| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amvrosios Orfanidis, Helen Gika, Orthodoxia Mastrogianni, Adamantios Krokos, Georgios Theodoridis, Eleni Zaggelidou, Nikolaos Raiko. Determination of drugs of abuse and pharmaceuticals in skeletal tissue by UHPLC-MS/MS. Forensic science international. vol 290. 2018-09-27. PMID:30036735. |
the target compounds comprise pharmaceuticals (antipsychotics and antidepressants) and some of the most important groups of drugs of abuse: opiates, cocaine, cannabinoids, amphetamines and benzodiazepines. |
2018-09-27 |
2023-08-13 |
human |
| Li-Wei Tung, Guan-Ling Lu, Yen-Hsien Lee, Lung Yu, Hsin-Jung Lee, Emma Leishman, Heather Bradshaw, Ling-Ling Hwang, Ming-Shiu Hung, Ken Mackie, Andreas Zimmer, Lih-Chu Chio. Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons. Nature communications. vol 7. 2018-08-27. PMID:27448020. |
this stress-induced reinstatement of cocaine cpp depends on type 1 orexin receptors (ox1rs), type 1 cannabinoid receptors (cb1rs) and diacylglycerol lipase (dagl) in the vta. |
2018-08-27 |
2023-08-13 |
mouse |
| László Institóris, Előd Hidvégi, Adrienn Dobos, Éva Sija, Éva M Kereszty, László Balázs Tajti, Gábor Pál Somogyi, Tibor Varg. The role of illicit, licit, and designer drugs in the traffic in Hungary. Forensic science international. vol 275. 2018-07-05. PMID:28412575. |
the distribution of drug types in each category were: [1] classical illicit drugs: cannabis (432), amphetamine (321), and cocaine (79); [2] medicines: alprazolam (94) and clonazepam (36); [3] sdds: pentedrone (137) and α-pvp (33); [4] synthetic cannabinoids: ab-chminaca (46) and mdmb-chmica (30). |
2018-07-05 |
2023-08-13 |
Not clear |
| Marcel Grapp, Christoph Kaufmann, Martin Ebbeck. Toxicological investigation of forensic cases related to the designer drug 3,4-methylenedioxypyrovalerone (MDPV): Detection, quantification and studies on human metabolism by GC-MS. Forensic science international. vol 273. 2018-05-30. PMID:28187296. |
for most of the analytically confirmed mdpv cases we could prove co-consumption of other psychotropic drugs with frequent occurrence of opiates and cannabinoids in 22% of the cases, followed by benzodiazepines and cocaine in 17%. |
2018-05-30 |
2023-08-13 |
human |
| Shaness A Grenald, Madison A Young, Yue Wang, Michael H Ossipov, Mohab M Ibrahim, Tally M Largent-Milnes, Todd W Vandera. Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists. Neuropharmacology. vol 116. 2018-05-09. PMID:28007501. |
in recent years, cannabinoid receptors have been identified as potential modulators of pain and rewarding behaviors associated with cocaine, nicotine and ethanol in preclinical models. |
2018-05-09 |
2023-08-13 |
Not clear |
| Alexandros G Asimakopoulos, Pranav Kannan, Sean Higgins, Kurunthachalam Kanna. Determination of 89 drugs and other micropollutants in unfiltered wastewater and freshwater by LC-MS/MS: an alternative sample preparation approach. Analytical and bioanalytical chemistry. vol 409. issue 26. 2018-04-30. PMID:28815276. |
the target chemicals fall under the classes of amphetamine-type stimulants, cocaine compounds, opiates and opioids, benzodiazepines, lysergic compounds, antipsychotics, anesthetics, antiepileptics, antidepressants, sympathomimetics, cannabinoids, blood thinners, antihistamines, β-blockers, caffeine derivatives, nicotine derivatives, z-drugs, new designer drugs, and alzheimer medications. |
2018-04-30 |
2023-08-13 |
Not clear |
| Tamaki Hayas. Epigenetic mechanisms associated with addiction-related behavioural effects of nicotine and/or cocaine: implication of the endocannabinoid system. Behavioural pharmacology. vol 28. issue 7. 2018-04-16. PMID:28704272. |
epigenetic mechanisms associated with addiction-related behavioural effects of nicotine and/or cocaine: implication of the endocannabinoid system. |
2018-04-16 |
2023-08-13 |
Not clear |
| Arani Nanavati, Leal C Herlit. Tubulointerstitial Injury and Drugs of Abuse. Advances in chronic kidney disease. vol 24. issue 2. 2018-03-27. PMID:28284383. |
agents addressed in this review are synthetic cannabinoids, "bath salts," ecstasy, anabolic steroids, inhaled solvents, heroin, and cocaine. |
2018-03-27 |
2023-08-13 |
Not clear |
| María A Aguilar, Juan Carlos Ledesma, Marta Rodríguez-Arias, Carles Penalva, Carmen Manzanedo, José Miñarro, M Carmen Arena. Adolescent Exposure to the Synthetic Cannabinoid WIN 55212-2 Modifies Cocaine Withdrawal Symptoms in Adult Mice. International journal of molecular sciences. vol 18. issue 6. 2018-03-23. PMID:28635664. |
adolescent exposure to the synthetic cannabinoid win 55212-2 modifies cocaine withdrawal symptoms in adult mice. |
2018-03-23 |
2023-08-13 |
mouse |
| María A Aguilar, Juan Carlos Ledesma, Marta Rodríguez-Arias, Carles Penalva, Carmen Manzanedo, José Miñarro, M Carmen Arena. Adolescent Exposure to the Synthetic Cannabinoid WIN 55212-2 Modifies Cocaine Withdrawal Symptoms in Adult Mice. International journal of molecular sciences. vol 18. issue 6. 2018-03-23. PMID:28635664. |
we pre-treated juvenile mice with the cannabinoid cb1 receptor agonist win 55212-2 (win) and then subjected them to a chronic cocaine treatment during adulthood. |
2018-03-23 |
2023-08-13 |
mouse |
| Dan P Covey, Natalie E Zlebnik, Joseph F Chee. Endocannabinoid Regulation of Cocaine Reinforcement: an Upper or Downer? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-02-22. PMID:27406912. |
endocannabinoid regulation of cocaine reinforcement: an upper or downer? |
2018-02-22 |
2023-08-13 |
Not clear |
| Juliana Nichterwitz Scherer, Taís Regina Fiorentin, Bruna Tassi Borille, Graciela Pasa, Tanara Rosangela Vieira Sousa, Lisia von Diemen, Renata Pereira Limberger, Flavio Pechansk. Reliability of point-of-collection testing devices for drugs of abuse in oral fluid: A systematic review and meta-analysis. Journal of pharmaceutical and biomedical analysis. vol 143. 2018-02-02. PMID:28577420. |
the reliability measures for detection of the five most important drug classes - cocaine, amphetamines, benzodiazepines, cannabinoids and opioids, are reported. |
2018-02-02 |
2023-08-13 |
human |
| M J Sanchez-Catalan, J Kaufling, F Georges, P Veinante, M Barro. The antero-posterior heterogeneity of the ventral tegmental area. Neuroscience. vol 282. 2018-01-26. PMID:25241061. |
this antero-posterior heterogeneity concerns locomotor activity, conditioned place preference and intracranial self-administration, and can be seen in response to ethanol, acetaldehyde, salsolinol, opioids including morphine, cholinergic agonists including nicotine, cocaine, cannabinoids and after local manipulation of gaba and serotonin receptors. |
2018-01-26 |
2023-08-13 |
Not clear |
| Elena Martín-García, Lucie Bourgoin, Adeline Cathala, Fernando Kasanetz, Miguel Mondesir, Ana Gutiérrez-Rodriguez, Leire Reguero, Jean-François Fiancette, Pedro Grandes, Umberto Spampinato, Rafael Maldonado, Pier Vincenzo Piazza, Giovanni Marsicano, Véronique Deroche-Gamone. Differential Control of Cocaine Self-Administration by GABAergic and Glutamatergic CB1 Cannabinoid Receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:26612422. |
differential control of cocaine self-administration by gabaergic and glutamatergic cb1 cannabinoid receptors. |
2018-01-09 |
2023-08-13 |
mouse |
| Pietro Papa, Loretta Rocchi, Laura Maria Rolandi, Marcello Di Tuccio, Marco Biffi, Antonella Vall. Illicit drugs in Emergency Department patients injured in road traffic accidents. Annali dell'Istituto superiore di sanita. vol 53. issue 1. 2018-01-04. PMID:28361803. |
10.6% (95% ci 9.2 to 12.1) of the 1730 drivers were under the influence of drug, being blood concentration above the cut-off limit for at least one active substance; the proportion of illicit drugs in blood was cocaine 5.7 % (95% ci 4.7 to 6.9), cannabinoids 3.7 % (95% ci 2.9 to 4.7), opiates 1.4% (95% ci 0.9 to 2.1), methadone 1.4% (95% ci 0.9 to 2.1), amphetamines 0.2% (95% ci 0.04 to 0.5). |
2018-01-04 |
2023-08-13 |
human |
| Pietro Papa, Loretta Rocchi, Laura Maria Rolandi, Marcello Di Tuccio, Marco Biffi, Antonella Vall. Illicit drugs in Emergency Department patients injured in road traffic accidents. Annali dell'Istituto superiore di sanita. vol 53. issue 1. 2018-01-04. PMID:28361803. |
trend in proportion showed similar percentage (about 5%) of cocaine and cannabinoids consumption in the last two years. |
2018-01-04 |
2023-08-13 |
human |
| Catia Balducci, David C Green, Paola Romagnoli, Mattia Perilli, Christer Johansson, Pavlos Panteliadis, Angelo Cecinat. Cocaine and cannabinoids in the atmosphere of Northern Europe cities, comparison with Southern Europe and wastewater analysis. Environment international. vol 97. 2017-11-30. PMID:27665117. |
cocaine and cannabinoids in the atmosphere of northern europe cities, comparison with southern europe and wastewater analysis. |
2017-11-30 |
2023-08-13 |
Not clear |
| Catia Balducci, David C Green, Paola Romagnoli, Mattia Perilli, Christer Johansson, Pavlos Panteliadis, Angelo Cecinat. Cocaine and cannabinoids in the atmosphere of Northern Europe cities, comparison with Southern Europe and wastewater analysis. Environment international. vol 97. 2017-11-30. PMID:27665117. |
this study reports the first investigation of atmospheric illicit drug concentrations in northern europe using measurements of cocaine and cannabinoids in amsterdam, london and stockholm. |
2017-11-30 |
2023-08-13 |
Not clear |
| Eduardo A V Marinho, Alexandre J Oliveira-Lima, Thais S Yokoyama, Renan Santos-Baldaia, Luciana T C Ribeiro, Marilia A Baldaia, Raphael Wuo da Silva, Andre Willian Hollais, Fernanda Talhati, Beatriz Monteiro Longo, Lais Fernanda Berro, Roberto Frussa-Filh. Post-sensitization treatment with rimonabant blocks the expression of cocaine-induced behavioral sensitization and c-Fos protein in mice. Pharmacology, biochemistry, and behavior. vol 156. 2017-11-09. PMID:28366798. |
our findings add to the evidence that drugs targeting cb1 receptors are good candidates for the treatment of cocaine abuse and provide further insights into the mechanisms underlying endocannabinoid signaling within the brain reward system in the context of cocaine abuse. |
2017-11-09 |
2023-08-13 |
mouse |
| Meena K Yadav, Michael D Short, Rupak Aryal, Cobus Gerber, Ben van den Akker, Christopher P Sain. Occurrence of illicit drugs in water and wastewater and their removal during wastewater treatment. Water research. vol 124. 2017-10-20. PMID:28843086. |
this review critically evaluates the types and concentrations of key illicit drugs (cocaine, amphetamines, cannabinoids, opioids and their metabolites) found in wastewater, surface water and drinking water sources worldwide and what is known on the effectiveness of wastewater treatment in removing such compounds. |
2017-10-20 |
2023-08-13 |
Not clear |