| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariya M Mikhailova, Andrey A Panteleyev, Mikhail A Paltsev, Andrey A Panteleye. Spinal cord tissue affects sprouting from aortic fragments in ex vivo co-culture. Cell biology international. vol 43. issue 10. 2020-01-03. PMID:30761658. |
here, we describe an ex vivo model, representing an organotypic co-culture of aortic fragments (af) with longitudinal slices of mouse neonatal spinal cord (sc) or dorsal root ganglia (drg). |
2020-01-03 |
2023-08-13 |
mouse |
| Xinxin Guo, Xueshu Tao, Qing Tong, Tiecheng Li, Daosong Dong, Bohan Zhang, Mengnan Zhao, Tao Son. Impaired AMPK‑CGRP signaling in the central nervous system contributes to enhanced neuropathic pain in high‑fat diet‑induced obese rats, with or without nerve injury. Molecular medicine reports. vol 20. issue 2. 2019-12-11. PMID:31173269. |
sprague‑dawley rats consuming a high‑fat diet (hf) for 12 weeks developed obesity; they exhibited significantly decreased levels of phospho (p)‑ampk and increased cgrp expression levels in the spinal cord (sc) and dorsal root ganglion (drg), respectively, compared with rats consuming a low‑fat (lf) diet. |
2019-12-11 |
2023-08-13 |
rat |
| Xinxin Guo, Xueshu Tao, Qing Tong, Tiecheng Li, Daosong Dong, Bohan Zhang, Mengnan Zhao, Tao Son. Impaired AMPK‑CGRP signaling in the central nervous system contributes to enhanced neuropathic pain in high‑fat diet‑induced obese rats, with or without nerve injury. Molecular medicine reports. vol 20. issue 2. 2019-12-11. PMID:31173269. |
hf‑fed rats that underwent spared nerve injury (sni) also exhibited lower p‑ampk and higher cgrp expression levels in the sc and drg, compared with the corresponding lf‑diet rats. |
2019-12-11 |
2023-08-13 |
rat |
| Hsin-Lin Cheng, James W Russell, Eva L Feldma. IGF-I Promotes Peripheral Nervous System Myelination. Annals of the New York Academy of Sciences. vol 883. issue 1. 2019-11-20. PMID:29086912. |
we use sc/dorsal root ganglion neuron (drg) cocultures to examine the effects of igf-i on the interaction between axons and sc. |
2019-11-20 |
2023-08-13 |
Not clear |
| Jun-Yih Chen, Li-Wen Chu, Kuang-I Cheng, Su-Ling Hsieh, Yung-Shun Juan, Bin-Nan W. Valproate reduces neuroinflammation and neuronal death in a rat chronic constriction injury model. Scientific reports. vol 8. issue 1. 2019-10-28. PMID:30405207. |
we measured paw withdrawal latency (pwl) and paw withdrawal threshold (pwt) 1 day before surgery and 1, 3, 7, 14 days after cci and harvested the sciatic nerves (sn), spinal cord (sc) and dorsal root ganglia (drg) on pod 3, 7, and 14. |
2019-10-28 |
2023-08-13 |
rat |
| Jun-Yih Chen, Li-Wen Chu, Kuang-I Cheng, Su-Ling Hsieh, Yung-Shun Juan, Bin-Nan W. Valproate reduces neuroinflammation and neuronal death in a rat chronic constriction injury model. Scientific reports. vol 8. issue 1. 2019-10-28. PMID:30405207. |
vpa lowered cci-induced inflammatory proteins (pnfκb, inos and cox-2), pro-apoptotic proteins (pakt/akt and pgsk-3β/gsk-3β), proinflammatory cytokines (tnf-α and il-1β) and nuclear pnfκb activation in the sn, drg and sc in cci rats. |
2019-10-28 |
2023-08-13 |
rat |
| Yonglin Chen, Dekun Yin, Bingbing Fan, Xiang Zhu, Qiuping Chen, Yao Li, Shunxing Zhu, Rongxiang Lu, Zhongling X. Chemokine CXCL10/CXCR3 signaling contributes to neuropathic pain in spinal cord and dorsal root ganglia after chronic constriction injury in rats. Neuroscience letters. vol 694. 2019-06-21. PMID:30448292. |
following the pain course, a significant increase of cxcl10 and cxcr3 in both dorsal root ganglion (drg) neurons and spinal cord (sc) neurons was detected in rats. |
2019-06-21 |
2023-08-13 |
rat |
| Dekun Yin, Yonglin Chen, Yao Li, Rongxiang Lu, Binbin Wang, Shunxing Zhu, Bingbing Fan, Zhongling X. Interleukin-1 Receptor Associated Kinase 1 Mediates the Maintenance of Neuropathic Pain after Chronic Constriction Injury in Rats. Neurochemical research. vol 44. issue 5. 2019-06-11. PMID:30859436. |
in the present study, irak1 was found to persistently increase in the dorsal root ganglion (drg) and spinal cord (sc) during cci detected by western blot. |
2019-06-11 |
2023-08-13 |
rat |
| Dekun Yin, Yonglin Chen, Yao Li, Rongxiang Lu, Binbin Wang, Shunxing Zhu, Bingbing Fan, Zhongling X. Interleukin-1 Receptor Associated Kinase 1 Mediates the Maintenance of Neuropathic Pain after Chronic Constriction Injury in Rats. Neurochemical research. vol 44. issue 5. 2019-06-11. PMID:30859436. |
the staining further confirmed that irak1 was mainly co-located in the drg astrocytes or sc neurons, but less in the drg microglia or sc astrocytes. |
2019-06-11 |
2023-08-13 |
rat |
| Qiu-Yue Li, Hai-Yu Xu, Hong-Jun Yan. [Effect of proinflammatory factors TNF-α,IL-1β, IL-6 on neuropathic pain]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 42. issue 19. 2019-05-03. PMID:29235283. |
more and more evidences suggest that proinflammatory cytokines(pics), such as interleukin-1β(il-1β), interleukin-6(il-6) and tumor necrosis factor-α(tnf-α), are induced in the spinal cord(sc) and dorsal root ganglion (drg) under various injury conditions, and contribute to pain hypersensitivity. |
2019-05-03 |
2023-08-13 |
Not clear |
| Shaofeng Pu, Shuangyue Li, Yongming Xu, Junzhen Wu, Yingying Lv, Dongping D. Role of receptor-interacting protein 1/receptor-interacting protein 3 in inflammation and necrosis following chronic constriction injury of the sciatic nerve. Neuroreport. vol 29. issue 16. 2019-04-10. PMID:30192300. |
the mrna expression and protein levels of inflammatory factors rip1 and rip3 in the dorsal root ganglion (drg), spinal cord (sc) and hippocampus (hip) were also determined. |
2019-04-10 |
2023-08-13 |
mouse |
| Shaofeng Pu, Shuangyue Li, Yongming Xu, Junzhen Wu, Yingying Lv, Dongping D. Role of receptor-interacting protein 1/receptor-interacting protein 3 in inflammation and necrosis following chronic constriction injury of the sciatic nerve. Neuroreport. vol 29. issue 16. 2019-04-10. PMID:30192300. |
we found that paw withdrawal threshold was significantly reduced from the second day after the operation, and the levels of tumour necrosis factor-α and interferon-γ in drg, sc and hip were significantly increased on the eighth and 14th days in cci mice. |
2019-04-10 |
2023-08-13 |
mouse |
| Shaofeng Pu, Shuangyue Li, Yongming Xu, Junzhen Wu, Yingying Lv, Dongping D. Role of receptor-interacting protein 1/receptor-interacting protein 3 in inflammation and necrosis following chronic constriction injury of the sciatic nerve. Neuroreport. vol 29. issue 16. 2019-04-10. PMID:30192300. |
overall, this study showed that rip1 and rip3 were highly expressed in drg, sc and hip of the sciatic nerve in cci mice and may be involved in chronic neuroinflammation and neuronecrosis. |
2019-04-10 |
2023-08-13 |
mouse |
| Dekun Yin, Yonglin Chen, Rongxiang Lu, Bingbing Fan, Shunxing Zhu, Xingguo Xu, Zhongling X. Translocation Associated Membrane Protein 1 Contributes to Chronic Constriction Injury-Induced Neuropathic Pain in the Dorsal Root Ganglion and Spinal Cord in Rats. Journal of molecular neuroscience : MN. vol 66. issue 4. 2019-01-10. PMID:30338452. |
by western blot and staining, we found that tram1 increased in the dorsal root ganglion (drg) neurons and spinal cord (sc) neurons after cci. |
2019-01-10 |
2023-08-13 |
rat |
| Dekun Yin, Yonglin Chen, Rongxiang Lu, Bingbing Fan, Shunxing Zhu, Xingguo Xu, Zhongling X. Translocation Associated Membrane Protein 1 Contributes to Chronic Constriction Injury-Induced Neuropathic Pain in the Dorsal Root Ganglion and Spinal Cord in Rats. Journal of molecular neuroscience : MN. vol 66. issue 4. 2019-01-10. PMID:30338452. |
the upregulation of p-nf-κb expression was reversed by tram1 sirna in sc and drg, and intrathecal injection of p-nf-κb inhibitor relieved neuropathic pain. |
2019-01-10 |
2023-08-13 |
rat |
| Dale George, Paige Ahrens, Stephen Lamber. Satellite glial cells represent a population of developmentally arrested Schwann cells. Glia. vol 66. issue 7. 2018-11-05. PMID:29520852. |
based on these observations we hypothesize that sgcs represent a population of cells in the sc lineage, whose further differentiation appears to be arrested through contact with drg neuronal soma. |
2018-11-05 |
2023-08-13 |
rat |
| Sung Hyun Lee, Jae Min Lee, Yun Hong Kim, Jung Hyun Choi, Seung Hwan Jeon, Dong Kyu Kim, Hyeon Do Jeong, You Jung Lee, Hue Jung Par. Antiallodynic Effects of Bee Venom in an Animal Model of Complex Regional Pain Syndrome Type 1 (CRPS-I). Toxins. vol 9. issue 9. 2018-10-15. PMID:28914784. |
bv (1 mg/kg ; 1, 2, and 3 times) was administered into the sc layer of the hind paw, and the antiallodynic effects were investigated using the von frey test and by measuring the expression of neurokinin type 1 (nk-1) receptors in dorsal root ganglia (drg). |
2018-10-15 |
2023-08-13 |
mouse |
| Hozo Matsuoka, Kosuke Ebina, Hiroyuki Tanaka, Makoto Hirao, Toru Iwahashi, Takaaki Noguchi, Koji Suzuki, Shunsuke Nishimoto, Tsuyoshi Murase, Hideki Yoshikaw. Administration of Oxygen Ultra-Fine Bubbles Improves Nerve Dysfunction in a Rat Sciatic Nerve Crush Injury Model. International journal of molecular sciences. vol 19. issue 5. 2018-09-24. PMID:29735961. |
in vitro, oubs significantly promoted neurite outgrowth in drg neurons by activating akt signaling and sc proliferation by activating erk1/2 and jnk/c-jun signaling. |
2018-09-24 |
2023-08-13 |
rat |
| Hozo Matsuoka, Kosuke Ebina, Hiroyuki Tanaka, Makoto Hirao, Toru Iwahashi, Takaaki Noguchi, Koji Suzuki, Shunsuke Nishimoto, Tsuyoshi Murase, Hideki Yoshikaw. Administration of Oxygen Ultra-Fine Bubbles Improves Nerve Dysfunction in a Rat Sciatic Nerve Crush Injury Model. International journal of molecular sciences. vol 19. issue 5. 2018-09-24. PMID:29735961. |
oubs may improve nerve dysfunction in snc rats by promoting neurite outgrowth in drg neurons and sc proliferation. |
2018-09-24 |
2023-08-13 |
rat |
| Binbin Wang, Bingbing Fan, Qijun Dai, Xingguo Xu, Peipei Jiang, Lin Zhu, Haifeng Dai, Zhigang Yao, Zhongling Xu, Xiaojuan Li. Fascin-1 Contributes to Neuropathic Pain by Promoting Inflammation in Rat Spinal Cord. Neurochemical research. vol 43. issue 2. 2018-08-16. PMID:29052088. |
our results showed that fascin-1 increased rapidly in dorsal root ganglions (drg) and spinal cord (sc) after cci. |
2018-08-16 |
2023-08-13 |
rat |