Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
E Y Adashi, P B Jones, A J Hsue. Direct antigonadal activity of cannabinoids: suppression of rat granulosa cell functions. The American journal of physiology. vol 244. issue 2. 1983-03-17. PMID:6297308. |
treatment with related but nonpsychoactive cannabinoids (cannabidiol, cannabinol, cannabigerol, or cannabichromene) was equally effective. |
1983-03-17 |
2023-08-12 |
human |
A P Mason, M Perez-Reyes, A J McBay, R L Folt. Cannabinoids in plasma after passive inhalation of marijuana smoke. JAMA. vol 249. issue 4. 1983-02-25. PMID:6294352. |
cannabinoids in plasma after passive inhalation of marijuana smoke. |
1983-02-25 |
2023-08-12 |
Not clear |
M Perez-Reyes, S di Guiseppi, K H Davi. Passive inhalation of marijuana smoke and urinary excretion cannabinoids. JAMA. vol 249. issue 4. 1983-02-25. PMID:6848846. |
passive inhalation of marijuana smoke and urinary excretion cannabinoids. |
1983-02-25 |
2023-08-12 |
Not clear |
R L Hawk. The constituents of cannabis and the disposition and metabolism of cannabinoids. NIDA research monograph. vol 42. 1983-02-14. PMID:6294522. |
the constituents of cannabis and the disposition and metabolism of cannabinoids. |
1983-02-14 |
2023-08-12 |
Not clear |
P B Baker, T A Gough, B J Taylo. The physical and chemical features of Cannabis plants grown in the United Kingdom of Great Britain and Northern Ireland from seeds of known origin. Bulletin on narcotics. vol 34. issue 1. 1983-01-19. PMID:6291677. |
the gross physical appearance and cannabinoid patterns of many of the cannabis samples produced in the united kingdom were closely related to those of the parents. |
1983-01-19 |
2023-08-12 |
Not clear |
C E Turner, H N Elsohly, G S Lewis, I Lopez-Santibanez, J Carranz. Constituents of Cannabis sativa L., XX: the cannabinoid content of Mexican variants grown in Mexico and in Mississippi, United States of America. Bulletin on narcotics. vol 34. issue 1. 1983-01-19. PMID:6923753. |
constituents of cannabis sativa l., xx: the cannabinoid content of mexican variants grown in mexico and in mississippi, united states of america. |
1983-01-19 |
2023-08-12 |
Not clear |
M E Hei. [Cannabis and cannabinoids. Possibilities of their therapeutic use]. Fortschritte der Medizin. vol 100. issue 9. 1982-07-08. PMID:7076098. |
[cannabis and cannabinoids. |
1982-07-08 |
2023-08-12 |
Not clear |
M E Hei. [Cannabis and cannabinoids. Possibilities of their therapeutic use]. Fortschritte der Medizin. vol 100. issue 9. 1982-07-08. PMID:7076098. |
newer aspects of therapeutic potentials of cannabis and cannabinoids are reviewed. |
1982-07-08 |
2023-08-12 |
Not clear |
M E Hei. [Cannabis and cannabinoids. Possibilities of their therapeutic use]. Fortschritte der Medizin. vol 100. issue 9. 1982-07-08. PMID:7076098. |
the major active constituent of cannabis sativa, delta-9-tetrahydrocannabinol and synthetic cannabinoids are evaluated in several clinical trials on their antiemetic efficacy in cancer chemotherapy induced vomiting. |
1982-07-08 |
2023-08-12 |
Not clear |
J C Turner, J K Hemphill, P G Mahlber. Interrelationships of glandular trichomes and cannabinoid content. II. Developing vegetative leaves of Cannabis sativa L. (Cannabaceae). Bulletin on narcotics. vol 33. issue 3. 1982-06-21. PMID:6279216. |
gland number and cannabinoid content were quantified during ontogeny of vegetative leaves from three clones of cannabis. |
1982-06-21 |
2023-08-12 |
Not clear |
C E Turner, M L Mole, L Hanus, H N Elsohl. Isolation of a new cannabinoid from an Indian variant of Cannabis sativa L. Activitas nervosa superior. vol 23. issue 4. 1982-05-12. PMID:7336858. |
isolation of a new cannabinoid from an indian variant of cannabis sativa l. |
1982-05-12 |
2023-08-12 |
Not clear |
R T Henrich, T Nogawa, A Morishim. In vitro induction of segregational errors of chromosomes by natural cannabinoids in normal human lymphocytes. Environmental mutagenesis. vol 2. issue 2. 1982-04-20. PMID:6276167. |
the purpose of this study was to examine the effects of natural cannabinoids - including delta-9-tetrahydrocannabinol (thc), cannabinol (cbn), and cannabidiol (cbd) - on chromosome segregation. |
1982-04-20 |
2023-08-12 |
human |
J C Turner, J K Hemphill, P G Mahlber. Interrelationships of glandular trichomes and cannabinoid content. I: Developing pistillate bracts of Cannabis sativa L. (Cannabaceae). Bulletin on narcotics. vol 33. issue 2. 1982-02-22. PMID:6914206. |
gland number and cannabinoid content for three clones of cannabis were compared. |
1982-02-22 |
2023-08-12 |
Not clear |
D M Cocchetto, L F Cook, A E Cat. A critical review of the safety and antiemetic efficacy of delta-9-tetrahydrocannabinol. Drug intelligence & clinical pharmacy. vol 15. issue 11. 1982-01-09. PMID:6271519. |
over the past six years, both government institutions and private enterprise have expressed great interest and activity in the isolation of chemical constituents from the cannabis sativa plant and synthesis of novel cannabinoid compounds with potential medicinal uses. |
1982-01-09 |
2023-08-12 |
Not clear |
D M Cocchetto, L F Cook, A E Cat. A critical review of the safety and antiemetic efficacy of delta-9-tetrahydrocannabinol. Drug intelligence & clinical pharmacy. vol 15. issue 11. 1982-01-09. PMID:6271519. |
evaluation of the safety and antiemetic efficacy of delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid component of marijuana, comprises one of several very active areas of cannabinoid clinical research. |
1982-01-09 |
2023-08-12 |
Not clear |
J C Merritt, D D Perry, D N Russell, B F Jone. Topical delta 9-tetrahydrocannabinol and aqueous dynamics in glaucoma. Journal of clinical pharmacology. vol 21. issue S1. 1982-01-09. PMID:6271841. |
further glaucoma research should therefore proceed with marihuanas containing insignificant levels of thc (less than 0.4%) and with various local delivery systems of the ocular-active cannabinoid found in cannabis sativa. |
1982-01-09 |
2023-08-12 |
human |
S A Turkanis, R Karle. Electrophysiologic properties of the cannabinoids. Journal of clinical pharmacology. vol 21. issue S1. 1982-01-09. PMID:6271840. |
the effects of the psychoactive cannabinoid delta 9-tetrahydrocannabinol (thc) and the nonpsychoactive cannabinoid cannabidiol (cbd) were investigated comparatively on electrically caused transcallosal cortical evoked responses, electrically induced limbic after discharges, photically evoked cortical afterdischarges, spontaneous cortical focal epileptic potentials, and spinal monosynaptic reflexes. |
1982-01-09 |
2023-08-12 |
Not clear |
S A Turkanis, R Karle. Electrophysiologic properties of the cannabinoids. Journal of clinical pharmacology. vol 21. issue S1. 1982-01-09. PMID:6271840. |
the results clearly demonstrate the complexity of the cns properties of thc and the selectivity of the depressant properties of cannabidiol; moreover, the data illustrate the wide range of neuropharmacologic responses that potentially any cannabinoid can effect. |
1982-01-09 |
2023-08-12 |
Not clear |
R Karler, S A Turkani. The cannabinoids as potential antiepileptics. Journal of clinical pharmacology. vol 21. issue S1. 1982-01-09. PMID:6975285. |
comparative studies of the anticonvulsant properties of the cannabinoids and prototype antiepileptic drugs in numerous animal seizure models demonstrate that (1) as an anticonvulsant, cannabidiol (cbd), in contrast to delta 9-tetrahydrocannabinol (thc), is relatively selective in terms of both central nervous system (cns), depressant and excitatory properties; (2) the potency of cannabidiol, unlike that of phenytoin and phenobarbital, varies greatly with the species; (3) the large potency difference between the cannabinoids and the antiepileptics in the mouse appears to be due to dispositional differences, because brain concentrations of all the drugs are very similar; (4) tolerance to the anticonvulsant properties of cannabidiol is not a prominent feature; in three seizure models, tolerance developed in one, but "reverse tolerance" developed in the other two; and (5) the results of a study of the electrophysiologic mechanisms of action indicate that cannabidiol produces some unique effects and that its spectrum of antiepileptic activity may be different from that of the prototype drugs. |
1982-01-09 |
2023-08-12 |
mouse |
C E Turner, M A Elsohl. Biological activity of cannabichromene, its homologs and isomers. Journal of clinical pharmacology. vol 21. issue S1. 1982-01-09. PMID:7298870. |
cannabichromene (cbc) is one of four major cannabinoids in cannabis sativa l. and is the second most abundant cannabinoid in drug-type cannabis. |
1982-01-09 |
2023-08-12 |
rat |