| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R W Schwize. Effects of dissociation and culture on the maintenance of insulin, glucagon and somatostatin release by neonatal rat islets of Langerhans. Life sciences. vol 35. issue 7. 1984-10-02. PMID:6147743. |
effects of dissociation and culture on the maintenance of insulin, glucagon and somatostatin release by neonatal rat islets of langerhans. |
1984-10-02 |
2023-08-12 |
rat |
| R W Schwize. Effects of dissociation and culture on the maintenance of insulin, glucagon and somatostatin release by neonatal rat islets of Langerhans. Life sciences. vol 35. issue 7. 1984-10-02. PMID:6147743. |
as estimated by the radioimmunoassay of insulin, glucagon and somatostatin in tissue extracts, the amount of islet tissue available for culture was reduced 50-70% following dissociation; an additional loss occurred after the first day in vitro. |
1984-10-02 |
2023-08-12 |
rat |
| R W Schwize. Effects of dissociation and culture on the maintenance of insulin, glucagon and somatostatin release by neonatal rat islets of Langerhans. Life sciences. vol 35. issue 7. 1984-10-02. PMID:6147743. |
the concentrations of insulin and glucagon in the medium approximately doubled and somatostatin increased 3-fold. |
1984-10-02 |
2023-08-12 |
rat |
| V E Eysselei. [Neurotensin--what is known about its role as a hormone in the gastrointestinal tract?]. Klinische Wochenschrift. vol 62. issue 11. 1984-10-01. PMID:6471777. |
potential actions of neurotensin include thermoregulation, regulation of hormone release from brain (pituitary hormones) and gut (glucagon, insulin, somatostatin, pancreatic polypeptide), increase of vascular permeability, vasodilatation, inhibition of gastric acid secretion, stimulation of pancreatic secretion and changes of gut motility from the fasting to the fed type. |
1984-10-01 |
2023-08-12 |
human |
| P O Schwille, W Engelhardt, E Gumbert, C Gebhardt, F P Gal. Long-term pancreatic duct occlusion impairs the entero-insular axis in the dog--failure of plasma VIP to respond as "incretin". Peptides. vol 5. issue 2. 1984-09-24. PMID:6147819. |
the two studies with glucose administration designed to demonstrate the release of insulin, vip, somatostatin into plasma as modified by enteric signals (represented by the difference of plasma peptide concentration during ogt minus peptide concentration during iv glucose) revealed the following: (1) basal plasma glucose, insulin, vip, somatostatin did not differ between sham and occ dogs; (2) after ogt in occ dogs the plasma glucose was elevated, whereas plasma insulin was markedly reduced, and vip, somatostatin were largely unchanged; (3) the integrated output of insulin only was impaired when considering the so-called entero-insulin axis, while integrated vip, somatostatin were unaltered. |
1984-09-24 |
2023-08-12 |
dog |
| P O Schwille, W Engelhardt, E Gumbert, C Gebhardt, F P Gal. Long-term pancreatic duct occlusion impairs the entero-insular axis in the dog--failure of plasma VIP to respond as "incretin". Peptides. vol 5. issue 2. 1984-09-24. PMID:6147819. |
it was concluded (a) the occ procedure in the dog has the capacity to subtotal destruction of the pancreatic acinar tissue, and of the entero-insular axis of insulin, the latter through yet unknown pathways, (b) the occ technique may be a useful tool for investigation of the nature of "incretin," (c) vip and somatostatin do not respond to elevated blood glucose and may have no role in the "incretin" concept of enteric modulation of the b-cell. |
1984-09-24 |
2023-08-12 |
dog |
| N Y Ip, C Baldwin, R E Zigmon. Acute stimulation of ganglionic tyrosine hydroxylase activity by secretin, VIP and PHI. Peptides. vol 5. issue 2. 1984-09-24. PMID:6147816. |
secretin and vasoactive intestinal peptide (vip) both increased th activity, whereas angiotensin ii, bombesin, bradykinin, cholecystokinin octapeptide, insulin, luteinizing hormone-releasing hormone, [d-ala2, met5]enkephalinamide, motilin, neurotensin, somatostatin, and substance p produced no effects. |
1984-09-24 |
2023-08-12 |
human |
| D Gonzalez-Barcena, F Mendoza, R Medina, D H Coy, W A Murphy, A V Schall. Effect of Ala-2-D-Trp-8-D-Cys-14-somatostatin on the arginine induced release of insulin, GH and glucagon in normal men. Endocrine research. vol 10. issue 1. 1984-09-19. PMID:6146518. |
somatostatin suppressed the release of insulin, glucagon and gh when administered in a dose of 100 micrograms/hr. |
1984-09-19 |
2023-08-12 |
human |
| D Gonzalez-Barcena, F Mendoza, R Medina, D H Coy, W A Murphy, A V Schall. Effect of Ala-2-D-Trp-8-D-Cys-14-somatostatin on the arginine induced release of insulin, GH and glucagon in normal men. Endocrine research. vol 10. issue 1. 1984-09-19. PMID:6146518. |
these results indicate that in humans this analog is a less potent inhibitor of insulin release than somatostatin. |
1984-09-19 |
2023-08-12 |
human |
| V Lance, J W Hamilton, J B Rouse, J R Kimmel, H G Polloc. Isolation and characterization of reptilian insulin, glucagon, and pancreatic polypeptide: complete amino acid sequence of alligator (Alligator mississippiensis) insulin and pancreatic polypeptide. General and comparative endocrinology. vol 55. issue 1. 1984-09-17. PMID:6146554. |
the insulin, glucagon, pancreatic polypeptide, and somatostatin contents of acid-alcohol extracts of alligator pancreas have been estimated by heterologous radioimmunoassay, and the insulin, glucagon, and pancreatic polypeptide have been isolated. |
1984-09-17 |
2023-08-12 |
chicken |
| M D Ruggere, Y C Pate. Somatostatin, glucagon, and insulin secretion from perfused pancreas of BB rats. The American journal of physiology. vol 247. issue 2 Pt 1. 1984-09-14. PMID:6147095. |
somatostatin, glucagon, and insulin secretion from perfused pancreas of bb rats. |
1984-09-14 |
2023-08-12 |
rat |
| M D Ruggere, Y C Pate. Somatostatin, glucagon, and insulin secretion from perfused pancreas of BB rats. The American journal of physiology. vol 247. issue 2 Pt 1. 1984-09-14. PMID:6147095. |
we reported previously that pancreatic somatostatin and glucagon content and d and a cells are reduced in spontaneously diabetic bb rats while portal plasma levels of these hormones are elevated but normalized by insulin therapy. |
1984-09-14 |
2023-08-12 |
rat |
| M D Ruggere, Y C Pate. Somatostatin, glucagon, and insulin secretion from perfused pancreas of BB rats. The American journal of physiology. vol 247. issue 2 Pt 1. 1984-09-14. PMID:6147095. |
a theophylline-induced paradoxical inhibition of somatostatin secretion that was normalized by insulin was found in insulin-openic diabetic rats. |
1984-09-14 |
2023-08-12 |
rat |
| D L McNeill, J E Brinn, D J Fletche. An immunocytochemical study of the pancreatic islet system of the channel catfish. The Anatomical record. vol 209. issue 3. 1984-09-12. PMID:6380340. |
islets were immunocytochemically stained using antisera to anglerfish insulin, porcine glucagon, and synthetic somatostatin and volume densities were quantified on light micrographs by point-counting procedures. |
1984-09-12 |
2023-08-12 |
Not clear |
| A Pernet, M Walker, G V Gill, H Orskov, K G Alberti, D G Johnsto. Metabolic effects of adrenaline and noradrenaline in man: studies with somatostatin. Diabete & metabolisme. vol 10. issue 2. 1984-09-11. PMID:6146542. |
somatostatin suppressed insulin, glucagon and growth hormone secretion and both magnified and prolonged the hyperglycaemic effect of adrenaline (maximal at 105 min, 11.3 +/- 0.5 mmol/l, p less than 0.01 versus adrenaline alone). |
1984-09-11 |
2023-08-12 |
Not clear |
| M W Roy, K C Lee, M S Jones, R E Mille. Neural control of pancreatic insulin and somatostatin secretion. Endocrinology. vol 115. issue 2. 1984-09-05. PMID:6146513. |
neural control of pancreatic insulin and somatostatin secretion. |
1984-09-05 |
2023-08-12 |
Not clear |
| M W Roy, K C Lee, M S Jones, R E Mille. Neural control of pancreatic insulin and somatostatin secretion. Endocrinology. vol 115. issue 2. 1984-09-05. PMID:6146513. |
second, the receptor mechanisms by which sympathetic nerve stimulation alters the secretion rates of somatostatin and insulin were assessed. |
1984-09-05 |
2023-08-12 |
Not clear |
| O Björkman, P Felig, J Wahre. Role of basal glucagon levels in the regulation of splanchnic glucose output and ketogenesis in insulin-deficient humans. Clinical physiology (Oxford, England). vol 4. issue 3. 1984-08-31. PMID:6146427. |
somatostatin infusion resulted in a 50% reduction in both insulin and glucagon concentrations and a transient decline in sgo which returned to baseline values by 86 +/- 11 min at which point the glucose infusion was no longer necessary to maintain euglycemia. |
1984-08-31 |
2023-08-12 |
human |
| O Björkman, P Felig, J Wahre. Role of basal glucagon levels in the regulation of splanchnic glucose output and ketogenesis in insulin-deficient humans. Clinical physiology (Oxford, England). vol 4. issue 3. 1984-08-31. PMID:6146427. |
somatostatin administration suppressed the arterial glucagon and insulin concentrations to values comparable to those observed during the infusion in the overnight fasted state. |
1984-08-31 |
2023-08-12 |
human |
| V P Fedotov, N V Sadovnikova, V I Gudoshnikov, L A Batrameeva, L V Aleshin. [Effect of C-terminal tetrapeptide cholecystokinin (CCK-4) on the function of the islands of Langerhans and the adenohypophysis]. Biulleten' eksperimental'noi biologii i meditsiny. vol 97. issue 6. 1984-08-24. PMID:6146360. |
it is concluded that cck-4 stimulates insulin, glucagon and somatostatin secretion by direct contact with target cells. |
1984-08-24 |
2023-08-12 |
rat |