| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Khaled G Abdel-Wahhab, Rehab S Sayed, Doaa G El-Sahra, Laila K Hassan, Ghada M Elqattan, Fathia A Manna. Echinacea purpurea extract intervention for counteracting neurochemical and behavioral changes induced by bifenthrin. Metabolic brain disease. 2023-12-27. PMID:38150137. |
also, bif induced a significant increase caspas-3, tumor necrosis factor alpha (tnf), and interleukin-1beta (il-1ß) in both areas; dopamine and serotonin levels, and ach-ase activity were markedly decreased in both areas. |
2023-12-27 |
2023-12-29 |
rat |
| Georg Greiner, Nadine Witzeneder, Klara Klein, Simone Tangermann, Petra Kodajova, Eva Jaeger, Franz Ratzinger, Marlene C Gerner, Mohamad Jawhar, Sigrid Baumgartner, Karin Fruehwirth, Klaus G Schmetterer, Johannes Zuber, Karoline V Gleixner, Matthias Mayerhofer, Ilse Schwarzinger, Ingrid Simonitsch-Klupp, Harald Esterbauer, Constance Baer, Wencke Walter, Manja Meggendorfer, Robert Strassl, Torsten Haferlach, Karin Hartmann, Lukas Kenner, Wolfgang R Sperr, Andreas Reiter, Veronika Sexl, Michel Arock, Peter Valent, Gregor Hoerman. TNF alpha promotes clonal dominance of KIT D816V+ cells in mastocytosis: role of survivin and impact on prognosis. Blood. 2023-12-24. PMID:38142424. |
tnf alpha promotes clonal dominance of kit d816v+ cells in mastocytosis: role of survivin and impact on prognosis. |
2023-12-24 |
2023-12-27 |
human |
| Charu Goel, Nidhish Kumar, Anil K Tripathi, Sunita Tiwari, Ashutosh Shrivastava, Saurabh Shukla, Alok Mishra, Anshuman Srivastav. Plasma Levels of Organochlorine Pesticides and Tumor Necrosis Factor-Alpha: A Potential Risk Factor for Developing Acquired Aplastic Anemia in the North Indian Population. Cureus. vol 15. issue 9. 2023-10-30. PMID:37900403. |
there is a significant positive correlation of tnf alpha with ocps (alpha hch, lindane, delta hch, heptachlor, aldrin, p,p'- ddd, and methoxychlor pesticides). |
2023-10-30 |
2023-11-08 |
human |
| Vishal Devarkonda, Shravya Balmuri, Maria Antonia Costa Cruz Akabane, Hugo Akaban. Adalimumab-associated Philadelphia chromosome positive acute lymphoblastic leukaemia in a patient with Crohn's disease. BMJ case reports. vol 16. issue 10. 2023-10-25. PMID:37879713. |
the us food and drug administration has approved tnf(tumor necrosis factor) alpha inhibitors to manage a range of inflammatory conditions, including crohn's disease, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other inflammatory disorders. |
2023-10-25 |
2023-11-08 |
human |
| Vishal Devarkonda, Shravya Balmuri, Maria Antonia Costa Cruz Akabane, Hugo Akaban. Adalimumab-associated Philadelphia chromosome positive acute lymphoblastic leukaemia in a patient with Crohn's disease. BMJ case reports. vol 16. issue 10. 2023-10-25. PMID:37879713. |
however, these inhibitors can potentially increase the risk of secondary blood malignancies due to tnf alpha's role in various cellular processes such as angiogenesis, cell cycle proliferation, apoptosis and differentiation. |
2023-10-25 |
2023-11-08 |
human |
| Vishal Devarkonda, Shravya Balmuri, Maria Antonia Costa Cruz Akabane, Hugo Akaban. Adalimumab-associated Philadelphia chromosome positive acute lymphoblastic leukaemia in a patient with Crohn's disease. BMJ case reports. vol 16. issue 10. 2023-10-25. PMID:37879713. |
furthermore, we conducted a literature review on this subject and identified five similar cases of all associated with tnf alpha inhibitors. |
2023-10-25 |
2023-11-08 |
human |
| Shrivani Sriskanthadevan-Pirahas, Abdul Qadeer Tinwala, Michael J Turingan, Shahoon Khan, Savraj S Grewa. Mitochondrial metabolism in Drosophila macrophage-like cells regulates body growth via modulation of cytokine and insulin signaling. Biology open. 2023-10-18. PMID:37850733. |
we also find that tfam knockdown leads to decreased hemocyte jnk signaling and decreased expression of the tnf alpha homolog, eiger in hemocytes. |
2023-10-18 |
2023-11-08 |
drosophila_melanogaster |
| Corrine F Monaco, John S Davi. Mechanisms of angioregression of the corpus luteum. Frontiers in physiology. vol 14. 2023-10-16. PMID:37841308. |
microvascular endothelial cells are sensitive to released factors during luteolysis, including thrombospondin, endothelin, and cytokines like tumor necrosis factor alpha (tnf) and transforming growth factor β 1 (tgfb1). |
2023-10-16 |
2023-11-08 |
Not clear |
| Andrea Fracchia, Drirh Khare, Samar Da'na, Reuven Or, Amnon Buxboim, Boaz Nachmias, Claudine Barkatz, Regina Golan-Gerstl, Swasti Tiwari, Polina Stepensky, Yuval Nevo, Hadar Benyamini, Sharona Elgavish, Osnat Almogi-Hazan, Batia Avn. Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Apoptosis, TNF Alpha and Interferon Gamma Response Gene mRNA Expression in T Lymphocytes. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37761990. |
mesenchymal stromal cell-derived small extracellular vesicles modulate apoptosis, tnf alpha and interferon gamma response gene mrna expression in t lymphocytes. |
2023-09-28 |
2023-10-07 |
human |
| Quynh T Cao, Mira Ishak, Israel Shpilman, Jeremy A Hirot. TNF-α and Poly(I:C) induction of A20 and activation of NF-κB signaling are independent of ABCF1 in human airway epithelial cells. Scientific reports. vol 13. issue 1. 2023-09-07. PMID:37679460. |
we demonstrated that with abcf1 silencing under basal conditions, tnf alpha induced protein 3 (tnfaip3/a20) protein expression and downstream expression and activation of transcription factors, nf-κb and interferon regulatory factor 3 (irf-3), were not disrupted. |
2023-09-07 |
2023-10-07 |
human |
| Zhifang Tang, Hanzhen Feng, Xusheng Chen, Shuiyan Shao, Chuan L. SNORC knockdown alleviates inflammation, autophagy defect and matrix degradation of chondrocytes in osteoarthritis development. Molecular and cellular biochemistry. 2023-09-02. PMID:37659033. |
knocking down snorc in il-1β-induced chondrocytes obviously suppressed the production of nitric oxide (no), il-6, tumor necrosis factor (tnf)-α and prostaglandin e2 (pge2) to alleviate inflammation, and reduced the protein levels of a disintegrin and metalloproteinase with thrombospondin 5 (adamts5) and matrix metallopeptidase (mmp)13 and elevated collagen type 2 alpha 1 (col2a1) level to improve matrix degradation. |
2023-09-02 |
2023-09-07 |
rat |
| Fredrik N Albach, Gerd-Rüdiger Burmester, Johanna Muck. [Therapeutic antibodies in rheumatology]. Zeitschrift fur Rheumatologie. 2023-09-01. PMID:37656186. |
more than 100 years later, a new era in the treatment of rheumatic diseases began in 1998 with the approval of infliximab, an antibody directed against tumor necrosis factor alpha (tnf alpha). |
2023-09-01 |
2023-09-07 |
Not clear |
| Sinead Maguire, Anna Molt. Pregnancy & neonatal outcomes in spondyloarthritis. Best practice & research. Clinical rheumatology. 2023-08-31. PMID:37652852. |
factors associated with impaired fertility in spa include pain, fatigue, stiffness, functional disorders, depression, anxiety, negative body image, and the use of nonsteroidal anti-inflammatory drugs (nsaids) preconceptionally, while tnf alpha inhibitors may play a role in improving fertility in certain cases. |
2023-08-31 |
2023-09-07 |
Not clear |
| Yashaswini Kelagere, Kaitlin K Scholand, Erica N DeJong, Andrea I Boyd, Zhiyuan Yu, Roger A Astley, Michelle C Callegan, Dawn Me Bowdish, Helen P Makarenkova, Cintia S de Paiv. TNF is a critical cytokine in age-related dry eye disease. The ocular surface. 2023-08-27. PMID:37634571. |
our results show the increased protein and mrna levels of tnf in aged lacrimal glands, accompanied by increased tnf, il1β, il-18, ccl5, cxcl1, il-2, il-2 receptor alpha (cd25), ifn-γ, il-12p40, il-17, and il-10 proteins in tears of aged mice. |
2023-08-27 |
2023-09-07 |
mouse |
| Mădălina Moldovan, Ana-Maria Păpurică, Mara Muntean, Raluca Maria Bungărdean, Dan Gheban, Bianca Moldovan, Gabriel Katona, Luminița David, Gabriela Adriana Fili. Effects of Gold Nanoparticles Phytoreduced with Rutin in an Early Rat Model of Diabetic Retinopathy and Cataracts. Metabolites. vol 13. issue 8. 2023-08-25. PMID:37623898. |
oxidative stress (mda, cat, sod) was assessed in serum and eye homogenates, and inflammatory cytokines (il-1 beta, il-6, tnf alpha) were quantified in ocular tissues. |
2023-08-25 |
2023-09-07 |
rat |
| Lan-Tu-Ya Wu, Zhu-Hui Qiao, Jia-Bin Tian, Jia-Lin Lin, Su-Chun Hou, Xiao-Ming Li. The effect of secukinumab treatment for psoriasis on serum cytokines and correlation with disease severity. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). vol 29. issue 7. 2023-07-31. PMID:37522491. |
to investigate the effects of secukinumab treatment for psoriasis on different functional cytokines and inflammatory mediators in patients' serum methods: enzyme-linked immunosorbent assay was used to detect interleukin (il)-1β and il-1ra associated with intrinsic immunity; il-6, il-18, and growth regulated oncogene alpha (groα) associated with neutrophils; il-12, tumour necrosis factor (tnf)-α, and interferon (ifn)-γ associated with th1; il-23, il-17a, and il-22 associated with th17; thymus activation regulated chemokine (tarc), il-13, and defensin beta 2 (defb2) associated with th2; vascular endothelial growth factor (vegf)-a and il-10 associated with angiogenesis; and ifn-γ associated with sepsis in the peripheral blood of 12 patients with common psoriasis treated with secukinumab and 15 healthy controls. |
2023-07-31 |
2023-08-14 |
Not clear |
| A Nemmar, S Beegam, N E Zaaba, O Elzaki, A Pathan, B H Al. Waterpipe smoke inhalation induces lung injury and aortic endothelial dysfunction in mice. Physiological research. vol 72. issue 3. 2023-07-14. PMID:37449747. |
inhalation of wps induced an increase in the number of macrophages and neutrophils and the concentrations of protein, tumor necrosis factor alpha (tnf alpha), interleukin (il)-1beta, and glutathione in bronchoalveolar lavage fluid. |
2023-07-14 |
2023-08-14 |
mouse |
| Frangky Sangande, Kurnia Agustini, Krisyanti Budipraman. Antihyperlipidemic mechanisms of a formula containing Curcuma xanthorrhiza, Sechium edule, and Syzigium polyanthum: In silico and in vitro studies. Computational biology and chemistry. vol 105. 2023-07-01. PMID:37392529. |
based on the topology parameters, we identified 6 significant targets that play an important role in reducing lipid serum levels: hmg-coa reductase (hmgcr), peroxisome proliferator-activated receptor alpha (ppara), rac-alpha serine/threonine-protein kinase (akt1), epidermal growth factor receptor (egfr), matrix metalloproteinase-9 (mmp9), and tumor necrosis factor-alpha (tnf). |
2023-07-01 |
2023-08-14 |
Not clear |
| Thibault Leger, Aurelien Brun, Kassandra Lanchais, Jean-Paul Rigaudière, Arnaud Briat, Yann Guitton, Fabien Marchand, Anne Tournadre, Frederic Cape. Docosahexaenoic acid and etanercept could reduce functional and metabolic alterations during collagen-induced arthritis in rats without any synergistic effect. Life sciences. 2023-06-03. PMID:37270172. |
independently, pharmacological agents targeting key molecular regulators of the pathology such as tnf alpha could be proposed, but multiple therapies are frequently necessary increasing the risk for toxicity and adverse effects. |
2023-06-03 |
2023-08-14 |
rat |
| Didik Priyandoko, Wahyu Widowati, Hanna Sari Widya Kusuma, Ervi Afifah, Cahyaning Riski Wijayanti, Rizal Rizal, Ika Adhani Sholihah, Galuh Wening Permatasari, Anggia Ramadhani, Didik Huswo Utom. Inflammation inhibitory activity of green tea, soybean, and guava extracts during Sars-Cov-2 infection through TNF protein in cytokine storm. Computational biology and chemistry. vol 105. 2023-05-29. PMID:37247574. |
sars-cov-2 severity is determined by a cytokine storm condition, in which the innate immune system creates an unregulated and excessive production of pro-inflammatory such il-1, il-6, nf kappa b, and tnf alpha signaling molecules known as cytokines. |
2023-05-29 |
2023-08-14 |
Not clear |