| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C Reubi, R Maure. Autoradiographic mapping of somatostatin receptors in the rat central nervous system and pituitary. Neuroscience. vol 15. issue 4. 1985-11-08. PMID:2864657. |
receptors are particularly concentrated in the deeper layers of the cerebral cortex and large areas of the limbic system are rich in somatostatin receptors, in particular the hippocampus (ca1, ca2, dentate gyrus), most amygdaloid nuclei, the medial habenula and the septum. |
1985-11-08 |
2023-08-11 |
rat |
| P Cohen, A Morel, P Gluschankof, S Gomez, P Nicola. Proteolytic events in the post-translational processing of somatostatin precursors from rat brain cortex and anglerfish pancreatic islets. Advances in experimental medicine and biology. vol 188. 1985-09-30. PMID:2863926. |
proteolytic events in the post-translational processing of somatostatin precursors from rat brain cortex and anglerfish pancreatic islets. |
1985-09-30 |
2023-08-11 |
rat |
| R Elde, O Johansson, T Hokfel. Immunocytochemical studies of somatostatin neurons in brain. Advances in experimental medicine and biology. vol 188. 1985-09-30. PMID:2863929. |
for example, somatostatin is found within neurons ranging in location from the cerebral cortex to primary sensory neurons to enteric neurons within the gut wall. |
1985-09-30 |
2023-08-11 |
Not clear |
| R Robbin. Somatostatin and the cerebral cortex. Advances in experimental medicine and biology. vol 188. 1985-09-30. PMID:2863932. |
somatostatin and the cerebral cortex. |
1985-09-30 |
2023-08-11 |
human |
| R E Catalán, A M Martínez, M D Aragonés, J E Godo. Actions of somatostatin on lipid metabolism in mouse cerebral cortex slices. Neuroscience research. vol 2. issue 3. 1985-09-11. PMID:2862617. |
actions of somatostatin on lipid metabolism in mouse cerebral cortex slices. |
1985-09-11 |
2023-08-11 |
mouse |
| R E Catalán, A M Martínez, M D Aragonés, J E Godo. Actions of somatostatin on lipid metabolism in mouse cerebral cortex slices. Neuroscience research. vol 2. issue 3. 1985-09-11. PMID:2862617. |
cerebral cortex slices from mice were used to investigate the variations of lipid metabolism by somatostatin. |
1985-09-11 |
2023-08-11 |
mouse |
| R E Catalán, A M Martínez, M D Aragonés, J E Godo. Actions of somatostatin on lipid metabolism in mouse cerebral cortex slices. Neuroscience research. vol 2. issue 3. 1985-09-11. PMID:2862617. |
these results add more information about the effects of somatostatin in cerebral cortex. |
1985-09-11 |
2023-08-11 |
mouse |
| D L Niehoff, A W Mudg. Somatostatin alters beta-adrenergic receptor-effector coupling in cultured rat astrocytes. The EMBO journal. vol 4. issue 2. 1985-09-04. PMID:2862027. |
the neuropeptide somatostatin potentiates beta-adrenergic receptor-mediated camp formation in astrocytes derived from neonatal rat cortex but does not affect camp levels by itself. |
1985-09-04 |
2023-08-11 |
rat |
| J M Allen, A J Cross, T J Crow, F Javoy-Agid, Y Agid, S R Bloo. Dissociation of neuropeptide Y and somatostatin in Parkinson's disease. Brain research. vol 337. issue 1. 1985-08-21. PMID:2860955. |
the concentration of neuropeptide y has been determined in the cortex and hippocampus of subjects with parkinson's disease and compared to changes of activity of dopamine beta-hydroxylase and concentration of somatostatin. |
1985-08-21 |
2023-08-11 |
human |
| J M Allen, A J Cross, T J Crow, F Javoy-Agid, Y Agid, S R Bloo. Dissociation of neuropeptide Y and somatostatin in Parkinson's disease. Brain research. vol 337. issue 1. 1985-08-21. PMID:2860955. |
despite a marked reduction in the concentration of somatostatin in the severely demented subject, in both cortex and hippocampus, no significant change in concentration of npy was found in either region. |
1985-08-21 |
2023-08-11 |
human |
| J M Allen, A J Cross, T J Crow, F Javoy-Agid, Y Agid, S R Bloo. Dissociation of neuropeptide Y and somatostatin in Parkinson's disease. Brain research. vol 337. issue 1. 1985-08-21. PMID:2860955. |
this finding therefore suggests that the majority of npy within the cortex is independent of somatostatin. |
1985-08-21 |
2023-08-11 |
human |
| E Taber-Pierce, E Lichentenstein, S C Feldma. The somatostatin systems of the guinea-pig brainstem. Neuroscience. vol 15. issue 1. 1985-08-21. PMID:2861583. |
of the nuclei related to the auditory system, somatostatin neurons were present only in the dorsal and ventral trapezoid nuclei and in the cortex of the inferior colliculus. |
1985-08-21 |
2023-08-11 |
rat |
| M F Beal, M F Mazurek, V T Tran, G Chattha, E D Bird, J B Marti. Reduced numbers of somatostatin receptors in the cerebral cortex in Alzheimer's disease. Science (New York, N.Y.). vol 229. issue 4710. 1985-08-09. PMID:2861661. |
reduced numbers of somatostatin receptors in the cerebral cortex in alzheimer's disease. |
1985-08-09 |
2023-08-11 |
Not clear |
| R Maurer, J C Reub. Brain somatostatin receptor subpopulation visualized by autoradiography. Brain research. vol 333. issue 1. 1985-07-02. PMID:2986771. |
although the cyclic octapeptide ligands label the majority of the regions labeled with [125i-tyr11]somatostatin, in the cortex and hippocampus only a subpopulation of somatostatin receptors is labeled. |
1985-07-02 |
2023-08-11 |
rat |
| H Chneiweiss, J Glowinski, J Prémon. Modulation by monoamines of somatostatin-sensitive adenylate cyclase on neuronal and glial cells from the mouse brain in primary cultures. Journal of neurochemistry. vol 44. issue 6. 1985-06-18. PMID:2859357. |
primary cultures of mouse embryonic neuronal or glial cells from the cerebral cortex, striatum, and mesencephalon were used to identify and determine the cellular localization of somatostatin receptors coupled to an adenylate cyclase. |
1985-06-18 |
2023-08-11 |
mouse |
| H Chneiweiss, J Glowinski, J Prémon. Modulation by monoamines of somatostatin-sensitive adenylate cyclase on neuronal and glial cells from the mouse brain in primary cultures. Journal of neurochemistry. vol 44. issue 6. 1985-06-18. PMID:2859357. |
finally, somatostatin was shown to inhibit adenylate cyclase activity following its activation by (-)-isoproterenol on glial crude membranes of the striatum and the mesencephalon but not on those of the cerebral cortex. |
1985-06-18 |
2023-08-11 |
mouse |
| C B Srikant, Y C Pate. Somatostatin receptors in the rat adrenal cortex: characterization and comparison with brain and pituitary receptors. Endocrinology. vol 116. issue 5. 1985-05-30. PMID:2859190. |
somatostatin receptors in the rat adrenal cortex: characterization and comparison with brain and pituitary receptors. |
1985-05-30 |
2023-08-11 |
rat |
| G W Roberts, T J Crow, J M Pola. Location of neuronal tangles in somatostatin neurones in Alzheimer's disease. Nature. vol 314. issue 6006. 1985-04-19. PMID:2858057. |
neurochemical investigations have established loss of the cholinergic and aminergic projections to the cerebral cortex and a loss of the content of somatostatin, with preservation of cholecystokinin and vasoactive intestinal polypeptide, neuropeptides also located in cells intrinsic to the cortex. |
1985-04-19 |
2023-08-11 |
Not clear |
| H Chneiweiss, J Glowinski, J Prémon. Vasoactive intestinal polypeptide receptors linked to an adenylate cyclase, and their relationship with biogenic amine- and somatostatin-sensitive adenylate cyclases on central neuronal and glial cells in primary cultures. Journal of neurochemistry. vol 44. issue 3. 1985-03-25. PMID:2857767. |
in addition, vip modified the characteristics of the somatostatin inhibitory effect on adenylate cyclase activity of neuronal membranes from the cerebral cortex and striatum but not from those of the mesencephalon. |
1985-03-25 |
2023-08-11 |
mouse |
| T Higuchi, K R Shah, G S Sikand, M West, H G Friese. Changes in immunoreactive somatostatin in brain following lidocaine-induced kindling in rat. Neuropharmacology. vol 23. issue 11. 1985-03-25. PMID:6152021. |
immunoreactive somatostatin was significantly greater than in controls in the amygdala (56%; p less than 0.02), entorhinal + piriform cortex (50%; p less than 0.05) and hypothalamus (29%; p less than 0.02). |
1985-03-25 |
2023-08-12 |
rat |