| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Leahy, G C Wei. Unresponsiveness to glucose in a streptozocin model of diabetes. Inappropriate insulin and glucagon responses to a reduction of glucose concentration. Diabetes. vol 34. issue 7. 1985-08-02. PMID:2861128. |
we studied the effect of an acute reduction in glucose concentration on insulin and glucagon secretion in this model and contrasted the results with the effects of epinephrine and somatostatin using the in vitro isolated, perfused pancreas. |
1985-08-02 |
2023-08-11 |
rat |
| G Michel, W Schwarz, W P Biege. Exercise-induced regulation of insulin receptor affinity: role of circulating metabolites. International journal of sports medicine. vol 6. issue 2. 1985-08-02. PMID:2861168. |
somatostatin (100 pg/ml) and prostaglandin b1 (10 nmol/l) were the only hormonal agents producing a small and reversible (somatostatin) increase in monocyte insulin binding. |
1985-08-02 |
2023-08-11 |
Not clear |
| T D O'Brien, K H Johnson, D W Hayde. Pancreatic ganglioneuronal amyloid. Occurrence in diabetic cats with islet amyloidosis. The American journal of pathology. vol 119. issue 3. 1985-07-30. PMID:2409805. |
ganglioneuronal amyloid had staining characteristics identical to those previously reported for islet amyloid, including 1) congophilia, 2) resistance to oxidation by kmno4, 3) immunoreactivity (pap technique) with antiserum to a b-chain-rich insulin fraction, and 4) no reactivity with antisera to insulin, glucagon, or somatostatin. |
1985-07-30 |
2023-08-11 |
Not clear |
| T D O'Brien, K H Johnson, D W Hayde. Pancreatic ganglioneuronal amyloid. Occurrence in diabetic cats with islet amyloidosis. The American journal of pathology. vol 119. issue 3. 1985-07-30. PMID:2409805. |
nonneuronal cells with insulin, glucagon, and somatostatin immunoreactivity were seen in many pancreatic ganglia and nerves; and in a few instances, b cells were found near ganglioneuronal amyloid deposits. |
1985-07-30 |
2023-08-11 |
Not clear |
| M A Berk, W E Clutter, D Skor, S D Shah, R P Gingerich, C A Parvin, P E Crye. Enhanced glycemic responsiveness to epinephrine in insulin-dependent diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to epinephrine in humans. The Journal of clinical investigation. vol 75. issue 6. 1985-07-30. PMID:3891786. |
during the islet clamp study (somatostatin infusion with insulin and glucagon replacement at fixed rates), the heightened glycemic response was unaltered in the patients with iddm, but the nondiabetic subjects exhibited an enhanced glycemic response to epinephrine indistinguishable from that of patients with iddm. |
1985-07-30 |
2023-08-11 |
human |
| R R Wolfe, J H Shaw, M J Durko. Effect of sepsis on VLDL kinetics: responses in basal state and during glucose infusion. The American journal of physiology. vol 248. issue 6 Pt 1. 1985-07-24. PMID:3890559. |
when glucose was infused into dogs with insulin and glucagon levels clamped at basal levels (by means of infusion of somatostatin and replacement of the hormones), ravldl increased significantly in the control dogs, but it did not increase further in dogs with sepsis. |
1985-07-24 |
2023-08-11 |
Not clear |
| G Gragnoli, A M Signorini, I Tanganell. Effects of somatostatin on the behaviour of thromboxane B2 and beta-thromboglobulin in type I diabetes. Acta endocrinologica. vol 109. issue 1. 1985-07-16. PMID:2408435. |
pharmacological studies have shown that the addition of somatostatin to insulin promotes a more rapid recovery from diabetic ketoacidosis. |
1985-07-16 |
2023-08-11 |
human |
| F B Loud, J J Holst, E Egense, B Petersen, J Christianse. Is somatostatin a humoral regulator of the endocrine pancreas and gastric acid secretion in man? Gut. vol 26. issue 5. 1985-07-12. PMID:2860053. |
the effect of low dose infusions of somatostatin on meal stimulated gastric acid secretion was studied in eight healthy volunteers by intragastric titration after a peptone test meal with radioimmunoassay control of the plasma concentrations of somatostatin and the pancreatic hormones glucagon and insulin. |
1985-07-12 |
2023-08-11 |
human |
| I Lundquist, B Ahrén, R Håkanson, F Sundle. Quinacrine accumulation in pancreatic islet cells of rat and mouse: relationship to functional activity and effects on basal and stimulated insulin secretion. Diabetologia. vol 28. issue 3. 1985-07-11. PMID:3888758. |
the fluorescent acridine derivative, quinacrine, was found to accumulate in rat and mouse pancreatic islet cells storing insulin, glucagon, pancreatic polypeptide, or somatostatin. |
1985-07-11 |
2023-08-11 |
mouse |
| K Hermanse. Forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. Endocrinology. vol 116. issue 6. 1985-07-10. PMID:2581771. |
forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. |
1985-07-10 |
2023-08-11 |
dog |
| K Hermanse. Forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. Endocrinology. vol 116. issue 6. 1985-07-10. PMID:2581771. |
the effects of forskolin on the release of somatostatin, glucagon, and insulin were studied using the isolated, perfused dog pancreas. |
1985-07-10 |
2023-08-11 |
dog |
| K Hermanse. Forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. Endocrinology. vol 116. issue 6. 1985-07-10. PMID:2581771. |
it was found that concentrations ranging from 0.075 microm-1 microm stimulated the secretion of somatostatin, glucagon, and insulin in a dose-related manner. |
1985-07-10 |
2023-08-11 |
dog |
| P Molinero, J R Calvo, R Goberna, J M Guerrer. The interaction of vasoactive intestinal peptide (VIP) with isolated bovine thyroid plasma membranes. Biochemical and biophysical research communications. vol 128. issue 3. 1985-07-10. PMID:2988535. |
binding studies suggested the presence of two classes of binding sites: a class with high affinity (kd = 13 nm) and low capacity (6411 sites/pg), and a class with low affinity (kd = 480 nm) and high capacity (105,300 sites/pg) at 15 degrees c. secretin, glucagon, insulin and somatostatin did not displace the tracer from the membranes. |
1985-07-10 |
2023-08-11 |
cattle |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
the release of somatostatin from the pancreas and stomach following the ingestion of a meal and its increase in the peripheral circulation elicits an attenuation of postprandial hormone secretion such as insulin, pancreatic polypeptide and gastrin and retards the rate at which nutrients enter the circulation. |
1985-07-09 |
2023-08-11 |
rat |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
in the obese zucker rat, however, tissue somatostatin levels are increased and therefore the present study was designed to determine the effect of synthetic somatostatin on basal and postprandial arterial insulin levels in obese and lean zucker rats. |
1985-07-09 |
2023-08-11 |
rat |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
in the obese rats somatostatin at a dose of 5 ng/kg x min reduced basal plasma insulin levels significantly, whereas no effect of somatostatin was observed on basal insulin levels in the lean animals at all doses employed. |
1985-07-09 |
2023-08-11 |
rat |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
the integrated postprandial insulin response was reduced during 0.25, 0.5, 1 and 5 ng/kg x min somatostatin in the obese animals, whereas only 0.5 ng/kg x min and higher doses had an inhibitory effect in the lean rats. |
1985-07-09 |
2023-08-11 |
rat |
| H Bender, V Schusdziarra, E F Pfeiffe. Increased sensitivity to somatostatin in obese Zucker rats. Clinical physiology and biochemistry. vol 3. issue 1. 1985-07-09. PMID:2859937. |
the degree of inhibition in relation to the postprandial insulin response during saline infusions was 35-230% in the obese and 30-100% in the lean zucker rats within the range of somatostatin infusions employed. |
1985-07-09 |
2023-08-11 |
rat |
| Y Oshim. Effect of diet restriction on 24-hr urinary C-peptide excretion in non-insulin-dependent non-obese diabetic subjects. The Tohoku journal of experimental medicine. vol 145. issue 3. 1985-07-08. PMID:2860737. |
insulin sensitivity for glucose utilization was measured by using cyclic somatostatin. |
1985-07-08 |
2023-08-11 |
human |
| P F Bougnères, F Landier, P Garnier, J C Job, J L Chaussai. Treatment of insulin excess by continuous subcutaneous infusion of somatostatin and glucagon in an infant. The Journal of pediatrics. vol 106. issue 5. 1985-07-03. PMID:2860216. |
treatment of insulin excess by continuous subcutaneous infusion of somatostatin and glucagon in an infant. |
1985-07-03 |
2023-08-11 |
Not clear |