| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shalini Dasari, Ankita Choudhary, Bhushan Madk. Psoriasis: A Primer for General Physicians. Cureus. vol 15. issue 4. 2023-05-25. PMID:37228538. |
these have been supported by the efficacy of biological therapies including tnf alpha inhibitors and inhibitors of il17 and il23. |
2023-05-25 |
2023-08-14 |
Not clear |
| Subulade A Ademola, Oluwayemi J Bamikole, Olukemi K Amod. Is TNF alpha a mediator in the co-existence of malaria and type 2 diabetes in a malaria endemic population? Frontiers in immunology. vol 14. 2023-05-23. PMID:37215099. |
is tnf alpha a mediator in the co-existence of malaria and type 2 diabetes in a malaria endemic population? |
2023-05-23 |
2023-08-14 |
Not clear |
| Lana Frankle, Amanda Riley, Riely Tomor, Hannah Lee, Kole Jarzembak, Olesia Benedict, Sarah Sternbach, John Shelestak, Jennifer McDonough, Robert Clement. Changes to Astrocyte-associated Protein Expression at Different Timepoints of Cuprizone Treatment. bioRxiv : the preprint server for biology. 2023-05-03. PMID:37131767. |
the authors also found the increase in two a1 associated proteins (tnf alpha and c3d) did not show a linear relationship in line with findings from other research and indicating a more complex relationship between cuprizone toxicity and astrocyte activation. |
2023-05-03 |
2023-08-14 |
Not clear |
| Lana Frankle, Amanda Riley, Riely Tomor, Hannah Lee, Kole Jarzembak, Olesia Benedict, Sarah Sternbach, John Shelestak, Jennifer McDonough, Robert Clement. Changes to Astrocyte-associated Protein Expression at Different Timepoints of Cuprizone Treatment. bioRxiv : the preprint server for biology. 2023-05-03. PMID:37131767. |
the increases in tnf alpha and ifn gamma did not occur at timepoints preceding increases in c3d and emp1, showing that other factors also precipitate the subtypes associated (a1 for c3d and a2 for emp1). |
2023-05-03 |
2023-08-14 |
Not clear |
| Bader Shirah, Samaher Altwirgi, Irfan Faridoon, Saeed Alghamd. Adalimumab-induced central nervous system demyelination in a patient with rheumatoid arthritis. The neuroradiology journal. 2023-05-01. PMID:37125695. |
adalimumab (humira) is a human monoclonal antibody that belongs to the tumor necrosis factor (tnf) alpha antagonist class of medications. |
2023-05-01 |
2023-08-14 |
human |
| Andrew M Joseph, Monica Karas, Cesar E Jara Silva, Melissa Leyva, Abdus Salam, Mehul Sinha, Yonathan Aliye Asfaw, Ayesha Fonseca, Steven Cordova, Marlon Reyes, Jonathan Quinonez, Samir Ruxmoha. The Potential Role of Etanercept in the Management of Post-stroke Pain: A Literature Review. Cureus. vol 15. issue 3. 2023-04-17. PMID:37065345. |
excess production of tumor necrosis factor alpha (tnf alpha) in the cerebrospinal fluid (csf) of stroke survivors has been implicated in post-stroke pain. |
2023-04-17 |
2023-08-14 |
Not clear |
| Andrew M Joseph, Monica Karas, Cesar E Jara Silva, Melissa Leyva, Abdus Salam, Mehul Sinha, Yonathan Aliye Asfaw, Ayesha Fonseca, Steven Cordova, Marlon Reyes, Jonathan Quinonez, Samir Ruxmoha. The Potential Role of Etanercept in the Management of Post-stroke Pain: A Literature Review. Cureus. vol 15. issue 3. 2023-04-17. PMID:37065345. |
several studies have shown statistically significant evidence that etanercept, a tnf alpha inhibitor, can reduce symptoms present in post-stroke syndrome by targeting the excess tnf alpha produced in the csf. |
2023-04-17 |
2023-08-14 |
Not clear |
| Andrew M Joseph, Monica Karas, Cesar E Jara Silva, Melissa Leyva, Abdus Salam, Mehul Sinha, Yonathan Aliye Asfaw, Ayesha Fonseca, Steven Cordova, Marlon Reyes, Jonathan Quinonez, Samir Ruxmoha. The Potential Role of Etanercept in the Management of Post-stroke Pain: A Literature Review. Cureus. vol 15. issue 3. 2023-04-17. PMID:37065345. |
studies have also shown improvements in not only post-stroke pain but also in traumatic brain injury and dementia. further research is needed to explore the effects of tnf alpha on stroke prognosis and determine the optimal frequency and duration of etanercept treatment for post-stroke pain. |
2023-04-17 |
2023-08-14 |
Not clear |
| Xinping Tian, Mengtao Li, Nan Jiang, Yang Zhao, Jing Li, Yangzhong Zhou, Yahong Wang, Ying Wang, Taotao Li, Yunjiao Yang, Yanhong Wang, Peter A Merkel, Xiaofeng Zen. Comparative Efficacy of Secukinumab versus Tumor Necrosis Factor Inhibitors for the Treatment of Takayasu's Arteritis. Arthritis & rheumatology (Hoboken, N.J.). 2023-03-14. PMID:36916777. |
tumor necrosis factor (tnf) alpha and interleukin 17 (il-17) are thought to be involved in the pathogenesis of takayasu's arteritis (tak) and tnf inhibitors (tnfis) are recommended for the treatment of tak. |
2023-03-14 |
2023-08-14 |
Not clear |
| Ghida Mohamed Hassan, Reham Hassan Ebrahi. The myokine Decorin improves the cardiac function in a rat model of isoprenaline induced myocardial infarction. Canadian journal of physiology and pharmacology. 2023-03-14. PMID:36917819. |
cardiac hemodynamics, serum lactate dehydrogenase(ldh), creatinekinase-mb(ck-mb), oxidative stress markers, gene expression for myocardial transforming growth factor beta 1 (tgf-β1), interleukin 1 b (il1 b),tumor necrosis factor alpha (tnf), cardiac caspase3 immunohistochemical analysis were done. |
2023-03-14 |
2023-08-14 |
rat |
| Priyanka Misra, Rupali Kalsi, Sachit Anand Arora, Kumar Saurav Singh, Simoona Athar, Anchal Sain. Effect of Low-Level Laser Therapy on Early Wound Healing and Levels of Inflammatory Mediators in Gingival Crevicular Fluid Following Open Flap Debridement. Cureus. vol 15. issue 2. 2023-03-13. PMID:36909061. |
gcf inflammatory mediators tumor necrosis factor (tnf) alpha and matrix metalloproteinases (mmp-8) decrease, and osteoprotegerin (opg) levels increase in both the test group and control group from baseline to 3 months and 6 months. |
2023-03-13 |
2023-08-14 |
Not clear |
| Naser-Aldin Lashgari, Nazanin Momeni Roudsari, Maryam Shayan, Sadaf Eshraghi, Saeideh Momtaz, Tannaz Jamialahmadi, Amir Hossein Abdolghaffari, Amirhossein Sahebka. Spinal Muscular Atrophy Treatment: The MTOR Regulatory Intervention. Current medicinal chemistry. 2023-02-15. PMID:36788689. |
mtor: mammalian/mechanistic target of rapamycin; sma: spinal muscular atrophy; igf-1r: insulin-like growth factor type 1 receptor; foxo3a: forkhead box class o 3a; eif4ebp1: eukaryotic translation initiation factor 4e-binding protein 1; atrogin-1 (fbox32): atrophy gene-1 (f-box only protein 32); traf2: tnf receptor-associated factor 2; p38 (mapk14): p38 (mitogen-activated protein kinase 14); rras2: ras related 2; erk (mapk1): extracellular signal-regulated kinase 1/2 (mitogen-activated protein kinase 1); sbma: spinal and bulbar muscular atrophy; smn: survival motor neuron; akt: protein kinase b; mafbx/atrogin-1: muscle atrophy f-box; murf-1: muscle ring-finger protein-1; wt: wild-type; gc-klf15-bcaa: circadian glucocorticoid-krüppel-like factor 15-branched-chain amino acid; sbma: spinal and bulbar muscular atrophy; pgc1α: proliferator-activated receptor γ coactivator 1 alpha ctrp3: c1q/tnf-related protein 3; smn: survival motor neuron; vegf: vascular endothelial growth factor; pten: phosphatase and tensin homolog. |
2023-02-15 |
2023-08-14 |
Not clear |
| Zehra Kanlı, Hülya Cabadak, Banu Aydı. Potential antiproliferative and apoptotic effects of pilocarpine combined with TNF alpha in chronic myeloid leukemia cells. Naunyn-Schmiedeberg's archives of pharmacology. 2023-02-13. PMID:36781441. |
potential antiproliferative and apoptotic effects of pilocarpine combined with tnf alpha in chronic myeloid leukemia cells. |
2023-02-13 |
2023-08-14 |
Not clear |
| Syed Alishan Nasir, Ronak Patel, Steven Wojkiewicz, Robyn Scaten. Infliximab-Induced Non-specific Interstitial Pneumonitis in a Patient With Ulcerative Colitis (UC). Cureus. vol 14. issue 12. 2023-02-01. PMID:36721597. |
infliximab belongs to the family of tumor necrosis factor (tnf) alpha inhibitors and since its development, it has revolutionized treatment for both rheumatological diseases and inflammatory bowel disease (ibd). |
2023-02-01 |
2023-08-14 |
Not clear |
| Hong-Ying Chen, Peng-Fei Yao, Yan-Qi Han, Xu Xu, Jun Xu, Bi-Yan Pan, Dong-Sheng Ouyang, Tie-Jun Zhan. ["Component-target-efficacy" network analysis and experimental verification of Qingkailing Oral Preparation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 1. 2023-02-01. PMID:36725269. |
the major components in qkl oral prescription, including hyodeoxycholic acid, baicalin, chlorogenic acid, isochlorogenic acid c, epigoitrin, geniposide, cholic acid, isochlorogenic acid a, and γ-aminobutyric acid, may interfere with multiple biological processes related to inflammation, immune regulation, fever, and convulsion by acting on the key protein targets such as il-6, tnf, prostaglandin-endoperoxide synthase 2(ptgs2), arachidonate 5-lipoxygenase(alox5), vascular cell adhesion molecule 1(vcam1), nitric oxide synthase 2(nos2), prostaglandin e2 receptor ep2 subtype(ptger2), gamma-aminobutyric acid receptor subunit alpha(gabra), gamma-aminobutyric acid type b receptor subunit 1(gabbr1), and 4-aminobutyrate aminotransferase(abat). |
2023-02-01 |
2023-08-14 |
Not clear |
| Agnieszka Kloch, Ewa J Mierzejewska, Renata Welc-Falęciak, Anna Bajer, Aleksandra Biedrzyck. Cytokine gene polymorphism and parasite susceptibility in free-living rodents: Importance of non-coding variants. PloS one. vol 18. issue 1. 2023-01-24. PMID:36693052. |
we focused on three cytokines: tumour necrosis factor (tnf), lymphotoxin alpha (ltα), and interferon beta (ifnβ1). |
2023-01-24 |
2023-08-14 |
Not clear |
| Xiaofen Tan, Yifan Wen, Zhijun Han, Xuyang Su, Jing Peng, Feng Chen, Yadong Wang, Tianming Wang, Changzhong Wang, Kelong M. Cinnamaldehyde ameliorates dextran sulfate sodium-induced colitis in mice by modulating TLR4/NF-κB signaling pathway and NLRP3 inflammasome activation. Chemistry & biodiversity. 2023-01-18. PMID:36653304. |
seven intersection targets shared by cin and uc were obtained, and four hub targets, i.e., toll-like receptor 4 (tlr4), transcription factor p65 (nf-κb), nf-kappa-b inhibitor alpha (iκbα), prostaglandin g/h synthase 2 (cox2) were acquired, which were mainly involved in nf-κb, tumour necrosis factor (tnf), toll-like receptor and nod-like receptor signaling pathways. |
2023-01-18 |
2023-08-14 |
mouse |
| Amal Ben Othman, Ridha Ben Ali, Azaiez Ben Akacha, Michèle Véronique El Ma. Modulation of inflammatory mediators involved in the antinociceptive and anti-inflammatory effects of a new thioamide derivative: thiocyanoacetamide. Inflammopharmacology. 2023-01-13. PMID:36639425. |
the evaluation of inflammation mediators demonstrated that the pretreatment with thm induced the decrease in the amount of both il-1 beta and tnf alpha in plasma and the increase in their amount in the tissue of the injection site. |
2023-01-13 |
2023-08-14 |
rat |
| Hans K Ghayee, Yiling Xu, Heather Hatch, Richard Brockway, Asha S Multani, Tongjun Gu, Wendy B Bollag, Adina Turcu, William E Rainey, Juilee Rege, Kazutaka Nanba, Vikash J Bhagwandin, Fiemu Nwariaku, Victor Stastny, Adi F Gazdar, Jerry W Shay, Richard J Auchus, Sergei G Tevosia. Development of Human Adrenocortical Adenoma (HAA1) Cell Line from Zona Reticularis. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36614027. |
surprisingly, hdaci treatment induced broad activation of the tumor necrosis factor (tnf) alpha pathway. |
2023-01-08 |
2023-08-14 |
human |
| Yong-Fang Yang, Shan-Xin Peng, Kai-Yue Wang, Chong-Tian Zhu, Hua-Sheng Zhong, Feng-Yuan Ch. [Effect of Mailuo Shutong Pills in treatment of ischemic stroke based on network pharmacological analysis and experimental verification]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 23. 2023-01-06. PMID:36604893. |
the key targets included akt1, phosphatidylinositol 3-kinase catalytic subunit alpha(pik3 ca), phosphatidylinositol 3-kinase regulatory subunit 1(pik3 r1), and nuclear factor-κb p65 subunit(rela), which were mainly involved in pi3 k/akt, tumor necrosis factor(tnf), and nf-κb signaling pathways. |
2023-01-06 |
2023-08-14 |
mouse |