| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Natasha L Mason, Eef L Theunissen, Nadia R P W Hutten, Desmond H Y Tse, Stefan W Toennes, Peter Stiers, Johannes G Ramaeker. Cannabis induced increase in striatal glutamate associated with loss of functional corticostriatal connectivity. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 2. 2019-07-30. PMID:30553697. |
cannabis induced increase in striatal glutamate associated with loss of functional corticostriatal connectivity. |
2019-07-30 |
2023-08-13 |
Not clear |
| b' Eva \\xc4\\x8ce\\xc5\\xa1kov\\xc3\\xa. [Current and future pharmacotherapy of severe psychiatric disorders]. Casopis lekaru ceskych. vol 157. issue 2. 2019-04-24. PMID:29790360.' |
new treatment options not yet available include cannabidiol, glutamate modulators and nicotine receptors agonists. |
2019-04-24 |
2023-08-13 |
Not clear |
| Marco Colizzi, Sagnik Bhattacharyy. Neurocognitive effects of cannabis: Lessons learned from human experimental studies. Progress in brain research. vol 242. 2019-03-29. PMID:30471680. |
also, direct and indirect evidence supports an alteration of different neurotransmitters, such as dopamine, glutamate, and gamma-aminobutyric acid, in modulating the manifestation of neurocognitive dysfunction and psychosis in the context of both acute and chronic cannabis exposure. |
2019-03-29 |
2023-08-13 |
human |
| Silvia Rigucci, Lijing Xin, Paul Klauser, Philipp S Baumann, Luis Alameda, Martine Cleusix, Raoul Jenni, Carina Ferrari, Maurizio Pompili, Rolf Gruetter, Kim Q Do, Philippe Conu. Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex. Psychopharmacology. vol 235. issue 1. 2018-12-11. PMID:29075884. |
cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex. |
2018-12-11 |
2023-08-13 |
Not clear |
| Silvia Rigucci, Lijing Xin, Paul Klauser, Philipp S Baumann, Luis Alameda, Martine Cleusix, Raoul Jenni, Carina Ferrari, Maurizio Pompili, Rolf Gruetter, Kim Q Do, Philippe Conu. Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex. Psychopharmacology. vol 235. issue 1. 2018-12-11. PMID:29075884. |
recent studies have shown that cannabis may disrupt glutamate (glu) signaling depressing glu tone in frequent users. |
2018-12-11 |
2023-08-13 |
Not clear |
| Nadja P Maric, Milica J Jovicic, Marina Mihaljevic, Cedo Miljevi. Improving Current Treatments for Schizophrenia. Drug development research. vol 77. issue 7. 2017-11-08. PMID:27633376. |
dopamine receptor blockade is necessary but not always sufficient for antipsychotic response and improvements have been reported with molecules acting on other receptors (glutamate, glycine, cannabidiol, estrogen), intracellular signaling proteins, or products of identified risk genes. |
2017-11-08 |
2023-08-13 |
Not clear |
| Marco Colizzi, Philip McGuire, Roger G Pertwee, Sagnik Bhattacharyy. Effect of cannabis on glutamate signalling in the brain: A systematic review of human and animal evidence. Neuroscience and biobehavioral reviews. vol 64. 2016-12-27. PMID:26987641. |
here we systematically review all studies examining acute and chronic effects of cannabis or Δ9-thc on glutamate signalling in both animals and man. |
2016-12-27 |
2023-08-13 |
human |
| Marco Colizzi, Philip McGuire, Roger G Pertwee, Sagnik Bhattacharyy. Effect of cannabis on glutamate signalling in the brain: A systematic review of human and animal evidence. Neuroscience and biobehavioral reviews. vol 64. 2016-12-27. PMID:26987641. |
effect of cannabis on glutamate signalling in the brain: a systematic review of human and animal evidence. |
2016-12-27 |
2023-08-13 |
human |
| Marco Colizzi, Philip McGuire, Roger G Pertwee, Sagnik Bhattacharyy. Effect of cannabis on glutamate signalling in the brain: A systematic review of human and animal evidence. Neuroscience and biobehavioral reviews. vol 64. 2016-12-27. PMID:26987641. |
in fact, it is thought that cannabis or Δ9-thc may not act on dopamine firing directly but indirectly by altering glutamate neurotransmission. |
2016-12-27 |
2023-08-13 |
human |
| Pedro H Gobira, Luciano R Vilela, Bruno D C Gonçalves, Rebeca P M Santos, Antonio C de Oliveira, Luciene B Vieira, Daniele C Aguiar, José A Crippa, Fabricio A Moreir. Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release. Neurotoxicology. vol 50. 2016-08-24. PMID:26283212. |
cannabidiol, a cannabis sativa constituent, inhibits cocaine-induced seizures in mice: possible role of the mtor pathway and reduction in glutamate release. |
2016-08-24 |
2023-08-13 |
mouse |
| Philip Seema. Schizophrenia and dopamine receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 9. 2014-05-01. PMID:23860356. |
the elevation in apparent d2high receptors in vivo in schizophrenia matches the elevation in d2high receptors in vitro in animal models of psychosis, including dopamine-supersensitive animals pretreated with amphetamine, marijuana, or phencyclidine, or animals with gene knockouts in various neurotransmitter pathways, including those for glutamate receptors. |
2014-05-01 |
2023-08-12 |
human |
| Andrew P Prescot, Perry F Renshaw, Deborah A Yurgelun-Tod. γ-Amino butyric acid and glutamate abnormalities in adolescent chronic marijuana smokers. Drug and alcohol dependence. vol 129. issue 3. 2014-01-21. PMID:23522493. |
γ-amino butyric acid and glutamate abnormalities in adolescent chronic marijuana smokers. |
2014-01-21 |
2023-08-12 |
human |
| Andrew P Prescot, Perry F Renshaw, Deborah A Yurgelun-Tod. γ-Amino butyric acid and glutamate abnormalities in adolescent chronic marijuana smokers. Drug and alcohol dependence. vol 129. issue 3. 2014-01-21. PMID:23522493. |
the goal of this study was to investigate whether the lower acc glutamate previously reported in adolescent chronic marijuana smokers is associated with lower acc gaba levels. |
2014-01-21 |
2023-08-12 |
human |
| Andrew P Prescot, Allison E Locatelli, Perry F Renshaw, Deborah A Yurgelun-Tod. Neurochemical alterations in adolescent chronic marijuana smokers: a proton MRS study. NeuroImage. vol 57. issue 1. 2011-10-19. PMID:21349338. |
previous proton magnetic resonance spectroscopy studies have demonstrated reduced basal ganglia glutamate and dorsolateral prefrontal cortex n-acetyl aspartate levels in adult chronic marijuana users. |
2011-10-19 |
2023-08-12 |
human |
| Andrew P Prescot, Allison E Locatelli, Perry F Renshaw, Deborah A Yurgelun-Tod. Neurochemical alterations in adolescent chronic marijuana smokers: a proton MRS study. NeuroImage. vol 57. issue 1. 2011-10-19. PMID:21349338. |
the present study used proton magnetic resonance spectroscopy to determine whether reductions in glutamate, n-acetyl aspartate and/or other proton metabolite concentrations would be found in the anterior cingulate cortex (acc) of adolescent marijuana users compared with non-using controls. |
2011-10-19 |
2023-08-12 |
human |
| Pablo Pandolfo, Vasco Silveirinha, Alexandre dos Santos-Rodrigues, Laurent Venance, Catherine Ledent, Reinaldo N Takahashi, Rodrigo A Cunha, Attila Köfalv. Cannabinoids inhibit the synaptic uptake of adenosine and dopamine in the rat and mouse striatum. European journal of pharmacology. vol 655. issue 1-3. 2011-07-12. PMID:21266173. |
in the same experiments, only o-2050, cannabidiol, and win55212-3 inhibited the simultaneously measured dl-tboa-sensitive uptake of [(14)c]glutamate. |
2011-07-12 |
2023-08-12 |
mouse |
| Jaime E C Hallak, Serdar M Dursun, Daniel C Bosi, Ligia Ribeiro Horta de Macedo, João Paulo Machado-de-Sousa, João Abrão, José A S Crippa, Phillip McGuire, John H Krystal, Glen B Baker, Antonio W Zuard. The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 1. 2011-05-03. PMID:21062637. |
the interplay of cannabinoid and nmda glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. |
2011-05-03 |
2023-08-12 |
human |
| Matthijs G Bossong, Raymond J M Niesin. Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia. Progress in neurobiology. vol 92. issue 3. 2011-02-28. PMID:20624444. |
our model postulates that adolescent exposure to Δ9-tetrahydrocannabinol (thc), the primary psychoactive substance in cannabis, transiently disturbs physiological control of the endogenous cannabinoid system over glutamate and gaba release. |
2011-02-28 |
2023-08-12 |
Not clear |
| Alline Cristina Campos, Francisco Silveira Guimarãe. Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 8. 2010-01-25. PMID:19735690. |
the reasons for these curves are still unclear, but since these drugs can also activate trpv1 receptors and increase glutamate release, we hypothesized that, at high doses, cannabidiol and win 55,212-2, a cb1 receptor agonist, could activate trpv1 receptors, facilitating glutamate neurotransmission and anxiety responses. |
2010-01-25 |
2023-08-12 |
rat |
| Didier Jutras-Aswad, Jennifer A DiNieri, Tibor Harkany, Yasmin L Hur. Neurobiological consequences of maternal cannabis on human fetal development and its neuropsychiatric outcome. European archives of psychiatry and clinical neuroscience. vol 259. issue 7. 2009-11-23. PMID:19568685. |
it posits that studying in utero cannabis exposure in association with genetic mutations of neural systems that have strong relationships to endocannabinoid function, such as the dopamine, opioid, glutamate, and gaba, might help to identify individuals at risk. |
2009-11-23 |
2023-08-12 |
human |