| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163885. |
four dermal fibroblast cell strains were established in cell culture from four human postburn hypertrophic scar tissues with the use of normal dermal fibroblasts from the same patients as controls. |
2012-10-02 |
2023-08-12 |
human |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163885. |
the level of fibronectin messenger rna expression decreased from 17.2% to 69% in hypertrophic scar fibroblasts and 47% to 83.7% in normal fibroblasts relative to that of untreated control values. |
2012-10-02 |
2023-08-12 |
human |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163885. |
although this decrease was less pronounced in normal fibroblasts than in hypertrophic scar fibroblasts, this reduction was significant in both interferon alfa-2b treated hypertrophic scar fibroblasts (6.39 +/- 0.71 versus 2.88 +/- 0.9, n = 4, p < 0.05) and normal cells compared with untreated controls (5.47 +/- 0.89 versus 3.64 +/- 0.99, n = 4, p < 0.05) as assessed with student's paired t test. |
2012-10-02 |
2023-08-12 |
human |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163885. |
rehybridization of the rna blot prepared from interferon alfa-2b treated and untreated hypertrophic scar fibroblasts with a complementary dna for the tissue inhibitor of metalloproteinase type 2 gelatinase inhibitor showed no significant changes in abundance of this transcript. |
2012-10-02 |
2023-08-12 |
human |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163885. |
a dot blot analysis of total rna extracted from these tissues was carried out to compare the expression of fibronectin messenger rna between human hypertrophic scar tissues and normal dermis obtained from the same patients. |
2012-10-02 |
2023-08-12 |
human |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163885. |
when the ratio of fibronectin to tissue inhibitor or metalloproteinase type 2 messenger rna expression for each hypertrophic scar tissue was compared with its normal control, this ratio was fourfold higher in human hypertrophic scar tissues relative to normal controls. |
2012-10-02 |
2023-08-12 |
human |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163885. |
in contrast, the expression of this message in cultured hypertrophic scar fibroblasts was not significantly different from that in normal fibroblasts. |
2012-10-02 |
2023-08-12 |
human |
| J C Sible, E Eriksson, S P Smith, N Smit. Fibronectin gene expression differs in normal and abnormal human wound healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 2. issue 1. 2012-10-02. PMID:17168907. |
this study compared the content of fibronectin messenger rna and rates of fibronectin protein biosynthesis in fibroblasts derived from normal skin, normal scar, keloid, and hypertrophic scar. |
2012-10-02 |
2023-08-12 |
human |
| J C Sible, E Eriksson, S P Smith, N Smit. Fibronectin gene expression differs in normal and abnormal human wound healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 2. issue 1. 2012-10-02. PMID:17168907. |
thus, fibroblasts from keloids and hypertrophic scars overexpressed fibronectin in vivo relative to normal skin and normal scar and retain this characteristic in vitro relative to normal skin. |
2012-10-02 |
2023-08-12 |
human |
| S S Savan. Facial dermabrasion in acne scars and genodermatoses-A study of 65 patients. Indian journal of dermatology, venereology and leprology. vol 66. issue 2. 2012-10-02. PMID:20877033. |
complications encountered were small deep scars 8, recurrence of adenoma sebaceum 3, gouging 2, secondary infection 2, oval large atrophic hypo-depigmented scar i and hypertrophic linear scar 1. |
2012-10-02 |
2023-08-12 |
Not clear |
| Ling Tao, Jianyi Liu, Zhe Li, Xia Dai, Shirong L. Role of the JAK-STAT pathway in proliferation and differentiation of human hypertrophic scar fibroblasts induced by connective tissue growth factor. Molecular medicine reports. vol 3. issue 6. 2012-10-02. PMID:21472337. |
role of the jak-stat pathway in proliferation and differentiation of human hypertrophic scar fibroblasts induced by connective tissue growth factor. |
2012-10-02 |
2023-08-12 |
human |
| Ling Tao, Jianyi Liu, Zhe Li, Xia Dai, Shirong L. Role of the JAK-STAT pathway in proliferation and differentiation of human hypertrophic scar fibroblasts induced by connective tissue growth factor. Molecular medicine reports. vol 3. issue 6. 2012-10-02. PMID:21472337. |
the aim of this study was to investigate whether the jak-stat pathway participates in the processes of proliferation and differentiation induced by connective tissue growth factor (ctgf) in human hypertrophic scar fibroblasts (hhsf). |
2012-10-02 |
2023-08-12 |
human |
| C W Kischer, J Pindu. Effects of platelet derived growth factor (PDGF) on fibronectin (FN) production by human skin and scar fibroblasts. Cytotechnology. vol 3. issue 3. 2012-10-02. PMID:22358773. |
each hypertrophic scar, keloid and normal adjacent skin, with one exception, showed typical histologic findings confirming the clinical diagnosis. |
2012-10-02 |
2023-08-12 |
human |
| C W Kischer, J Pindu. Effects of platelet derived growth factor (PDGF) on fibronectin (FN) production by human skin and scar fibroblasts. Cytotechnology. vol 3. issue 3. 2012-10-02. PMID:22358773. |
however, no significant difference was observed between the other keloid and as, nor between the other hypertrophic scar and ds. |
2012-10-02 |
2023-08-12 |
human |
| Ali M Soltani, Cameron S Francis, Arash Motamed, Ashley L Karatsonyi, Jeffrey A Hammoudeh, Pedro A Sanchez-Lara, John F Reinisch, Mark M Urat. Hypertrophic scarring in cleft lip repair: a comparison of incidence among ethnic groups. Clinical epidemiology. vol 4. 2012-10-02. PMID:22879780. |
although hypertrophic scar (hts) formation following cleft lip repair is relatively common, published rates vary widely, from 1% to nearly 50%. |
2012-10-02 |
2023-08-12 |
Not clear |
| Brooke L Farrugia, Daniel J Keddie, Graeme A George, Emily C Lynam, Michael A Brook, Zee Upton, Tim R Dargavill. An investigation into the effect of amphiphilic siloxane oligomers on dermal fibroblasts. Journal of biomedical materials research. Part A. vol 100. issue 7. 2012-10-01. PMID:22581620. |
these results suggest the possible use of the peg-pdms-peg block co-oligomers as an alternative to silicone gels for hypertrophic scar remediation. |
2012-10-01 |
2023-08-12 |
human |
| A Korekawa, H Nakano, Y Toyomaki, N Takiyoshi, D Rokunohe, E Akasaka, K Nakajima, D Sawamur. Buschke-Ollendorff syndrome associated with hypertrophic scar formation: a possible role for LEMD3 mutation. The British journal of dermatology. vol 166. issue 4. 2012-09-20. PMID:21985280. |
buschke-ollendorff syndrome associated with hypertrophic scar formation: a possible role for lemd3 mutation. |
2012-09-20 |
2023-08-12 |
Not clear |
| Chi-yu Ji. [Awareness of present status of study on hypertrophic scar]. Zhonghua yi xue za zhi. vol 91. issue 37. 2012-09-20. PMID:22321920. |
[awareness of present status of study on hypertrophic scar]. |
2012-09-20 |
2023-08-12 |
Not clear |
| Kunwar S S Bhatia, Edmund H Y Yuen, Carmen C M Cho, Cina S L Tong, Yolanda Y P Lee, Anil T Ahuj. A pilot study evaluating real-time shear wave ultrasound elastography of miscellaneous non-nodal neck masses in a routine head and neck ultrasound clinic. Ultrasound in medicine & biology. vol 38. issue 6. 2012-09-20. PMID:22502891. |
forty lesions were benign (9 lipomas, 8 lymphatic/venous vascular malformations, 7 thyroglossal duct cysts, 4 branchial cleft cysts, 4 abscesses/phlegmons, 3 neurogenic tumors and 1 each of paraganglioma, sebaceous cyst, pseudotumor, hypertrophic scar, ranula) and 6 were malignant (1 malignant fibrous histiocytoma, 2 primary squamous cell carcinomas and 3 intramuscular metastases [2 squamous cell carcinomas, 1 malignant melanoma]).median stiffness of malignant lesions (226.4 kpa, range 55.6 to 300.0) was higher than benign lesions (28.3 kpa, range 4.0 to 300.0) (p < 0.001). |
2012-09-20 |
2023-08-12 |
Not clear |
| Robert E Park, Laszlo Saghy, Erica S Zado, Cory M Tschabrunn, Francis E Marchlinsk. Influence of left ventricular hypertrophy on scar identification during bipolar voltage mapping. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. vol 34. issue 1. 2012-09-07. PMID:22170283. |
influence of left ventricular hypertrophy on scar identification during bipolar voltage mapping. |
2012-09-07 |
2023-08-12 |
Not clear |