Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Rodger A Liddl. The role of Transient Receptor Potential Vanilloid 1 (TRPV1) channels in pancreatitis. Biochimica et biophysica acta. vol 1772. issue 8. 2007-09-28. PMID:17428642. |
recent studies indicate that primary sensory neurons of the pancreas express transient receptor potential v1 (trpv1) channels whose activation induces pancreatic inflammation. |
2007-09-28 |
2023-08-12 |
Not clear |
Toshio Ohta, Toshiaki Imagawa, Shigeo It. Novel agonistic action of mustard oil on recombinant and endogenous porcine transient receptor potential V1 (pTRPV1) channels. Biochemical pharmacology. vol 73. issue 10. 2007-06-04. PMID:17328867. |
we have characterized the action of mo on transient receptor potential v1 (trpv1), a key receptor of signal transduction pathways in the nociceptive system, using fura-2-based [ca(2+)](i) imaging and the patch-clamp technique in a heterologous expression system and sensory neurons. |
2007-06-04 |
2023-08-12 |
human |
Gisela Segond von Banchet, Jonny Richter, Marion Hückel, Christina Rose, Rolf Bräuer, Hans-Georg Schaibl. Fibroblast-like synovial cells from normal and inflamed knee joints differently affect the expression of pain-related receptors in sensory neurones: a co-culture study. Arthritis research & therapy. vol 9. issue 1. 2007-04-30. PMID:17254343. |
in addition, the expression of the transient receptor potential v1 (trpv1) receptor, which is involved in inflammation-evoked thermal hyperalgesia, was mainly upregulated by co-culturing drg neurones with fls cells from chronically inflamed joints. |
2007-04-30 |
2023-08-12 |
rat |
Andriani Athanasiou, Paul A Smith, Sara Vakilpour, Nethia M Kumaran, Amy E Turner, Dimitra Bagiokou, Robert Layfield, David E Ray, Andrew D Westwell, Stephen P H Alexander, David A Kendall, Dileep N Lobo, Susan A Watson, Artitaya Lophatanon, Kenneth A Muir, De-An Guo, Timothy E Bate. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and biophysical research communications. vol 354. issue 1. 2007-04-06. PMID:17214968. |
time-lapse photomicroscopy of human h460 lung cancer cells demonstrated of the transient receptor potential v1 (trpv1) channel agonists, (e)-capsaicin and resiniferatoxin, and the trpv1 antagonists, capsazepine, and sb366791, were able to bring about morphological changes characteristic of apoptosis and/or necrosis. |
2007-04-06 |
2023-08-12 |
human |
Andriani Athanasiou, Paul A Smith, Sara Vakilpour, Nethia M Kumaran, Amy E Turner, Dimitra Bagiokou, Robert Layfield, David E Ray, Andrew D Westwell, Stephen P H Alexander, David A Kendall, Dileep N Lobo, Susan A Watson, Artitaya Lophatanon, Kenneth A Muir, De-An Guo, Timothy E Bate. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and biophysical research communications. vol 354. issue 1. 2007-04-06. PMID:17214968. |
immunoblot analysis identified immunoreactivity for the transient receptor potential v1 (trpv1) channel in rat brain samples, but not in rat heart mitochondria or in h460 cells. |
2007-04-06 |
2023-08-12 |
human |
Toshio Ohta, Yuki Ikemi, Matsuka Murakami, Toshiaki Imagawa, Ken-Ichi Otsuguro, Shigeo It. Potentiation of transient receptor potential V1 functions by the activation of metabotropic 5-HT receptors in rat primary sensory neurons. The Journal of physiology. vol 576. issue Pt 3. 2007-03-05. PMID:16901936. |
transient receptor potential v1 (trpv1) plays a pivotal role in nociceptive receptors. |
2007-03-05 |
2023-08-12 |
rat |
Nathaniel A Jeske, Amol M Patwardhan, Nikita Gamper, Theodore J Price, Armen N Akopian, Kenneth M Hargreave. Cannabinoid WIN 55,212-2 regulates TRPV1 phosphorylation in sensory neurons. The Journal of biological chemistry. vol 281. issue 43. 2006-12-07. PMID:16954222. |
because phosphorylation of trpv1 (transient receptor potential subtype v1) plays a key role in the induction of thermal hyperalgesia in inflammatory pain models, we evaluated whether the cannabinoid agonist win 55,212-2 (win) regulates the phosphorylation state of trpv1. |
2006-12-07 |
2023-08-12 |
rat |
Juliana L Maia, Roberto C P Lima-Júnior, Caroline M Melo, Juceni P David, Jorge M David, Adriana R Campos, Flávia A Santos, Vietla S N Ra. Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms. Pharmacological research. vol 54. issue 4. 2006-11-07. PMID:16879974. |
ruthenium red (3 mgkg(-1), s.c.), a non-competitive vanilloid receptor (v1, trpv1)-antagonist also suppressed the capsaicin nociception by 38.6%. |
2006-11-07 |
2023-08-12 |
mouse |
Roberto C P Lima-Júnior, Francisco A Oliveira, Luilma A Gurgel, Italo J Cavalcante, Kelcyana A Santos, Deive A Campos, Cinthia A Vale, Regilane M Silva, Mariana H Chaves, Vietla S N Rao, Flávia A Santo. Attenuation of visceral nociception by alpha- and beta-amyrin, a triterpenoid mixture isolated from the resin of Protium heptaphyllum, in mice. Planta medica. vol 72. issue 1. 2006-04-27. PMID:16450293. |
while pretreatment with ruthenium red (3 mg/kg, s. c.), a non-specific transient receptor potential cation channel v1 (trpv1) antagonist, also caused significant inhibition, the alpha (2)-adrenoceptor antagonist, yohimbine (2 mg/kg, s. c.), showed no significant effect. |
2006-04-27 |
2023-08-12 |
mouse |
Luciano De Petrocellis, Vincenzo Di Marz. Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels. Life sciences. vol 77. issue 14. 2006-01-05. PMID:15936040. |
lipids as regulators of the activity of transient receptor potential type v1 (trpv1) channels. |
2006-01-05 |
2023-08-12 |
Not clear |
Rachid El Kouhen, Carol S Surowy, Bruce R Bianchi, Torben R Neelands, Heath A McDonald, Wende Niforatos, Arthur Gomtsyan, Chih-Hung Lee, Prisca Honore, James P Sullivan, Michael F Jarvis, Connie R Faltyne. A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel and selective transient receptor potential type V1 receptor antagonist, blocks channel activation by vanilloids, heat, and acid. The Journal of pharmacology and experimental therapeutics. vol 314. issue 1. 2005-08-26. PMID:15837819. |
the vanilloid receptor transient receptor potential type v1 (trpv1) integrates responses to multiple stimuli, such as capsaicin, acid, heat, and endovanilloids and plays an important role in the transmission of inflammatory pain. |
2005-08-26 |
2023-08-12 |
human |
Luciano De Petrocellis, Constance J Chu, Aniello Schiano Moriello, Juliane C Kellner, J Michael Walker, Vincenzo Di Marz. Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels. British journal of pharmacology. vol 143. issue 2. 2005-04-22. PMID:15289293. |
two unsaturated members of this family of lipids, n-arachidonoyl-dopamine (nada) and n-oleoyl-dopamine, were shown to potently activate the transient receptor potential channel type v1 (trpv1), also known as the vanilloid receptor type 1 for capsaicin. |
2005-04-22 |
2023-08-12 |
human |
Craig C Correll, P Tara Phelps, John C Anthes, Shelby Umland, Scott Greenfede. Cloning and pharmacological characterization of mouse TRPV1. Neuroscience letters. vol 370. issue 1. 2005-01-31. PMID:15489017. |
the transient receptor potential cation channel v1 (trpv1) is expressed in peripheral nociceptive neurons and is subject to polymodal activation via various agents including capsaicin, noxious heat, low extracellular ph, and direct phosphorylation by protein kinase c (pkc). |
2005-01-31 |
2023-08-12 |
mouse |
Tomoko Moriyama, Tohko Iida, Kimiko Kobayashi, Tomohiro Higashi, Tetsuo Fukuoka, Hideki Tsumura, Catherine Leon, Noboru Suzuki, Kazuhide Inoue, Christian Gachet, Koichi Noguchi, Makoto Tominag. Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 14. 2003-08-07. PMID:12853424. |
the capsaicin receptor transient receptor potential v1 (trpv1; also known as vanilloid receptor 1) is a sensory neuron-specific ion channel that serves as a polymodal detector of pain-producing chemical and physical stimuli. |
2003-08-07 |
2023-08-12 |
mouse |