| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F B Loud, J J Holst, E Egense, B Petersen, J Christianse. Is somatostatin a humoral regulator of the endocrine pancreas and gastric acid secretion in man? Gut. vol 26. issue 5. 1985-07-12. PMID:2860053. |
the effect of low dose infusions of somatostatin on meal stimulated gastric acid secretion was studied in eight healthy volunteers by intragastric titration after a peptone test meal with radioimmunoassay control of the plasma concentrations of somatostatin and the pancreatic hormones glucagon and insulin. |
1985-07-12 |
2023-08-11 |
human |
| I Lundquist, B Ahrén, R Håkanson, F Sundle. Quinacrine accumulation in pancreatic islet cells of rat and mouse: relationship to functional activity and effects on basal and stimulated insulin secretion. Diabetologia. vol 28. issue 3. 1985-07-11. PMID:3888758. |
the fluorescent acridine derivative, quinacrine, was found to accumulate in rat and mouse pancreatic islet cells storing insulin, glucagon, pancreatic polypeptide, or somatostatin. |
1985-07-11 |
2023-08-11 |
mouse |
| K Hermanse. Forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. Endocrinology. vol 116. issue 6. 1985-07-10. PMID:2581771. |
forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. |
1985-07-10 |
2023-08-11 |
dog |
| K Hermanse. Forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. Endocrinology. vol 116. issue 6. 1985-07-10. PMID:2581771. |
the effects of forskolin on the release of somatostatin, glucagon, and insulin were studied using the isolated, perfused dog pancreas. |
1985-07-10 |
2023-08-11 |
dog |
| K Hermanse. Forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. Endocrinology. vol 116. issue 6. 1985-07-10. PMID:2581771. |
it was found that concentrations ranging from 0.075 microm-1 microm stimulated the secretion of somatostatin, glucagon, and insulin in a dose-related manner. |
1985-07-10 |
2023-08-11 |
dog |
| P Molinero, J R Calvo, R Goberna, J M Guerrer. The interaction of vasoactive intestinal peptide (VIP) with isolated bovine thyroid plasma membranes. Biochemical and biophysical research communications. vol 128. issue 3. 1985-07-10. PMID:2988535. |
binding studies suggested the presence of two classes of binding sites: a class with high affinity (kd = 13 nm) and low capacity (6411 sites/pg), and a class with low affinity (kd = 480 nm) and high capacity (105,300 sites/pg) at 15 degrees c. secretin, glucagon, insulin and somatostatin did not displace the tracer from the membranes. |
1985-07-10 |
2023-08-11 |
cattle |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
the release of somatostatin from the pancreas and stomach following the ingestion of a meal and its increase in the peripheral circulation elicits an attenuation of postprandial hormone secretion such as insulin, pancreatic polypeptide and gastrin and retards the rate at which nutrients enter the circulation. |
1985-07-09 |
2023-08-11 |
rat |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
in the obese zucker rat, however, tissue somatostatin levels are increased and therefore the present study was designed to determine the effect of synthetic somatostatin on basal and postprandial arterial insulin levels in obese and lean zucker rats. |
1985-07-09 |
2023-08-11 |
rat |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
in the obese rats somatostatin at a dose of 5 ng/kg x min reduced basal plasma insulin levels significantly, whereas no effect of somatostatin was observed on basal insulin levels in the lean animals at all doses employed. |
1985-07-09 |
2023-08-11 |
rat |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
the integrated postprandial insulin response was reduced during 0.25, 0.5, 1 and 5 ng/kg x min somatostatin in the obese animals, whereas only 0.5 ng/kg x min and higher doses had an inhibitory effect in the lean rats. |
1985-07-09 |
2023-08-11 |
rat |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
the degree of inhibition in relation to the postprandial insulin response during saline infusions was 35-230% in the obese and 30-100% in the lean zucker rats within the range of somatostatin infusions employed. |
1985-07-09 |
2023-08-11 |
rat |
| Y Oshim. Effect of diet restriction on 24-hr urinary C-peptide excretion in non-insulin-dependent non-obese diabetic subjects. The Tohoku journal of experimental medicine. vol 145. issue 3. 1985-07-08. PMID:2860737. |
insulin sensitivity for glucose utilization was measured by using cyclic somatostatin. |
1985-07-08 |
2023-08-11 |
human |
| P F Bougnères, F Landier, P Garnier, J C Job, J L Chaussai. Treatment of insulin excess by continuous subcutaneous infusion of somatostatin and glucagon in an infant. The Journal of pediatrics. vol 106. issue 5. 1985-07-03. PMID:2860216. |
treatment of insulin excess by continuous subcutaneous infusion of somatostatin and glucagon in an infant. |
1985-07-03 |
2023-08-11 |
Not clear |
| S W Lamberts, R Oosterom, M Neufeld, E del Poz. The somatostatin analog SMS 201-995 induces long-acting inhibition of growth hormone secretion without rebound hypersecretion in acromegalic patients. The Journal of clinical endocrinology and metabolism. vol 60. issue 6. 1985-06-24. PMID:2860119. |
in conclusion, the somatostatin derivative sms exerts a potent and prolonged inhibitory action on gh secretion and a shorter lasting suppression of insulin in acromegalic patients. |
1985-06-24 |
2023-08-11 |
human |
| C Dettori-Gera, P Ronner, A Scarp. Difference in dose-response curves for glucose-induced insulin and somatostatin release in rat pancreas. Biochimica et biophysica acta. vol 839. issue 3. 1985-06-19. PMID:2580562. |
difference in dose-response curves for glucose-induced insulin and somatostatin release in rat pancreas. |
1985-06-19 |
2023-08-11 |
rat |
| C Dettori-Gera, P Ronner, A Scarp. Difference in dose-response curves for glucose-induced insulin and somatostatin release in rat pancreas. Biochimica et biophysica acta. vol 839. issue 3. 1985-06-19. PMID:2580562. |
we studied the glucose dependence of insulin and somatostatin release from rat pancreata, which were perfused in vitro in the presence of 3-isobutyl-1-methylxanthine (ibmx; 0.5 mm). |
1985-06-19 |
2023-08-11 |
rat |
| K Yamatani, N Sato, K Takahashi, M Hara, H Sasak. Effect of gastrointestinal hormones on choleresis from the isolated perfused rat liver. Regulatory peptides. vol 10. issue 2-3. 1985-06-10. PMID:2859640. |
using isolated perfused rat liver, the direct effect of secretin, glucagon, caerulein, insulin and somatostatin on choleresis was investigated. |
1985-06-10 |
2023-08-11 |
rat |
| K Yamatani, N Sato, K Takahashi, M Hara, H Sasak. Effect of gastrointestinal hormones on choleresis from the isolated perfused rat liver. Regulatory peptides. vol 10. issue 2-3. 1985-06-10. PMID:2859640. |
these results indicate that glucagon has the most potent action on bile acid-independent canalicular bile, that caerulein and insulin do not act on canalicular bile production directly and that somatostatin does not directly suppress canalicular bile production nor hepatic glucose output produced by glucagon in rats. |
1985-06-10 |
2023-08-11 |
rat |
| M O Thorner, W S Evans, M Vance, J L Borges, R M Blizzard, A D Rogol, R M MacLeod, M J Cronin, L A Frohman, J L Thomine. Human pancreatic tumor GH-releasing factor. Acta neurochirurgica. vol 75. issue 1-4. 1985-06-06. PMID:2986423. |
hpgrf-40 does not elevate serum prolactin levels, thyrotropin (tsh), lh, or corticotropin (measured indirectly through plasma cortisol), or blood glucose or plasma concentrations of insulin, glucagon, pancreatic polypeptide, cholecystokinin, gastrin, gastric inhibitory peptide, motilin, or somatostatin. |
1985-06-06 |
2023-08-11 |
human |
| K E Steiner, H Fuchs, P E Williams, R W Stevenson, A D Cherrington, K G Albert. Regulation of ketogenesis by epinephrine and norepinephrine in the overnight-fasted, conscious dog. Diabetes. vol 34. issue 5. 1985-06-05. PMID:3886459. |
plasma insulin and glucagon levels were maintained constant by means of a somatostatin infusion (0.8 microgram/kg-min) and intraportal replacement infusions of insulin and glucagon. |
1985-06-05 |
2023-08-11 |
dog |