| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eduardo Blanco, Pablo Galeano, Ana Palomino, Francisco J Pavón, Patricia Rivera, Antonia Serrano, Francisco Alen, Leticia Rubio, Antonio Vargas, Estela Castilla-Ortega, Juan Decara, Ainhoa Bilbao, Fernando Rodríguez de Fonseca, Juan Suáre. Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 3. 2016-12-13. PMID:26811312. |
overall, these findings suggest that repeated cocaine administration resulting in locomotor sensitization induces a down-regulation of the endocannabinoid signaling that could contribute to the specifically increased glun1 expression observed in the hippocampus of cocaine-sensitized mice. |
2016-12-13 |
2023-08-13 |
mouse |
| Wilco F Duvivier, Ruth J P Peeters, Teris A van Beek, Michel W F Niele. Evidence based decontamination protocols for the removal of external Δ9-tetrahydrocannabinol (THC) from contaminated hair. Forensic science international. vol 259. 2016-11-09. PMID:26773221. |
current literature about decontamination strategies is mainly focused on external cocaine contamination and no consensus on the best decontamination procedure for hair samples containing cannabinoids has been reached so far. |
2016-11-09 |
2023-08-13 |
Not clear |
| M Rodríguez-Arias, C Roger-Sánchez, I Vilanova, N Revert, C Manzanedo, J Miñarro, M A Aguila. Effects of Cannabinoid Exposure during Adolescence on the Conditioned Rewarding Effects of WIN 55212-2 and Cocaine in Mice: Influence of the Novelty-Seeking Trait. Neural plasticity. vol 2016. 2016-11-09. PMID:26881125. |
effects of cannabinoid exposure during adolescence on the conditioned rewarding effects of win 55212-2 and cocaine in mice: influence of the novelty-seeking trait. |
2016-11-09 |
2023-08-13 |
mouse |
| M Rodríguez-Arias, C Roger-Sánchez, I Vilanova, N Revert, C Manzanedo, J Miñarro, M A Aguila. Effects of Cannabinoid Exposure during Adolescence on the Conditioned Rewarding Effects of WIN 55212-2 and Cocaine in Mice: Influence of the Novelty-Seeking Trait. Neural plasticity. vol 2016. 2016-11-09. PMID:26881125. |
adolescent exposure to cannabinoids enhances the behavioural effects of cocaine, and high novelty-seeking trait predicts greater sensitivity to the conditioned place preference (cpp) induced by this drug. |
2016-11-09 |
2023-08-13 |
mouse |
| M Rodríguez-Arias, C Roger-Sánchez, I Vilanova, N Revert, C Manzanedo, J Miñarro, M A Aguila. Effects of Cannabinoid Exposure during Adolescence on the Conditioned Rewarding Effects of WIN 55212-2 and Cocaine in Mice: Influence of the Novelty-Seeking Trait. Neural plasticity. vol 2016. 2016-11-09. PMID:26881125. |
adolescent exposure to this cannabinoid agonist increased the rewarding effects of 1 mg/kg of cocaine in both hns and lns mice, and in hns mice it also increased the reinstating effect of a low dose of cocaine. |
2016-11-09 |
2023-08-13 |
mouse |
| Piotr Adamowicz, Joanna Gieroń, Dominika Gil, Wojciech Lechowicz, Agnieszka Skulska, Bogdan Tokarczy. The prevalence of new psychoactive substances in biological material - a three-year review of casework in Poland. Drug testing and analysis. vol 8. issue 1. 2016-10-18. PMID:26666629. |
nps (one or more) with other conventional drugs (like amphetamines, cannabinoids, cocaine, and benzodiazepines) were detected in most (65%) of the cases. |
2016-10-18 |
2023-08-13 |
Not clear |
| Dilek Battal, Allan J Barnes, Marisol S Castaneto, Thomas M Martin, Kevin L Klette, Marilyn A Huesti. Urine Mescaline Screening With a Biochip Array Immunoassay and Quantification by Gas Chromatography-Mass Spectrometry. Therapeutic drug monitoring. vol 37. issue 6. 2016-09-06. PMID:25992796. |
twenty thousand seventeen urine specimens negative for cannabinoids, cocaine, opiates, and amphetamines were tested for mescaline with the randox drugs of abuse v (doa-v) biochip array immunoassay at the manufacturer's recommended cutoff of 6 mcg/l. |
2016-09-06 |
2023-08-13 |
Not clear |
| Chrislean Jun Botanas, June Bryan de la Peña, Irene Joy Dela Pena, Reinholdgher Tampus, Hee Jin Kim, Seong Shoon Yoon, Joung-Wook Seo, Eun Ju Jeong, Jae Hoon Cheon. Evaluation of the abuse potential of AM281, a new synthetic cannabinoid CB1 receptor antagonist. European journal of pharmacology. vol 766. 2016-08-18. PMID:26450088. |
however, recent reports have suggested that cannabinoid cb1 receptor antagonists may share similar behavioral effects with other drugs of abuse such as cocaine and amphetamine. |
2016-08-18 |
2023-08-13 |
rat |
| Rubén García-Cabrerizo, M Julia García-Fuste. Opposite regulation of cannabinoid CB1 and CB2 receptors in the prefrontal cortex of rats treated with cocaine during adolescence. Neuroscience letters. vol 615. 2016-07-14. PMID:26797579. |
opposite regulation of cannabinoid cb1 and cb2 receptors in the prefrontal cortex of rats treated with cocaine during adolescence. |
2016-07-14 |
2023-08-13 |
rat |
| Rubén García-Cabrerizo, M Julia García-Fuste. Opposite regulation of cannabinoid CB1 and CB2 receptors in the prefrontal cortex of rats treated with cocaine during adolescence. Neuroscience letters. vol 615. 2016-07-14. PMID:26797579. |
the endocannabinoid system is implicated in the neurobiology of cocaine addiction, although it is not clear how cocaine regulates brain cb1 and cb2 receptors, especially during adolescence, a critical moment for shaping adult response to drug use. |
2016-07-14 |
2023-08-13 |
rat |
| Huikun Wang, Tyler Treadway, Daniel P Covey, Joseph F Cheer, Carl R Lupic. Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area. Cell reports. vol 12. issue 12. 2016-07-06. PMID:26365195. |
endogenous cannabinoids (ecb) are lipid molecules released from midbrain dopamine (da) neurons that modulate cocaine's effects through poorly understood mechanisms. |
2016-07-06 |
2023-08-13 |
rat |
| Huikun Wang, Tyler Treadway, Daniel P Covey, Joseph F Cheer, Carl R Lupic. Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area. Cell reports. vol 12. issue 12. 2016-07-06. PMID:26365195. |
we find that cocaine stimulates release of the ecb, 2-arachidonoylglycerol (2-ag), in the rat ventral midbrain to suppress gabaergic inhibition of da neurons, through activation of presynaptic cannabinoid cb1 receptors. |
2016-07-06 |
2023-08-13 |
rat |
| Maria C Blanco-Gandía, Ana Mateos-García, Maria P García-Pardo, Sandra Montagud-Romero, Marta Rodríguez-Arias, José Miñarro, María A Aguila. Effect of drugs of abuse on social behaviour: a review of animal models. Behavioural pharmacology. vol 26. issue 6. 2016-05-05. PMID:26221831. |
throughout the review we will explore the most relevant studies carried out to date to evaluate the effects of alcohol, cocaine, opioids, 3,4-methylenedioxymethamphetamine (mdma), cannabinoids, nicotine and other drugs of abuse on these three paradigms, taking into account the influence of different variables, such as social history, age and type of exposure. |
2016-05-05 |
2023-08-13 |
human |
| Zuzana Justinova, Leigh V Panlilio, Guillermo Moreno-Sanz, Godfrey H Redhi, Alessia Auber, Maria E Secci, Paola Mascia, Tiziano Bandiera, Andrea Armirotti, Rosalia Bertorelli, Svetlana I Chefer, Chanel Barnes, Sevil Yasar, Daniele Piomelli, Steven R Goldber. Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 9. 2016-04-26. PMID:25754762. |
both faah inhibitors: (1) blocked faah activity in brain and liver, increasing levels of endogenous ligands for cannabinoid and α-type peroxisome proliferator-activated (ppar-α) receptors; (2) shifted nicotine self-administration dose-response functions in a manner consistent with reduced nicotine reward; (3) blocked reinstatement of nicotine seeking induced by reexposure to either nicotine priming or nicotine-associated cues; and (4) had no effect on cocaine or food self-administration. |
2016-04-26 |
2023-08-13 |
rat |
| Douglas J Roberts-Wolfe, Peter W Kaliva. Glutamate Transporter GLT-1 as a Therapeutic Target for Substance Use Disorders. CNS & neurological disorders drug targets. vol 14. issue 6. 2016-03-23. PMID:26022265. |
cocaine, opioids, ethanol, nicotine, amphetamines, and cannabinoids each affect glt-1 expression and glutamate uptake, and restoring glt-1 expression with n-acetylcysteine or ceftriaxone shows promise in correcting pre-clinical and clinical manifestations of drug addiction. |
2016-03-23 |
2023-08-13 |
Not clear |
| Luciano Rezende Vilela, Lindisley Ferreira Gomides, Bruna Araújo David, Maísa Mota Antunes, Ariane Barros Diniz, Fabrício de Araújo Moreira, Gustavo Batista Meneze. Cannabidiol rescues acute hepatic toxicity and seizure induced by cocaine. Mediators of inflammation. vol 2015. 2016-02-12. PMID:25999668. |
considering the protective role of the endocannabinoid system against cell toxicity, we hypothesized that treatment with an anandamide hydrolysis inhibitor, urb597, or with a phytocannabinoid, cannabidiol (cbd), protects against cocaine toxicity. |
2016-02-12 |
2023-08-13 |
mouse |
| Zoltán V Varga, Peter Ferdinandy, Lucas Liaudet, Pál Pache. Drug-induced mitochondrial dysfunction and cardiotoxicity. American journal of physiology. Heart and circulatory physiology. vol 309. issue 9. 2016-02-08. PMID:26386112. |
illicit drugs such as alcohol, cocaine, methamphetamine, ecstasy, and synthetic cannabinoids (spice, k2) may also induce mitochondria-related cardiotoxicity. |
2016-02-08 |
2023-08-13 |
Not clear |
| Pablo Gago-Ferrero, Viola Borova, Marilena E Dasenaki, Νikolaos S Τhomaidi. Simultaneous determination of 148 pharmaceuticals and illicit drugs in sewage sludge based on ultrasound-assisted extraction and liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry. vol 407. issue 15. 2016-02-04. PMID:25716466. |
the selected compounds belong to different classes of pharmaceuticals, including antibiotics, analgesic and/or anti-inflammatory drugs, antiepileptics, benzodiazepines, antipsychotics, and antidepressants, among others, and illicit drugs, including opiates, opioids, cocaine, amphetamines, cannabinoids, and their metabolites. |
2016-02-04 |
2023-08-13 |
Not clear |
| b' Elisabeta B\\xc4\\x83dil\\xc4\\x83, Mihaela Hostiuc, Emma Weiss, Daniela Barto\\xc5\\x9. Illicit Drugs and their Impact on Cardiovascular Pathology. Romanian journal of internal medicine = Revue roumaine de medecine interne. vol 53. issue 3. 2016-02-01. PMID:26710497.' |
this review discusses the cardiovascular effects of cocaine, opiates and opioids, cannabinoids, amphetamines, methamphetamines and hallucinogens as we consider that it is essential for a clinician to be aware of them and understand their mechanisms in order to optimize the therapeutic management. |
2016-02-01 |
2023-08-13 |
Not clear |
| Claudia Vignali, Cristiana Stramesi, Luca Morini, Paolo San Bartolomeo, Angelo Gropp. Workplace drug testing in Italy: findings about second-stage testing. Drug testing and analysis. vol 7. issue 3. 2015-12-01. PMID:24652693. |
eighty percent of them had tested positive for cannabinoids during the first level analysis, and 15.8% for cocaine. |
2015-12-01 |
2023-08-12 |
Not clear |