| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng-Mu Hu, Qi Cao, Xiong-Wen Lv, Wen-Ming Cheng, Rong Li, Jun L. Protective effects of total flavonoids from Litsea coreana on alcoholic fatty liver in rats associated with down-regulation adipose differentiation-related protein expression. The American journal of Chinese medicine. vol 40. issue 3. 2012-10-23. PMID:22745073. |
serum levels of tg, tc, ldl-c, hdl-c, tnf-α, insulin, and glucose were measured, histopathologic changes were determined, and expression of adipose differentiation-related protein (adrp) in the liver were evaluated by western blotting and immunohistochemistry, respectively. |
2012-10-23 |
2023-08-12 |
rat |
| Cheng-Mu Hu, Qi Cao, Xiong-Wen Lv, Wen-Ming Cheng, Rong Li, Jun L. Protective effects of total flavonoids from Litsea coreana on alcoholic fatty liver in rats associated with down-regulation adipose differentiation-related protein expression. The American journal of Chinese medicine. vol 40. issue 3. 2012-10-23. PMID:22745073. |
the results showed that treatment with tflc resulted in decreased serum levels of tg, tc, ldl-c, tnf-α, glucose and insulin, as well as improved liver index. |
2012-10-23 |
2023-08-12 |
rat |
| Martin R Salazar, Horacio A Carbajal, Walter G Espeche, Carlos E Leiva Sisnieguez, Eduardo Balbín, Carlos A Dulbecco, Marcelo Aizpurúa, Alberto G Marillet, Gerald M Reave. Relation among the plasma triglyceride/high-density lipoprotein cholesterol concentration ratio, insulin resistance, and associated cardio-metabolic risk factors in men and women. The American journal of cardiology. vol 109. issue 12. 2012-10-18. PMID:22449634. |
using tg/hdl concentration ratios >2.5 in women and >3.5 in men identified subgroups of men and women that were comparable in terms of insulin resistance and associated cardiometabolic risk, with significantly higher values for fasting plasma insulin, homeostasis model assessment of insulin resistance, blood pressure, body mass index, waist circumference, and glucose and tg concentrations and lower hdl cholesterol concentrations than in women and men below these cut points. |
2012-10-18 |
2023-08-12 |
human |
| Hemantkumar Somabhai Chaudhari, Uma Bhandari, Geetika Khann. Preventive effect of embelin from embelia ribes on lipid metabolism and oxidative stress in high-fat diet-induced obesity in rats. Planta medica. vol 78. issue 7. 2012-10-11. PMID:22450777. |
a range of parameters were tested including body weight gain, body mass index (bmi), blood pressure, visceral fat pad weights, serum levels of glucose, insulin, leptin, apolipoprotein b (apob), total cholesterol (tc), triglycerides (tg), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), hepatic thiobarbituric acid-reactive substances (tbars), superoxide dismutase (sod), catalase (cat), and glutathione (gsh). |
2012-10-11 |
2023-08-12 |
rat |
| Per B Jeppesen, Stig E Dyrskog, Andreas Agger, Soren Gregersen, Michele Colombo, Jianzhong Xiao, Kjeld Hermanse. Can stevioside in combination with a soy-based dietary supplement be a new useful treatment of type 2 diabetes? An in vivo study in the diabetic goto-kakizaki rat. The review of diabetic studies : RDS. vol 3. issue 4. 2012-10-02. PMID:17487343. |
compared to normal chow diet, stevioside in combination with spi shows the following beneficial effects in gk rats with mild type 2 diabetes: 1. a 56% reduction in plasma glucose (p < 0.001), 2. a 118% increase in first-phase insulin (p < 0.005), 3. a 20% reduction in glucagons (p < 0.05), 4. a 28% reduction in total cholesterol (p < 0.001), 5. a 13% reduction in ffa (p < 0.01), 6. a 49% reduction in tg (p < 0.001) and 7. a 11% reduction in the systolic blood pressure (p < 0.001). |
2012-10-02 |
2023-08-12 |
rat |
| Mingqing Huang, Youliang Xie, Lidian Chen, Kedan Chu, Shuisheng Wu, Jinjian Lu, Xiuping Chen, Yitao Wang, Xiaoping La. Antidiabetic effect of the total polyphenolic acids fraction from Salvia miltiorrhiza Bunge in diabetic rats. Phytotherapy research : PTR. vol 26. issue 6. 2012-10-02. PMID:22095927. |
the results showed that paf induced a significant decrease in fasting blood glucose (fbg), fasting blood insulin (fins), total cholesterol (tc), triglyceride (tg) and blood urea nitrogen (bun), and an obvious increase in insulin sensitivity index (isi) in diabetic rats induced by a high fat diet and a low dose of streptozocin (stz). |
2012-10-02 |
2023-08-12 |
rat |
| A Cools, D Maes, J Buyse, I D Kalmar, J-A Vandermeiren, G P J Janssen. Effect of N,N-dimethylglycine supplementation in parturition feed for sows on metabolism, nutrient digestibility and reproductive performance. Animal : an international journal of animal bioscience. vol 4. issue 12. 2012-10-02. PMID:22445374. |
the plasma was analyzed for insulin, glucose, fructosamine, leptin, thiobarbituric acid reactive substances (tbars), ferric reducing ability of plasma (frap), non-esterified fatty acids (nefa) and triglycerides (tg) and an oral glucose tolerance test was performed. |
2012-10-02 |
2023-08-12 |
Not clear |
| Ranabir Salam, Achouba Singh Kshetrimayum, Reetu Keisa. Testosterone and metabolic syndrome: The link. Indian journal of endocrinology and metabolism. vol 16 Suppl 1. 2012-10-02. PMID:22701831. |
metabolic syndrome (mets) or "syndrome x" which is a constellation of insulin resistance, hyperglycemia, hypertension, low high-density lipoprotein cholesterol (hdl-c), and increased very-low-density lipoprotein (vldl) and triglyceride (tg) levels. |
2012-10-02 |
2023-08-12 |
human |
| Min Dong, Zhi-Cheng Gong, Xing-Ping Dai, Guang-Hua Lei, Hong-Bin Lu, Lan Fan, Jian Qu, Hong-Hao Zhou, Zhao-Qian Li. Serine racemase rs391300 G/A polymorphism influences the therapeutic efficacy of metformin in Chinese patients with diabetes mellitus type 2. Clinical and experimental pharmacology & physiology. vol 38. issue 12. 2012-09-28. PMID:21933224. |
serum fasting plasma glucose (fpg), postprandial plasma glucose (ppg), glycated haemoglobin (hba1c), fasting serum insulin (fins), postprandial serum insulin (pins), triglycerol (tg), cholesterol (cho), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), homeostasis model assessment for insulin resistance (homa-ir), and body mass index (bmi) were determined before and after metformin treatment. |
2012-09-28 |
2023-08-12 |
human |
| Young Sik Cho, Chi Hyun Kim, Ki Young Kim, Hyae Gyeong Cheo. Protective effects of arachidonic acid against palmitic acid-mediated lipotoxicity in HIT-T15 cells. Molecular and cellular biochemistry. vol 364. issue 1-2. 2012-09-20. PMID:22203421. |
in parallel with its protective effects against pa-induced lipotoxicity, aa restored impaired insulin expression and secretion induced by pa. aa but not etya increased intracellular triglyceride (tg) in the presence of pa compared with pa alone, and xanthohumol, a diacylglycerol acyltransferase (dgat) inhibitor, reversed aa-induced protection from pa. taken together, our results suggest that aa protects against pa-induced lipotoxicity in clonal hit-t15 pancreatic β cells, and the protective effects may be associated with tg accumulation, possibly through sequestration of lipotoxic pa into tg. |
2012-09-20 |
2023-08-12 |
Not clear |
| Lei Liu, Zhigang Song, Ardashir Sheikhahmadi, Hongchao Jiao, Hai Li. Effect of corticosterone on gene expression of feed intake regulatory peptides in laying hens. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 162. issue 4. 2012-09-20. PMID:22554475. |
treatment of hens with cort stimulated an increase (p<0.05) in plasma cort, glucose, uric acid (ua), insulin, cholesterol (chol) and triiodothyronine (t(3)), but the concentrations of plasma non-esterified fatty acids (nefa) and triacylglycerol (tg) were decreased (p<0.05). |
2012-09-20 |
2023-08-12 |
Not clear |
| Lixin Ma, Rukhsana Gul, Javad Habibi, Ming Yang, Lakshmi Pulakat, Adam Whaley-Connell, Carlos M Ferrario, James R Sower. Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the transgenic (mRen2) rat. American journal of physiology. Heart and circulatory physiology. vol 302. issue 11. 2012-09-12. PMID:22447938. |
we used the transgenic (tg) (mren2)27 rat, which overexpresses the murine renin transgene and manifests insulin resistance and left ventricular dysfunction. |
2012-09-12 |
2023-08-12 |
rat |
| Shashaank Vattikuti, Juen Guo, Carson C Cho. Heritability and genetic correlations explained by common SNPs for metabolic syndrome traits. PLoS genetics. vol 8. issue 3. 2012-09-04. PMID:22479213. |
mets traits included body-mass index (bmi), waist-to-hip ratio (whr), systolic blood pressure (sbp), fasting glucose (glu), fasting insulin (ins), fasting trigylcerides (tg), and fasting high-density lipoprotein (hdl). |
2012-09-04 |
2023-08-12 |
Not clear |
| Amir Elokely, Amira Shoukry, Tarek A Ghonemy, Mrwan Atia, Ghada Am. Association of adiponectin with cardiovascular events in diabetic and non-diabetic hemodialysis patients. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. vol 23. issue 4. 2012-08-30. PMID:22805386. |
all subjects were subjected to complete clinical examination, including determination of mean arterial blood pressure (mabp), body mass index (bmi), waist to hip ratio, routine laboratory investigations, fasting plasma glucose, fasting plasma insulin, lipid profile (cholesterol, tg, ldl, hdl), determination of insulin resistance by homeostasis model assessment index (homa-ir) and estimation of serum levels of adiponectin. |
2012-08-30 |
2023-08-12 |
human |
| Amir Elokely, Amira Shoukry, Tarek A Ghonemy, Mrwan Atia, Ghada Am. Association of adiponectin with cardiovascular events in diabetic and non-diabetic hemodialysis patients. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. vol 23. issue 4. 2012-08-30. PMID:22805386. |
serum adiponectin has a significant positive correlation with hdl and a significant negative correlation with mabp, bmi, plasma insulin, homa-ir, ldl, tg and cholesterol in all the patients. |
2012-08-30 |
2023-08-12 |
human |
| N Schweighofer, E Lerchbaum, O Trummer, V Schwetz, S Pilz, T R Pieber, B Obermayer-Pietsc. Androgen levels and metabolic parameters are associated with a genetic variant of F13A1 in women with polycystic ovary syndrome. Gene. vol 504. issue 1. 2012-08-28. PMID:22565190. |
in pcos women, f13a1 gene variants were significantly associated with body mass index (bmi) (p=0.013), systolic blood pressure (p=0.042), insulin response (aucins) (p=0.015), triglycerides (tg) (p=0.001), and high density lipoprotein cholesterol (hdl) (p=0.012). |
2012-08-28 |
2023-08-12 |
Not clear |
| Yuqing Huo, Xin Guo, Honggui Li, Hang Xu, Vera Halim, Weiyu Zhang, Huan Wang, Yang-Yi Fan, Kuok Teong Ong, Shih-Lung Woo, Robert S Chapkin, Douglas G Mashek, Yanming Chen, Hui Dong, Fuer Lu, Lai Wei, Chaodong W. Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses. The Journal of biological chemistry. vol 287. issue 25. 2012-08-24. PMID:22556414. |
using ap2-pfkfb3 transgenic (tg) mice, we explored the ability of targeted adipocyte pfkfb3/ipfk2 overexpression to modulate diet-induced inflammatory responses and insulin resistance arising from fat deposition in both adipose and liver tissues. |
2012-08-24 |
2023-08-12 |
mouse |
| Yuqing Huo, Xin Guo, Honggui Li, Hang Xu, Vera Halim, Weiyu Zhang, Huan Wang, Yang-Yi Fan, Kuok Teong Ong, Shih-Lung Woo, Robert S Chapkin, Douglas G Mashek, Yanming Chen, Hui Dong, Fuer Lu, Lai Wei, Chaodong W. Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses. The Journal of biological chemistry. vol 287. issue 25. 2012-08-24. PMID:22556414. |
compared with wild-type littermates (controls) on a high fat diet (hfd), tg mice exhibited increased adiposity, decreased adipose inflammatory response, and improved insulin sensitivity. |
2012-08-24 |
2023-08-12 |
mouse |
| Yuqing Huo, Xin Guo, Honggui Li, Hang Xu, Vera Halim, Weiyu Zhang, Huan Wang, Yang-Yi Fan, Kuok Teong Ong, Shih-Lung Woo, Robert S Chapkin, Douglas G Mashek, Yanming Chen, Hui Dong, Fuer Lu, Lai Wei, Chaodong W. Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses. The Journal of biological chemistry. vol 287. issue 25. 2012-08-24. PMID:22556414. |
in a parallel pattern, hfd-fed tg mice showed increased hepatic steatosis, decreased liver inflammatory response, and improved liver insulin sensitivity compared with controls. |
2012-08-24 |
2023-08-12 |
mouse |
| Sahar Mazloomi, Faranak Sharifi, Reza Hajihosseini, Sadroddin Kalantari, Saideh Mazloomzade. Association between Hypoadiponectinemia and Low Serum Concentrations of Calcium and Vitamin D in Women with Polycystic Ovary Syndrome. ISRN endocrinology. vol 2012. 2012-08-23. PMID:22363895. |
the concentrations of calcium, 25-oh-vitamin d (25ohd), adiponectin, insulin, glucose, total cholesterol, hdl-cholesterol, triglyceride (tg), and androgens were measured in fasting blood samples. |
2012-08-23 |
2023-08-12 |
human |