All Relations between sc and drg

Publication Sentence Publish Date Extraction Date Species
Alon Lai, Denise Iliff, Kashaf Zaheer, Jennifer Gansau, Damien M Laudier, Venetia Zachariou, James C Iatridi. Annulus Fibrosus Injury Induces Acute Neuroinflammation and Chronic Glial Response in Dorsal Root Ganglion and Spinal Cord-An In Vivo Rat Discogenic Pain Model. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339040. af injury induced moderate ivd degeneration with acute and broad spinal inflammation that progressed to drg to sc changes within days and weeks, respectively. 2024-02-10 2024-02-12 rat
Alon Lai, Denise Iliff, Kashaf Zaheer, Jennifer Gansau, Damien M Laudier, Venetia Zachariou, James C Iatridi. Annulus Fibrosus Injury Induces Acute Neuroinflammation and Chronic Glial Response in Dorsal Root Ganglion and Spinal Cord-An In Vivo Rat Discogenic Pain Model. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339040. this study used an in vivo rat annulus fibrosus (af) injury-driven discogenic pain model to investigate the acute and chronic changes in ivd degeneration and spinal inflammation, as well as sensitization, inflammation, and remodeling in dorsal root ganglion (drg) and spinal cord (sc) dorsal horn. 2024-02-10 2024-02-12 rat
Alon Lai, Denise Iliff, Kashaf Zaheer, Jennifer Gansau, Damien M Laudier, Venetia Zachariou, James C Iatridi. Annulus Fibrosus Injury Induces Acute Neuroinflammation and Chronic Glial Response in Dorsal Root Ganglion and Spinal Cord-An In Vivo Rat Discogenic Pain Model. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339040. we conclude that af injury-driven ivd degeneration induces acute spinal, drg, and sc inflammatory crosstalk with sustained glial responses in both drgs and sc, leading to chronic sc sensitization and neural plasticity. 2024-02-10 2024-02-12 rat
Ricardo S Harripaul, Elisabetta S Morini, Monica Salani, Emily Logan, Emily Grace Kirchner, Jessica Bolduc, Anil Chekuri, Benjamin Currall, Rachita Yadav, Serkan Erdin, Michael E Talkowski, Dadi Gao, Susan Slaugenhaup. Transcriptome analysis in a humanized mouse model of familial dysautonomia reveals tissue-specific gene expression disruption in the peripheral nervous system. bioRxiv : the preprint server for biology. 2023-10-09. PMID:37808686. comparison of fd and control transcriptomes from dorsal root ganglion (drg), trigeminal ganglion (tg), medulla (med), cortex, and spinal cord (sc) showed significantly more differentially expressed genes (degs) in the pns than the cns. 2023-10-09 2023-10-15 mouse
Natalia Malek, Jakub Mlost, Magdalena Kostrzewa, Jolanta Rajca, Katarzyna Starowic. Description of Novel Molecular Factors in Lumbar DRGs and Spinal Cord Factors Underlying Development of Neuropathic Pain Component in the Animal Model of Osteoarthritis. Molecular neurobiology. 2023-09-21. PMID:37731080. our studies provided molecular records on abnormal activation of pain transmission markers in drg and sc during development of oa that are responsible for the manifestation of neuropathic features. 2023-09-21 2023-10-07 rat
Clara Mutschler, Shaline V Fazal, Nathalie Schumacher, Andrea Loreto, Michael P Coleman, Peter Arthur-Farra. Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann cell/neuron cocultures. Journal of cell science. 2023-08-29. PMID:37642648. myelinating schwann cell (sc)- dorsal root ganglion (drg) neuron cocultures are an important technique for understanding cell-cell signalling and interactions during peripheral nervous system (pns) myelination, injury, and regeneration. 2023-08-29 2023-09-07 mouse
Hyelin Ji, Kyung-Ran Kim, Jang-Joon Park, Ju Youn Lee, Yeomoon Sim, Heonsik Choi, Sujeong Ki. Combination gene delivery reduces spinal cord pathology in rats with peripheral neuropathic pain. The journal of pain. 2023-07-13. PMID:37442406. pathological phenomena, such as hyperactivation of sensory neurons and inflammation, are observed in both the dorsal root ganglion (drg) and spinal cord (sc). 2023-07-13 2023-08-14 rat
Hyelin Ji, Kyung-Ran Kim, Jang-Joon Park, Ju Youn Lee, Yeomoon Sim, Heonsik Choi, Sujeong Ki. Combination gene delivery reduces spinal cord pathology in rats with peripheral neuropathic pain. The journal of pain. 2023-07-13. PMID:37442406. we investigated the effects of kls-2031 (recombinant adeno-associated viruses expressing glutamate decarboxylase 65, glial cell-derived neurotrophic factor, and interleukin-10) delivered to the drg on aberrant neuronal excitability and neuroinflammation in the sc of rats with peripheral np. 2023-07-13 2023-08-14 rat
Thomas Grüter, Nuwin Mohamad, Niklas Rilke, Alina Blusch, Melissa Sgodzai, Seray Demir, Xiomara Pedreiturria, Katharina Lemhoefer, Barbara Gisevius, Aiden Haghikia, Anna Lena Fisse, Jeremias Motte, Ralf Gold, Kalliopi Pitarokoil. Propionate exerts neuroprotective and neuroregenerative effects in the peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 4. 2023-01-20. PMID:36669102. we were able to demonstrate an antioxidative and neuroregenerative effect of propionate on sc and drg mediated by ffar3-induced histone acetylases expression. 2023-01-20 2023-08-14 Not clear
Thomas Grüter, Nuwin Mohamad, Niklas Rilke, Alina Blusch, Melissa Sgodzai, Seray Demir, Xiomara Pedreiturria, Katharina Lemhoefer, Barbara Gisevius, Aiden Haghikia, Anna Lena Fisse, Jeremias Motte, Ralf Gold, Kalliopi Pitarokoil. Propionate exerts neuroprotective and neuroregenerative effects in the peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 4. 2023-01-20. PMID:36669102. ffar3, but not ffar2, expression was evident on sc and drg. 2023-01-20 2023-08-14 Not clear
Zijian Zhou, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kanek. Specific Cellular Effects of Low Bortezomib Concentrations on Purified Cultures of Schwann Cells, Satellite Glial Cells, Macrophages, and Dorsal Root Ganglion Neurons. Biological & pharmaceutical bulletin. vol 46. issue 1. 2023-01-03. PMID:36596518. taken together, low concentrations of btz can cause sc dedifferentiation (i.e., demyelination), increased gfap level in sgc, and decreased expression levels of sensor and transducer ion channels in drg neurons (i.e., numbness feeling). 2023-01-03 2023-08-14 Not clear
Soultana Markopoulou, Lina Vardouli, Fotios Dimitriadis, Dimitra Psalla, Alexandros Lambropoulos, Apostolos Apostolidi. Effect of Bladder Injection of OnabotulinumtoxinA on the Central Expression of Genes Associated with the Control of the Lower Urinary Tract: A Study in Normal Rats. International journal of molecular sciences. vol 23. issue 22. 2022-11-26. PMID:36430896. to investigate a possible central mechanism of action of botulinum toxin a (bont/a) following injection in the bladder, complementary to the acknowledged peripheral bladder effect, we studied changes in the expression of neuropeptides and receptors involved in lower urinary tract function in the spinal cord (sc) and dorsal root ganglia (drg) of normal rats following bont/a bladder injection. 2022-11-26 2023-08-14 rat
Tiantian Zheng, Linliang Wu, Shaolan Sun, Jiawei Xu, Qi Han, Yifan Liu, Ronghua Wu, Guicai L. Co-culture of Schwann cells and endothelial cells for synergistically regulating dorsal root ganglion behavior on chitosan-based anisotropic topology for peripheral nerve regeneration. Burns & trauma. vol 10. 2022-09-08. PMID:36071954. however, the synergistic regulation of ec and sc co-culture of drg behavior on anisotropic topologies is still rarely reported. 2022-09-08 2023-08-14 Not clear
Anda Mann, Bibiane Steinecker-Frohnwieser, Aida Naghilou, Flavia Millesi, Paul Supper, Lorenz Semmler, Sonja Wolf, Lena Marinova, Lukas Weigl, Tamara Weiss, Christine Radtk. Nuclear Magnetic Resonance Treatment Accelerates the Regeneration of Dorsal Root Ganglion Neurons Frontiers in cellular neuroscience. vol 16. 2022-04-14. PMID:35418835. to provide first insight into a possible effect of nmrt on cells involved in peripheral nerve regeneration, this study investigated whether nmrt is able to influence the cellular behavior of primary sc and dorsal root ganglion (drg) neuron cultures 2022-04-14 2023-08-13 Not clear
Yuan-Shan Zeng, Ying Ding, Hao-Yu Xu, Xiang Zeng, Bi-Qin Lai, Ge Li, Yuan-Huan M. Electro-acupuncture and its combination with adult stem cell transplantation for spinal cord injury treatment: A summary of current laboratory findings and a review of literature. CNS neuroscience & therapeutics. 2022-02-17. PMID:35174644. this would elicit the dorsal root ganglion neurons to secrete excess amounts of calcitonin gene-related peptide centrally in the sc. 2022-02-17 2023-08-13 Not clear
Wen Xue, Yunfan Kong, Rafay Abu, Pooja Roy, Sung-Ho Huh, Mitchell Kuss, Vikas Kumar, Bin Dua. Regulation of Schwann Cell and DRG Neurite Behaviors within Decellularized Peripheral Nerve Matrix. ACS applied materials & interfaces. 2022-02-11. PMID:35148064. in this study, dnhs from rat sciatic nerves were prepared, and their effects on schwann cell (sc) and dorsal root ganglion (drg) neurite behaviors were evaluated and compared to commercial rat tail type i collagen (col) hydrogels in three-dimensional (3d) environments. 2022-02-11 2023-08-13 rat
Anamaria Falcão Pereira, Mario Roberto Pontes Lisboa, Bruno Wesley de Freitas Alves, Cristiane Maria Pereira da Silva, Diego Bernarde Souza Dias, Karoline Luanne Santos de Menezes, Francisco Rafael Alves Santana Cesário, Jonas Costa de França, Amanda Rocha de Oliveira, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, José Alexandre Crippa, Nylane Maria Nunes de Alencar, Roberto César Pereira Lima-Júnior, Mariana Lima Val. Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors. Neurotoxicity research. vol 39. issue 6. 2021-12-03. PMID:34792764. cb1, cb2, and c-fos expression were assessed in dorsal root ganglia (drg), spinal cord (sc), trigeminal ganglia (tg), spinal trigeminal nucleus caudalis (sp5c), and periaqueductal gray (pag). 2021-12-03 2023-08-13 mouse
Anamaria Falcão Pereira, Mario Roberto Pontes Lisboa, Bruno Wesley de Freitas Alves, Cristiane Maria Pereira da Silva, Diego Bernarde Souza Dias, Karoline Luanne Santos de Menezes, Francisco Rafael Alves Santana Cesário, Jonas Costa de França, Amanda Rocha de Oliveira, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, José Alexandre Crippa, Nylane Maria Nunes de Alencar, Roberto César Pereira Lima-Júnior, Mariana Lima Val. Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors. Neurotoxicity research. vol 39. issue 6. 2021-12-03. PMID:34792764. oxaliplatin increased cb1 in drg, sc, tg, sp5c, and ventrolateral pag, with no interference in cb2 expression. 2021-12-03 2023-08-13 mouse
Anamaria Falcão Pereira, Mario Roberto Pontes Lisboa, Bruno Wesley de Freitas Alves, Cristiane Maria Pereira da Silva, Diego Bernarde Souza Dias, Karoline Luanne Santos de Menezes, Francisco Rafael Alves Santana Cesário, Jonas Costa de França, Amanda Rocha de Oliveira, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, José Alexandre Crippa, Nylane Maria Nunes de Alencar, Roberto César Pereira Lima-Júnior, Mariana Lima Val. Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors. Neurotoxicity research. vol 39. issue 6. 2021-12-03. PMID:34792764. cannabidiol increased cb1 in drg, reduced mechanical hyperalgesia and c-fos expression in drg and sc. 2021-12-03 2023-08-13 mouse
Anamaria Falcão Pereira, Mario Roberto Pontes Lisboa, Bruno Wesley de Freitas Alves, Cristiane Maria Pereira da Silva, Diego Bernarde Souza Dias, Karoline Luanne Santos de Menezes, Francisco Rafael Alves Santana Cesário, Jonas Costa de França, Amanda Rocha de Oliveira, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, José Alexandre Crippa, Nylane Maria Nunes de Alencar, Roberto César Pereira Lima-Júnior, Mariana Lima Val. Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors. Neurotoxicity research. vol 39. issue 6. 2021-12-03. PMID:34792764. additionally, win 55,212-2 increased cb1 in drg, reduced mechanical hyperalgesia, cold allodynia and c-fos expression in drg and sc. 2021-12-03 2023-08-13 mouse