| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Binbin Wang, Bingbing Fan, Qijun Dai, Xingguo Xu, Peipei Jiang, Lin Zhu, Haifeng Dai, Zhigang Yao, Zhongling Xu, Xiaojuan Li. Fascin-1 Contributes to Neuropathic Pain by Promoting Inflammation in Rat Spinal Cord. Neurochemical research. vol 43. issue 2. 2018-08-16. PMID:29052088. |
the increased fascin-1 widely expressed in drg, however, it localized predominantly in microglia, seldom in neuron, and hardly in astrocyte in the sc. |
2018-08-16 |
2023-08-13 |
rat |
| Tina Khorshid Ahmad, Ting Zhou, Khaled AlTaweel, Claudia Cortes, Ryan Lillico, Ted Martin Lakowski, Kiana Gozda, Michael Peter Namak. Experimental Autoimmune Encephalomyelitis (EAE)-Induced Elevated Expression of the E1 Isoform of Methyl CpG Binding Protein 2 (MeCP2E1): Implications in Multiple Sclerosis (MS)-Induced Neurological Disability and Associated Myelin Damage. International journal of molecular sciences. vol 18. issue 6. 2018-04-02. PMID:28604632. |
however, our results demonstrate that baseline protein expression ratios between the mecp2e1 versus mecp2e2 isoforms in the sc are higher than those identified within the dorsal root ganglia (drg). |
2018-04-02 |
2023-08-13 |
Not clear |
| Tina Khorshid Ahmad, Ting Zhou, Khaled AlTaweel, Claudia Cortes, Ryan Lillico, Ted Martin Lakowski, Kiana Gozda, Michael Peter Namak. Experimental Autoimmune Encephalomyelitis (EAE)-Induced Elevated Expression of the E1 Isoform of Methyl CpG Binding Protein 2 (MeCP2E1): Implications in Multiple Sclerosis (MS)-Induced Neurological Disability and Associated Myelin Damage. International journal of molecular sciences. vol 18. issue 6. 2018-04-02. PMID:28604632. |
thus, the drg represents a more conducive environment than that of the sc for bdnf production and transport to the cns to assist in myelin repair. |
2018-04-02 |
2023-08-13 |
Not clear |
| Tina Khorshid Ahmad, Ting Zhou, Khaled AlTaweel, Claudia Cortes, Ryan Lillico, Ted Martin Lakowski, Kiana Gozda, Michael Peter Namak. Experimental Autoimmune Encephalomyelitis (EAE)-Induced Elevated Expression of the E1 Isoform of Methyl CpG Binding Protein 2 (MeCP2E1): Implications in Multiple Sclerosis (MS)-Induced Neurological Disability and Associated Myelin Damage. International journal of molecular sciences. vol 18. issue 6. 2018-04-02. PMID:28604632. |
thus, the lower e1/e2 ratios in the drg, allow the drg to serve as a weak secondary compensatory mechanism for enhanced production and delivery of bdnf to the sc to try to assist in myelin repair. |
2018-04-02 |
2023-08-13 |
Not clear |
| Aisha Siddiqah Ahmed, Mahmood Ahmed, Jian Li, Harvest F Gu, Georgy Bakalkin, André Stark, Helena Erlandsson Harri. Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis. International journal of rheumatic diseases. vol 20. issue 1. 2018-03-19. PMID:24702728. |
our present study aims to study the effects of mg132 on molecular changes in the dorsal root ganglia (drg) and in the spinal cord (sc) using the same animal model. |
2018-03-19 |
2023-08-13 |
rat |
| Arnulf H Koeppen, Alyssa B Becker, Jiang Qian, Paul J Feuste. Friedreich Ataxia: Hypoplasia of Spinal Cord and Dorsal Root Ganglia. Journal of neuropathology and experimental neurology. vol 76. issue 2. 2017-06-22. PMID:28082326. |
here, we measured cross-sectional areas of the mid-thoracic spinal cord (sc) and neuronal sizes in lumbosacral drg of 24 genetically confirmed fa cases. |
2017-06-22 |
2023-08-13 |
Not clear |
| Arnulf H Koeppen, Alyssa B Becker, Jiang Qian, Paul J Feuste. Friedreich Ataxia: Hypoplasia of Spinal Cord and Dorsal Root Ganglia. Journal of neuropathology and experimental neurology. vol 76. issue 2. 2017-06-22. PMID:28082326. |
mean thoracic sc areas in fa (24.17 mm2) were significantly smaller than those in 12 normal controls (37.5 mm2); drg neuron perikarya in fa (1362 µm2) were also significantly smaller than normal (2004 µm2). |
2017-06-22 |
2023-08-13 |
Not clear |
| Arnulf H Koeppen, Alyssa B Becker, Jiang Qian, Paul J Feuste. Friedreich Ataxia: Hypoplasia of Spinal Cord and Dorsal Root Ganglia. Journal of neuropathology and experimental neurology. vol 76. issue 2. 2017-06-22. PMID:28082326. |
drg neuron sizes were not correlated with sc areas. |
2017-06-22 |
2023-08-13 |
Not clear |
| Arnulf H Koeppen, Alyssa B Becker, Jiang Qian, Paul J Feuste. Friedreich Ataxia: Hypoplasia of Spinal Cord and Dorsal Root Ganglia. Journal of neuropathology and experimental neurology. vol 76. issue 2. 2017-06-22. PMID:28082326. |
we conclude that smaller sc areas and lack of large drg neurons indicate hypoplasia rather than atrophy in fa. |
2017-06-22 |
2023-08-13 |
Not clear |
| Monchanok Choowanthanapakorn, Kung-Wen Lu, Jun Yang, Ching-Liang Hsieh, Yi-Wen Li. Targeting TRPV1 for Body Weight Control using TRPV1(-/-) Mice and Electroacupuncture. Scientific reports. vol 5. 2016-09-23. PMID:26621679. |
moreover, the protein levels of trpv1, ppka, ppkc, and perk were increased in the dorsal root ganglion (drg) and spinal cord (sc) after ea treatment but not in the sham ea and trpv1(-/-) mice. |
2016-09-23 |
2023-08-13 |
mouse |
| Alba C de Luca, Alessandro Faroni, Adam J Rei. Dorsal root ganglia neurons and differentiated adipose-derived stem cells: an in vitro co-culture model to study peripheral nerve regeneration. Journal of visualized experiments : JoVE. issue 96. 2016-08-09. PMID:25742570. |
adipose-derived stem cells (asc) differentiated into sc phenotype are a valid alternative to sc for the set-up of a co-culture model with drg neurons to study nerve regeneration. |
2016-08-09 |
2023-08-13 |
rat |
| Alba C de Luca, Alessandro Faroni, Adam J Rei. Dorsal root ganglia neurons and differentiated adipose-derived stem cells: an in vitro co-culture model to study peripheral nerve regeneration. Journal of visualized experiments : JoVE. issue 96. 2016-08-09. PMID:25742570. |
the present work presents a detailed and reproducible step-by-step protocol to harvest both drg neurons and asc from adult rats; to differentiate asc towards a sc phenotype; and combines the two cell types in a direct co-culture system to investigate the interplay between neurons and sc in the peripheral nervous system. |
2016-08-09 |
2023-08-13 |
rat |
| Crystal Acosta, Claudia Cortes, Khaled Altaweel, Heather MacPhee, Britta Hoogervorst, Harpreet Bhullar, Brain MacNeil, Mahmoud Torabi, Frank Burczynski, Michael Peter Namak. Immune System Induction of Nerve Growth Factor in an Animal Model of Multiple Sclerosis: Implications in Re-Myelination and Myelin Repair. CNS & neurological disorders drug targets. vol 14. issue 8. 2016-07-07. PMID:25801841. |
however, its function in the dorsal root ganglia (drg) and spinal cord (sc) during experimental autoimmune encephalomyelitis (eae), the inflammatory model of multiple sclerosis, is indistinct. |
2016-07-07 |
2023-08-13 |
rat |
| Crystal Acosta, Claudia Cortes, Khaled Altaweel, Heather MacPhee, Britta Hoogervorst, Harpreet Bhullar, Brain MacNeil, Mahmoud Torabi, Frank Burczynski, Michael Peter Namak. Immune System Induction of Nerve Growth Factor in an Animal Model of Multiple Sclerosis: Implications in Re-Myelination and Myelin Repair. CNS & neurological disorders drug targets. vol 14. issue 8. 2016-07-07. PMID:25801841. |
ngf mrna and protein expression were highly increased in drg and sc tissues in animals with eae. |
2016-07-07 |
2023-08-13 |
rat |
| Crystal Acosta, Claudia Cortes, Khaled Altaweel, Heather MacPhee, Britta Hoogervorst, Harpreet Bhullar, Brain MacNeil, Mahmoud Torabi, Frank Burczynski, Michael Peter Namak. Immune System Induction of Nerve Growth Factor in an Animal Model of Multiple Sclerosis: Implications in Re-Myelination and Myelin Repair. CNS & neurological disorders drug targets. vol 14. issue 8. 2016-07-07. PMID:25801841. |
our findings suggest the induction of ngf represents an adaptive response against immune-mediated neuroinflammation in the drg and sc that likely contributes to the eae attenuation. |
2016-07-07 |
2023-08-13 |
rat |
| Luis F Queme, Jessica L Ross, Peilin Lu, Renita C Hudgins, Michael P Jankowsk. Dual Modulation of Nociception and Cardiovascular Reflexes during Peripheral Ischemia through P2Y1 Receptor-Dependent Sensitization of Muscle Afferents. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 1. 2016-05-09. PMID:26740646. |
these behavioral changes corresponded to increased heat sensitivity as well as an increase in the numbers of chemosensitive group iii/iv muscle afferents as assessed by an ex vivo forepaw muscles/median and ulnar nerves/dorsal root ganglion (drg)/spinal cord (sc) recording preparation. |
2016-05-09 |
2023-08-13 |
mouse |
| Jaung-Geng Lin, Ching-Liang Hsieh, Yi-Wen Li. Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK. PloS one. vol 10. issue 6. 2016-05-02. PMID:26043006. |
this study strongly suggests that drg trpv1 overexpression and perk signaling, as well as sc trpv1 and trpv4 overexpression, mediate hyperalgesia in a mouse fm pain model. |
2016-05-02 |
2023-08-13 |
mouse |
| S Gnavi, B E Fornasari, C Tonda-Turo, G Ciardelli, M Zanetti, S Geuna, I Perrotea. The influence of electrospun fibre size on Schwann cell behaviour and axonal outgrowth. Materials science & engineering. C, Materials for biological applications. vol 48. 2015-09-16. PMID:25579965. |
the effect of gelatin fibre diameter on cell adhesion and proliferation was tested in vitro using explant cultures of schwann cells (sc) and dorsal root ganglia (drg). |
2015-09-16 |
2023-08-13 |
Not clear |
| A Torres-Espín, D Santos, F González-Pérez, J del Valle, X Navarr. Neurite-J: an image-J plug-in for axonal growth analysis in organotypic cultures. Journal of neuroscience methods. vol 236. 2015-06-16. PMID:25124852. |
previous studies in our lab proposed a method of dorsal root ganglia (drg) and spinal cord slice (sc) organotypic 3d cultures to study motor and sensory axonal regeneration. |
2015-06-16 |
2023-08-13 |
Not clear |
| Michela M Taiana, Raffaella Lombardi, Carla Porretta-Serapiglia, Emilio Ciusani, Norberto Oggioni, Jenny Sassone, Roberto Bianchi, Giuseppe Lauri. Neutralization of schwann cell-secreted VEGF is protective to in vitro and in vivo experimental diabetic neuropathy. PloS one. vol 9. issue 9. 2015-06-10. PMID:25268360. |
we examined the modulation of vegf pathway at mrna and protein level on dorsal root ganglion (drg) neurons and schwann cells (sc) induced by hyperglycaemia. |
2015-06-10 |
2023-08-13 |
rat |