| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Biggins, J R McDermott, A I Smith, J M Candy, R H Perry, D E Bateman, J A Edwardso. Chromatographic characterization of neuropeptides in post mortem human brain. Journal of the neurological sciences. vol 66. issue 1. 1985-02-22. PMID:6084049. |
reverse phase high performance liquid chromatography was used to establish the immunoreactive species of five neuropeptides (thyrotropin-releasing hormone, luteinising hormone-releasing hormone, neurotensin, substance-p and somatostatin) in three areas of post mortem human brain--the hypothalamus, amygdala and cortex. |
1985-02-22 |
2023-08-12 |
human |
| A Morel, P Gluschankof, S Gomez, V Fafeur, P Cohe. Characterization of a somatostatin-28 containing the (Tyr-7, Gly-10) derivative of somatostatin-14: a terminal active product of prosomatostatin II processing in anglerfish pancreatic islets. Proceedings of the National Academy of Sciences of the United States of America. vol 81. issue 22. 1985-01-02. PMID:6150481. |
exposure of this somatostatin-28 species to an endopeptidase activity from the rat brain cortex generates a peptide immunologically related to somatostatin and undistinguishable from synthetic (tyr-7, gly-10) somatostatin-14 ii by hplc. |
1985-01-02 |
2023-08-12 |
rat |
| P Gluschankof, A Morel, S Gomez, P Nicolas, C Fahy, P Cohe. Enzymes processing somatostatin precursors: an Arg-Lys esteropeptidase from the rat brain cortex converting somatostatin-28 into somatostatin-14. Proceedings of the National Academy of Sciences of the United States of America. vol 81. issue 21. 1984-12-19. PMID:6149550. |
enzymes processing somatostatin precursors: an arg-lys esteropeptidase from the rat brain cortex converting somatostatin-28 into somatostatin-14. |
1984-12-19 |
2023-08-12 |
rat |
| S H Hendry, E G Jones, P C Emso. Morphology, distribution, and synaptic relations of somatostatin- and neuropeptide Y-immunoreactive neurons in rat and monkey neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 4. issue 10. 1984-11-28. PMID:6149273. |
neurons in the monkey and rat cerebral cortex immunoreactive for somatostatin tetradecapeptide (srif) and for neuropeptide y (npy) were examined in the light and electron microscope. |
1984-11-28 |
2023-08-12 |
rat |
| J C Reub. Evidence for two somatostatin-14 receptor types in rat brain cortex. Neuroscience letters. vol 49. issue 3. 1984-11-26. PMID:6149498. |
this suggests the presence in the cortex of more than one population of somatostatin receptors. |
1984-11-26 |
2023-08-12 |
rat |
| R J Joynt, T H McNeil. Neuropeptides in aging and dementia. Peptides. vol 5 Suppl 1. 1984-11-09. PMID:6148737. |
this study examined the morphology of two neurochemically-defined neuronal populations (i.e., neurophysin, somatostatin) in the cortex and hypothalamus to determine if structural changes in these neuropeptide systems associated with advancing age are similar to those seen with sdat. |
1984-11-09 |
2023-08-12 |
Not clear |
| A Weindl, J Triepel, G Kuchlin. Somatostatin in the brain of the turtle Testudo hermanni Gmelin. An immunohistochemical mapping study. Peptides. vol 5 Suppl 1. 1984-11-09. PMID:6148740. |
within the telencephalon, somatostatin perikarya are present in the anterior olfactory nucleus, in the medial, dorsomedial and dorsal cortex, in the pallial thickening, in the piriform cortex, paleostriatum augmentatum, in the dorsoventricular ridge, core nucleus of the dorsoventricular ridge, in area c and d, and in the amygdala. |
1984-11-09 |
2023-08-12 |
Not clear |
| A Weindl, J Triepel, G Kuchlin. Somatostatin in the brain of the turtle Testudo hermanni Gmelin. An immunohistochemical mapping study. Peptides. vol 5 Suppl 1. 1984-11-09. PMID:6148740. |
in the telencephalon, dense aggregations of somatostatin fibres are present in the anterior olfactory nucleus, in the pallial thickening, in the parahippocampal gyrus, cortex medialis, dorsomedialis, dorsalis and piriformis, in the dorsal ventricular ridge, paleostriatum augmentatum, area c and d, in the septum, nu. |
1984-11-09 |
2023-08-12 |
Not clear |
| D E Schmechel, B G Vickrey, D Fitzpatrick, R P Eld. GABAergic neurons of mammalian cerebral cortex: widespread subclass defined by somatostatin content. Neuroscience letters. vol 47. issue 3. 1984-10-15. PMID:6147798. |
gabaergic neurons of mammalian cerebral cortex: widespread subclass defined by somatostatin content. |
1984-10-15 |
2023-08-12 |
rat |
| D E Schmechel, B G Vickrey, D Fitzpatrick, R P Eld. GABAergic neurons of mammalian cerebral cortex: widespread subclass defined by somatostatin content. Neuroscience letters. vol 47. issue 3. 1984-10-15. PMID:6147798. |
somatostatin content may define a widespread subclass of gabaergic neurons in mammalian cerebral cortex. |
1984-10-15 |
2023-08-12 |
rat |
| J M Allen, I N Ferrier, G W Roberts, A J Cross, T E Adrian, T J Crow, S R Bloo. Elevation of neuropeptide Y (NPY) in substantia innominata in Alzheimer's type dementia. Journal of the neurological sciences. vol 64. issue 3. 1984-09-28. PMID:6147394. |
in contrast, although cortical concentrations of somatostatin were reduced in atd, no change was found in the concentrations of npy in the 4 regions of cerebral cortex and the remaining subcortical areas examined. |
1984-09-28 |
2023-08-12 |
Not clear |
| C Sakamoto, I D Goldfine, J A William. The somatostatin receptor on isolated pancreatic acinar cell plasma membranes. Identification of subunit structure and direct regulation by cholecystokinin. The Journal of biological chemistry. vol 259. issue 15. 1984-09-17. PMID:6146617. |
in contrast cerebral cortex membranes, which also possess a somatostatin receptor, were not regulated by cck. |
1984-09-17 |
2023-08-12 |
rat |
| M N Rossor, L L Iversen, G P Reynolds, C Q Mountjoy, M Rot. Neurochemical characteristics of early and late onset types of Alzheimer's disease. British medical journal (Clinical research ed.). vol 288. issue 6422. 1984-05-14. PMID:6142750. |
the alzheimer group exhibited noticeably reduced activity of the cholinergic marker enzyme choline acetyltransferase in the cerebral cortex, but cortical concentrations of noradrenaline, gamma-aminobutyric acid, and somatostatin were also significantly reduced. |
1984-05-14 |
2023-08-12 |
human |
| G W Roberts, P L Woodhams, J M Polak, T J Cro. Distribution of neuropeptides in the limbic system of the rat: the hippocampus. Neuroscience. vol 11. issue 1. 1984-05-02. PMID:6200800. |
peptide-containing fibres were identified entering or leaving the hippocampus in three ways, via (i) the fornix (all six peptides), (ii) the dorsal subiculum (neurotensin-positive fibres projecting to the cingulate cortex: somatostatin, vasoactive intestinal polypeptide, and cholecystokinin-octapeptide present in fibres running between the dorsal subiculum and occipito-parietal cortex) and (iii) the ventral subiculum (vasoactive intestinal polypeptide, cholecystokinin-octapeptide and somatostatin in fibres running between entorhinal cortex and hippocampus, and all six peptides in fibres crossing the amygdalo-hippocampal border). |
1984-05-02 |
2023-08-12 |
rat |
| K T Borer, B Shapiro, A I Vini. A role for somatostatin in the control of hamster growth. Brain research bulletin. vol 11. issue 6. 1984-03-08. PMID:6140995. |
concentrations of somatostatin-like immunoreactivity (srif-li) were measured in cerebral cortex, hippocampus, septum-poa, median eminence, gastric antrum, fundus and pancreas in adult female hamsters to determine whether changes in somatostatin could be related to increased growth hormone (gh) secretion and somatic growth that follow bilateral transections of hippocampus (n = 18; 17 controls). |
1984-03-08 |
2023-08-12 |
cat |
| J Epelbaum, M Ruberg, E Moyse, F Javoy-Agid, B Dubois, Y Agi. Somatostatin and dementia in Parkinson's disease. Brain research. vol 278. issue 1-2. 1984-01-27. PMID:6139152. |
the concentrations of somatostatin in the cortex, hippocampus and caudate nucleus of subjects with parkinson's disease were determined by radioimmunoassay. |
1984-01-27 |
2023-08-12 |
human |
| M F Bear, F F Ebne. Somatostatin-like immunoreactivity in the forebrain of Pseudemys turtles. Neuroscience. vol 9. issue 2. 1983-09-23. PMID:6192360. |
we speculate that somatostatin plays a similar role in the normal function of all types of cortex and suggest that turtle cortex may provide a useful model for the study of this cortical neuropeptide. |
1983-09-23 |
2023-08-12 |
Not clear |
| A Enjalbert, R Rasolonjanahary, E Moyse, C Kordon, J Epelbau. Guanine nucleotide sensitivity of [125I]-Iodo NTyr somatostatin binding in rat adenohypophysis and cerebral cortex. Endocrinology. vol 113. issue 2. 1983-09-09. PMID:6135601. |
guanine nucleotide sensitivity of [125i]-iodo ntyr somatostatin binding in rat adenohypophysis and cerebral cortex. |
1983-09-09 |
2023-08-12 |
rat |
| A Enjalbert, R Rasolonjanahary, E Moyse, C Kordon, J Epelbau. Guanine nucleotide sensitivity of [125I]-Iodo NTyr somatostatin binding in rat adenohypophysis and cerebral cortex. Endocrinology. vol 113. issue 2. 1983-09-09. PMID:6135601. |
these results, showing the nucleotide sensitivity of [125i]-iodo-ntyr somatostatin binding in pituitary and cerebral cortex, are compatible with a coupling of somatostatin receptors with adenylate cyclase. |
1983-09-09 |
2023-08-12 |
rat |
| L A Dokas, H Zwiers, D H Coy, W H Gispe. Somatostatin and analogs inhibit endogenous synaptic plasma membrane protein phosphorylation in vitro. European journal of pharmacology. vol 88. issue 2-3. 1983-07-08. PMID:6133768. |
inhibition of b-50 protein phosphorylation in the presence of [d-trp8]somatostatin was most prominent in spm preparations from the hippocampus and amygdala, with lesser degrees of inhibition seen in the cortex and hypothalamus. |
1983-07-08 |
2023-08-12 |
rat |