| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhen Zhang, Yan Wo, Yixin Zhang, Danru Wang, Rong He, Huijin Chen, Daxiang Cu. In vitro study of ethosome penetration in human skin and hypertrophic scar tissue. Nanomedicine : nanotechnology, biology, and medicine. vol 8. issue 6. 2012-12-03. PMID:22033085. |
in vitro study of ethosome penetration in human skin and hypertrophic scar tissue. |
2012-12-03 |
2023-08-12 |
human |
| Zhen Zhang, Yan Wo, Yixin Zhang, Danru Wang, Rong He, Huijin Chen, Daxiang Cu. In vitro study of ethosome penetration in human skin and hypertrophic scar tissue. Nanomedicine : nanotechnology, biology, and medicine. vol 8. issue 6. 2012-12-03. PMID:22033085. |
the delivery of drugs from ethosomes in human hypertrophic scar (hs) and the mechanisms of action of ethosomes in human hs were investigated. |
2012-12-03 |
2023-08-12 |
human |
| Ahmet Metin Sanli, Hayri Kertmen, Erdal Resit Yilmaz, Zeki Sekerc. A retained wood penetrating the superior orbital fissure in a neurologically intact child. Turkish neurosurgery. vol 22. issue 3. 2012-11-29. PMID:22665017. |
on physical examination, the patient had only a hypertrophic scar on his medial side of left upper eyelid at the admission. |
2012-11-29 |
2023-08-12 |
Not clear |
| Manuel Mazo, Arantxa Cemborain, Juan José Gavira, Gloria Abizanda, Miriam Araña, Mayte Casado, Mario Soriano, Salomón Hernández, Cristina Moreno, Margarita Ecay, Edurne Albiasu, Miriam Belzunce, Josune Orbe, José Antonio Páramo, Juana Merino, Iván Peñuelas, José Manuel García Verdugo, Beatriz Pelacho, Felipe Prospe. Adipose stromal vascular fraction improves cardiac function in chronic myocardial infarction through differentiation and paracrine activity. Cell transplantation. vol 21. issue 5. 2012-11-01. PMID:22305117. |
svf induced a statistically significant long-lasting (3 months) improvement in cardiac function and tissue metabolism that was associated with increased revascularization and positive heart remodeling, with a significantly smaller infarct size, thicker infarct wall, lower scar fibrosis, and lower cardiac hypertrophy. |
2012-11-01 |
2023-08-12 |
rat |
| Mathias Tremp, Reto Wettstein, Wassim Raffoul, Dirk J Schaefer, Daniel F Kalbermatte. Secret scar free gracilis flap. Journal of reconstructive microsurgery. vol 28. issue 5. 2012-10-24. PMID:22588799. |
the mean scar length was 16 ± 3 cm and no hypertrophic scars were observed. |
2012-10-24 |
2023-08-12 |
Not clear |
| Serkan Erbatur, Yusuf Kenan Coban, Engin Nasuhi Aydı. Comparision of clinical and histopathological results of hyalomatrix usage in adult patients. International journal of burns and trauma. vol 2. issue 2. 2012-10-17. PMID:23071910. |
ha were used for treatment of hypertrophic scar (hs) or keloid (k) in 10 patients of the first group. |
2012-10-17 |
2023-08-12 |
Not clear |
| Zhibo Xiao, Guofan Q. Effects of botulinum toxin type a on collagen deposition in hypertrophic scars. Molecules (Basel, Switzerland). vol 17. issue 2. 2012-10-09. PMID:22354193. |
the rabbit hypertrophic scar model was used and eight rabbits were employed. |
2012-10-09 |
2023-08-12 |
rabbit |
| Zhibo Xiao, Guofan Q. Effects of botulinum toxin type a on collagen deposition in hypertrophic scars. Molecules (Basel, Switzerland). vol 17. issue 2. 2012-10-09. PMID:22354193. |
btxa was injected into the hypertrophic scar tissue of one ear; and the other ear in the same rabbit was the control without btxa injection. |
2012-10-09 |
2023-08-12 |
rabbit |
| Zhibo Xiao, Guofan Q. Effects of botulinum toxin type a on collagen deposition in hypertrophic scars. Molecules (Basel, Switzerland). vol 17. issue 2. 2012-10-09. PMID:22354193. |
this study used the rabbit ear model of hypertrophic scars to assess the effects of btxa on scar hypertrophy. |
2012-10-09 |
2023-08-12 |
rabbit |
| G Sudhagar, Monique Le blan. Conservative management of ulnar tunnel syndrome: secondary to excessive healing tissue; a rare complication after flexor tendon injury--a case report. Techniques in hand & upper extremity surgery. vol 16. issue 2. 2012-10-03. PMID:22627928. |
the patient was managed conservatively for his hypertrophic scar for 9 weeks. |
2012-10-03 |
2023-08-12 |
Not clear |
| D V Messadi, S Berg, K Sung-Cho, M Lesavoy, C N Bertolam. Autocrine transforming growth factor-beta(1) activity and glycosaminoglycan synthesis by human cutaneous scar fibroblasts. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 2. issue 4. 2012-10-02. PMID:17147647. |
replicate explants (n = 3) of fibroblasts each derived from normal skin, normal scar, or hypertrophic scar were studied by adding exogenous transforming growth factor-beta(1) at a concentration range of 0 to 10 ng/ml. |
2012-10-02 |
2023-08-12 |
human |
| D V Messadi, S Berg, K Sung-Cho, M Lesavoy, C N Bertolam. Autocrine transforming growth factor-beta(1) activity and glycosaminoglycan synthesis by human cutaneous scar fibroblasts. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 2. issue 4. 2012-10-02. PMID:17147647. |
transforming growth factor-beta(1) was found to cause a dose-dependent increase in glycosaminoglycan synthesis in hypertrophic scar and normal skin but not in normal scar fibroblasts in cell-mediated glycosaminoglycan synthesis; the reverse was observed in cell-free glycosaminoglycan synthesis, where transforming growth factor-beta(1) increased glycosaminoglycan synthesis in normal scar but not in normal skin or hypertrophic scar. |
2012-10-02 |
2023-08-12 |
human |
| D V Messadi, S Berg, K Sung-Cho, M Lesavoy, C N Bertolam. Autocrine transforming growth factor-beta(1) activity and glycosaminoglycan synthesis by human cutaneous scar fibroblasts. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 2. issue 4. 2012-10-02. PMID:17147647. |
most endogenous transforming growth factor-beta(1) existed in latent form for normal skin cells but in active form for normal scar and hypertrophic scar fibroblasts. |
2012-10-02 |
2023-08-12 |
human |
| K Sahara, A Kucukcelebi, F Ko, L Phillips, M Robso. Suppression of in vitro proliferative scar fibroblast contraction by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 1. 2012-10-02. PMID:17147705. |
we used fibroblast-populated collagen lattices to evaluate the effect of interferon on fibroblasts harvested from normal human skin, human keloid, and hypertrophic scar tissues. |
2012-10-02 |
2023-08-12 |
human |
| E E Tredget, Y J Shen, G Liu, N Forsyth, C Smith, A Robertson Harrop, P G Scott, A Ghahar. Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163884. |
regulation of collagen synthesis and messenger rna levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b. |
2012-10-02 |
2023-08-12 |
Not clear |
| E E Tredget, Y J Shen, G Liu, N Forsyth, C Smith, A Robertson Harrop, P G Scott, A Ghahar. Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163884. |
to investigate the potential beneficial role and mechanism of interferon alfa-2b in controlling excessive collagen production in hypertrophic scar, we measured dose response, time of onset, and duration of action in hypertrophic scar fibroblasts in vitro and compared them with those of site-matched normal fibroblasts obtained from four patients after thermal injury. |
2012-10-02 |
2023-08-12 |
Not clear |
| E E Tredget, Y J Shen, G Liu, N Forsyth, C Smith, A Robertson Harrop, P G Scott, A Ghahar. Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163884. |
interferon alfa-2b reduced collagen protein synthesis and type i messenger rna levels in both hypertrophic scar and normal fibroblasts after treatment, but these changes were apparent only after approximately 72 hours. |
2012-10-02 |
2023-08-12 |
Not clear |
| E E Tredget, Y J Shen, G Liu, N Forsyth, C Smith, A Robertson Harrop, P G Scott, A Ghahar. Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163884. |
significant reductions in collagen synthesis occurred in four pairs of normal and hypertrophic scar fibroblasts (p < 0.05), accompanied by significant reductions in type i (p < 0.05) but not type iii procollagen messenger rna. |
2012-10-02 |
2023-08-12 |
Not clear |
| E E Tredget, Y J Shen, G Liu, N Forsyth, C Smith, A Robertson Harrop, P G Scott, A Ghahar. Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163884. |
hypertrophic scar fibroblasts recovered completely from the effects of interferon alfa-2b on procollagen type i messenger rna within 48 hours of cessation of treatment in contrast to normal skin fibroblasts, in which the reduction in type i procollagen messenger rna by interferon alfa-2b persisted beyond 72 hours after treatment. |
2012-10-02 |
2023-08-12 |
Not clear |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa-2b. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 1. issue 3. 2012-10-02. PMID:17163885. |
in this report, we provide evidence that this cytokine also significantly decreases the expression of fibronectin messenger rna in human hypertrophic scar and normal dermal fibroblasts. |
2012-10-02 |
2023-08-12 |
human |