg) of acute etoh enhancing da neuron firing rates in the ventral tegmental area (vta) and da levels in the nucleus accumbens (nac). |
2014-09-29 |
2023-08-12 |
Not clear |
| Jamie H Rose, Erin S Calipari, Tiffany A Mathews, Sara R Jone. Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics. PloS one. vol 8. issue 12. 2014-09-29. PMID:24349553. |
dopamine elevations in the nucleus accumbens and caudate-putamen regulate locomotor behavior for most drugs, including ethanol; thus, we aimed to determine if differences in these regions predict strain differences in ethanol-induced locomotor activity. |
2014-09-29 |
2023-08-12 |
mouse |
| Jamie H Rose, Erin S Calipari, Tiffany A Mathews, Sara R Jone. Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics. PloS one. vol 8. issue 12. 2014-09-29. PMID:24349553. |
previous studies suggest that ethanol interacts with the dopamine transporter, potentially mediating its locomotor activating effects; however, we found that ethanol had no effects on dopamine uptake in either strain. |
2014-09-29 |
2023-08-12 |
mouse |
| Jamie H Rose, Erin S Calipari, Tiffany A Mathews, Sara R Jone. Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics. PloS one. vol 8. issue 12. 2014-09-29. PMID:24349553. |
ex vivo voltammetry allows for the determination of ethanol effects on presynaptic dopamine terminals, independent of drug-induced changes in firing rates of afferent inputs from either dopamine neurons or other neurotransmitter systems. |
2014-09-29 |
2023-08-12 |
mouse |
| Jamie H Rose, Erin S Calipari, Tiffany A Mathews, Sara R Jone. Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics. PloS one. vol 8. issue 12. 2014-09-29. PMID:24349553. |
however, differences in striatal dopamine dynamics did not predict the locomotor-activating effects of ethanol, since the inhibitory effects of ethanol on dopamine release were similar between strains. |
2014-09-29 |
2023-08-12 |
mouse |
| Jamie H Rose, Erin S Calipari, Tiffany A Mathews, Sara R Jone. Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics. PloS one. vol 8. issue 12. 2014-09-29. PMID:24349553. |
because of the role of the dopamine system in reinforcement and reward learning, differences in dopamine signaling between the strains could have implications for addiction-related behaviors that extend beyond ethanol effects in the striatum. |
2014-09-29 |
2023-08-12 |
mouse |
| Koji Mizuno, Kazuhiro Kurokawa, Seitaro Ohkum. [Mechanisms of ethanol-induced type I IP3 receptor expression]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 33. issue 4. 2014-09-25. PMID:25069252. |
in this report, we demonstrate the functional relationship between ethanol-induced rewarding effect and ip3r-1 expression and regulatory mechanisms of ip3r-1 expression after chronic ethanol exposure, especially focusing on ca(2+)-related signal transduction pathways via dopamine d1 receptors using mouse cerebral cortical neurons. |
2014-09-25 |
2023-08-13 |
mouse |
| Amanda J Quisenberry, Thomas Prisinzano, Lisa E Bake. Combined effects of modafinil and d-amphetamine in male Sprague-Dawley rats trained to discriminate d-amphetamine. Pharmacology, biochemistry, and behavior. vol 110. 2014-07-15. PMID:23880213. |
the selective d2 dopamine agonist, pnu-91356a, was also tested as a positive control and ethanol and morphine were tested as negative controls. |
2014-07-15 |
2023-08-12 |
rat |
| Nathan D Schilaty, David M Hedges, Eun Young Jang, Ryan J Folsom, Jordan T Yorgason, J Michael McIntosh, Scott C Steffense. Acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors. The Journal of pharmacology and experimental therapeutics. vol 349. issue 3. 2014-07-06. PMID:24643637. |
acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors. |
2014-07-06 |
2023-08-12 |
mouse |
| Nathan D Schilaty, David M Hedges, Eun Young Jang, Ryan J Folsom, Jordan T Yorgason, J Michael McIntosh, Scott C Steffense. Acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors. The Journal of pharmacology and experimental therapeutics. vol 349. issue 3. 2014-07-06. PMID:24643637. |
electrophysiology and microdialysis studies have provided compelling evidence that moderate to high ethanol concentrations enhance dopamine (da) neurotransmission in the nucleus accumbens (nac) through the mesolimbic da system. |
2014-07-06 |
2023-08-12 |
mouse |
| Pia Jaatinen, Maija Sarviharju, Noora Raivio, C J Peter Eriksson, Antti Hervonen, Kalervo Kiianma. Effects of Lifelong Ethanol Consumption on Brain Monoamine Transmitters in Alcohol-Preferring Alko Alcohol (AA) Rats. Brain sciences. vol 3. issue 2. 2014-06-25. PMID:24961425. |
the data suggest that a continuous intake of moderate amounts of ethanol does not enhance the age-related alterations in brain monoamine neurotransmission, while the decline in the brain level of dopamine associated with aging may be a factor contributing to age-related neurological disorders. |
2014-06-25 |
2023-08-13 |
rat |
| S E Kawakami, I M H Quadros, R B Machado, D Sucheck. Sex-dependent effects of maternal separation on plasma corticosterone and brain monoamines in response to chronic ethanol administration. Neuroscience. vol 253. 2014-06-19. PMID:23994181. |
in lms females, chronic ethanol increased dopamine and serotonin concentrations in the frontal cortex, relative to acute ethanol lms and to chronic ethanol-treated afr groups (p<0.05). |
2014-06-19 |
2023-08-12 |
mouse |
| S E Kawakami, I M H Quadros, R B Machado, D Sucheck. Sex-dependent effects of maternal separation on plasma corticosterone and brain monoamines in response to chronic ethanol administration. Neuroscience. vol 253. 2014-06-19. PMID:23994181. |
in lms males, chronic ethanol increased hippocampal noradrenaline, dopamine, serotonin and metabolites when compared to respective afr controls, as well as acute lms. |
2014-06-19 |
2023-08-12 |
mouse |
| Mariko Murata, Kaoru Midorikawa, Shosuke Kawanish. Oxidative DNA damage and mammary cell proliferation by alcohol-derived salsolinol. Chemical research in toxicology. vol 26. issue 10. 2014-05-26. PMID:24020587. |
salsolinol (sal) is endogenously formed by a condensation reaction of dopamine with acetaldehyde, a major ethanol metabolite, and sal is detected in blood and urine after alcohol intake. |
2014-05-26 |
2023-08-12 |
Not clear |
| Henri A J Puttonen, Maria Sundvik, Stanislav Rozov, Yu-Chia Chen, Pertti Panul. Acute ethanol treatment upregulates Th1, Th2, and Hdc in larval zebrafish in stable networks. Frontiers in neural circuits. vol 7. 2014-05-19. PMID:23754986. |
at the highest ethanol concentration dopamine levels decreased significantly after a 10-min treatment. |
2014-05-19 |
2023-08-12 |
zebrafish |
| Henri A J Puttonen, Maria Sundvik, Stanislav Rozov, Yu-Chia Chen, Pertti Panul. Acute ethanol treatment upregulates Th1, Th2, and Hdc in larval zebrafish in stable networks. Frontiers in neural circuits. vol 7. 2014-05-19. PMID:23754986. |
we found that ethanol upregulates key genes involved in the biosynthesis of histamine (hdc) and dopamine (th1 and th2) following a short 10-min ethanol treatment, measured by qpcr. |
2014-05-19 |
2023-08-12 |
zebrafish |
| Henri A J Puttonen, Maria Sundvik, Stanislav Rozov, Yu-Chia Chen, Pertti Panul. Acute ethanol treatment upregulates Th1, Th2, and Hdc in larval zebrafish in stable networks. Frontiers in neural circuits. vol 7. 2014-05-19. PMID:23754986. |
the results suggest that acute ethanol rapidly decreases dopamine levels, and activates both forms or th to replenish the dopamine stores within 30 min. |
2014-05-19 |
2023-08-12 |
zebrafish |
| Henri A J Puttonen, Maria Sundvik, Stanislav Rozov, Yu-Chia Chen, Pertti Panul. Acute ethanol treatment upregulates Th1, Th2, and Hdc in larval zebrafish in stable networks. Frontiers in neural circuits. vol 7. 2014-05-19. PMID:23754986. |
as both dopamine and histamine are known to be involved in the behavioral effects of ethanol and locomotor stimulation, these results suggest that rapid adaptations of these networks are associated with altered locomotor activity. |
2014-05-19 |
2023-08-12 |
zebrafish |
| Reza Azanchi, Karla R Kaun, Ulrike Heberlei. Competing dopamine neurons drive oviposition choice for ethanol in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 52. 2014-02-27. PMID:24324162. |
competing dopamine neurons drive oviposition choice for ethanol in drosophila. |
2014-02-27 |
2023-08-12 |
drosophila_melanogaster |
| John P Valenta, Martin O Job, Regina A Mangieri, Christina J Schier, Elaina C Howard, Rueben A Gonzale. μ-opioid receptors in the stimulation of mesolimbic dopamine activity by ethanol and morphine in Long-Evans rats: a delayed effect of ethanol. Psychopharmacology. vol 228. issue 3. 2014-02-17. PMID:23503684. |
μ-opioid receptors in the stimulation of mesolimbic dopamine activity by ethanol and morphine in long-evans rats: a delayed effect of ethanol. |
2014-02-17 |
2023-08-12 |
rat |