| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anamaria Falcão Pereira, Mario Roberto Pontes Lisboa, Bruno Wesley de Freitas Alves, Cristiane Maria Pereira da Silva, Diego Bernarde Souza Dias, Karoline Luanne Santos de Menezes, Francisco Rafael Alves Santana Cesário, Jonas Costa de França, Amanda Rocha de Oliveira, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, José Alexandre Crippa, Nylane Maria Nunes de Alencar, Roberto César Pereira Lima-Júnior, Mariana Lima Val. Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors. Neurotoxicity research. vol 39. issue 6. 2021-12-03. PMID:34792764. |
cannabidiol increased cb1 in drg, reduced mechanical hyperalgesia and c-fos expression in drg and sc. |
2021-12-03 |
2023-08-13 |
mouse |
| Anamaria Falcão Pereira, Mario Roberto Pontes Lisboa, Bruno Wesley de Freitas Alves, Cristiane Maria Pereira da Silva, Diego Bernarde Souza Dias, Karoline Luanne Santos de Menezes, Francisco Rafael Alves Santana Cesário, Jonas Costa de França, Amanda Rocha de Oliveira, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, José Alexandre Crippa, Nylane Maria Nunes de Alencar, Roberto César Pereira Lima-Júnior, Mariana Lima Val. Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors. Neurotoxicity research. vol 39. issue 6. 2021-12-03. PMID:34792764. |
additionally, win 55,212-2 increased cb1 in drg, reduced mechanical hyperalgesia, cold allodynia and c-fos expression in drg and sc. |
2021-12-03 |
2023-08-13 |
mouse |
| b' Marija Juri\\xc4\\x87, Marta Balog, Vedrana Ivi\\xc4\\x87, Maria Bo\\xc5\\xa1kovi\\xc4\\x87, Benjamin Benzon, Anita Racetin, Katarina Vukojevi\\xc4\\x87, Ivana Bo\\xc4\\x8dina, Nives Kevi\\xc4\\x87, Ivana Restovi\\xc4\\x87, K\\xc3\\xa1lm\\xc3\\xa1n F Sz\\xc5\\xb1cs, R\\xc3\\xb3bert G\\xc3\\xa1sp\\xc3\\xa1r, Marija Heffer, Sandor G Vari, Natalija Filipovi\\xc4\\x8. Increased expression of dendrin in the dorsal horn of the spinal cord during stress is regulated by sex hormones. Neuropeptides. vol 86. 2021-11-12. PMID:33524899.' |
dendrin expression was present in the thoracic sc segments and the dorsal root ganglia (drg). |
2021-11-12 |
2023-08-13 |
rat |
| b' Marija Juri\\xc4\\x87, Marta Balog, Vedrana Ivi\\xc4\\x87, Maria Bo\\xc5\\xa1kovi\\xc4\\x87, Benjamin Benzon, Anita Racetin, Katarina Vukojevi\\xc4\\x87, Ivana Bo\\xc4\\x8dina, Nives Kevi\\xc4\\x87, Ivana Restovi\\xc4\\x87, K\\xc3\\xa1lm\\xc3\\xa1n F Sz\\xc5\\xb1cs, R\\xc3\\xb3bert G\\xc3\\xa1sp\\xc3\\xa1r, Marija Heffer, Sandor G Vari, Natalija Filipovi\\xc4\\x8. Increased expression of dendrin in the dorsal horn of the spinal cord during stress is regulated by sex hormones. Neuropeptides. vol 86. 2021-11-12. PMID:33524899.' |
co-localization with the α-d-galactosyl-specific isolectin b4 (ib4) in central projections of the drg neurons in the dorsal horn of the sc was 7.43 ± 3.36%, while with the calcitonin gene-related peptide (cgrp) was 8.47 ± 4.45%. |
2021-11-12 |
2023-08-13 |
rat |
| b' Marija Juri\\xc4\\x87, Marta Balog, Vedrana Ivi\\xc4\\x87, Maria Bo\\xc5\\xa1kovi\\xc4\\x87, Benjamin Benzon, Anita Racetin, Katarina Vukojevi\\xc4\\x87, Ivana Bo\\xc4\\x8dina, Nives Kevi\\xc4\\x87, Ivana Restovi\\xc4\\x87, K\\xc3\\xa1lm\\xc3\\xa1n F Sz\\xc5\\xb1cs, R\\xc3\\xb3bert G\\xc3\\xa1sp\\xc3\\xa1r, Marija Heffer, Sandor G Vari, Natalija Filipovi\\xc4\\x8. Increased expression of dendrin in the dorsal horn of the spinal cord during stress is regulated by sex hormones. Neuropeptides. vol 86. 2021-11-12. PMID:33524899.' |
dendrin expression in pain-processing areas of the sc, the drg neurons and their peripheral projections suggest possible roles in pain perception and modulation. |
2021-11-12 |
2023-08-13 |
rat |
| Daniel M Ventre, Avery Cluff, Christian Gagnon, David Diaz Vera, Ryan A Koppes, Abigail N Koppe. The effects of low intensity focused ultrasonic stimulation on dorsal root ganglion neurons and Schwann cells in vitro. Journal of neuroscience research. vol 99. issue 1. 2021-11-01. PMID:32743823. |
building upon prior work in ultrasound stimulation (us) of dorsal root ganglion (drg) neurons, the effects of us on drg neuron and schwann cell (sc) cocultures were investigated to uncover the role of scs in mediating the neuronal response to us in vitro. |
2021-11-01 |
2023-08-13 |
Not clear |
| F H G Ahlström, K Mätlik, H Viisanen, K J Blomqvist, X Liu, T O Lilius, Y Sidorova, E A Kalso, P V Rauhal. Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats. Molecular neurobiology. vol 58. issue 10. 2021-10-27. PMID:34331199. |
ipsilateral lumbar dorsal root ganglia (drg) and spinal cord (sc) segments were collected for rna-seq analysis with deseq2 on day 7. |
2021-10-27 |
2023-08-13 |
rat |
| F H G Ahlström, K Mätlik, H Viisanen, K J Blomqvist, X Liu, T O Lilius, Y Sidorova, E A Kalso, P V Rauhal. Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats. Molecular neurobiology. vol 58. issue 10. 2021-10-27. PMID:34331199. |
there were no differences between the sexes in cgrp and ib-4 in the drg or glial cell markers in the sc. |
2021-10-27 |
2023-08-13 |
rat |
| F H G Ahlström, K Mätlik, H Viisanen, K J Blomqvist, X Liu, T O Lilius, Y Sidorova, E A Kalso, P V Rauhal. Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats. Molecular neurobiology. vol 58. issue 10. 2021-10-27. PMID:34331199. |
drg and sc showed abundant changes in gene expression. |
2021-10-27 |
2023-08-13 |
rat |
| M D Recalde, C A Miguel, M V Noya-Riobó, S L González, M J Villar, M F Corone. Resveratrol exerts anti-oxidant and anti-inflammatory actions and prevents oxaliplatin-induced mechanical and thermal allodynia. Brain research. vol 1748. 2021-10-26. PMID:32866545. |
paw mechanical and thermal allodynia, oxidative stress, antioxidant, pro-inflammatory and neuronal injury/activation markers were evaluated in the sciatic nerve (sn), lumbar dorsal root ganglia (drg) and spinal cord (sc). |
2021-10-26 |
2023-08-13 |
rat |
| M D Recalde, C A Miguel, M V Noya-Riobó, S L González, M J Villar, M F Corone. Resveratrol exerts anti-oxidant and anti-inflammatory actions and prevents oxaliplatin-induced mechanical and thermal allodynia. Brain research. vol 1748. 2021-10-26. PMID:32866545. |
the mrna levels of the transcription factor nfκb and the pro-inflammatory cytokine tnfα were found to be upregulated both in lumbar drg and sc. |
2021-10-26 |
2023-08-13 |
rat |
| Myriam L Velandia-Romero, Jaime E Castellanos, Marlén Martínez-Gutiérre. In vivo differential susceptibility of sensory neurons to rabies virus infection. Journal of neurovirology. 2021-10-21. PMID:23959650. |
some authors have suggested that the virus inoculated at the periphery is captured and transported to cns only by motor neurons; however, it has been reported that dorsal root ganglia (drg) sensory neurons capture and transport the virus to the spinal cord (sc) and then to the brain. |
2021-10-21 |
2023-08-12 |
mouse |
| Myriam L Velandia-Romero, Jaime E Castellanos, Marlén Martínez-Gutiérre. In vivo differential susceptibility of sensory neurons to rabies virus infection. Journal of neurovirology. 2021-10-21. PMID:23959650. |
in conclusion, we observed that rabv inoculated in the plantar footpad is captured preferentially by large sensory neurons and is transported to the drg, where it replicates and is spread to the sc using transynaptic jumps, infecting sensory and motor neurons at the same level before ascending to the brain. |
2021-10-21 |
2023-08-12 |
mouse |
| Xin-Jie Ning, Xin-Hua Lu, Jun-Cheng Luo, Chuan Chen, Qun Gao, Zhang-Yu Li, Hui Wan. Molecular mechanism of microRNA-21 promoting Schwann cell proliferation and axon regeneration during injured nerve repair. RNA biology. vol 17. issue 10. 2021-07-08. PMID:32507001. |
after mir-21 over-expression sc (mimic-mir-21) group, control sc (control-mir-21) group and blank sc (rsc96) group were constructed, sc proliferation was determined by cck-8, cell cycle was analysed by flow cytometry, dorsal root ganglion neuron (drgn) axon regeneration was observed after drgn was cultured with scs for 7 days, the expressions of |
2021-07-08 |
2023-08-13 |
Not clear |
| Martial Caillaud, Nipa H Patel, Wisam Toma, Alyssa White, Danielle Thompson, Jared Mann, Tammy H Tran, Jane L Roberts, Justin L Poklis, John W Bigbee, Xianjun Fang, David A Gewirtz, M Imad Dama. A Fenofibrate Diet Prevents Paclitaxel-Induced Peripheral Neuropathy in Mice. Cancers. vol 13. issue 1. 2021-05-08. PMID:33383736. |
pipn is thought to be a consequence of alterations of mitochondrial function, hyperexcitability of neurons, nerve fiber loss, oxidative stress and neuroinflammation in dorsal root ganglia (drg) and spinal cord (sc). |
2021-05-08 |
2023-08-13 |
mouse |
| b' Marija Juri\\xc4\\x87, Julia Zeitler, Katarina Vukojevi\\xc4\\x87, Ivana Bo\\xc4\\x8dina, Maximilian Grobe, Genia Kretzschmar, Mirna Saraga-Babi\\xc4\\x87, Natalija Filipovi\\xc4\\x8. Expression of Connexins 37, 43 and 45 in Developing Human Spinal Cord and Ganglia. International journal of molecular sciences. vol 21. issue 24. 2021-03-04. PMID:33302507.' |
this study characterized and compared the specific spatio-temporal expression patterns of connexins (cxs) 37, 43 and 45 during early human developmental stages (since the 5th until the 10th developmental week) in the spinal cord (sc) and dorsal root ganglia (drg) using double immunofluorescence and transmission electron microscopy. |
2021-03-04 |
2023-08-13 |
human |
| b' Marija Juri\\xc4\\x87, Julia Zeitler, Katarina Vukojevi\\xc4\\x87, Ivana Bo\\xc4\\x8dina, Maximilian Grobe, Genia Kretzschmar, Mirna Saraga-Babi\\xc4\\x87, Natalija Filipovi\\xc4\\x8. Expression of Connexins 37, 43 and 45 in Developing Human Spinal Cord and Ganglia. International journal of molecular sciences. vol 21. issue 24. 2021-03-04. PMID:33302507.' |
we found the expression of all three investigated cxs during early human development in all the areas of interest, in the sc, drg, developing paravertebral ganglia of the sympathetic trunk, notochord and all three meningeal layers, with predominant expression of cx37. |
2021-03-04 |
2023-08-13 |
human |
| Ruyue Chen, Xiaoming Yang, Bin Zhang, Shengran Wang, Shuangxi Bao, Yun Gu, Shiying L. EphA4 Negatively Regulates Myelination by Inhibiting Schwann Cell Differentiation in the Peripheral Nervous System. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31798398. |
in order to explore the roles of epha4 in myelination in the peripheral nervous system, we used a combination of (1) a co-culture model of dorsal root ganglion (drg) explants and scs, (2) a sc differentiation model induced by db-camp, and (3) a regeneration model of crushed sciatic nerves in rats. |
2020-10-01 |
2023-08-13 |
rat |
| Allison M Barry, Julia R Sondermann, Jan-Hendrik Sondermann, David Gomez-Varela, Manuela Schmid. Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord. Frontiers in molecular neuroscience. vol 11. 2020-09-29. PMID:30154697. |
we applied quantitative proteome profiling to build a comprehensive protein compendium of three regions of the pain neuraxis in mice: the sciatic nerve (sn), the dorsal root ganglia (drg), and the spinal cord (sc). |
2020-09-29 |
2023-08-13 |
mouse |
| Rongxiang Lu, Bingbing Fan, Dekun Yin, Yao Li, Binbin Wang, Shunxing Zhu, Yonglin Chen, Zhongling X. Receptor for activated C kinase 1 mediates the chronic constriction injury-induced neuropathic pain in the rats' peripheral and central nervous system. Neuroscience letters. vol 712. 2020-09-23. PMID:31491465. |
by western blot and staining, we found that rack1 protein changed in dorsal root ganglion (drg) neurons and spinal cord (sc) neurons except glial cells after cci. |
2020-09-23 |
2023-08-13 |
rat |