| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C J Clark, R S Phillips, R B McMillan, I O Montgomery, T W Ston. Differences in the neurochemical characteristics of the cortex and striatum of mice with cerebral malaria. Parasitology. vol 130. issue Pt 1. 2005-03-16. PMID:15700754. |
in the cortex of infected mice, we found a significant reduction in the number of cells containing substance p, somatostatin and neuropeptide y. |
2005-03-16 |
2023-08-12 |
mouse |
| K Miyasaka, K Tateishi, H Tomita, N Sazaki, K Okubo, M Matsumoto, A Funakosh. Evidence for the effect of aging on tissue contents of gastrin, cholecystokinin and somatostatin in the rat. Archives of gerontology and geriatrics. vol 16. issue 1. 2005-03-10. PMID:15374355. |
somatostatin concentrations in the intestine and cerebral cortex did not change with age. |
2005-03-10 |
2023-08-12 |
rat |
| Halina Baran, Berthold Kepplinger, Markus Draxler, Gerhard Skofitsc. Choline acetyltransferase, glutamic acid decarboxylase and somatostatin in the kainic acid model for chronic temporal lobe epilepsy. Neuro-Signals. vol 13. issue 6. 2005-02-15. PMID:15627816. |
the somatostatin level was significantly increased in all cortical regions (between 162 and 221% of control) as well as in the hippocampus (119% of control), but reduced in the amygdala/piriform cortex (45% of control; p<0.01). |
2005-02-15 |
2023-08-12 |
Not clear |
| Halina Baran, Berthold Kepplinger, Markus Draxler, Gerhard Skofitsc. Choline acetyltransferase, glutamic acid decarboxylase and somatostatin in the kainic acid model for chronic temporal lobe epilepsy. Neuro-Signals. vol 13. issue 6. 2005-02-15. PMID:15627816. |
six months after ka injection, the somatostatin:gad ratio was lowered in the amygdala/piriform cortex (49% of control) and in the caudate nucleus (41% of control), whereas it was normal in the hippocampus and moderately increased in the cortical brain regions. |
2005-02-15 |
2023-08-12 |
Not clear |
| Halina Baran, Berthold Kepplinger, Markus Draxler, Gerhard Skofitsc. Choline acetyltransferase, glutamic acid decarboxylase and somatostatin in the kainic acid model for chronic temporal lobe epilepsy. Neuro-Signals. vol 13. issue 6. 2005-02-15. PMID:15627816. |
a positive correlation was found between seizure severity and the reduction of both chat activities and somatostatin levels in the amygdala/piriform cortex. |
2005-02-15 |
2023-08-12 |
Not clear |
| David Aguado-Llera, Mercedes Martín-Martínez, María Teresa García-López, Eduardo Arilla-Ferreiro, Vicente Barrio. Gly-Pro-Glu protects beta-amyloid-induced somatostatin depletion in the rat cortex. Neuroreport. vol 15. issue 12. 2004-11-29. PMID:15305149. |
gly-pro-glu protects beta-amyloid-induced somatostatin depletion in the rat cortex. |
2004-11-29 |
2023-08-12 |
rat |
| D Hoyer, C Nunn, J Hannon, P Schoeffter, D Feuerbach, E Schuepbach, D Langenegger, R Bouhelal, K Hurth, P Neumann, T Troxler, P Pfaeffl. SRA880, in vitro characterization of the first non-peptide somatostatin sst(1) receptor antagonist. Neuroscience letters. vol 361. issue 1-3. 2004-08-30. PMID:15135911. |
sra880 has high affinity for native rat, mouse, monkey and human cerebral cortex somatostatin sst(1) receptors (pk(d) = 7.8-8.6) and for human recombinant sst(1) receptors (pk(d) = 8.0-8.1). |
2004-08-30 |
2023-08-12 |
mouse |
| Danica M Petrovic-Djergovic, Ana K Rakin, Irena P Zivkovic, Mileva V Mici. Changes in the thymus of peripubertal rats induced by centrally applied somatostatin-28. The Histochemical journal. vol 34. issue 11-12. 2004-06-28. PMID:14626348. |
somatostatin in the deeper cortex decreased the number of thymocytes, per volume unit, while in outer cortex raised their number. |
2004-06-28 |
2023-08-12 |
rat |
| R Winsky-Sommerer, D Grouselle, C Rougeot, V Laurent, J-P David, A Delacourte, P Dournaud, N G Seidah, I Lindberg, S Trottier, J Epelbau. The proprotein convertase PC2 is involved in the maturation of prosomatostatin to somatostatin-14 but not in the somatostatin deficit in Alzheimer's disease. Neuroscience. vol 122. issue 2. 2004-03-01. PMID:14614908. |
a somatostatin deficit occurs in the cerebral cortex of alzheimer's disease patients without a major loss in somatostatin-containing neurons. |
2004-03-01 |
2023-08-12 |
mouse |
| Caroline Nunn, Daniel Langenegger, Konstanze Hurth, Kerstin Schmidt, Dominique Fehlmann, Daniel Hoye. Agonist properties of putative small-molecule somatostatin sst2 receptor-selective antagonists. European journal of pharmacology. vol 465. issue 3. 2004-02-10. PMID:12681432. |
in radioligand binding studies using the agonist radioligands [125i][tyr(11)]srif-14 (ala-gly-c[cys-lys-asn-phe-phe-trp-lys-thr-(125i-tyr)-thr-ser-cys]-oh), [125i]ltt-srif-28 ([leu(8),dtrp(22),125i-tyr(25)]srif-28; ser-ala-asn-ser-asn-pro-ala-leu-ala-pro-arg-glu-arg-lys-ala-gly-c[cys-lys-asn-phe-phe-dtrp-lys-thr-(125i-tyr)-thr-ser-cys]-oh), [125i]cgp 23996 (c[lys-asu-phe-phe-trp-lys-thr-(125i-tyr)-thr-ser]), [125i][tyr(3)]octreotide (dphe-c[cys-(125i-tyr)-dtrp-lys-thr-cys]-thr-oh) and [125i][tyr(10)]cortistatin-14 (pro-c[cys-lys-asn-phe-phe-trp-lys-thr-(125i-tyr)-ser-ser-cys]-lys) at human recombinant somatostatin receptors expressed in chinese hamster lung fibroblast (ccl39) cells and native rat cortex, the compounds bound with high affinity (pk(d) 6.8-9.7) and selectivity to human sst(2) receptors. |
2004-02-10 |
2023-08-12 |
human |
| Dan Shlosberg, Saundra L Patrick, Yossi Buskila, Yael Amita. Inhibitory effect of mouse neocortex layer I on the underlying cellular network. The European journal of neuroscience. vol 18. issue 10. 2004-01-26. PMID:14656324. |
immunocytochemistry for chemical markers of interneurons proved that the inhibitory input to layer i is predominantly somatostatin immunoreactive (sm-ir), such that layer i contains approximately one-third of all sm-ir axons in the cortex. |
2004-01-26 |
2023-08-12 |
mouse |
| F Martín, R Coveñas, J A Narváez, G Tram. An immunocytochemical mapping of somatostatin in the cat auditory cortex. Archives italiennes de biologie. vol 141. issue 4. 2003-12-05. PMID:14502830. |
an immunocytochemical mapping of somatostatin in the cat auditory cortex. |
2003-12-05 |
2023-08-12 |
cat |
| Rosa María Izquierdo-Claros, María del Carmen Boyano-Adánez, Eduardo Arilla-Ferreir. Effects of subchronic and chronic melatonin treatment on somatostatin binding and its effects on adenylyl cyclase activity in the rat frontoparietal cortex. Journal of pineal research. vol 33. issue 4. 2003-04-07. PMID:12390500. |
effects of subchronic and chronic melatonin treatment on somatostatin binding and its effects on adenylyl cyclase activity in the rat frontoparietal cortex. |
2003-04-07 |
2023-08-12 |
rat |
| Rosa María Izquierdo-Claros, María del Carmen Boyano-Adánez, Eduardo Arilla-Ferreir. Effects of subchronic and chronic melatonin treatment on somatostatin binding and its effects on adenylyl cyclase activity in the rat frontoparietal cortex. Journal of pineal research. vol 33. issue 4. 2003-04-07. PMID:12390500. |
we have previously demonstrated that acute melatonin treatment regulates somatostatin receptor function in the rat frontoparietal cortex. |
2003-04-07 |
2023-08-12 |
rat |
| Rosa María Izquierdo-Claros, María del Carmen Boyano-Adánez, Eduardo Arilla-Ferreir. Effects of subchronic and chronic melatonin treatment on somatostatin binding and its effects on adenylyl cyclase activity in the rat frontoparietal cortex. Journal of pineal research. vol 33. issue 4. 2003-04-07. PMID:12390500. |
however, the effects of subchronic and chronic melatonin treatment on the somatostatin receptor-g protein-adenylyl cyclase system in the rat frontoparietal cortex are unknown. |
2003-04-07 |
2023-08-12 |
rat |
| Rosa María Izquierdo-Claros, María del Carmen Boyano-Adánez, Eduardo Arilla-Ferreir. Effects of subchronic and chronic melatonin treatment on somatostatin binding and its effects on adenylyl cyclase activity in the rat frontoparietal cortex. Journal of pineal research. vol 33. issue 4. 2003-04-07. PMID:12390500. |
altogether, the present findings suggest that subchronic melatonin treatment modulates the somatostatin receptor/effector system in the rat frontoparietal cortex. |
2003-04-07 |
2023-08-12 |
rat |
| Robert Pichler, Wilhelmine Maschek, Carmen Crespillo, Isabel Esteva, Federico Sorigue. Is there a gender difference of somatostatin-receptor density in the human brain? Neuro endocrinology letters. vol 23. issue 5-6. 2003-03-06. PMID:12500167. |
as neuronal production of somatostatin is involved the idea is striking whether somatostatin-receptor density in the cortex of cerebral hemispheres might be related to gender identity. |
2003-03-06 |
2023-08-12 |
human |
| Robert Pichler, Wilhelmine Maschek, Carmen Crespillo, Isabel Esteva, Federico Sorigue. Is there a gender difference of somatostatin-receptor density in the human brain? Neuro endocrinology letters. vol 23. issue 5-6. 2003-03-06. PMID:12500167. |
this shows a tendency in males for relatively augmented uptake indicating higher somatostatin receptor density in temporal and frontal cerebral cortex. |
2003-03-06 |
2023-08-12 |
human |
| Lilian Puebla, Eduardo Arilla-Ferreir. Modulation of somatostatin receptors, somatostatin content and Gi proteins by substance P in the rat frontoparietal cortex and hippocampus. Journal of neurochemistry. vol 84. issue 1. 2003-01-23. PMID:12485411. |
modulation of somatostatin receptors, somatostatin content and gi proteins by substance p in the rat frontoparietal cortex and hippocampus. |
2003-01-23 |
2023-08-12 |
rat |
| L Puebla, E Arill. alpha-Fluoromethylhistidine influences somatostatin content, binding and inhibition of adenylyl cyclase activity in the rat frontoparietal cortex. Regulatory peptides. vol 59. issue 1. 2003-01-16. PMID:12506421. |
alpha-fluoromethylhistidine influences somatostatin content, binding and inhibition of adenylyl cyclase activity in the rat frontoparietal cortex. |
2003-01-16 |
2023-08-12 |
rat |