| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Nilsson, A K Mohammed, B G Henriksson, B Winblad, L Bergströ. Influence of place learning on somatostatin levels in the rat brain following environmental deprivation. Regulatory peptides. vol 58. issue 1-2. 1996-03-01. PMID:8570855. |
our data showed increased somatostatin immunoreactivity, and unchanged substance p immunoreactivity in the posterior part of the cerebral cortex. |
1996-03-01 |
2023-08-12 |
rat |
| G Muñoz-Acedo, R M Izquierdo-Claros, J A Sánchez-Alonso, N del Hoyo, M A Pérez-Albarsanz, E Arill. Effect of somatostatin on the mass accumulation of inositol-1,4,5-trisphosphate in rat hypothalamus, striatum, frontoparietal cortex and hippocampus. Neuroscience letters. vol 197. issue 1. 1996-02-12. PMID:8545051. |
effect of somatostatin on the mass accumulation of inositol-1,4,5-trisphosphate in rat hypothalamus, striatum, frontoparietal cortex and hippocampus. |
1996-02-12 |
2023-08-12 |
rat |
| N Matsuoka, M Yamazaki, I Yamaguch. Changes in brain somatostatin in memory-deficient rats: comparison with cholinergic markers. Neuroscience. vol 66. issue 3. 1995-09-21. PMID:7644025. |
neurochemistry measurements showed that lesions of the nucleus basalis magnocellularis produced a selective reduction both in the cortical cholinergic marker choline acetyltransferase and in striatal somatostatin level, whereas lesioning of the fimbria-fornix caused a marked loss of choline acetyltransferase in the hippocampus and posterior cortex, and a significant reduction in hippocampal somatostatin. |
1995-09-21 |
2023-08-12 |
rat |
| L Puebla, E Arill. Exogenous histamine increases the somatostatin receptor/effector system in the rat frontoparietal cortex. European journal of pharmacology. vol 289. issue 2. 1995-08-30. PMID:7621910. |
exogenous histamine increases the somatostatin receptor/effector system in the rat frontoparietal cortex. |
1995-08-30 |
2023-08-12 |
rat |
| L Puebla, E Arill. Exogenous histamine increases the somatostatin receptor/effector system in the rat frontoparietal cortex. European journal of pharmacology. vol 289. issue 2. 1995-08-30. PMID:7621910. |
the present study examined the effects of histamine on somatostatin-like immunoreactivity levels, binding of 125i-[tyr11]somatostatin to its specific receptors, somatostatin inhibition of basal and forskolin-stimulated adenylyl cyclase activity and inhibitory guanine-nucleotide binding protein (gi) function in the rat frontoparietal cortex. |
1995-08-30 |
2023-08-12 |
rat |
| L Puebla, E Arill. Exogenous histamine increases the somatostatin receptor/effector system in the rat frontoparietal cortex. European journal of pharmacology. vol 289. issue 2. 1995-08-30. PMID:7621910. |
dose of 10 micrograms or 1 microgram of histamine induced an increase in the number of specific 125i-[tyr11]somatostatin receptors (590 +/- 22 vs 358 +/- 12 fmol/mg protein, p < 0.001 and 455 +/- 20 vs. 342 +/- 21 fmol/mg protein, p < 0.01, respectively) together with a decrease in their apparent affinity (0.76 +/- 0.04 vs 0.39 +/- 0.02 nm, p < 0.001 and 0.60 +/- 0.03 vs 0.39 +/- 0.05 nm, p < 0.01, respectively) in rat frontoparietal cortex membranes. |
1995-08-30 |
2023-08-12 |
rat |
| J Pérez, A Vezzani, G Civenni, P Tutka, M Rizzi, E Schüpbach, D Hoye. Functional effects of D-Phe-c[Cys-Tyr-D-Trp-Lys-Val-Cys]-Trp-NH2 and differential changes in somatostatin receptor messenger RNAs, binding sites and somatostatin release in kainic acid-treated rats. Neuroscience. vol 65. issue 4. 1995-08-22. PMID:7617164. |
in situ hybridization histochemistry for somatostatin receptors-1, -2, -3 and -4 section and receptor autoradiography using [125i]cgp 23996, [125i]somatostatin-28, [125i]seglitide and [125i]tyr3 octreotide were carried out to determine the expression of somatostatin receptor messenger rnas and binding sites in the hippocampus and cerebral cortex of rats 21 days following generalized limbic seizures induced by subcutaneous injection of 12mg/kg kainic acid. |
1995-08-22 |
2023-08-12 |
rat |
| J Pérez, A Vezzani, G Civenni, P Tutka, M Rizzi, E Schüpbach, D Hoye. Functional effects of D-Phe-c[Cys-Tyr-D-Trp-Lys-Val-Cys]-Trp-NH2 and differential changes in somatostatin receptor messenger RNAs, binding sites and somatostatin release in kainic acid-treated rats. Neuroscience. vol 65. issue 4. 1995-08-22. PMID:7617164. |
no effect of kainate was observed in the expression of somatostatin receptor messenger rnas in the cerebral cortex. |
1995-08-22 |
2023-08-12 |
rat |
| J Pérez, A Vezzani, G Civenni, P Tutka, M Rizzi, E Schüpbach, D Hoye. Functional effects of D-Phe-c[Cys-Tyr-D-Trp-Lys-Val-Cys]-Trp-NH2 and differential changes in somatostatin receptor messenger RNAs, binding sites and somatostatin release in kainic acid-treated rats. Neuroscience. vol 65. issue 4. 1995-08-22. PMID:7617164. |
in control rats, the selective somatostatin-2 receptor ligands, [125i]seglitide and [125i]tyr3 octreotide and the non-selective somatostatin receptor ligands [125i]cgp 23996 and [125i]somatostatin-28, labelled preferentially the stratum oriens and radiatum ca1, the granule and molecular layers of the dentate gyrus and the deep layers of the cerebral cortex. |
1995-08-22 |
2023-08-12 |
rat |
| K A Harrington, M Schindler, P P Humphrey, P C Emso. Expression of messenger RNA for somatostatin receptor subtype 4 in adult rat brain. Neuroscience letters. vol 188. issue 1. 1995-07-20. PMID:7783970. |
somatostatin receptor subtype 4 was found mainly in the hippocampus ca1 > ca2 > ca3 pyramidal cells and in the pyramidal cells in layers (iv-vi) of the cerebral cortex. |
1995-07-20 |
2023-08-12 |
rat |
| I A Alonso, J C Prieto, E Arill. Effect of acute and chronic diisopropylfluorophosphate and atropine administration on somatostatin binding in the rat frontoparietal cortex and hippocampus. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870867. |
effect of acute and chronic diisopropylfluorophosphate and atropine administration on somatostatin binding in the rat frontoparietal cortex and hippocampus. |
1995-03-29 |
2023-08-12 |
rat |
| S Shibata, T Tanaka, S Watanab. Facilitatory effects of somatostatin on reduced uptake of 2-deoxyglucose in cerebral cortical and hippocampal slices from aged rats. European journal of pharmacology. vol 269. issue 2. 1995-03-10. PMID:7851504. |
the present results demonstrated that 2-deoxyglucose uptake by the cerebral cortex was facilitated by somatostatin and carbachol in both young and old rats. |
1995-03-10 |
2023-08-12 |
rat |
| P Dournaud, P Cervera-Pierot, E Hirsch, F Javoy-Agid, C Kordon, Y Agid, J Epelbau. Somatostatin messenger RNA-containing neurons in Alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. Neuroscience. vol 61. issue 4. 1995-03-02. PMID:7838375. |
somatostatin messenger rna-containing neurons in alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. |
1995-03-02 |
2023-08-12 |
human |
| P Dournaud, P Cervera-Pierot, E Hirsch, F Javoy-Agid, C Kordon, Y Agid, J Epelbau. Somatostatin messenger RNA-containing neurons in Alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. Neuroscience. vol 61. issue 4. 1995-03-02. PMID:7838375. |
somatostatin messenger rna-containing neurons displayed a similar regional and subregional distribution in control subjects and patients with alzheimer's disease, being more abundant in the frontal cortex, followed by the hippocampus and the parahippocampal cortex. |
1995-03-02 |
2023-08-12 |
human |
| P Dournaud, P Cervera-Pierot, E Hirsch, F Javoy-Agid, C Kordon, Y Agid, J Epelbau. Somatostatin messenger RNA-containing neurons in Alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. Neuroscience. vol 61. issue 4. 1995-03-02. PMID:7838375. |
a significantly lower level of expression of somatostatin messenger rna per somatostatinergic cell was observed in the hippocampus of alzheimer's disease patients (-47%, p < 0.05), but not in frontal cortex gray (-17%) and white (-36%) matter and parahippocampal cortex gray (-42%) and white (-29%) matter. |
1995-03-02 |
2023-08-12 |
human |
| S López-Sañudo, E Arill. Somatostatin receptors coupled to the inhibition of adenylyl cyclase in the rat frontoparietal cortex are modulated by alpha 2 adrenoceptors. Brain research. Molecular brain research. vol 25. issue 1-2. 1995-01-05. PMID:7984040. |
somatostatin receptors coupled to the inhibition of adenylyl cyclase in the rat frontoparietal cortex are modulated by alpha 2 adrenoceptors. |
1995-01-05 |
2023-08-12 |
rat |
| S D Croll, S J Wiegand, K D Anderson, R M Lindsay, H Naw. Regulation of neuropeptides in adult rat forebrain by the neurotrophins BDNF and NGF. The European journal of neuroscience. vol 6. issue 8. 1994-12-30. PMID:7981876. |
bdnf produced elevations of peptide and mrna for neuropeptide y and cholecystokinin in hippocampus and cortex, and somatostatin in cortex. |
1994-12-30 |
2023-08-12 |
rat |
| F Javoy-Agi. Cholinergic and peptidergic systems in PSP. Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7964688. |
of particular interest, is somatostatin, the levels of which are subnormal in cerebral cortex of patients with dementia of alzheimer' or parkinson's disease type. |
1994-12-22 |
2023-08-12 |
Not clear |
| B Berger, C Alvare. Neurochemical development of the hippocampal region in the fetal rhesus monkey. II. Immunocytochemistry of peptides, calcium-binding proteins, DARPP-32, and monoamine innervation in the entorhinal cortex by the end of gestation. Hippocampus. vol 4. issue 1. 1994-09-22. PMID:7914799. |
the immunocytochemical detection of somatostatin, neurotensin (nt), parvalbumin, calbindin d-28k, darpp-32 as well as tyrosine hydroxylase (th), dopamine-beta-hydroxylase and serotonin (5-ht), was carried out on serial cryostat sections of the entorhinal cortex. |
1994-09-22 |
2023-08-12 |
monkey |
| B Berger, C Alvare. Neurochemical development of the hippocampal region in the fetal rhesus monkey. II. Immunocytochemistry of peptides, calcium-binding proteins, DARPP-32, and monoamine innervation in the entorhinal cortex by the end of gestation. Hippocampus. vol 4. issue 1. 1994-09-22. PMID:7914799. |
the authors reported in a previous paper the precocious differentiation of the entorhinal cortex in rhesus monkey fetuses and featured the conspicuous expression of calbindin d-28k, somatostatin, neurotensin, and the monoaminergic innervation during the first half of gestation. |
1994-09-22 |
2023-08-12 |
monkey |