| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H R Mäcke, P Smith-Jones, T Maina, B Stolz, R Albert, C Bruns, H Reis. New octreotide derivatives for in vivo targeting of somatostatin receptor-positive tumors for single photon emission computed tomography (SPECT) and positron emission tomography (PET). Hormone and metabolic research. Supplement series. vol 27. 1993-08-13. PMID:8392486. |
moreover the binding affinity to somatostatin receptors on rat brain cortex membranes was shown to be retained. |
1993-08-13 |
2023-08-12 |
rat |
| K Maeda, E Kawata, K Sakai, K Chihar. Effects of putative cognitive function-enhancing drugs and dopaminergic agents on somatostatin and neuropeptide Y in rat brain. European journal of pharmacology. vol 233. issue 2-3. 1993-05-11. PMID:8096819. |
1-dihydroxyphenylalanine increased somatostatin levels in whole brain, and hypothalamic npy levels, and reduced npy levels in the cerebral cortex, hippocampus and striatum. |
1993-05-11 |
2023-08-12 |
rat |
| S Shibata, Y Koga, T Hamada, S Watanab. Facilitation of 2-deoxyglucose uptake in rat cortex and hippocampus slices by somatostatin is independent of cholinergic activity. European journal of pharmacology. vol 231. issue 3. 1993-04-15. PMID:8095464. |
facilitation of 2-deoxyglucose uptake in rat cortex and hippocampus slices by somatostatin is independent of cholinergic activity. |
1993-04-15 |
2023-08-12 |
rat |
| S Shibata, Y Koga, T Hamada, S Watanab. Facilitation of 2-deoxyglucose uptake in rat cortex and hippocampus slices by somatostatin is independent of cholinergic activity. European journal of pharmacology. vol 231. issue 3. 1993-04-15. PMID:8095464. |
the present experiments showed that somatostatin elevated 2-dg uptake in rat cortex and hippocampus slices. |
1993-04-15 |
2023-08-12 |
rat |
| S Lang, K Peigen, J Liu, F Zhang, X Chen, Z Li. Somatostatin concentrations in cerebrospinal fluid and brain tissue of patients with refractory epilepsy. Molecular and chemical neuropathology. vol 17. issue 3. 1993-03-10. PMID:1362876. |
an increased level of somatostatin was found in the epileptic foci of cerebral cortex, determined by the cortical eeg. |
1993-03-10 |
2023-08-11 |
Not clear |
| M M Haglund, M S Berger, D D Kunkel, J E Franck, S Ghatan, G A Ojeman. Changes in gamma-aminobutyric acid and somatostatin in epileptic cortex associated with low-grade gliomas. Journal of neurosurgery. vol 77. issue 2. 1992-08-13. PMID:1352540. |
changes in gamma-aminobutyric acid and somatostatin in epileptic cortex associated with low-grade gliomas. |
1992-08-13 |
2023-08-11 |
Not clear |
| K V Pasha, E Vijaya. Acute and short-term effects of intraventricular injection of somatostatin and LHRH on glutamate and GABA levels in rat brain. Biochemistry international. vol 26. issue 1. 1992-07-28. PMID:1352101. |
cerebral cortex, cerebellar and hypothalamic glutamate levels were significantly elevated at 30 min following injection of 1 micrograms somatostatin, whereas hypothalamic glutamate levels were elevated at 10 min following a 0.5 micrograms dose. |
1992-07-28 |
2023-08-11 |
rat |
| E Lamperti, D Cocchi, E A Parati, T Caraceni, E E Mülle. Growth hormone responses to cholinergically active drugs in patients with dementia of the Alzheimer type. Alzheimer disease and associated disorders. vol 6. issue 1. 1992-07-21. PMID:1605943. |
patients with dementia of the alzheimer type (dat) reportedly have reduced concentrations and function of some brain messengers, particularly acetylcholine and somatostatin, not only in the cerebral cortex, but also in subcortical structures, e.g., the hippocampus and the hypothalamus. |
1992-07-21 |
2023-08-11 |
human |
| J Bourdais, P Cohe. [Post-translational proteolytic maturation of prosomatostatin. Cellular and molecular approach]. Annales d'endocrinologie. vol 52. issue 5. 1992-07-21. PMID:1687882. |
using a combination of techniques including subcellular fractionation, intracellular transport blockage and electron microscopy immunocytochemical observations, we have demonstrated unequivocally that both monobasic and dibasic proteolytic maturation occur in the golgi apparatus of either rat brain cortex or hypothalamic cells or for somatostatin producing cells of lophius piscatorius brockmann organs. |
1992-07-21 |
2023-08-11 |
rat |
| M N Rodríguez-Sánchez, I Alvaro, E Arill. Effect of prenatal and postnatal cocaine exposure on somatostatin content and binding in frontoparietal cortex and hippocampus of developing rat pups. Peptides. vol 12. issue 5. 1992-04-21. PMID:1686936. |
effect of prenatal and postnatal cocaine exposure on somatostatin content and binding in frontoparietal cortex and hippocampus of developing rat pups. |
1992-04-21 |
2023-08-11 |
rat |
| A I Grishchuk, V I Tokar', I G Danilov. [The function of the pancreatic islet cells during prolonged hypokinesia]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. issue 4. 1992-04-15. PMID:1686803. |
the content of insulin, c-peptide, glucagon, somatostatin, and glucose was studied in the blood of animals experiencing 3, 10, 30, 70, and 140-day hypokinesia (hk) and the camp content--in their liver and renal cortex. |
1992-04-15 |
2023-08-11 |
Not clear |
| A I Grishchuk, V I Tokar', I G Danilov. [The function of the pancreatic islet cells during prolonged hypokinesia]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. issue 4. 1992-04-15. PMID:1686803. |
in 30-day hk the blood insulin and glucagon content, the content of camp in the liver and renal cortex are sharply increased, and the level of somatostatin and glucose is reduced. |
1992-04-15 |
2023-08-11 |
Not clear |
| S Iritani, K Sato. Distribution of somatostatin-immunoreactive cell bodies and fibers in the neocortex of Macaca fuscata. Synapse (New York, N.Y.). vol 9. issue 1. 1992-04-08. PMID:1686672. |
the distribution of somatostatin-immunoreactive cell bodies and processes was studied in the cerebral cortex of the macaque monkey (macaca fuscata), by applying an immunohistochemical technique with a monoclonal antibody raised against somatostatin tetradecapeptide. |
1992-04-08 |
2023-08-11 |
monkey |
| T Z Baram, L Schult. Ontogeny of somatostatin gene expression in rat diencephalon. Developmental neuroscience. vol 13. issue 3. 1992-01-27. PMID:1684321. |
other structures expressing somatostatin messenger rna include the anterior basal periventricular nucleus, amygdalo-hippocampal complex, dorsolateral thalamus and distinct areas in the parieto-frontal cortex. |
1992-01-27 |
2023-08-11 |
rat |
| W H Bakker, R Albert, C Bruns, W A Breeman, L J Hofland, P Marbach, J Pless, D Pralet, B Stolz, J W Kope. [111In-DTPA-D-Phe1]-octreotide, a potential radiopharmaceutical for imaging of somatostatin receptor-positive tumors: synthesis, radiolabeling and in vitro validation. Life sciences. vol 49. issue 22. 1991-12-18. PMID:1658515. |
the binding of [111in-dtpa-d-phe1]-octreotide to rat brain cortex membranes proved to be displaced similarly by natural somatostatin as well as by octreotide, suggesting specific binding of [111in-dtpa-d-phe1]-octreotide to somatostatin receptors. |
1991-12-18 |
2023-08-11 |
human |
| F Tang, W S Ma. The regional distribution of thyrotropin releasing hormone, leu-enkephalin, met-enkephalin, substance P, somatostatin and cholecystokinin in the rat brain and pituitary. Neuropeptides. vol 19. issue 4. 1991-11-19. PMID:1717878. |
the highest levels of immunoreactive leu-enkephalin, trh, substance p and somatostatin were found in the hypothalamus, while the striatum and the cerebral cortex had the highest concentrations of met-enkephalin and cholecystokinin respectively. |
1991-11-19 |
2023-08-11 |
rat |
| V Barrios, M N Rodríguez-Sánchez, E Arill. Effect of maternal exposure to nicotine in the rat on level and binding of somatostatin in brain of developing offspring. Neuropharmacology. vol 30. issue 6. 1991-10-31. PMID:1681443. |
the effect of maternal exposure to nicotine on the level of somatostatin and specific binding in frontoparietal cortex and hippocampus of developing offspring was investigated. |
1991-10-31 |
2023-08-11 |
rat |
| V Barrios, M N Rodríguez-Sánchez, E Arill. Effect of maternal exposure to nicotine in the rat on level and binding of somatostatin in brain of developing offspring. Neuropharmacology. vol 30. issue 6. 1991-10-31. PMID:1681443. |
the maximum specific binding of somatostatin to the receptors in membranes from the frontoparietal cortex, peaked at 10 days of age in the offspring of control rats. |
1991-10-31 |
2023-08-11 |
rat |
| V Barrios, M N Rodríguez-Sánchez, E Arill. Effect of maternal exposure to nicotine in the rat on level and binding of somatostatin in brain of developing offspring. Neuropharmacology. vol 30. issue 6. 1991-10-31. PMID:1681443. |
the levels of somatostatin-like immunoreactivity and the number of somatostatin receptors in the frontoparietal cortex and hippocampus was comparable in the 30-day-old offspring of the control and nicotine-treated rats. |
1991-10-31 |
2023-08-11 |
rat |
| G Bonanno, B Parodi, S Cafaggi, M Raiter. Somatostatin release from rat cerebral cortex synaptosomes. Journal of neurochemistry. vol 57. issue 4. 1991-10-21. PMID:1680160. |
somatostatin release from rat cerebral cortex synaptosomes. |
1991-10-21 |
2023-08-11 |
rat |