| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lijiang Wang, Supaporn Kulthinee, Nahiro Yano, Huai Wen, Ling X Zhang, Zachary S S L Saleeba, Na Jin, Ou Chen, Ting C Zha. Gold nanoparticles-conjugation of irisin enhances therapeutic effect by improving cardiac function and attenuating inflammation in sepsis. Molecular diversity. 2024-07-18. PMID:39026117. |
enzyme linked immunosorbent assay (elisa) was conducted to examine release of interleukin 6 (il6) and the tumor necrosis factor (tnf) alpha. |
2024-07-18 |
2024-07-21 |
mouse |
| Georgios Zouris, Dimitrios Stergios Evangelopoulos, Ioannis S Benetos, John Vlami. The Use of TNF-α Inhibitors in Active Ankylosing Spondylitis Treatment. Cureus. vol 16. issue 6. 2024-07-02. PMID:38952586. |
a search was performed in the pubmed database using the following keywords: ("tnf alpha inhibitors" or "anti tnf-a" or "tnf-a inhibitors" or "anti tnf-alpha" or "etanercept " or "golimumab" or "infliximab" or "certolizumab pegol" or "adalimumab") and "ankylosing spondylitis". |
2024-07-02 |
2024-07-04 |
Not clear |
| Kajal Gaba, Parveen Malhotra, Anil Kumar, Pooja Suneja, Amita Suneja Dan. Understanding the Genetic Basis of Celiac Disease: A Comprehensive Review. Cell biochemistry and biophysics. 2024-06-22. PMID:38907939. |
however, present study indicate that most current research predominantly focus on cytokines, specifically the tnf alpha gene. |
2024-06-22 |
2024-06-25 |
Not clear |
| Murillo Duarte-Silva, Rogério Serafim Parra, Marley Ribeiro Feitosa, Viviani Nardini, Sandra Regina Maruyama, José Joaquim Ribeiro da Rocha, Omar Feres, Cristina Ribeiro de Barros Cardos. Leukocyte dysfunction and reduced CTLA-4 expression are associated with perianal Crohn's disease. Clinical and experimental immunology. vol 217. issue 1. 2024-06-20. PMID:38517030. |
however, their pbmc was characterized by decreased il-6 production, while patients with a history of pcd produced higher il-6, il-8, and interferon-γ, along with decreased tumor necrosis factor alpha (tnf). |
2024-06-20 |
2024-06-22 |
human |
| Lisa Kongrat, Arash Maleki, Ploysai Rujkorakarn, Michael J Margolis, Tate Valerio, Yasmin Massoudi, Stephen D Anesi, C Stephen Foste. Outcomes of Intravenous Tocilizumab Treatment for Refractory Pars Planitis. Ocular immunology and inflammation. 2024-05-23. PMID:38781578. |
to evaluate outcomes of intravenous (iv) tocilizumab (tcz) in patients with pars planitis refractory to conventional immunomodulatory therapy and anti-tumor necrosis factor (tnf) alpha agents. |
2024-05-23 |
2024-05-27 |
Not clear |
| Piotr K Krajewski, Łukasz Matusiak, Sascha Ständer, Diamant Thaçi, Jacek C Szepietowski, Henner Zirpe. Risk of cardiovascular disorders in hidradenitis suppurativa patients: a large-scale, propensity-matched global retrospective cohort study. International journal of dermatology. 2024-04-21. PMID:38644522. |
the creation of atherosclerotic plaque is characterized by endothelial dysfunction driven by elevated concentrations of interleukin (il)-1, il-6, and il-18 among others, as well as tumor necrosis factor (tnf) alpha. |
2024-04-21 |
2024-04-24 |
Not clear |
| Laura L Mateu-Arrom, Lluis L Pui. Choosing the right biologic treatment for moderate-to-severe plaque psoriasis: the impact of comorbidities. Expert review of clinical pharmacology. 2024-04-11. PMID:38603464. |
currently, there is a wide range of biological treatments available for moderate to severe psoriasis, including tumor necrosis alpha (tnf) inhibitors, il12/23 inhibitor, il17 inhibitors, and il23 inhibitors. |
2024-04-11 |
2024-04-14 |
Not clear |
| Molly Klimak, Farshid Guila. Genetically engineered macrophages derived from iPSCs for self-regulating delivery of anti-inflammatory biologic drugs. Journal of tissue engineering and regenerative medicine. vol 2024. 2024-04-04. PMID:38571695. |
to develop a macrophage-based therapy to treat chronic inflammation, we engineered a novel induced pluripotent stem cell (ipsc)-derived macrophage capable of delivering soluble tnf receptor 1 (tnfr1), an anti-inflammatory biologic inhibitor of tumor necrosis factor alpha (tnf-α), in an auto-regulated manner in response to tnf-α. |
2024-04-04 |
2024-04-06 |
Not clear |
| Samir Ali Abd El-Kaream, Nabila Gaber Ali Hussein, Sohier Mahmoud El-Kholey, Ahmed Mohammed Abd Elmoez Ibrahim Elhelbaw. Microneedle combined with iontophoresis and electroporation for assisted transdermal delivery of goniothalamus macrophyllus for enhancement sonophotodynamic activated cancer therapy. Scientific reports. vol 14. issue 1. 2024-04-04. PMID:38575628. |
in addition significantly increased apoptotic genes expressions (p53, caspase (3, 9), bax, and tnf alpha) and on the other hand decreased anti- apoptotic (bcl-2) and angiogenic (vegf) genes expressions. |
2024-04-04 |
2024-04-07 |
mouse |
| Yiyi Hu, Yunchuan Li, Haodan Zhu, Dandan Wang, Junming Zhou, Yanxiu Ni, Rongli Guo, Baochao Fan, Bin L. In vitro suppression of porcine epidemic diarrhea virus by Panax notoginseng saponins: assessing antiviral potential. Archives of virology. vol 169. issue 5. 2024-04-02. PMID:38565720. |
pns exerts its anti-pedv activity specifically at the genome replication stage, and mrna-seq analysis demonstrated that treatment with pns resulted in increased expression of various genes, including ifit1 (interferon-induced protein with tetratricopeptide repeats 1), ifit3 (interferon-induced protein with tetratricopeptide repeats 3), cfh (complement factor h), igsf10 (immunoglobulin superfamily member 10), id2 (inhibitor of dna binding 2), spp1 (secreted phosphoprotein 1), plcb4 (phospholipase c beta 4), and fabp4 (fatty acid binding protein 4), but it resulted in decreased expression of il1a (interleukin 1 alpha), tnfrsf19 (tnf receptor superfamily member 19), cdh8 (cadherin 8), ddit3 (dna damage inducible transcript 3), gadd45a (growth arrest and dna damage inducible alpha), ptprg (protein tyrosine phosphatase receptor type g), pck2 (phosphoenolpyruvate carboxykinase 2), and adgra2 (adhesion g protein-coupled receptor a2). |
2024-04-02 |
2024-04-05 |
Not clear |
| Amanda S Pellowe, Michelle J Wu, Tae-Yun Kang, Tracy D Chung, Adrian Ledesma-Mendoza, Erica Herzog, Andre Levchenko, Ian Odell, John Varga, Anjelica L Gonzale. TGFβ1 Drives Integrin Dependent Pericyte Migration and Microvascular Destabilization In Fibrotic Disease. The American journal of pathology. 2024-03-28. PMID:38548268. |
using pro-inflammatory tnf alpha (tnfα) or fibrotic growth factor tgf beta-1 (tgfβ1), human pc inflammatory and fibrotic phenotypes were evaluated by assessing their migration, matrix deposition, integrin expression, and subsequent effects on endothelial dysfunction. |
2024-03-28 |
2024-03-31 |
human |
| Kristina Boss, Jodi Hagen, Megan Constans, Christine Goetz, Alexander E Kalyuzhn. Comparing Flow Cytometry and ELISpot for Detection of IL-10, IL-6, and TNF Alpha on Human PBMCs. Methods in molecular biology (Clifton, N.J.). vol 2768. 2024-03-19. PMID:38502389. |
comparing flow cytometry and elispot for detection of il-10, il-6, and tnf alpha on human pbmcs. |
2024-03-19 |
2024-03-23 |
human |
| Moni Roy, Himanshu Rathore, Ashish K Ro. Pulmonary Embolism in a Patient with Rheumatoid Arthritis on Etanercept Therapy. Journal of community hospital internal medicine perspectives. vol 14. issue 1. 2024-03-14. PMID:38482093. |
etanercept is a tnf alpha and beta receptor blocker. |
2024-03-14 |
2024-03-16 |
Not clear |
| M L E Andersson, M Zimmerman, E Brogren, S Bergman, L Strindberg, E Fryk, P A Jansso. Baseline levels of circulating galectin-1 associated with radiographic hand but not radiographic knee osteoarthritis at a two-year follow-up. Osteoarthritis and cartilage open. vol 6. issue 2. 2024-03-12. PMID:38469554. |
we tested the potential of circulating galectin-1, interleukin (il)-1 beta, il-6, and tumour necrosis factor alpha (tnf alpha) levels at baseline in individuals with knee pain as biomarkers for development of radiographic knee and/or hand osteoarthritis (oa). |
2024-03-12 |
2024-03-14 |
Not clear |
| Fatima Zahra El Rhaoussi, Zineb Boukhal, Fouad Haddad, Mohamed Tahiri, Wafaa Hliwa, Ahmed Bellabah, Badre Wafa. Erythromelalgia Secondary to Anti-Tumor Necrosis Factor (TNF) Alpha Therapy: A Report of Two Cases. Cureus. vol 16. issue 2. 2024-03-12. PMID:38469019. |
erythromelalgia secondary to anti-tumor necrosis factor (tnf) alpha therapy: a report of two cases. |
2024-03-12 |
2024-03-14 |
Not clear |
| Fatima Zahra El Rhaoussi, Zineb Boukhal, Fouad Haddad, Mohamed Tahiri, Wafaa Hliwa, Ahmed Bellabah, Badre Wafa. Erythromelalgia Secondary to Anti-Tumor Necrosis Factor (TNF) Alpha Therapy: A Report of Two Cases. Cureus. vol 16. issue 2. 2024-03-12. PMID:38469019. |
due to a strong suspicion of erythromelalgia secondary to tumor necrosis factor (tnf) alpha inhibitor therapy, infliximab was replaced with ustekinumab. |
2024-03-12 |
2024-03-14 |
Not clear |
| Ridha Azimudin, Sinduja Palati, Priyadharshini . Evaluating Tumor Necrosis Factor (TNF)-Alpha Pro-inflammatory Cytokines in Healthy and Oral Squamous Cell Carcinoma Patients With and Without Diabetes. Cureus. vol 16. issue 1. 2024-02-26. PMID:38406163. |
considering the impact of tnf alpha in both disease progression, it is an interesting biological marker to explore. |
2024-02-26 |
2024-02-28 |
human |
| Renu Heir, Zahra Abbasi, Pragya Komal, Haider F Altimimi, Marie Franquin, Dionysia Moschou, Julien Chambon, David Stellwage. Astrocytes are the source of TNF mediating homeostatic synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-02-23. PMID:38395613. |
tumor necrosis factor alpha (tnf) mediates homeostatic synaptic plasticity (hsp) in response to chronic activity blockade, and prior work has established that it is released from glia. |
2024-02-23 |
2024-02-26 |
mouse |
| Selma Bouden, Lilia Laadhar, Jihene Soua, Meriam Ben Messaoud, Leila Rouached, Imene Ayadi, Olfa Saidane, Aicha Ben Tekaya, Ines Mahmoud, Sonia Rekik, Héla Sahli Srairi, Rawdha Tekaya, Syrine Bellakhal, Monia Fekih, Leila Abdelmoula, Maryem Kalle. No Correlation between Anti-drug Antibodies and Therapeutic Response in Tunisian Patients with Chronic Inflammatory Diseases Treated by TNF Blockers. Current rheumatology reviews. 2024-02-05. PMID:38314598. |
tumor necrosis factor alpha (tnf alpha) blockers such as infliximab (ifx) and adalimumab (ada) had significantly changed the course of inflammatory diseases such as rheumatoid arthritis (ra), spondyloarthritis (spa) and crohn's disease (cd). |
2024-02-05 |
2024-02-07 |
Not clear |
| Tomoyuki Sato, Katsutaka Oish. Time-restricted feeding has a limited effect on hepatic lipid accumulation, inflammation and fibrosis in a choline-deficient high-fat diet-induced murine NASH model. PloS one. vol 19. issue 1. 2024-01-29. PMID:38285666. |
although gene expression of tnf alpha in the liver was suppressed by trf, it did not exhibit a suppressive effect on hepatic lipid accumulation, gene expression of cytokines and macrophage markers (mcp1, il1b, f4/80), or fibrosis, as evaluated by sirius red staining and western blot analysis of alpha-smooth muscle actin. |
2024-01-29 |
2024-02-01 |
Not clear |