| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi-ming Ma, Rong-ya Tao, Qian Liu, Juan Li, Jin-ying Tian, Xiao-lin Zhang, Zhi-yan Xiao, Fei Y. PTP1B inhibitor improves both insulin resistance and lipid abnormalities in vivo and in vitro. Molecular and cellular biochemistry. vol 357. issue 1-2. 2012-02-24. PMID:21603884. |
in irm mice, the insulin resistance was improved; the body weight and the levels of tc and tg were also reduced by oral ccf06240 administration. |
2012-02-24 |
2023-08-12 |
mouse |
| Ranganath Muniyappa, Vandana Sachdev, Stanislav Sidenko, Madia Ricks, Darleen C Castillo, Amber B Courville, Anne E Sumne. Postprandial endothelial function does not differ in women by race: an insulin resistance paradox? American journal of physiology. Endocrinology and metabolism. vol 302. issue 2. 2012-02-16. PMID:22045315. |
although african-american women were less insulin-sensitive [insulin sensitivity index (mean ± sd): 3.6 ± 1.5 vs. 5.2 ± 2.6, p = 0.02], both fasting triglyceride (tg: 56 ± 37 vs. 97 ± 49 mg/dl, p = 0.007) and incremental tg area under the curve (auc(0-6hr): 279 ± 190 vs. 492 ± 255 mg·dl(-1)·min(-1)·10(-2), p = 0.008) were lower in african-american than white women. |
2012-02-16 |
2023-08-12 |
Not clear |
| Martha Guevara-Cruz, Armando R Tovar, Carlos A Aguilar-Salinas, Isabel Medina-Vera, Lidia Gil-Zenteno, Isaac Hernández-Viveros, Patricia López-Romero, Guillermo Ordaz-Nava, Samuel Canizales-Quinteros, Luz E Guillen Pineda, Nimbe Torre. A dietary pattern including nopal, chia seed, soy protein, and oat reduces serum triglycerides and glucose intolerance in patients with metabolic syndrome. The Journal of nutrition. vol 142. issue 1. 2012-02-13. PMID:22090467. |
all participants had decreases in body weight (bw), bmi, and waist circumference during the 2-mo treatment (p < 0.0001); however, only the dp group had decreases in serum tg, c-reactive protein (crp), and auc for insulin and gi after a glucose tolerance test. |
2012-02-13 |
2023-08-12 |
human |
| Samir Ben Ali, Riadh Jemaa, Bouchra Ftouhi, Amani Kallel, Moncef Feki, Hedia Slimene, Naziha Kaabach. Relationship of plasma leptin and adiponectin concentrations with menopausal status in Tunisian women. Cytokine. vol 56. issue 2. 2012-01-30. PMID:21802312. |
fasting glucose, hdl-cholesterol (hdl-c), triglycerides (tg), total cholesterol (tc), insulin, leptin, and adiponectin concentrations were measured. |
2012-01-30 |
2023-08-12 |
human |
| Samir Ben Ali, Riadh Jemaa, Bouchra Ftouhi, Amani Kallel, Moncef Feki, Hedia Slimene, Naziha Kaabach. Relationship of plasma leptin and adiponectin concentrations with menopausal status in Tunisian women. Cytokine. vol 56. issue 2. 2012-01-30. PMID:21802312. |
menopause had no effect on the mean values of bmi, insulin or homa-ir, hdl-c, and tg. |
2012-01-30 |
2023-08-12 |
human |
| Fei-Feng Sheng, Xing-Ping Dai, Jian Qu, Guang-Hua Lei, Hong-Bin Lu, Jing Wu, Xiao-Jing Xu, Qi Pei, Min Dong, Ying-Zi Liu, Hong-Hao Zhou, Zhao-Qian Li. NAMPT -3186C/T polymorphism affects repaglinide response in Chinese patients with Type 2 diabetes mellitus. Clinical and experimental pharmacology & physiology. vol 38. issue 8. 2012-01-26. PMID:21631570. |
serum fasting plasma glucose (fpg), post-prandial plasma glucose (ppg), glycated haemoglobin (hbalc), fasting serum insulin (fins), post-prandial serum insulin (pins), triglyceride (tg), total cholesterol (cho), homeostasis model assessment of insulin resistance (homa-ir), low-density lipoprotein-cholesterol (ldl-c) and high-density lipoprotein-cholesterol (hdl-c) were determined before and after repaglinide treatment. |
2012-01-26 |
2023-08-12 |
Not clear |
| E A Teeple, S Teich, D P Schuster, M P Michalsk. Early metabolic improvement following bariatric surgery in morbidly obese adolescents. Pediatric blood & cancer. vol 58. issue 1. 2012-01-12. PMID:22021118. |
comparative analysis demonstrated significant improvement in weight, bmi, insulin, hba1c, c-peptide, %b, %s, ir, cholesterol, percentile cholesterol, tg, percentile tg, hdl, percentile hdl, ldl, percentile ldl, and vldl. |
2012-01-12 |
2023-08-12 |
Not clear |
| Fahim Abbasi, Gerald M Reave. Comparison of two methods using plasma triglyceride concentration as a surrogate estimate of insulin action in nondiabetic subjects: triglycerides × glucose versus triglyceride/high-density lipoprotein cholesterol. Metabolism: clinical and experimental. vol 60. issue 12. 2012-01-10. PMID:21632070. |
the objective was to compare relationships between insulin-mediated glucose uptake and surrogate estimates of insulin action, particularly those using fasting triglyceride (tg) and high-density lipoprotein cholesterol (hdl-c) concentrations. |
2012-01-10 |
2023-08-12 |
human |
| Fahim Abbasi, Gerald M Reave. Comparison of two methods using plasma triglyceride concentration as a surrogate estimate of insulin action in nondiabetic subjects: triglycerides × glucose versus triglyceride/high-density lipoprotein cholesterol. Metabolism: clinical and experimental. vol 60. issue 12. 2012-01-10. PMID:21632070. |
fasting tg, hdl-c, glucose, and insulin concentrations were measured; and calculations were made of the following: (1) plasma concentration ratio of tg/hdl-c, (2) tg × fasting glucose (tyg index), (3) homeostasis model assessment of insulin resistance, and (4) insulin area under the curve (insulin-auc) during a glucose tolerance test. |
2012-01-10 |
2023-08-12 |
human |
| Fahim Abbasi, Gerald M Reave. Comparison of two methods using plasma triglyceride concentration as a surrogate estimate of insulin action in nondiabetic subjects: triglycerides × glucose versus triglyceride/high-density lipoprotein cholesterol. Metabolism: clinical and experimental. vol 60. issue 12. 2012-01-10. PMID:21632070. |
insulin-auc correlated most closely with sspg (r ∼ 0.75, p < .001), with lesser but comparable correlations between sspg and tg/hdl-c ratio, tyg index, homeostasis model assessment of insulin resistance, and fasting tg and insulin (r ∼ 0.60, p < .001). |
2012-01-10 |
2023-08-12 |
human |
| Camila Manrique, Guido Lastra, Javad Habibi, Lakshmi Pulakat, Rebecca Schneider, William Durante, Roger Tilmon, Jenna Rehmer, Melvin R Hayden, Carlos M Ferrario, Adam Whaley-Connell, James R Sower. Nebivolol improves insulin sensitivity in the TGR(Ren2)27 rat. Metabolism: clinical and experimental. vol 60. issue 12. 2012-01-10. PMID:21640361. |
we sought to determine the impact of nebivolol, a selective vasodilatory β₁-adrenergic blocker, on whole-body insulin sensitivity, skeletal muscle oxidative stress, insulin signaling, and glucose transport in the transgenic tg(mren2)27 rat (ren2). |
2012-01-10 |
2023-08-12 |
rat |
| Kevin C Maki, Andrea L Lawless, Kathleen M Kelley, Mary R Dicklin, Arianne L Schild, Tia M Rain. Prescription omega-3-acid ethyl esters reduce fasting and postprandial triglycerides and modestly reduce pancreatic β-cell response in subjects with primary hypertriglyceridemia. Prostaglandins, leukotrienes, and essential fatty acids. vol 85. issue 3-4. 2011-12-27. PMID:21775113. |
this double-blind, randomized, controlled crossover trial in 19 men and women with hypertriglyceridemia (fasting tg ≥150 and ≤499mg/dl) examined lipid responses and indices of insulin sensitivity and secretion following a liquid meal tolerance test. |
2011-12-27 |
2023-08-12 |
human |
| Kevin C Maki, Andrea L Lawless, Kathleen M Kelley, Mary R Dicklin, Arianne L Schild, Tia M Rain. Prescription omega-3-acid ethyl esters reduce fasting and postprandial triglycerides and modestly reduce pancreatic β-cell response in subjects with primary hypertriglyceridemia. Prostaglandins, leukotrienes, and essential fatty acids. vol 85. issue 3-4. 2011-12-27. PMID:21775113. |
six weeks treatment with pom3 vs. corn oil resulted in significant lower mean fasting (-50.1mg/dl, p<0.001) and postprandial tg (-76.1mg/dl, p<0.001), higher mean fasting glucose (2.8mg/dl, p=0.062), reduced mean disposition index (2.1 vs. 2.4, p=0.037), and no change in the median matsuda composite insulin sensitivity index (3.3 vs. 3.2, p=0.959). |
2011-12-27 |
2023-08-12 |
human |
| Alessandra Ghio, Alessandra Bertolotto, Veronica Resi, Laura Volpe, Graziano Di Ciann. Triglyceride metabolism in pregnancy. Advances in clinical chemistry. vol 55. 2011-12-22. PMID:22126027. |
from the 12th week of gestation, phospholipids, cholesterol (total, ldl, hdl), and triglycerides (tg) increase in response to estrogen stimulation and insulin resistance. |
2011-12-22 |
2023-08-12 |
Not clear |
| Tomoki Nagare, Hiroshi Sakaue, Michihiro Matsumoto, Yongheng Cao, Kenjiro Inagaki, Mashito Sakai, Yasuhiro Takashima, Kyoko Nakamura, Toshiyuki Mori, Yuko Okada, Yasushi Matsuki, Eijiro Watanabe, Kazutaka Ikeda, Ryo Taguchi, Naomi Kamimura, Shigeo Ohta, Ryuji Hiramatsu, Masato Kasug. Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion. The Journal of biological chemistry. vol 286. issue 43. 2011-12-15. PMID:21862590. |
the ap2-klf15 tg mice manifest insulin resistance and are resistant to the development of obesity induced by maintenance on a high fat diet. |
2011-12-15 |
2023-08-12 |
mouse |
| Tomoki Nagare, Hiroshi Sakaue, Michihiro Matsumoto, Yongheng Cao, Kenjiro Inagaki, Mashito Sakai, Yasuhiro Takashima, Kyoko Nakamura, Toshiyuki Mori, Yuko Okada, Yasushi Matsuki, Eijiro Watanabe, Kazutaka Ikeda, Ryo Taguchi, Naomi Kamimura, Shigeo Ohta, Ryuji Hiramatsu, Masato Kasug. Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion. The Journal of biological chemistry. vol 286. issue 43. 2011-12-15. PMID:21862590. |
this is supported by the findings that restoration of scd1 expression in white adipose tissue of ap2-klf15 tg mice exhibited increased oxidative stress in white adipose tissue and reduced insulin secretion with hyperglycemia. |
2011-12-15 |
2023-08-12 |
mouse |
| Mark G Shrime, Scott R Bauer, Anna C McDonald, Nubaha H Chowdhury, Cordelia E M Coltart, Eric L Din. Flavonoid-rich cocoa consumption affects multiple cardiovascular risk factors in a meta-analysis of short-term studies. The Journal of nutrition. vol 141. issue 11. 2011-12-12. PMID:21956956. |
data were collected for: blood pressure, pulse, total cholesterol, hdl cholesterol, ldl cholesterol, tg, bmi, c-reactive protein, flow-mediated vascular dilation (fmd), fasting glucose, fasting insulin, serum isoprostane, and insulin sensitivity/resistance indices. |
2011-12-12 |
2023-08-12 |
human |
| Robert K McNamara, Ronald Jandacek, Therese Rider, Patrick Tso, Allyson Cole-Strauss, Jack W Lipto. Atypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: relationship with stearoyl-CoA desaturase activity. Schizophrenia research. vol 129. issue 1. 2011-12-06. PMID:21474290. |
recent preclinical and clinical evidence suggests that the stearoyl-coa desaturase-1 (scd1) enzyme plays a key role in the regulation of triglyceride (tg) biosynthesis and insulin sensitivity, and in vitro studies have found that antipsychotic medications up-regulate scd1 mrna expression. |
2011-12-06 |
2023-08-12 |
rat |
| Robert K McNamara, Ronald Jandacek, Therese Rider, Patrick Tso, Allyson Cole-Strauss, Jack W Lipto. Atypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: relationship with stearoyl-CoA desaturase activity. Schizophrenia research. vol 129. issue 1. 2011-12-06. PMID:21474290. |
effects on liver scd1 mrna expression and an index of scd1 activity (the plasma 18:1/18:0 ratio, 'desaturation index') were determined, as were postprandial plasma triglyceride (tg), glucose, insulin, and polyunsaturated fatty acid (pufa) levels. |
2011-12-06 |
2023-08-12 |
rat |
| Yan-Yan Chen, Yung-Seng Lee, Jin-Ping Wang, Ya-Yun Jiang, Hui Li, Ya-Li An, Ying-Hua Hu, Kok O Lee, Guang-Wei L. Longitudinal study of childhood adiposity and the risk of developing components of metabolic syndrome-the Da Qing children cohort study. Pediatric research. vol 70. issue 3. 2011-12-06. PMID:21629155. |
birth weight, television (tv) viewing time at 5 y old, blood pressure, anthropometric measurements, fasting plasma insulin (fi), and triglycerides (tg) levels were measured at 5 and 10 y old. |
2011-12-06 |
2023-08-12 |
Not clear |