| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wang ZhiYong, Song Fei, Xu LianJu, Liu Yingkai, Qing Chun, Lu Shuliang, Wang XiQia. Endostar injection inhibits rabbit ear hypertrophic scar formation. The international journal of lower extremity wounds. vol 11. issue 4. 2013-06-04. PMID:23089964. |
the rabbit ear hypertrophic scar models were established 4 weeks postoperation and were treated with endostar injection; the control group was injected with saline, once a week, 3 times totally. |
2013-06-04 |
2023-08-12 |
rabbit |
| Wang ZhiYong, Song Fei, Xu LianJu, Liu Yingkai, Qing Chun, Lu Shuliang, Wang XiQia. Endostar injection inhibits rabbit ear hypertrophic scar formation. The international journal of lower extremity wounds. vol 11. issue 4. 2013-06-04. PMID:23089964. |
the results showed that the volume of the hypertrophic scar with endostar injection was greatly reduced compared with what was seen in the control group; meanwhile, he staining showed that the cell number decreased and collagen density became looser. |
2013-06-04 |
2023-08-12 |
rabbit |
| Wang ZhiYong, Song Fei, Xu LianJu, Liu Yingkai, Qing Chun, Lu Shuliang, Wang XiQia. Endostar injection inhibits rabbit ear hypertrophic scar formation. The international journal of lower extremity wounds. vol 11. issue 4. 2013-06-04. PMID:23089964. |
in conclusion, the endostar is effective for hypertrophic scar inhibition and could be a potential tool to treat scars. |
2013-06-04 |
2023-08-12 |
rabbit |
| Ravi Kumar Chittoria, Tirupathi Rao Pad. A prospective, randomized, placebo controlled, double blind study of silicone gel in prevention of hypertrophic scar at donor site of skin grafting. Journal of cutaneous and aesthetic surgery. vol 6. issue 1. 2013-06-03. PMID:23723598. |
a prospective, randomized, placebo controlled, double blind study of silicone gel in prevention of hypertrophic scar at donor site of skin grafting. |
2013-06-03 |
2023-08-12 |
Not clear |
| Franck Duteille, Michel Rouif, Bruno Alfandari, Jean-Baptiste Andreoletti, Raphael Sinna, Bruno Laurent, Pierre Perro. Reduction of skin closure time without loss of healing quality: a multicenter prospective study in 100 patients comparing the use of Insorb absorbable staples with absorbable thread for dermal suture. Surgical innovation. vol 20. issue 1. 2013-05-31. PMID:22589018. |
ninety-five patients were reexamined by the surgeon after 1 year of follow-up to assess scar width, suppleness, inflammation, and hypertrophy. |
2013-05-31 |
2023-08-12 |
Not clear |
| Tara Lynn Stewart, Brandon Ball, Paul J Schembri, Keijiro Hori, Jie Ding, Heather A Shankowsky, Edward E Tredge. The use of laser Doppler imaging as a predictor of burn depth and hypertrophic scar postburn injury. Journal of burn care & research : official publication of the American Burn Association. vol 33. issue 6. 2013-05-27. PMID:22955162. |
the use of laser doppler imaging as a predictor of burn depth and hypertrophic scar postburn injury. |
2013-05-27 |
2023-08-12 |
Not clear |
| J Q Li, C W P Li-Tsang, Y P Huang, Y Chen, Y P Zhen. Detection of changes of scar thickness under mechanical loading using ultrasonic measurement. Burns : journal of the International Society for Burn Injuries. vol 39. issue 1. 2013-05-22. PMID:22763366. |
the intervention of pressure therapy on management of hypertrophic scar (hs) after burn is based on the theoretical assumption that the mechanical force added onto the scar tissue will reduce the growth of myofibroblasts which create the collagen clusters and the interstitial space, and to realign fibrous tissues, thus reducing the thickness of hs. |
2013-05-22 |
2023-08-12 |
human |
| Dong Won Lee, Sae Kwang Ku, Hyuk Jun Cho, Jeong Hwan Kim, Tran Tuan Hiep, Sang Duk Han, Bo Gyun Kim, Min Kyung Kang, Eui Seon Do, Joon Ho Jun, Sun Woo Jang, Mi-Won Son, Young Taek Sohn, Han-Gon Choi, Chul Soon Yong, Jong Oh Ki. Effects of Noscarna™ on hypertrophic scarring in the rabbit ear model: histopathological aspects. Archives of pharmacal research. vol 35. issue 11. 2013-05-13. PMID:23212642. |
after 4-week application of silicone-based gel containing allantoin, dexpanthenol and heparin (noscarna™) to scars in a rabbit ear model of hypertrophic scarring, significant improvements in hypertrophic scar healing and a great loss of skin pigment were observed compared to the non-treated control, base or silicone control-treated scars. |
2013-05-13 |
2023-08-12 |
rabbit |
| Dong Won Lee, Sae Kwang Ku, Hyuk Jun Cho, Jeong Hwan Kim, Tran Tuan Hiep, Sang Duk Han, Bo Gyun Kim, Min Kyung Kang, Eui Seon Do, Joon Ho Jun, Sun Woo Jang, Mi-Won Son, Young Taek Sohn, Han-Gon Choi, Chul Soon Yong, Jong Oh Ki. Effects of Noscarna™ on hypertrophic scarring in the rabbit ear model: histopathological aspects. Archives of pharmacal research. vol 35. issue 11. 2013-05-13. PMID:23212642. |
furthermore, histological analysis of noscarna™-treated scars revealed a significant reduction in scar elevation index (sei), anterior skin and epithelial thicknesses, inflammatory cells, vessels, collagen disorganization and fibroblasts compared to all control hypertrophic scars. |
2013-05-13 |
2023-08-12 |
rabbit |
| Jiangting Zhu, Biao Cheng, Hongwei Liu, Jianbing Tang, Xiaofei Xiang, Yan Pen. [Expression of beta-endorphin in hypertrophic scar and its relationship with pruritus]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 26. issue 6. 2013-05-09. PMID:22792774. |
[expression of beta-endorphin in hypertrophic scar and its relationship with pruritus]. |
2013-05-09 |
2023-08-12 |
human |
| Jiangting Zhu, Biao Cheng, Hongwei Liu, Jianbing Tang, Xiaofei Xiang, Yan Pen. [Expression of beta-endorphin in hypertrophic scar and its relationship with pruritus]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 26. issue 6. 2013-05-09. PMID:22792774. |
to identify the effect of beta-endorphin in the development of paresthesia in hypertrophic scar by detecting the expression and content of beta-endorphin in human normal skin and hypertrophic scar. |
2013-05-09 |
2023-08-12 |
human |
| Nils Krueger, Neil S Sadic. New-generation radiofrequency technology. Cutis. vol 91. issue 1. 2013-04-09. PMID:23461058. |
it is used worldwide for cellulite reduction; acne scar revision; and treatment of hypertrophic scars and keloids, rosacea, and inflammatory acne in all skin types. |
2013-04-09 |
2023-08-12 |
Not clear |
| Yih Miin Liew, Robert A McLaughlin, Peijun Gong, Fiona M Wood, David D Sampso. In vivo assessment of human burn scars through automated quantification of vascularity using optical coherence tomography. Journal of biomedical optics. vol 18. issue 6. 2013-04-04. PMID:23174911. |
a substantial increase was observed in the measured density of vasculature in hypertrophic scar tissues (38%) when compared against normal, unscarred skin (22%). |
2013-04-04 |
2023-08-12 |
human |
| Makram Ziade, Sophie Domergue, Dominique Batifol, Riad Jreige, Mustapha Sebbane, Patrick Goudot, Jacques Yachou. Use of botulinum toxin type A to improve treatment of facial wounds: a prospective randomised study. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 66. issue 2. 2013-03-14. PMID:23102873. |
this accounts for scar widening as well as hypertrophic and hyperpigmented scars. |
2013-03-14 |
2023-08-12 |
Not clear |
| Leonarda J van den Broek, Frank B Niessen, Rik J Scheper, Susan Gibb. Development, validation and testing of a human tissue engineered hypertrophic scar model. ALTEX. vol 29. issue 4. 2013-03-12. PMID:23138509. |
development, validation and testing of a human tissue engineered hypertrophic scar model. |
2013-03-12 |
2023-08-12 |
human |
| Leonarda J van den Broek, Frank B Niessen, Rik J Scheper, Susan Gibb. Development, validation and testing of a human tissue engineered hypertrophic scar model. ALTEX. vol 29. issue 4. 2013-03-12. PMID:23138509. |
here we describe the development and validation of a tissue-engineered human hypertrophic scar (htscar) model based on reconstructed epidermis on a dermal matrix containing adipose derived mesenchymal stem cells (asc). |
2013-03-12 |
2023-08-12 |
human |
| Leonarda J van den Broek, Frank B Niessen, Rik J Scheper, Susan Gibb. Development, validation and testing of a human tissue engineered hypertrophic scar model. ALTEX. vol 29. issue 4. 2013-03-12. PMID:23138509. |
this animal-free hypertrophic scar model may provide an alternative model for mechanistic studies as well as a novel in vitro means to test anti-scar therapeutics, thereby reducing the use of animals. |
2013-03-12 |
2023-08-12 |
human |
| L K Branski, H O Rennekampff, P M Vog. [Keloid and hypertrophic scar treatment modalities. An update]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen. vol 83. issue 9. 2013-03-11. PMID:22968425. |
[keloid and hypertrophic scar treatment modalities. |
2013-03-11 |
2023-08-12 |
Not clear |
| Oneil G Bhalala, Liuliu Pan, Vibhu Sahni, Tammy L McGuire, Katherine Gruner, Warren G Tourtellotte, John A Kessle. microRNA-21 regulates astrocytic response following spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 50. 2013-02-27. PMID:23238710. |
astrogliosis following spinal cord injury (sci) involves an early hypertrophic response that serves to repair damaged blood-brain barrier and a subsequent hyperplastic response that results in a dense scar that impedes axon regeneration. |
2013-02-27 |
2023-08-12 |
mouse |
| Oneil G Bhalala, Liuliu Pan, Vibhu Sahni, Tammy L McGuire, Katherine Gruner, Warren G Tourtellotte, John A Kessle. microRNA-21 regulates astrocytic response following spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 50. 2013-02-27. PMID:23238710. |
these findings demonstrate a novel role for mir-21 in regulating astrocytic hypertrophy and glial scar progression after sci, and suggest mir-21 as a potential therapeutic target for manipulating gliosis and enhancing functional outcome. |
2013-02-27 |
2023-08-12 |
mouse |