| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haiyan Zhang, Wen-Jun Shen, Yuan Cortez, Fredric B Kraemer, Salman Azha. Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways. American journal of physiology. Gastrointestinal and liver physiology. vol 304. issue 1. 2013-02-20. PMID:23104557. |
feeding ob/ob mice a chow diet supplemented with either low (0.83 g/kg diet) or high-dose (2.5 g/kg diet) ndga for 16 wk significantly improved plasma triglyceride (tg), inflammatory chemokine levels, hyperinsulinemia, insulin sensitivity, and glucose intolerance. |
2013-02-20 |
2023-08-12 |
mouse |
| Ramdas B Pandhare, B Sangameswaran, Popat B Mohite, Shantaram G Khanag. Antidiabetic Activity of Aqueous Leaves Extract of Sesbania sesban (L) Merr. in Streptozotocin Induced Diabetic Rats. Avicenna journal of medical biotechnology. vol 3. issue 1. 2013-02-15. PMID:23407749. |
the fasting blood glucose levels (bgl), serum insulin level and biochemical data such as glycosylated hemoglobin, total cholesterol (tc), triglycerides (tg), high density lipoproteins (hdl) and low density lipoproteins (ldl) were evaluated and all were compared to that of the known anti-diabetic drug glibenclamide (0.25 mg/kg b.w.). |
2013-02-15 |
2023-08-12 |
rat |
| Shinobu Shimizu, Tetsuya Hosooka, Tomokazu Matsuda, Shun-ichiro Asahara, Maki Koyanagi-Kimura, Ayumi Kanno, Alberto Bartolome, Hiroaki Etoh, Megumi Fuchita, Kyoko Teruyama, Hiroaki Takahashi, Hiroyuki Inoue, Yusuke Mieda, Naoko Hashimoto, Susumu Seino, Yoshiaki Kid. DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice. Journal of molecular endocrinology. vol 49. issue 2. 2013-02-12. PMID:22822047. |
vildagliptin ameliorated hyperglycemia in tg mice by increasing the serum concentration of insulin and decreasing the serum concentration of glucagon. |
2013-02-12 |
2023-08-12 |
mouse |
| Clinton R Bruce, Steve Risis, Joanne R Babb, Christine Yang, Greg M Kowalski, Ahrathy Selathurai, Robert S Lee-Young, Jacquelyn M Weir, Kazuaki Yoshioka, Yoh Takuwa, Peter J Meikle, Stuart M Pitson, Mark A Febbrai. Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet-fed mice. Diabetes. vol 61. issue 12. 2013-01-25. PMID:22961081. |
accordingly, skeletal muscle and whole-body insulin sensitivity were improved in sphk1 tg, compared with wt mice, when fed an hfd. |
2013-01-25 |
2023-08-12 |
mouse |
| James F Nelson, Randy Strong, Alex Bokov, Vivian Diaz, Walter War. Probing the relationship between insulin sensitivity and longevity using genetically modified mice. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 67. issue 12. 2013-01-24. PMID:23089336. |
mice with increased insulin sensitivity either had a null mutation of protein tyrosine phosphatase 1b (ptp-1b(-/-)) or overexpressed peroxisome proliferator-activated receptor-α coactivator (pgc)-1α (pgc-1α(tg)). |
2013-01-24 |
2023-08-12 |
mouse |
| James F Nelson, Randy Strong, Alex Bokov, Vivian Diaz, Walter War. Probing the relationship between insulin sensitivity and longevity using genetically modified mice. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 67. issue 12. 2013-01-24. PMID:23089336. |
life spans of mice with increased insulin sensitivity were shortened overall (ptp-1b(-/-) mice) or partially (pgc-1α(tg): survival at the 25th percentile was reduced). |
2013-01-24 |
2023-08-12 |
mouse |
| Debasis De, Kazi Monjur Ali, Kausik Chatterjee, Tushar Kanti Bera, Debidas Ghos. Antihyperglycemic and antihyperlipidemic effects of n-hexane fraction from the hydro-methanolic extract of sepals of Salmalia malabarica in streptozotocin-induced diabetic rats. Journal of complementary & integrative medicine. vol 9. 2013-01-22. PMID:22732718. |
the effect of the fraction on fasting blood glucose (fbg), serum insulin, hemoglobin, glycated hemoglobin, total cholesterol (tc), triglyceride (tg), high density lipoprotein cholesterol (hdlc), low density lipoprotein cholesterol (ldlc), very low density lipoprotein cholesterol (vldlc), phospholipids, free fatty acids, urea, uric acid, creatinine, albumin and transaminases were investigated in stz-induced diabetic rat. |
2013-01-22 |
2023-08-12 |
rat |
| Swee Keong Yeap, Norlaily Mohd Ali, Hamidah Mohd Yusof, Noorjahan Banu Alitheen, Boon Kee Beh, Wan Yong Ho, Soo Peng Koh, Kamariah Lon. Antihyperglycemic effects of fermented and nonfermented mung bean extracts on alloxan-induced-diabetic mice. Journal of biomedicine & biotechnology. vol 2012. 2013-01-16. PMID:23091343. |
the serum levels of cholesterol, triglyceride (tg), and low-density lipoprotein (ldl) were also lowered while insulin secretion and antioxidant level as measured by malonaldehyde (mda) assays were significantly improved in the plasma of the fermented mung bean-treated group in alloxan-induced hyperglycemic mouse. |
2013-01-16 |
2023-08-12 |
mouse |
| Wanhua Xu, Rong Li, Suhua Zhang, Lilin Gong, Zhihong Wang, Wei Ren, Chenxi Xia, Qifu L. The relationship between high-sensitivity C-reactive protein and ApoB, ApoB/ApoA1 ratio in general population of China. Endocrine. vol 42. issue 1. 2012-12-13. PMID:22246850. |
from the lowest to the highest quartile of hscrp, the values for bmi, wc, bp, homa-ir, insulin, glucose level, triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), apob and the apob/apolipoprotein a1 (apoa1) ratio were increased as the hscrp level increased (p < 0.01), and high-density lipoprotein cholesterol (hdl-c) and apoa1 levels declined as hscrp level increased (p < 0.0001). |
2012-12-13 |
2023-08-12 |
human |
| Jong-Seok Kim, Hee-Taik Kang, Jae-Yong Shim, Hye-Ree Le. The association between the triglyceride to high-density lipoprotein cholesterol ratio with insulin resistance (HOMA-IR) in the general Korean population: based on the National Health and Nutrition Examination Survey in 2007-2009. Diabetes research and clinical practice. vol 97. issue 1. 2012-12-04. PMID:22607906. |
this study explores the association between the ratio of triglyceride (tg) and high-density lipoprotein cholesterol (hdl-c) and insulin resistance according to waist circumference in the general korean population. |
2012-12-04 |
2023-08-12 |
Not clear |
| Su-Jin Kim, Cuilan Nian, Subashini Karunakaran, Susanne M Clee, Carlos M Isales, Christopher H S McIntos. GIP-overexpressing mice demonstrate reduced diet-induced obesity and steatosis, and improved glucose homeostasis. PloS one. vol 7. issue 7. 2012-12-03. PMID:22802954. |
in contrast, although gip tg mice demonstrated enhanced β-cell function, resulting in improved glucose tolerance and insulin sensitivity, they exhibited reduced diet-induced obesity. |
2012-12-03 |
2023-08-12 |
mouse |
| Masaru Ochiai, Tatsuhiro Matsu. Increased stearoyl-CoA desaturase index and triglyceride content in the liver of rats after a single bout of swimming exercise. Bioscience, biotechnology, and biochemistry. vol 76. issue 7. 2012-11-26. PMID:22785489. |
a single bout of endurance exercise increased the hepatic tg content and scd index which might be effective in protecting against insulin resistance. |
2012-11-26 |
2023-08-12 |
rat |
| Matthew T Flowers, Lacmbouh Ade, Maggie S Strable, James M Ntamb. Combined deletion of SCD1 from adipose tissue and liver does not protect mice from obesity. Journal of lipid research. vol 53. issue 8. 2012-11-23. PMID:22669918. |
adipose scd1 deletion had no effect on glucose or insulin tolerance or on hepatic triglyceride (tg) accumulation. |
2012-11-23 |
2023-08-12 |
mouse |
| Ariel D Quiroga, Richard Lehne. Liver triacylglycerol lipases. Biochimica et biophysica acta. vol 1821. issue 5. 2012-11-13. PMID:21963564. |
the hallmark of obesity and one of the key contributing factors to insulin resistance, type 2 diabetes and cardiovascular disease is excess triacylglycerol (tg) storage. |
2012-11-13 |
2023-08-12 |
Not clear |
| J-P Bastard, M-E Lavoie, V Messier, D Prud'homme, R Rabasa-Lhore. Evaluation of two new surrogate indices including parameters not using insulin to assess insulin sensitivity/resistance in non-diabetic postmenopausal women: a MONET group study. Diabetes & metabolism. vol 38. issue 3. 2012-11-05. PMID:22405724. |
the study evaluated and compared, with other surrogate indices of insulin sensitivity/resistance (is/r), the relevance of the tyg index, a product of fasting glucose and triglyceride (tg) levels, and the egir index, which includes tg, high-density lipoprotein cholesterol (hdl-c) and waist circumference in its formula to estimate is/r, in non-diabetic postmenopausal women. |
2012-11-05 |
2023-08-12 |
Not clear |
| Mehmet Mustafa Can, Esra Can, Olcay Ozveren, Ertugrul Okuyan, Burak Ayca, Mustafa Hakan Dincka. Epicardial fat tissue thickness in preeclamptic and normal pregnancies. ISRN obstetrics and gynecology. vol 2012. 2012-11-05. PMID:23119176. |
total cholesterol, high-density lipoprotein cholesterol (hdl), and triglyceride levels (tg) and low-density-lipoprotein cholesterol (ldl), and homeostatic model assessment of insulin resistance (homa-ir) levels were assessed. |
2012-11-05 |
2023-08-12 |
human |
| Samad Akbarzadeh, Soghra Ghasemi, Mohamadreza Kalantarhormozi, Iraj Nabipour, Fateme Abbasi, Alnaz Aminfar, Seyed Mojtaba Jaffari, Niloofar Motamed, Ali Movahed, Mostafa Mirzaei, Ali Reza Rahba. Relationship among plasma adipokines, insulin and androgens level as well as biochemical glycemic and lipidemic markers with incidence of PCOS in women with normal BMI. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 28. issue 7. 2012-10-29. PMID:22309615. |
the fasting plasma glucose (fpg), triglyceride (tg), chol, and high-density lipoprotein cholesterol (hdl-c), insulin, testosterone, omentin and vaspin were measured by the enzymatic methods. |
2012-10-29 |
2023-08-12 |
human |
| Samad Akbarzadeh, Soghra Ghasemi, Mohamadreza Kalantarhormozi, Iraj Nabipour, Fateme Abbasi, Alnaz Aminfar, Seyed Mojtaba Jaffari, Niloofar Motamed, Ali Movahed, Mostafa Mirzaei, Ali Reza Rahba. Relationship among plasma adipokines, insulin and androgens level as well as biochemical glycemic and lipidemic markers with incidence of PCOS in women with normal BMI. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 28. issue 7. 2012-10-29. PMID:22309615. |
the results from this study show a significant increase in the amount of insulin, testosterone, homeostasis model assessments for insulin resistance, tg and lower hdl in the patient group. |
2012-10-29 |
2023-08-12 |
human |
| Hiromu Ohnogi, Shoko Hayami, Yoko Kudo, Suzu Deguchi, Shigetoshi Mizutani, Tatsuji Enoki, Yuko Tanimura, Wataru Aoi, Yuji Naito, Ikunoshin Kato, Toshikazu Yoshikaw. Angelica keiskei extract improves insulin resistance and hypertriglyceridemia in rats fed a high-fructose drink. Bioscience, biotechnology, and biochemistry. vol 76. issue 5. 2012-10-26. PMID:22738961. |
fructose significantly increased the levels of serum insulin and triglyceride (tg) compared with the control level. |
2012-10-26 |
2023-08-12 |
rat |
| Hiromu Ohnogi, Shoko Hayami, Yoko Kudo, Suzu Deguchi, Shigetoshi Mizutani, Tatsuji Enoki, Yuko Tanimura, Wataru Aoi, Yuji Naito, Ikunoshin Kato, Toshikazu Yoshikaw. Angelica keiskei extract improves insulin resistance and hypertriglyceridemia in rats fed a high-fructose drink. Bioscience, biotechnology, and biochemistry. vol 76. issue 5. 2012-10-26. PMID:22738961. |
treatment with an ethanol extract of a. keiskei (ae) significantly reduced the levels of blood glucose (-16.5%), serum insulin (-47.3%), homa-r (-56.4%) and tg (-24.2%). |
2012-10-26 |
2023-08-12 |
rat |