| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Patil, N A Jeske, A N Akopia. Transient receptor potential V1 regulates activation and modulation of transient receptor potential A1 by Ca2+. Neuroscience. vol 171. issue 4. 2011-03-10. PMID:20884333. |
since trpa1 and transient receptor potential v1 (trpv1) channels are co-expressed and interact in neurons, we investigated whether activation and modulation of trpa1 by ca(2+) is regulated by trpv1. |
2011-03-10 |
2023-08-12 |
Not clear |
| Joshua P Prage. What does the mechanism of spinal cord stimulation tell us about complex regional pain syndrome? Pain medicine (Malden, Mass.). vol 11. issue 8. 2011-01-13. PMID:20704677. |
cutaneous vasodilation following scs in animal models has been shown to involve antidromic release of calcitonin gene-related peptide and possibly nitric oxide, from small-diameter sensory neurons expressing the transient receptor potential v1 (trpv1) receptor. |
2011-01-13 |
2023-08-12 |
Not clear |
| V Di Marzo, L De Petrocelli. Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs. Current medicinal chemistry. vol 17. issue 14. 2010-07-28. PMID:20166923. |
these experiments were initially based on the observation that the endocannabinoid anandamide and the xenobiotic ligand of trp channels of v1 type (trpv1), capsaicin, are somehow chemically similar, both compounds being fatty acid amides, as are also synthetic activators of these channels and inhibitors of anandamide cellular re-uptake. |
2010-07-28 |
2023-08-12 |
Not clear |
| G A Buznikov, L A Nikitina, V V Bezuglov, M E Y Francisco, G Boysen, I N Obispo-Peak, R E Peterson, E R Weiss, H Schuel, B R S Temple, A L Morrow, J M Laude. A putative 'pre-nervous' endocannabinoid system in early echinoderm development. Developmental neuroscience. vol 32. issue 1. 2010-07-09. PMID:19907129. |
cb1 antagonists, aea transport inhibitors, and the cation channel transient membrane potential receptor v1 (trpv1) agonist, arachidonoyl vanillic acid (arvanil), as well as arachidonoyl serotonin and dopamine (aa-5-ht, aa-da) acted as rescue substances, partially or totally preventing abnormal embryonic phenotypes elicited by aea or cp55940. |
2010-07-09 |
2023-08-12 |
Not clear |
| Y Kajihara, M Murakami, T Imagawa, K Otsuguro, S Ito, T Oht. Histamine potentiates acid-induced responses mediating transient receptor potential V1 in mouse primary sensory neurons. Neuroscience. vol 166. issue 1. 2010-05-04. PMID:20006972. |
in capsaicin-sensitive drg neurons from wild-type mice, acid (>ph 5.0) evoked [ca(2+)](i) increases, but not in drg neurons from transient receptor potential v1 (trpv1) (-/-) mice. |
2010-05-04 |
2023-08-12 |
mouse |
| Hideki Kobayashi, Mitsuharu Yoshiyama, Hidenori Zakoji, Masayuki Takeda, Isao Arak. Sex differences in the expression profile of acid-sensing ion channels in the mouse urinary bladder: a possible involvement in irritative bladder symptoms. BJU international. vol 104. issue 11. 2010-02-17. PMID:19493263. |
asic and transient receptor potential channel v1, trpv1; both key receptors for extracellular protons that might underlie the acid-evoked pain perception) and other nociceptive ion channels in the mouse bladder. |
2010-02-17 |
2023-08-12 |
mouse |
| Jun-ichi Satoh, Michiaki Yamakag. Desflurane induces airway contraction mainly by activating transient receptor potential A1 of sensory C-fibers. Journal of anesthesia. vol 23. issue 4. 2010-01-26. PMID:19921381. |
a transient receptor potential a1 (trpa1) or a transient receptor potential v1 (trpv1) selective antagonist of sensory c-fibers, i.e., hc030031 or bctc, was administered before the exposure to desflurane. |
2010-01-26 |
2023-08-12 |
Not clear |
| C Robin Hile. Endocannabinoids and the heart. Journal of cardiovascular pharmacology. vol 53. issue 4. 2009-07-16. PMID:19276990. |
they activate cannabinoid cb1 and cb2 receptors, transient receptor potential v1 (trpv1), peroxisome proliferator-activated receptors, and perhaps a novel vascular g-protein-coupled receptor. |
2009-07-16 |
2023-08-12 |
mouse |
| S K Suckow, R M Caudl. Identification and immunohistochemical characterization of colospinal afferent neurons in the rat. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18424003. |
however they did not express the transient receptor potential receptor v1 (trpv1) or neurokinin 1 receptor (nk1). |
2009-06-08 |
2023-08-12 |
rat |
| Josef Donnerer, Ingrid Liebmann, Rufina Schuligo. Capsaicin- and mustard oil-induced extracellular signal-regulated protein kinase phosphorylation in sensory neurons in vivo: effects of neurokinins 1 and 2 receptor antagonists and of a nitric oxide synthase inhibitor. Basic & clinical pharmacology & toxicology. vol 104. issue 1. 2009-03-26. PMID:19152548. |
stimulation of primary sensory neurons with capsaicin or mustard oil leads to phosphorylation of extracellular signal-regulated protein kinase 1/2 (p-erk1/2) via activation of transient receptor potential v1 (trpv1) or trpa1, respectively. |
2009-03-26 |
2023-08-12 |
rat |
| Toshio Ohta, Toshiaki Imagawa, Shigeo It. Involvement of transient receptor potential vanilloid subtype 1 in analgesic action of methylsalicylate. Molecular pharmacology. vol 75. issue 2. 2009-02-23. PMID:18987162. |
here we characterize the action of ms on transient receptor potential v1 (trpv1). |
2009-02-23 |
2023-08-12 |
human |
| Heath A McDonald, Torben R Neelands, Michael Kort, Ping Han, Melissa H Vos, Connie R Faltynek, Robert B Moreland, Pamela S Puttfarcke. Characterization of A-425619 at native TRPV1 receptors: a comparison between dorsal root ganglia and trigeminal ganglia. European journal of pharmacology. vol 596. issue 1-3. 2009-01-12. PMID:18755179. |
1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea (a-425619), a novel, potent, and selective transient receptor potential type v1 (trpv1) antagonist, attenuates pain associated with inflammation and tissue injury in rats. |
2009-01-12 |
2023-08-12 |
rat |
| Yun Wan. The functional regulation of TRPV1 and its role in pain sensitization. Neurochemical research. vol 33. issue 10. 2008-12-08. PMID:18528757. |
transient receptor potential v1 (trpv1) is specifically expressed in the nociceptive receptors and can detect a variety of noxious stimuli, thus potentiating pain sensitization. |
2008-12-08 |
2023-08-12 |
Not clear |
| Haihao Zhu, Yanrui Yang, Hua Zhang, Yan Han, Yafang Li, Ying Zhang, Dongmin Yin, Qihua He, Zhiqi Zhao, Peter M Blumberg, Jisheng Han, Yun Wan. Interaction between protein kinase D1 and transient receptor potential V1 in primary sensory neurons is involved in heat hypersensitivity. Pain. vol 137. issue 3. 2008-10-06. PMID:18063480. |
in previous studies we demonstrated that protein kinase d1 (pkd1/pkcmu) could directly phosphorylate the transient receptor potential v1 (trpv1) at its n-terminal region and enhance the function of trpv1 in cho cells stably transfected with trpv1. |
2008-10-06 |
2023-08-12 |
rat |
| Larry V Pearce, Attila Toth, HyungChul Ryu, Dong Wook Kang, Hyun-Kyung Choi, Mi-Kyoung Jin, Jeewoo Lee, Peter M Blumber. Differential modulation of agonist and antagonist structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitors. Naunyn-Schmiedeberg's archives of pharmacology. vol 377. issue 2. 2008-08-21. PMID:18259730. |
the transient receptor potential v1 channel (vanilloid receptor, trpv1) represents a promising therapeutic target for inflammatory pain and other conditions involving c-fiber sensory afferent neurons. |
2008-08-21 |
2023-08-12 |
human |
| Otilia Obreja, Andreas Klusch, Norbert Ponelies, Martin Schmelz, Marlen Peterse. A subpopulation of capsaicin-sensitive porcine dorsal root ganglion neurons is lacking hyperpolarization-activated cyclic nucleotide-gated channels. European journal of pain (London, England). vol 12. issue 6. 2008-08-20. PMID:18218331. |
single labeling revealed capsaicin-induced cobalt-uptake in 54.3% and transient receptor potential v1 (trpv1) immunoreactivity in 55.1% of all neurons. |
2008-08-20 |
2023-08-12 |
Not clear |
| Toshio Ohta, Toshiaki Imagawa, Shigeo It. Novel gating and sensitizing mechanism of capsaicin receptor (TRPV1): tonic inhibitory regulation of extracellular sodium through the external protonation sites on TRPV1. The Journal of biological chemistry. vol 283. issue 14. 2008-05-22. PMID:18230619. |
transient receptor potential v1 (trpv1) is a nonselective cation channel expressed in nociceptors and activated by capsaicin. |
2008-05-22 |
2023-08-12 |
mouse |
| Tamás Kark, Zsolt Bagi, Erzsébet Lizanecz, Eniko T Pásztor, Nóra Erdei, Agnes Czikora, Zoltán Papp, István Edes, Róbert Pórszász, Attila Tót. Tissue-specific regulation of microvascular diameter: opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1. Molecular pharmacology. vol 73. issue 5. 2008-05-06. PMID:18256211. |
the transient receptor potential type v1 channel (vanilloid receptor 1, trpv1) is a ca(2+)-permeable nonspecific cation channel activated by various painful stimuli including ischemia. |
2008-05-06 |
2023-08-12 |
mouse |
| Nikita B Ruparel, Amol M Patwardhan, Armen N Akopian, Kenneth M Hargreave. Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors. Pain. vol 135. issue 3. 2008-05-02. PMID:17590514. |
the transient receptor potential channel subtypes v1 (trpv1) and a1 (trpa1) play a critical role in the development of hyperalgesia in inflammatory pain models. |
2008-05-02 |
2023-08-12 |
rat |
| Xuehong Cao, Xuesong Cao, Hong Xie, Rong Yang, Gang Lei, Fen Li, Ai Li, Changjin Liu, Lieju Li. Effects of capsaicin on VGSCs in TRPV1-/- mice. Brain research. vol 1163. 2007-10-19. PMID:17632091. |
two different mechanisms by which capsaicin blocks voltage-gated sodium channels (vgscs) were found by using knockout mice for the transient receptor potential v1 (trpv1(-/-)). |
2007-10-19 |
2023-08-12 |
mouse |