All Relations between tph1 and serotonin

Publication Sentence Publish Date Extraction Date Species
Jeffrey McKinney, Per M Knappskog, Jan Haavi. Different properties of the central and peripheral forms of human tryptophan hydroxylase. Journal of neurochemistry. vol 92. issue 2. 2005-05-26. PMID:15663479. the differences between tph1 and tph2 have important implications for the regulation of serotonin production in the brain and the periphery and may provide an explanation for some of the diverging results reported for tph from different sources in the past. 2005-05-26 2023-08-12 human
M Reuter, J Henni. Pleiotropic effect of the TPH A779C polymorphism on nicotine dependence and personality. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 134B. issue 1. 2005-05-09. PMID:15635702. recent studies from molecular genetics have suggested an association between the tryptophan hydroxylase 1 (tph1) gene and nicotine addiction indicating a dysfunction of the serotonergic (5-ht) system in smoking behavior. 2005-05-09 2023-08-12 human
H S Sun, H-W Tsai, H-C Ko, F-M Chang, T-L Ye. Association of tryptophan hydroxylase gene polymorphism with depression, anxiety and comorbid depression and anxiety in a population-based sample of postpartum Taiwanese women. Genes, brain, and behavior. vol 3. issue 6. 2005-03-15. PMID:15544576. since tryptophan hydroxylase (tph1) is the rate-limiting enzyme in serotonin biosynthesis, its role in the pathophysiology of these psychiatric diseases has been intensively studied. 2005-03-15 2023-08-12 human
Francine Côté, Cécile Fligny, Jacques Mallet, Guilan Vodjdan. [Abnormal cardiac activity in mice in the absence of peripheral serotonin synthesis]. Journal de la Societe de biologie. vol 198. issue 1. 2004-07-19. PMID:15146950. the rate limiting enzyme of 5-ht synthesis, tryptophan hydroxylase (tph), is encoded by two genes: the well characterized tph1 gene and a recently identified tph2 gene. 2004-07-19 2023-08-12 mouse
Francine Côté, Cécile Fligny, Jacques Mallet, Guilan Vodjdan. [Abnormal cardiac activity in mice in the absence of peripheral serotonin synthesis]. Journal de la Societe de biologie. vol 198. issue 1. 2004-07-19. PMID:15146950. this is the first report linking loss of tph1 gene expression, and thus of peripheral 5-ht, to a cardiac dysfunction phenotype. 2004-07-19 2023-08-12 mouse
Francine Côté, Etienne Thévenot, Cécile Fligny, Yves Fromes, Michèle Darmon, Marie-Anne Ripoche, Elisa Bayard, Naima Hanoun, Francoise Saurini, Philippe Lechat, Luisa Dandolo, Michel Hamon, Jacques Mallet, Guilan Vodjdan. Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 23. 2004-01-05. PMID:14597720. disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. 2004-01-05 2023-08-12 mouse
Francine Côté, Etienne Thévenot, Cécile Fligny, Yves Fromes, Michèle Darmon, Marie-Anne Ripoche, Elisa Bayard, Naima Hanoun, Francoise Saurini, Philippe Lechat, Luisa Dandolo, Michel Hamon, Jacques Mallet, Guilan Vodjdan. Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 23. 2004-01-05. PMID:14597720. the rate-limiting enzyme of 5-ht synthesis, tryptophan hydroxylase (tph), is encoded by two genes, the well characterized tph1 gene and a recently identified tph2 gene. 2004-01-05 2023-08-12 mouse
Francine Côté, Etienne Thévenot, Cécile Fligny, Yves Fromes, Michèle Darmon, Marie-Anne Ripoche, Elisa Bayard, Naima Hanoun, Francoise Saurini, Philippe Lechat, Luisa Dandolo, Michel Hamon, Jacques Mallet, Guilan Vodjdan. Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 23. 2004-01-05. PMID:14597720. this report links loss of tph1 gene expression, and thus of peripheral 5-ht, to a cardiac dysfunction phenotype. 2004-01-05 2023-08-12 mouse
David Sugde. Comparison of circadian expression of tryptophan hydroxylase isoform mRNAs in the rat pineal gland using real-time PCR. Journal of neurochemistry. vol 86. issue 5. 2003-11-12. PMID:12911638. as serotonin (5-ht) has an important role as a precursor of the nocturnal synthesis of the pineal gland hormone, melatonin, it was of interest to determine the relative expression of tph1 and 2 mrna in the rat pineal during the light:dark (l:d) cycle using sensitive real-time rt-pcr assays which were developed for each tph isoform. 2003-11-12 2023-08-12 rat