Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
DaNae R Woodard, Emi Nakahara, John D Hullema. Clinically-identified C-terminal mutations in fibulin-3 are prone to misfolding and destabilization. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33542268. |
upon follow-up studies, when this conserved residue (l451) was mutated to a charged (asp or arg) or bulky (pro, trp, tyr) residue, f3 secretion was also compromised, indicating the importance of small side chains (leu, ala, or gly) at this residue. |
2021-11-15 |
2023-08-13 |
Not clear |
Min Zhang, Da Yang, Barry Gol. Origins of nonsense mutations in human tumor suppressor genes. Mutation research. vol 823. 2021-11-01. PMID:34461460. |
c•g→a•t transversions at glu, ser, tyr, gly and cys codons account for 25 % of the total nonsense mutations but the mutation per codon ratio for these codons is 1.0. |
2021-11-01 |
2023-08-13 |
human |
Zujing Chen, Yueqin Xie, Junyi Luo, Ting Chen, Qianyun Xi, Yongliang Zhang, Jiajie Su. Dietary supplementation with Moringa oleifera and mulberry leaf affects pork quality from finishing pigs. Journal of animal physiology and animal nutrition. vol 105. issue 1. 2021-10-15. PMID:33021002. |
morus also increased cp, glu, gly, ala, arg, ile, phe, pro, ser, tyr and asp, and c16:1, c18:1n9c, c20:4n6, c18:3n3, c20:3n3, c22:1n9 and n-3 pufa, but decreased c12:0 and c16:0. |
2021-10-15 |
2023-08-13 |
Not clear |
Magdalena Mierzchała-Pasierb, Małgorzata Lipińska-Gediga, Mariusz G Fleszar, Łukasz Lewandowski, Paweł Serek, Sylwia Płaczkowska, Małgorzata Krzystek-Korpack. An analysis of urine and serum amino acids in critically ill patients upon admission by means of targeted LC-MS/MS: a preliminary study. Scientific reports. vol 11. issue 1. 2021-10-13. PMID:34620961. |
on admission in the whole cohort, aaa, aba, mhis, apa, gly-pro and tpro concentrations were significantly lower in the serum than in the urine and arg, gly, his, hpro, leu, ile, lys, orn, phe, sarc, thr, tyr, asn and gln were significantly higher in the serum than in the urine. |
2021-10-13 |
2023-08-13 |
human |
Md Minhas Hossain Sakib, Aktiya Anjum Nishat, Mohammad Tarequl Islam, Mohammad Abu Raihan Uddin, Md Shahriar Iqbal, Farhan Fuad Bin Hossen, Mohammad Imran Ahmed, Md Samiul Bashir, Takbir Hossain, Umma Sumia Tohura, Saiful Islam Saif, Nabilah Rahman Jui, Mosharaf Alam, Md Aminul Islam, Md Mehadi Hasan, Md Abu Sufian, Md Ackas Ali, Rajib Islam, Mohammed Akhter Hossain, Mohammad A Hali. Computational screening of 645 antiviral peptides against the receptor-binding domain of the spike protein in SARS-CoV-2. Computers in biology and medicine. vol 136. 2021-09-17. PMID:34403938. |
the critical residues in rbd found for protein-peptide interactions are tyr 489, gly 485, tyr 505, and glu 484. |
2021-09-17 |
2023-08-13 |
human |
Wut H Phue, Mazen Bahadi, James J Dynes, Jian Wang, Venkata S C Kuppili, Ashraf Ismail, Aneela Hameed, Saji Georg. Protein-biomolecule interactions play a major role in shaping corona proteome: studies on milk interacted dietary particles. Nanoscale. vol 13. issue 31. 2021-09-07. PMID:34477741. |
results from individual protein-particle interactions revealed the significance of factors such as zeta potential, hydrophobicity and hydrodynamic size of particles, and protein characteristics such as the number of beta strands, isoelectric points, the number of amino acid units (ile, tyr, ala, gly, pro, asp, and arg), and phosphorylation sites on their adsorption to particles. |
2021-09-07 |
2023-08-13 |
human |
Li Qu, Shuqing Gu, Jiaqi Zhang, Chaomin Zhao, Xiaojun Den. [Determination of 18 amino acids in three different kinds of milk powder by ultra performance liquid chromatography coupled with pre-column derivatization]. Se pu = Chinese journal of chromatography. vol 39. issue 5. 2021-07-27. PMID:34227331. |
in this paper, a method was developed for the simultaneous determination of 18 amino acids (aas), histidine (his), serine (ser), arginine (arg), glycine (gly), aspartic acid (asp) combined with asparagine (asn), glutamic (glu), glutamine (gln), threonine (thr), alanine (ala), proline (pro), lysine (lys), tyrosine (tyr), methionine (met), valine (val), isoleucine (iso), leucine (leu), and dimer of cysteine (cys) combined with cysteine (l-cys-cys), phenylalanine (phe), taurine (tau) in milk, goat milk, and camel milk power. |
2021-07-27 |
2023-08-13 |
Not clear |
Luping Hu, Tao Zheng, Yanxi Song, Ji Fan, Hongqi Li, Ruiqing Zhang, Yi Su. Ultrasensitive and selective fluorescent sensor for cysteine and application to drug analysis and bioimaging. Analytical biochemistry. vol 620. 2021-07-06. PMID:33639112. |
addition of cys to the non-fluorescent sensor solution in dmf induced bright blue fluorescence and enhanced the fluorescence intensity by 320-fold while other amino acids and biothiols (gly, hcy, gsh, glu, val, tyr, arg, trp, lys, his, leu, phe, asp and met) did not bring about remarked change. |
2021-07-06 |
2023-08-13 |
Not clear |
M Terré, I Ortuzar, J Graffelman, A Bassols, M Vidal, A Bac. Using compositional mixed-effects models to evaluate responses to amino acid supplementation in milk replacers for calves. Journal of dairy science. vol 104. issue 7. 2021-06-22. PMID:33865583. |
the 4 mr were as follows: ctrl with no aa supplementation; pg, supplying additional 0.3% pro and 0.1% gly; fy, supplying additional 0.2% phe and 0.2% tyr; and kmt, providing additional 0.62% lys, 0.22% met, and 0.61% thr. |
2021-06-22 |
2023-08-13 |
Not clear |
Iris Álvarez-Merz, Javier G Luengo, María-Dolores Muñoz, Jesús M Hernández-Guijo, José M Solí. Hypoxia-induced depression of synaptic transmission becomes irreversible by intracellular accumulation of non-excitatory amino acids. Neuropharmacology. vol 190. 2021-06-09. PMID:33848510. |
we applied a mixture of 19 aas at their plasmatic concentrations (plasma solution: ala, gly, gln, his, ser, tau, thr, arg, leu, met, pro, val, asn, cys, phe, ile, lys, tyr, and trp). |
2021-06-09 |
2023-08-13 |
rat |
Tatsuhiko Goto, Saki Shimamoto, Akira Ohtsuka, Daichi Ijir. Analyses of free amino acid and taste sensor traits in egg albumen and yolk revealed potential of value-added eggs in chickens. Animal science journal = Nihon chikusan Gakkaiho. vol 92. issue 1. 2021-05-31. PMID:33417307. |
significant breed effects were detected in four albumen amino acid traits (his, met, ile, and lys) and a yolk his, whereas significant feed effects were found in 15 albumen amino acid traits (asp, glu, ser, his, gly, thr, ala, tyr, val, met, trp, ile, leu, lys, and pro) and a yolk cystine trait. |
2021-05-31 |
2023-08-13 |
chicken |
Sérgio R S Veloso, Peter J Jervis, Joana F G Silva, Loic Hilliou, C Moura, David M Pereira, Paulo J G Coutinho, J A Martins, Elisabete M S Castanheira, Paula M T Ferreir. Supramolecular ultra-short carboxybenzyl-protected dehydropeptide-based hydrogels for drug delivery. Materials science & engineering. C, Materials for biological applications. vol 122. 2021-05-14. PMID:33641890. |
in this work a focused library of cbz-protected dehydrodipeptides cbz-l-xaa-z-Δphe-oh (xaa= met, phe, tyr, ala, gly) was synthesised and evaluated as minimalist hydrogels. |
2021-05-14 |
2023-08-13 |
Not clear |
M J Chen, Z Fu, S G Jiang, X Q Wang, H C Yan, C Q Ga. Targeted disruption of TORC1 retards young squab growth by inhibiting the synthesis of crop milk protein in breeding pigeon (Columba livia). Poultry science. 2021-04-12. PMID:31504948. |
simultaneously, rapa (especially at 1.2 mg/kg bw) decreased the crude protein, αs1-casein, αs2-casein, β-casein, and amino acid contents (asp, thr, ser, glu, gly, ala, cys, val, met, ile, leu, tyr, lys, his, arg, and pro) of crop milk (p < 0.05) and the concentrations of albumin, total protein, and uric acid in the serum of breeding pigeons (p < 0.05). |
2021-04-12 |
2023-08-13 |
pigeon |
Behzad Sadighi Sheikhhasan, Hossein Moravej, Fateme Ghaziani, Enric Esteve-Garcia, Woo Kyun Ki. Relationship between chemical composition and standardized ileal digestible amino acid contents of corn grain in broiler chickens. Poultry science. vol 99. issue 9. 2021-03-19. PMID:32867993. |
there was significant variation among the 4 corn grains in standardized ileal digestibility (sid) for cp, phe, leu, asp, glu, ser, gly, ala, and tyr (p ≤ 0.05). |
2021-03-19 |
2023-08-13 |
Not clear |
Ana Clara B Menezes, Kacie L McCarthy, Cierrah J Kassetas, Friederike Baumgaertner, James D Kirsch, Sheri Dorsam, Tammi L Neville, Alison K Ward, Pawel P Borowicz, Lawrence P Reynolds, Kevin K Sedivec, J Chris Forcherio, Ronald Scott, Joel S Caton, Carl R Dahle. Vitamin and mineral supplementation and rate of gain during the first trimester of gestation affect concentrations of amino acids in maternal serum and allantoic fluid of beef heifers. Journal of animal science. vol 99. issue 2. 2021-02-24. PMID:33493276. |
samples were analyzed for concentrations of neutral aa: ala, asn, cys, gln, gly, ile, leu, met, phe, pro, ser, thr, trp, tyr, and val; cationic aa: arg, his, and lys; and anionic aa: asp and glu. |
2021-02-24 |
2023-08-13 |
cattle |
Nattapol Arunrattanamook, Rungtiva Wansuksri, Tanaporn Uengwetwanit, Verawat Champred. Engineering of β-mannanase from Aspergillus niger to increase product selectivity towards medium chain length mannooligosaccharides. Journal of bioscience and bioengineering. vol 130. issue 5. 2020-11-19. PMID:32727668. |
tyr 42 and tyr 132 were mutated to gly to extend the substrate binding site, allowing higher molecular weight mos to non-catalytically bind to the enzyme. |
2020-11-19 |
2023-08-13 |
Not clear |
Surid Mohammad Chowdhury, Shafi Ahmad Talukder, Akib Mahmud Khan, Nadia Afrin, Md Ackas Ali, Rajib Islam, Rimon Parves, Abdulla Al Mamun, Md Abu Sufian, Md Nayeem Hossain, Mohammed Akhter Hossain, Mohammad A Hali. Antiviral Peptides as Promising Therapeutics against SARS-CoV-2. The journal of physical chemistry. B. vol 124. issue 44. 2020-11-17. PMID:33095007. |
structure-activity relationship indicated that peptides containing aromatic (tyr and phe), nonpolar (pro, gly, leu, and ala), and polar (asn, gln, and cys) residues were the most significant contributors. |
2020-11-17 |
2023-08-13 |
human |
Takuya Yoshizawa, Hiroyoshi Matsumur. Effect of nuclear import receptors on liquid-liquid phase separation. Biophysics and physicobiology. vol 17. 2020-10-29. PMID:33110735. |
the n-terminal lc sequence of fus is made up of ser, tyr, gly, and gln, which form a labile cross-β polymer core while the c-terminal arg-gly-gly repeats accelerate llps. |
2020-10-29 |
2023-08-13 |
Not clear |
Rajneesh, Jainendra Pathak, Vinod K Kannaujiya, Shailendra P Singh, Rajeshwar P Sinh. Codon usage analysis of photolyase encoding genes of cyanobacteria inhabiting diverse habitats. 3 Biotech. vol 7. issue 3. 2020-09-28. PMID:28664377. |
however, second position (g2c2) of codon regulates variation of ala, cys, gly, pro, arg, ser, thr and tyr contents in photolyases. |
2020-09-28 |
2023-08-13 |
Not clear |
Rajneesh, Jainendra Pathak, Vinod K Kannaujiya, Shailendra P Singh, Rajeshwar P Sinh. Codon usage analysis of photolyase encoding genes of cyanobacteria inhabiting diverse habitats. 3 Biotech. vol 7. issue 3. 2020-09-28. PMID:28664377. |
third position (g3c3) of codon controls incorporation of amino acids such as ala, phe, gly, leu, gln, pro, arg, ser, thr and tyr in photolyases from three habitats. |
2020-09-28 |
2023-08-13 |
Not clear |